The British Journal of Venereal Diseases最新文献

{"title":"Herpes vaccine.","authors":"A Mindel","doi":"10.1136/sti.60.3.204-a","DOIUrl":"https://doi.org/10.1136/sti.60.3.204-a","url":null,"abstract":"","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"204-5"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.204-a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17390598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexually transmitted diseases: extract from the annual report of the Chief Medical Officer of the Department of Health and Social Security for the year 1982.","authors":"","doi":"10.1136/sti.60.3.199","DOIUrl":"https://doi.org/10.1136/sti.60.3.199","url":null,"abstract":"Since the incidence of the sexually transmitted diseases (STD) started to rise 25 years ago there has been a steady increase in the numbers of new cases reported from the clinics. This increase reached a peak in 1980 when over 500 000 new cases were registered in the United Kingdom as a whole. The number of cases registered in England in the same year was 458 979 (469 140 in England and Wales). In 1981 the figures for England were 479 924 (England and Wales 491 014). The figures from the annual returns for individual clinics in England show that 50% of all the new cases were seen in clinics in the four Thames regions. This fact has important implications for short and long term planning. The increase in the number of new cases attending the clinics over the past quarter of a century has been due to the more recently recognised sexually transmissible agents such as Chlamydia trachomatis, Ureaplasma urealyticum, Gardnerella vaginalis,","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"199-203"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.199","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17603840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virus diseases and the skin","authors":"D. Robertson","doi":"10.1136/sti.60.3.207","DOIUrl":"https://doi.org/10.1136/sti.60.3.207","url":null,"abstract":"This book gives information on virus diseases which produce lesions of the skin and includes reference to conjunctiva and mucosa when they are appreciably affected by virus disease. The first five chapters deal with general aspects of virus infection, and the succeeding ten cover specific virus infections of the skin. The introduction considers the structure of viruses, and is illustrated by diagrams and photomicrographs. The process of replication is described without recourse to biochemical detail, and a simplified classification of human viruses is assembled in tabular form. Host defence and pathogenesis are subjects usefully covered, and some aspects of the problem of persisting virus infection are discussed. Techniques for laboratory diagnosis are described in brief with illustrations that are useful for those not familiar with such techniques. The chapter on treatment makes reference (without detail) to amantadine, methisazone, idoxuridine, cytosine arabinoside, and adenosine arabinoside. Acyclovir is mentioned but its value, limitations, and clinical use are not covered. Infections with herpes simplex virus, varicella zoster virus, Epstein-Barr virus, measles, and rubella are given a chapter each. The chapter on enterovirus infections includes reference to diseases due to coxsackie virus (herpangina; hand, foot, and mouth disease; lymphonodular pharyngitis), echovirus, and other viruses of the group. A brief account of variola is included for historical interest because of occasional accidental infection and because of the possibility that animal pox viruses might infect man, mutate, and produce disease of comparable severity. Cow pox, orf, milker's node, and molluscum contagiosum complete the list of pox virus diseases. The chapter on human papillomavirus deals with wart lesions of various forms and in various sites including the palate. Genital warts receive brief consideration, but no mention is made of the flat warts of the cervix or of the problem of cervical dysplasia. In connection with herpes genitalis and genital warts, the importance of excluding other sexually transmitted diseases is not discussed. The questions so often raised by sufferers are not given sufficient emphasis in this book, and those engaged in genitourinary medicine will have to look elsewhere for further details of these virus diseases. The penultimate chapter deals with skin diseases that are probably of viral origin, such as roseola infantum, erythema infectiosum, pityriasis rosea, pityriasis lichenoides, and lichen planus. Finally the authors discuss virus infections that may show rashes but do not generally occur in sufficient frequency, or are not sufficiently characteristic, to be pathognomonic. Hepatitis B virus and papular acrodermatitis of childhood, Marburg disease, Lassa fever, other viral haemorrhagic fevers are included in this chapter. Among the togavirus infections, with names evocative to the reviewer, are dengue, West Nile fever, chikungunya, and","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"94 1","pages":"207 - 207"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79450886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of uncomplicated gonorrhoea with rosoxacin (acrosoxacin).","authors":"K B Lim,&nbsp;V S Rajan,&nbsp;Y C Giam,&nbsp;E O Lui,&nbsp;E H Sng,&nbsp;K L Yeo","doi":"10.1136/sti.60.3.157","DOIUrl":"https://doi.org/10.1136/sti.60.3.157","url":null,"abstract":"<p><p>An open study was designed primarily to evaluate the efficacy of rosoxacin in the treatment of gonorrhoea caused by penicillinase producing Neisseria gonorrhoeae (PPNG) and non-PPNG strains. A total of 199 patients (99 men and 100 women) satisfactorily completed follow up examinations, 50 men and 50 women having received rosoxacin 300 mg orally and the remainder having received kanamycin 2 g intramuscularly. Rosoxacin achieved an overall cure rate of 94% (96.7% for PPNG and 90% for non-PPNG strains). In patients treated with kanamycin the overall cure rate was 89.9% (92.7% for PPNG and 83.3% for non-PPNG strains). A correlation between treatment failures and minimum inhibitory concentrations (MICs) of rosoxacin was noted in non-PPNG strains but not in PPNG strains. Side effects which were mild and self limiting were noted in 15 of 100 patients treated with rosoxacin. The high failure rates associated with non-PPNG strains requiring MICs of 0.125 mg/l and the observation of a substantial rise in the MICs for isolates after treatment is of concern. Otherwise, rosoxacin in a single dose of 300 mg appears to be safe and effective for the treatment of uncomplicated gonorrhoea.