THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019最新文献

{"title":"Numerical analysis of conjugate porous media for increasing heat transfer rate in fixed bed spheres","authors":"F. R. Purnadiana, Prabowo, H. Sasongko","doi":"10.1063/1.5138291","DOIUrl":"https://doi.org/10.1063/1.5138291","url":null,"abstract":"Porous media becomes a potential alternative for cooling technology since it has large contact surface area that strongly enhance heat transfer and exchanging energy within pore channel. A computational fluid dynamics of conjugate heat transfer and periodic boundary condition were applied in FLUENT 6.3.26. Simulations of fixed bed spheres as porous media inside pipe flow were carried out in the range of Reynolds number 5000 to 80000. Simulation methodology was validated by analytical prediction. In the range of Reynolds number 100 – 6000 is very good agreement, however in the range of Reynolds number above 6000 - 10000 just fairly agree. This is caused by the fact that in the range of Reynolds number above 6000 analytical model does not use turbulence model. Fluctuation effects are just considered as dispersion. The results shows that the fixed bed spheres for porous structure gives the highest value of the cooling effectiveness than the other porous structures except for ReD ≤ 10000, the cooling effectiveness of the discrete porous structure is higher compared to the analyzed fixed bed porous structures. At ReD = 15,000 the fixed bed spheres gives 28%, 65% and 160% higher effectiveness compared to the discrete porous structure, 60° broken ribs and 90° continuous ribs, respectively.Porous media becomes a potential alternative for cooling technology since it has large contact surface area that strongly enhance heat transfer and exchanging energy within pore channel. A computational fluid dynamics of conjugate heat transfer and periodic boundary condition were applied in FLUENT 6.3.26. Simulations of fixed bed spheres as porous media inside pipe flow were carried out in the range of Reynolds number 5000 to 80000. Simulation methodology was validated by analytical prediction. In the range of Reynolds number 100 – 6000 is very good agreement, however in the range of Reynolds number above 6000 - 10000 just fairly agree. This is caused by the fact that in the range of Reynolds number above 6000 analytical model does not use turbulence model. Fluctuation effects are just considered as dispersion. The results shows that the fixed bed spheres for porous structure gives the highest value of the cooling effectiveness than the other porous structures except for ReD ≤ 10000, the cooling effectiv...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87688578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High progesterone levels on the day of hCG administration in controlled ovarian hyperstimulation procedures reduce the expression of progesterone receptors in the endometrium Macaca nemestrina","authors":"Nurhuda, Rosalina Thuffi, Dwi Ari Pudjianto, R. Muharam, N. Mudjihartini, Andhea Debby Pradhita, K. Kusmardi","doi":"10.1063/1.5139369","DOIUrl":"https://doi.org/10.1063/1.5139369","url":null,"abstract":"","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"96 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87689732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Numerical study on the performance and flow field of varied conical basin for efficient gravitational water vortex power plant","authors":"D. S. Pamuji, Nizam Effendi, D. Sugati","doi":"10.1063/1.5138256","DOIUrl":"https://doi.org/10.1063/1.5138256","url":null,"abstract":"Nowadays, utilization of hydropower is still focussed on the development of large dams which have an effect on the natural environment and are often opposed by the people in the region. Producing electricity from small water resources, especially using the gravitational vortex method has currently attracted the interest of researchers. In this paper, a numerical study of the effect of vortex pool variation on the performance and flow field of gravitational water vortex power plant (GWVPP) are investigated. Numerical study based on the volume of fluid (VOF) method is developed in ANSYS FLUENT code program for analyzing the parametric studies of GWVPP. Cylindrical vortex pool coupled with gravitation type water turbine based on Nishi and Inagaki (2017) research, are modified become conical vortex pool type by varying the ratio of inlet diameter and outlet diameter (Din/Dout) by 3.26; 4.9; and 6.12. Turbulent model is approached using RNG k-epsilon and boundary conditions are set 2.838 kg/s for inlet mass flow rate, 0 Pa for open and outlet boundary. As a beginning result, the computational values of this study and experimental data of the torque and turbine output from Nishi and Inagaki (2017) agreed with one another. Later, for conical basin with variation of Din/Dout, it can be shown that the maximum velocity profile achieved in nearly to the discharge hole, in order from 6.12; 4.9; followed by 3.26 of the Din/Dout ratio respectively. It is supported by the increase in the Din/Dout ratio or decrease output hole, the air area increase and creat greater vortex circulation.