Spinal Cord Series and Cases最新文献

{"title":"The feasibility and effect of a peer-facilitated, remote handcycling sport program for aging adults with spinal cord injury or disease: a mixed methods case series.","authors":"Lovisa Cheung, Robert Buren, Natasha L Benn, Charlene Alton, B Catharine Craven, Susan Marzolini, Kristin E Musselman","doi":"10.1038/s41394-025-00721-1","DOIUrl":"10.1038/s41394-025-00721-1","url":null,"abstract":"<p><strong>Study design: </strong>Concurrent mixed methods case series.</p><p><strong>Objectives: </strong>To examine the feasibility and effect of a peer-facilitated, remote handcycling sport program on physical, psychological, and social health of individuals with spinal cord injury or disease (SCI/D) aged ≥50 years.</p><p><strong>Setting: </strong>Participants' homes.</p><p><strong>Methods: </strong>Manual wheelchair users aged ≥50 years with chronic SCI/D were eligible. Participants completed remote, group-based handcycling at moderate-vigorous intensity twice weekly for 12 weeks, co-led by a physiotherapist and peer with SCI/D. Handcycling duration was progressively increased to 45 min. Outcome measures were completed at three timepoints (pre-, post-, 12 weeks post-training). True change was assessed using the two-standard deviation band method for the Spinal Cord Independence Measure, Moorong Self-Efficacy Scale, Exercise Self-Efficacy Scale (ESES), Positive Affect and Well-Being Scale, and Multidimensional Scale of Perceived Social Support, and minimal detectable change for the 6 min Push Test (6MPT). Semi-structured interviews were analyzed using thematic analysis.</p><p><strong>Results: </strong>Five participants enrolled; four completed the program and one was withdrawn following fractures unrelated to program. Overall, divergence was observed when comparing quantitative and qualitative findings. Interview data revealed participants perceived physical, psychological, and social health improvements, but there was minimal change in quantitative scores. A few instances of convergence were noted; e.g., immediately post-intervention, SP01 experienced improvement in 6MPT distance, which corroborated SP01's perceived physical health improvements. At 12-week follow-up, SP03 experienced reduction in ESES score, which aligned with SP03's reports of skin issues limiting sport.</p><p><strong>Conclusions: </strong>Remote handcycling provided some health benefits for participants with SCI/D aged ≥50 years.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"26"},"PeriodicalIF":0.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12420813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using the Theoretical Domains Framework to identify strategies to support the implementation of the guidelines for the physiotherapy management of people with spinal cord injury: a qualitative study.","authors":"K E Tranter, L A Harvey, J Chu, J Ilha, M Ben, L W Chen, J V Glinsky","doi":"10.1038/s41394-025-00719-9","DOIUrl":"https://doi.org/10.1038/s41394-025-00719-9","url":null,"abstract":"<p><strong>Study design: </strong>Qualitative design.</p><p><strong>Aim: </strong>The aim of the study was to (i) determine the perspectives of therapists and people with spinal cord injury (SCI) on our recently developed Australian and New Zealand Clinical Practice Guidelines for the physiotherapy management of people with SCI, and (ii) understand the barriers and facilitators to the rollout of the Guidelines and identify implementation strategies to support their uptake.</p><p><strong>Setting: </strong>Hospital and community SCI services, Australia.</p><p><strong>Methods: </strong>Twenty-one therapists and 10 people with SCI were interviewed one-on-one or within focus groups. The interviews captured perspectives of therapists and people with SCI on the Guidelines as well as barriers and facilitators to the rollout of the Guidelines. The interviews with therapists were guided by the Theoretical Domains Framework (TDF). All interviews were transcribed and thematically coded. Barriers and facilitators were then linked to the COM-B model (Capability, Opportunity, Motivation - Behaviour) to identify implementation strategies.