{"title":"Ceftizoxime in the treatment of uncomplicated gonorrhoea.","authors":"R C Spencer, T Smith, M D Talbot","doi":"10.1136/sti.60.2.90","DOIUrl":null,"url":null,"abstract":"<p><p>A total of 74 men and 26 women with uncomplicated gonorrhoea were treated with ceftizoxime sodium 0.5 g intramuscularly. The cure rate was 99% and included successful treatment of four infections due to beta-lactamase producing organisms. The minimum inhibitory concentrations (MICs) of ceftizoxime in vitro were very much lower than those of penicillin and cefuroxime, and side effects were minimal. We conclude that ceftizoxime is effective against Neisseria gonorrhoeae in vivo and in vitro.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.90","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The British Journal of Venereal Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/sti.60.2.90","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6
Abstract
A total of 74 men and 26 women with uncomplicated gonorrhoea were treated with ceftizoxime sodium 0.5 g intramuscularly. The cure rate was 99% and included successful treatment of four infections due to beta-lactamase producing organisms. The minimum inhibitory concentrations (MICs) of ceftizoxime in vitro were very much lower than those of penicillin and cefuroxime, and side effects were minimal. We conclude that ceftizoxime is effective against Neisseria gonorrhoeae in vivo and in vitro.
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