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75882576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Sundanese music on daytime sleep quality based on EEG signal","authors":"D. E. Kusumandari, M. A. Suhendra, M. Rizqyawan, A. I. Simbolon, A. Turnip, P. Wardono, Adriani Rizka","doi":"10.1063/1.5139394","DOIUrl":"https://doi.org/10.1063/1.5139394","url":null,"abstract":"In theory, Daytime sleep is decreasing stress and increasing mood, focus, cognitive function. In this research, we would like to know the impact of Sundanese music on sleep quality based EEG signals in the daytime. The extraction features used wavelet Daubechies D8 level 7 and Fast Fourier Transform to divide it to alpha and theta band ranges. The experimental results from 10 subjects showed that using Sundanese music as treatment can make brain activity become calm and relax. Also, using T-Test to find relationships and influences between pre and post-treatment and The Result of T-Test showed that the value (p) is below 0.05 (p< 0.05), then these treatment has affected and it can to be alternative for day time sleep therapy.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72807921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Girder extension effect on earthquake resilience of ship unloader crane: A numerical study","authors":"Suwarno, A. Syaifudin","doi":"10.1063/1.5138359","DOIUrl":"https://doi.org/10.1063/1.5138359","url":null,"abstract":"Girder of a ship unloader crane (SUC) with a rated capacity of 1250 t/h has to be extended in order to follow jetty upgrading. The girder extension is limited by the railway span of gantry crane and the capacity of belt conveyor, which are maintained. This simulation aims to determine the effect of girder extension on the vulnerability of SUC to earthquake shocks in Indonesian region. A new method is proposed to evaluate earthquake resilience of crane structure that is not anchored to the ground, based on an equivalent static load of earthquake shock. The equivalent static simulation is carried out using ANSYS Mechanical APDL R18 on the 3d-truss model of SUC, which is generated based on the general arrangement drawing. To investigate the influence of earthquake shocks on the SUC structure, three variations of girder extension is applied, i.e. 3m, 6m, and 9m. The applied load consists of the SUC operating load and the earthquake load that works on the SUC structure’s supports. The earthquake resilience of SUC after girder extension is evaluated by comparing the reaction forces that occur in the supports. The simulations indicated that the girder extension can reduce the earthquake resilience of SUC, depending on the direction of the earthquake propagation.Girder of a ship unloader crane (SUC) with a rated capacity of 1250 t/h has to be extended in order to follow jetty upgrading. The girder extension is limited by the railway span of gantry crane and the capacity of belt conveyor, which are maintained. This simulation aims to determine the effect of girder extension on the vulnerability of SUC to earthquake shocks in Indonesian region. A new method is proposed to evaluate earthquake resilience of crane structure that is not anchored to the ground, based on an equivalent static load of earthquake shock. The equivalent static simulation is carried out using ANSYS Mechanical APDL R18 on the 3d-truss model of SUC, which is generated based on the general arrangement drawing. To investigate the influence of earthquake shocks on the SUC structure, three variations of girder extension is applied, i.e. 3m, 6m, and 9m. The applied load consists of the SUC operating load and the earthquake load that works on the SUC structure’s supports. The earthquake resilience of ...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91239221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antiviral activity of Ceiba pentandra and Eugenia uniflora leaf extracts to dengue virus serotype-2 in Huh 7it-1 cell line","authors":"B. Dewi, M. Angelina, Sabda Ardiantara, Agung Riyanto Prakoso, H. Desti, T. M. Sudiro","doi":"10.1063/1.5139340","DOIUrl":"https://doi.org/10.1063/1.5139340","url":null,"abstract":"Dengue Fever (DF) is an infectious disease caused by dengue virus (DENV) infection which is transmitted by Aedes aegypti and Aedes albopictus mosquito bite. There are approximately 50 million DENV cases annually in the world with 500 thousand cases hospitalized. Incidence rate of DENV infection is increasing in Indonesia every year. Specific antiviral that can inhibit or mitigate the progression of the disease have been investigated for many decades. However, until now, management of DENV patients is only supportive. Specific antiviral drug to DENV is not available yet. The objective of this study is to determine antiviral activity of Ceiba pentandra and Eugenia uniflora leaf extract against DENV replication in Huh7it-1 cell line. Study design was an experimental study with a Focus assay and MTT assay to determine the effectivity and toxicity, respectively. Ceiba pentandra leaf extract showed IC50, CC50 and SI of 15.49 µg/ml, 81.1 µg/ml and 5.23. In other hand, E. uniflora revealed IC50, CC50, and SI of 19.83 µg/ml, 134.42 µg/ml and 6.78. We concluded that C. pentandra and E. uniflora leaf extract have potential as antiviral drug to DENV. Further studies are needed to explore the substance of C. pentandra and E. uniflora leaf extract that have antiviral activities to DENV.Dengue Fever (DF) is an infectious disease caused by dengue virus (DENV) infection which is transmitted by Aedes aegypti and Aedes albopictus mosquito bite. There are approximately 50 million DENV cases annually in the world with 500 thousand cases hospitalized. Incidence rate of DENV infection is increasing in Indonesia every year. Specific antiviral that can inhibit or mitigate the progression of the disease have been investigated for many decades. However, until now, management of DENV patients is only supportive. Specific antiviral drug to DENV is not available yet. The objective of this study is to determine antiviral activity of Ceiba pentandra and Eugenia uniflora leaf extract against DENV replication in Huh7it-1 cell line. Study design was an experimental study with a Focus assay and MTT assay to determine the effectivity and toxicity, respectively. Ceiba pentandra leaf extract showed IC50, CC50 and SI of 15.49 µg/ml, 81.1 µg/ml and 5.23. In other hand, E. uniflora revealed IC50, CC50, and SI of 1...