</p><p><strong>Results: </strong>The barriers to implementation of the Guidelines identified by therapists were lack of knowledge and skill, lack of resources and challenges associated with working within large organisations. Facilitators to the uptake of the Guidelines were providing education, skill training, Guideline champions, awareness, and two-way communication between patient and therapist. Fourteen implementation strategies were identified.</p><p><strong>Conclusion: </strong>Both therapists and people with SCI thought the Guidelines were a useful tool to improve the quality of care provided to people with SCI across various health settings. Facilitators identified in this study are being used to guide current implementation projects to enhance the uptake of the Guidelines.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"25"},"PeriodicalIF":0.9,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12394610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral quantitative computed tomography and blood biomarkers in children with spinal cord disorders.","authors":"Jamie Ellis, Mary P Galea, Adam Scheinberg, Peter Simm","doi":"10.1038/s41394-025-00720-2","DOIUrl":"https://doi.org/10.1038/s41394-025-00720-2","url":null,"abstract":"<p><strong>Study design: </strong>Cross-sectional study OBJECTIVES: Spinal cord disorders (SCD) in children are uncommon, but for those affected the musculoskeletal effects can be severe. Little is known about bone health and pediatric SCD experiences in Australia. We aimed to describe bone and muscle development following pediatric SCD.</p><p><strong>Setting: </strong>The Royal Children's Hospital, Melbourne, Australia METHODS: Ten participants with SCD were recruited and underwent peripheral quantitative computed tomography (pQCT) scans and blood tests to observe bone health biochemistry.</p><p><strong>Results: </strong>Z-scores (mean ± SD) for trabecular density at the 4% tibial site were lower in non-weightbearing children compared to weightbearing children (-6.5 ± 1.5 vs. -2.4 ± 1.5, Total cohort: -5.0 ± 2.6). At the 66% site, muscle cross-sectional area (-4.7 ± 2.2 vs. -1.1 ± 1.7, Total cohort: -3.1 ± 2.7), strength strain index (-3.4 ± 1.3 vs. -1.0 ± 0.4, Total cohort: -2.5 ± 1.6) and total bone cross-sectional area (-2.4 ± 0.8 vs. 0.4 ± 1.7, Total cohort: -1.2 ± 1.9) were also lower in non-weightbearing children. Radial Z-scores revealed reduced total bone area at the 4% site (-3.5 ± 2.1) and strength strain index at the 65% site (-1.3 ± 1.8) in all participants. Serum testing revealed alkaline phosphatase was reduced in three participants, one of whom was also deficient in phosphate and 25-Hydroxyvitamin D.</p><p><strong>Conclusions: </strong>Weightbearing status influenced multiple outcomes including trabecular density, muscle cross-sectional area and bone strength in the tibia.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"24"},"PeriodicalIF":0.9,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12368188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gait training using powered robotic exoskeleton for a person with spinal cord injury: a case report.","authors":"Sunpreet Singh Hanspal, Harvinder Singh Chhabra, Ankush Gera, Gouree Sengar","doi":"10.1038/s41394-025-00716-y","DOIUrl":"10.1038/s41394-025-00716-y","url":null,"abstract":"<p><strong>Introduction: </strong>Robotic Exoskeleton-assisted gait training is an emerging approach in spinal cord injury (SCI) rehabilitation. This case report evaluates the effectiveness of Powered-Robotic exoskeleton-based gait training in an individual with chronic paraplegia.</p><p><strong>Case presentation: </strong>A 31-year-old male with T12 SCI due to fall underwent a four-week structured rehabilitation program incorporating powered robotic exoskeleton training (Exo-Rehabilitation) alongside conventional therapy. The patient participated in 15 sessions over four weeks of intervention, with progressive gait training phases, transition from assisted weight-bearing to independent crutch-assisted walking. Functional, neurological and psychological outcomes were assessed pre and post intervention. Clinical measures include, Function in sitting test (FIST), Walking Index for Spinal cord injury (WISCI-II), ISNSCI lower extremity motor scores (LEMS), Spinal Cord Independence measure (SCIM III), 6-min walk test (6MWT) and Quebec User Evaluation of Satisfaction with Assistive Technology 2.0 (QUEST 2.0). Patient reported outcomes and attendance were also recorded. The patient demonstrated better, sitting balance, and functional mobility, with enhanced psychological well-being and adherence to rehabilitation.