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"157-60"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.157","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17487510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sheffield medium for cultivation of Haemophilus ducreyi.","authors":"S Hafiz,&nbsp;M G McEntegart,&nbsp;G R Kinghorn","doi":"10.1136/sti.60.3.196","DOIUrl":"https://doi.org/10.1136/sti.60.3.196","url":null,"abstract":"<p><p>Our interest in the role of Haemophilus ducreyi in genital ulceration led us to examine the various media commonly used for the cultivation of the organism. We describe an improved medium for the routine isolation of H ducreyi. In comparative studies using 50 test strains originally isolated in the United Kingdom, Canada, the United States of America, and Kenya, the new medium proved superior to three standard media in requiring a shorter incubation period to first visible growth, giving larger colonies in the same period, and making possible a starch aggregation test which we have found helpful in the presumptive identification of H ducreyi from clinical material.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"196-8"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.196","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17666641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Failure of pivampicillin in treating chlamydial infections.","authors":"H Hagdrup,&nbsp;J Kristensen,&nbsp;J Scheibel","doi":"10.1136/sti.60.3.204","DOIUrl":"https://doi.org/10.1136/sti.60.3.204","url":null,"abstract":"","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"204"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17786612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The activity of rosoxacin, fosfomycin, cefotiam, and spectinomycin on beta-lactamase producing Neisseria gonorrhoeae.","authors":"N Dickgiesser,&nbsp;P Kuntz","doi":"10.1136/sti.60.3.154","DOIUrl":"https://doi.org/10.1136/sti.60.3.154","url":null,"abstract":"<p><p>We measured the activity of rosoxacin, fosfomycin, cefotiam, and spectinomycin against 51 isolates of beta-lactamase producing Neisseria gonorrhoeae, all of which were susceptible to each drug at sufficient concentrations. The development of strains of penicillinase producing N gonorrhoeae (PPNG) which are resistant to spectinomycin can therefore be avoided, as there are alternative drugs.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"154-6"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.154","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17390031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibodies to cytomegalovirus in homosexual and heterosexual men attending an STD clinic.","authors":"A Mindel,&nbsp;S Sutherland","doi":"10.1136/sti.60.3.189","DOIUrl":"https://doi.org/10.1136/sti.60.3.189","url":null,"abstract":"<p><p>We studied the prevalence of antibody to cytomegalovirus (CMV) in 262 men (132 homosexual, 20 bisexual, and 108 heterosexual) attending the sexually transmitted diseases (STD) clinic at this hospital. Antibody to CMV at a titre of 1/4 or more was found in 92% of the homosexuals, 80% of the bisexuals, and 56% of the heterosexuals (p less than 0.0001). Among heterosexuals, but not homosexuals, nationality and social class showed a significant association with antibody to CMV. In both heterosexuals and homosexuals a history of gonorrhoea was more common in patients with antibody to CMV than in those without it. A similar finding was seen in heterosexual men with a history of non-specific urethritis (NSU). Using a series of log linear models, sexual orientation was shown to be the most important determinant of antibody to CMV in this population.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 3","pages":"189-92"},"PeriodicalIF":0.0,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.3.189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17390597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for cervical intraepithelial neoplasia and cancer in the Sheffield STD clinic.","authors":"A B Alawattegama","doi":"10.1136/sti.60.2.117","DOIUrl":"https://doi.org/10.1136/sti.60.2.117","url":null,"abstract":"<p><p>I undertook a prospective study of the incidence of histologically confirmed cervical intraepithelial neoplasia (CIN) and cancer in women attending a sexually transmitted disease (STD) clinic, and correlated the findings to cervical cytology reports, age, and history of STD of the affected women. Of 2017 women screened, 75 (3.7%) had dyskaryotic cervical smears. Colposcopically directed biopsy tests gave an overall detection rate of 0.55% for CIN3, which was similar to the national average. The false negative rate was 2.9% and cytology tests alone underestimated the degree of pathological change in 12 (30%) of 40 women with mild dyskaryosis. Women under 20 years old made up 43% of those with CIN1 and 38% of those with CIN2. The detection rate of CIN3 was 0.65% for women aged 15-34, which was higher than the national average and suggested earlier onset of CIN3 in our clinic population. There was a high association between genital warts and cervical precancer. This preliminary study confirms the need for routine non-selective screening of women attending STD clinics by cervical cytology tests, colposcopic examination, and biopsy tests where indicated.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"117-20"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17602954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contact tracing in the control of STD in Ibadan, Nigeria.","authors":"M C Asuzu,&nbsp;B O Ogunbanjo,&nbsp;I O Ajayi,&nbsp;A B Oyediran,&nbsp;A O Osoba","doi":"10.1136/sti.60.2.114","DOIUrl":"https://doi.org/10.1136/sti.60.2.114","url":null,"abstract":"<p><p>Contact tracing carried out at this clinic was analysed as part of measures for control of sexually transmitted disease (STD). Results showed that 50% of 156 contacts could not be traced at all for various reasons, and that 47% of the contacts were brought in through persuasion by index patients who had been counselled at the clinic. Only four contacts were traced, and two of these attended the clinic. Index patient cooperation is thus identified as the most important factor in the success of contact tracing, because of the high level of illiteracy and poor communications facilities in Nigeria, compared with industrialised countries.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"114-6"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.114","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17758893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}