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83494838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finite element analysis of porous stemmed hip prosthesis for children","authors":"D. P. Malau, M. S. Utomo, D. Annur, T. Asmaria, Yogi Prabowo, A. Rahyussalim, S. Supriadi, M. I. Amal","doi":"10.1063/1.5139393","DOIUrl":"https://doi.org/10.1063/1.5139393","url":null,"abstract":"Femur bone stress shielding is known to be a significant factor in aseptic loosening or failure of hip replacements. This paper considers the development of a porous stemmed hip implant for children patient in order to reduce the effects of stress shielding and also maintaining acceptably low levels of stress in other areas of prosthesis. By using finite element modeling, the stresses in the proximal femur using porous stem were calculated and analyzed. The developed model is considered safe in terms of mechanical strength. The porous region does not bring significant effect on stress distribution but produces a considerable amount of compressive strain.Femur bone stress shielding is known to be a significant factor in aseptic loosening or failure of hip replacements. This paper considers the development of a porous stemmed hip implant for children patient in order to reduce the effects of stress shielding and also maintaining acceptably low levels of stress in other areas of prosthesis. By using finite element modeling, the stresses in the proximal femur using porous stem were calculated and analyzed. The developed model is considered safe in terms of mechanical strength. The porous region does not bring significant effect on stress distribution but produces a considerable amount of compressive strain.","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78229580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of an optimum method for power generation using flare gas from oil refinery plants","authors":"B. A. Dwiyantoro, Farai William Saungweme","doi":"10.1063/1.5138290","DOIUrl":"https://doi.org/10.1063/1.5138290","url":null,"abstract":"Today the world is facing global warming as one of its main issues, this is mainly caused by a rise in carbon dioxide and other greenhouse gases concentration in the atmosphere. Flaring is one of the major causes of the increase in greenhouse gases, 145 billion cubic meters of natural gas was flared in 2018. Indonesia being an archipelago nation and located near the equator suffers greatly from these global warming impacts. The impacts include environmental degradation, health implications and economic effects. This study is intended to develop a power plant configuration that can be adopted at an already existing plant to use flare gas as a complementary fuel. The energy of the flare gas will be converted into mechanical energy through thermal power plant instead of being vented as presently. Two possible plant configurations were developed and simulated using Thermo-flow and the results were compared. Both configurations employ the combined cycle concept, where a gas turbine is coupled with a steam turbine. The main difference between the two configurations is that configuration 1 uses a Heat Recovery Steam Generator whilst the second configuration uses common Heat Exchangers in-between the gas turbine and the Rankine cycle. The results show that configuration 1 would generate a net power of 40.948MW whilst configuration 2 would generate 32.924MW.Today the world is facing global warming as one of its main issues, this is mainly caused by a rise in carbon dioxide and other greenhouse gases concentration in the atmosphere. Flaring is one of the major causes of the increase in greenhouse gases, 145 billion cubic meters of natural gas was flared in 2018. Indonesia being an archipelago nation and located near the equator suffers greatly from these global warming impacts. The impacts include environmental degradation, health implications and economic effects. This study is intended to develop a power plant configuration that can be adopted at an already existing plant to use flare gas as a complementary fuel. The energy of the flare gas will be converted into mechanical energy through thermal power plant instead of being vented as presently. Two possible plant configurations were developed and simulated using Thermo-flow and the results were compared. Both configurations employ the combined cycle concept, where a gas turbine is coupled with a steam turb...