</p><p><strong>Discussion: </strong>Robotic Exoskeleton-assisted gait training may be safe and a feasible approach to improve mobility, balance, and functional independence in SCI patients. Robotic overground exoskeleton-based gait training may represent a significant step forward in bridging the gap between conventional therapy and advanced technology, offering new hope for functional recovery and independence in individuals with Chronic SCI.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"23"},"PeriodicalIF":0.9,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Botulinum toxin in preventing complications of muscle flap reconstruction in spinal cord injury/disease.","authors":"Luca Negosanti, Paola Rucci, Siriana Landi, Francesca Bettini, Gaia Musumeci, Pamela Salucci, Luca Gaiani, Rossella Sgarzani","doi":"10.1038/s41394-025-00718-w","DOIUrl":"10.1038/s41394-025-00718-w","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective single-centre study on spinal cord injury/disease (SCI/D) persons with spasticity, treated with muscle flaps reconstruction for pressure injury (PI) between July 2013 and January 2022.</p><p><strong>Objectives: </strong>PI is a common complication in SCI/D. Neuro-muscular (NM) blockade with botulinum toxin-A (BTX) and intrathecal baclofen were used to treat associated spasticity in the reconstruction with muscle flaps, because spasms can lead to flap detachment and failure of the reconstruction, and compared with drug treatment alone or no drug.</p><p><strong>Setting: </strong>Tertiary Rehabilitation Hospital for SCI/D in Italy.</p><p><strong>Methods: </strong>Data were extracted from medical records. The characteristics of the sample were summarized using absolute and percentage frequencies, median and interquartile range or mean ± standard deviation, as appropriate. Characteristics and outcomes of PI were reported using the PI as the unit of analysis. Categorical variables were compared between groups with and without BTX-NM blockade using the chi-squared test and continuous variables were compared using Mann-Whitney's test. Statistical analyses were carried out using Stata, version 18.0 (StataCorp LLC, 2023).</p><p><strong>Results: </strong>In this study of 46 persons with 54 PIs, the treatment of spasticity consisted of medication, BTX-NM blockade and intrathecal baclofen. The use of BTX-NM was associated with a significantly lower minor complication rate (13.4% vs 59%, p = 0.003) and a significantly shorter time to complete recovery (44 vs 58 days, p = 0.006).</p><p><strong>Conclusion: </strong>BTX-NM can be used to prevent muscle spasms and may lead to better outcomes by reducing the minor complication rates and time to recovery.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"21"},"PeriodicalIF":0.9,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anxiety and adjustment following SCI: a transdiagnostic psychological intervention combining Cognitive Behavioural Therapy (CBT) and Coping Effectiveness Training (CET).","authors":"J Duff, L C Grant","doi":"10.1038/s41394-025-00713-1","DOIUrl":"10.1038/s41394-025-00713-1","url":null,"abstract":"<p><strong>Introduction: </strong>Spinal cord injury (SCI) is a life-changing experience which can result in a substantial range of psychological challenges. Although anxiety is elevated following SCI, evidence suggests that it is underreported and underdiagnosed, with consequences for long-term physical and mental health. In the UK, Cognitive Behavioural Therapy (CBT) is recommended as the first-line intervention for anxiety. However, people with SCI often face additional and complex challenges, which can limit the efficacy of protocol-delivered CBT. Pre-injury vulnerabilities can compound psychological challenges by influencing primary and secondary appraisals and perceived manageability of injury, resulting in poorer mental health and rehabilitation outcomes.