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76870067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of use of solar panels on micro scale fixed-wing UAV type as a power recharging system","authors":"I. Ridwan, Alfindo","doi":"10.1063/1.5135553","DOIUrl":"https://doi.org/10.1063/1.5135553","url":null,"abstract":"Unmanned Aerial Vehicle (UAV), popularly known as drone, is a type of aerial explorer robot that can be controlled remotely to carry out certain missions. One type of UAV for carrying out a flying mission is a fixed-wing type. It is widely used for mapping and monitoring equipment. This type of drone has limited flight time because the battery used has limited capacity, especially in micro scale UAVs with±2 kg weight. Therefore, sometimes the drone must return to replace the battery before the mission is complete. In this condition, experimental research is needed with the addition of solar panels in the wings to increase flight time. The method used to solve this problem is by designing an electronic component UAV which is integrated with a solar panel charger system, an airframe with 2.125 kg flight weight, 18 m/s cruise speed, 1.63 m wingspan, and 0.37 m2 wing surface area. The solar cells used are Sunpower C60, are arranged in series of 10 pieces with 21% maximum efficiency and 0.132 m2 total surface area. The solar panel charger system is integrated with UAV electronic components that use the Tarot2814 brushless motor with 290 W maximum power, ESC 30 A, 4S Sony VTC6 3000 mAh battery, LM2587 5A step-up module, and Arduino solar charge controller. The results of the research prove that micro scale UAV-Solar can add flight time for 2 minutes with an intensity of solar radiation average of 929.46 W/m2. During flight testing, solar cells produce an average power of 15.14 W with a maximum efficiency of 14.8% and a total flight time of 15 minutes. This proves that the addition of solar panels to UAV micro scale fixed wing types can be realized.Unmanned Aerial Vehicle (UAV), popularly known as drone, is a type of aerial explorer robot that can be controlled remotely to carry out certain missions. One type of UAV for carrying out a flying mission is a fixed-wing type. It is widely used for mapping and monitoring equipment. This type of drone has limited flight time because the battery used has limited capacity, especially in micro scale UAVs with±2 kg weight. Therefore, sometimes the drone must return to replace the battery before the mission is complete. In this condition, experimental research is needed with the addition of solar panels in the wings to increase flight time. The method used to solve this problem is by designing an electronic component UAV which is integrated with a solar panel charger system, an airframe with 2.125 kg flight weight, 18 m/s cruise speed, 1.63 m wingspan, and 0.37 m2 wing surface area. The solar cells used are Sunpower C60, are arranged in series of 10 pieces with 21% maximum efficiency and 0.132 m2 total surface ...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88673903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of adding microalgae Spirulina platensis in making antibacterial soap","authors":"Martha Fransisca, Dianursanti","doi":"10.1063/1.5139330","DOIUrl":"https://doi.org/10.1063/1.5139330","url":null,"abstract":"The infection of methicillin-resistant Staphylococcus aureus (MRSA) has increased to 8% in 2017 in Indonesia. This infection commonly occurs in hospital thus, individuals must maintain personal hygiene such as using antibacterial soap. Several commercial antibacterial soap in Indonesia still use triclosan and triclocarban as antibacterial agent. This is a problem because they have been banned by Food and Drug Administration (FDA) in 2017. The use of them can disturb human reproduction system which lead to infertility and destroy algal growth. This study utilized Spirulina platensis and virgin coconut oil (VCO) as fatty acid source which reacted with sodium hydroxide to make soap. Furthermore, VCO also acted as antibacterial agent which can kill bacteria. Film-formed soap is expected to lessen soap and water waste. This soap was made by the hot process method at a temperature of 65°C. The examination done were free alkali, free fatty acid values, pH values, water content and antibacterial activity toward S. aureus. The result showed that all sample met the Indonesian National Standard (SNI) of hard soap. The use of VCO can substitute chemical-based antibacterial agent in soap because it has same ability in killing S. aureus in soap (at 25% dilution) which resulted in safer and environmentally friendly soap. The optimum composition in soap making were found in the use of 1 g S. platensis.The infection of methicillin-resistant Staphylococcus aureus (MRSA) has increased to 8% in 2017 in Indonesia. This infection commonly occurs in hospital thus, individuals must maintain personal hygiene such as using antibacterial soap. Several commercial antibacterial soap in Indonesia still use triclosan and triclocarban as antibacterial agent. This is a problem because they have been banned by Food and Drug Administration (FDA) in 2017. The use of them can disturb human reproduction system which lead to infertility and destroy algal growth. This study utilized Spirulina platensis and virgin coconut oil (VCO) as fatty acid source which reacted with sodium hydroxide to make soap. Furthermore, VCO also acted as antibacterial agent which can kill bacteria. Film-formed soap is expected to lessen soap and water waste. This soap was made by the hot process method at a temperature of 65°C. The examination done were free alkali, free fatty acid values, pH values, water content and antibacterial activity toward S...","PeriodicalId":22239,"journal":{"name":"THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84906380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}