</p><p><strong>Case presentation: </strong>A transdiagnostic treatment intervention using a SCI-specific adjustment model alongside CBT and Coping Effectiveness Training (CET) of an adult with post-injury anxiety and adjustment difficulties (as measured by the GAD-7 and the ADAPSS), and history of depression (as measured by the PHQ-9). Individual psychological treatment for anxiety maintenance cycles, low mood and reduction of threat appraisals are reported, alongside multidisciplinary collaboration to enhance engagement. Outcomes included improved symptoms of anxiety, reduction of loss appraisals and development of resilience appraisals.</p><p><strong>Discussion: </strong>Case studies of psychological treatment are sparse within the SCI literature. This case provides a detailed application of one of the most recognised psychological treatment modalities - CBT - and its integration with CET within an adjustment model for SCI. This study also highlights the importance of providing psychological support, psychoeducation and self-management strategies for all individuals with SCI, that is not dependent upon the degree of psychological morbidity.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"22"},"PeriodicalIF":0.9,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12297280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"O-arm navigated excision and vertebroplasty of pediatric aggressive vertebral hemangioma with compressive myelopathy: A case report.","authors":"Ajay R Kothari, Nishad V Situt, Shailesh R Hadgaonkar, Siddharth N Aiyer, Pramod D Bhilare, Parag K Sancheti","doi":"10.1038/s41394-025-00717-x","DOIUrl":"10.1038/s41394-025-00717-x","url":null,"abstract":"<p><strong>Introduction: </strong>Vertebral hemangioma (VH) is the most common angiomatous tumor usually asymptomatic and is incidentally noticed on MRI. The incidence of VH is rare in the pediatric population. The extraosseous extension is termed an Aggressive Vertebral Hemangioma (AVH) and these often need surgical management. Intraoperative stereotactic navigation for tumor excision helps in planning- localizing the tumor and delineating its margins.</p><p><strong>Case presentation: </strong>A 14-year-old boy presented with thoracic myelopathy signs. The MRI scan suggests T1 and T2 hyperintense signals within the T6 vertebral body with extramedullary extradural space occupying the lesion. The CT scan showed a \"polka dot\" appearance. Preoperative endovascular embolization followed by surgical decompression with posterior instrumented stabilization under O-arm navigation and tumor excision was planned. Cystic extradural lesion excised and vertebroplasty done at T6 level. Histopathology slides confirmed hemangioma.</p><p><strong>Discussion: </strong>The most common age of involvement is between 30 and 70 years it is rarely seen in the pediatric age group. To the best of our knowledge, fewer than 20 cases of pediatric aggressive vertebral hemangiomas have been reported. Based on a review of pediatric AVH only 4 patients have been treated with preoperative vascular embolization followed by surgical decompression and stabilization. O-arm navigated AVH excision and vertebroplasty has never been described in the literature; this being the first case. It also aids in the identification of tumor margins along with real-time monitoring of adequate resection.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"20"},"PeriodicalIF":0.9,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12284136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of nabiximols (Sativex®) on spasticity and non-motor symptoms in chronic spinal cord injury (SCI): a longitudinal prospective study.","authors":"Fernando Martins Braga, Sergiu Albu, Cecilia Mariño Fernández, Virginia Martínez Santana, Jesús Benito-Penalva, Joan Vidal Samsó","doi":"10.1038/s41394-025-00712-2","DOIUrl":"10.1038/s41394-025-00712-2","url":null,"abstract":"<p><strong>Study design: </strong>Observational, longitudinal, prospective study.</p><p><strong>Objectives: </strong>This study aimed to evaluate the effects of Nabiximols (Sativex®) on spasticity in chronic spinal cord injury (SCI) individuals refractory to conventional therapy. Secondary objectives included assessing its impact on functional independence, neuropathic pain, sleep quality, and depression.</p><p><strong>Setting: </strong>Institute Guttmann, a neurorehabilitation hospital in Badalona, Catalonia (Spain).</p><p><strong>Methods: </strong>Adult participants ( >18 years) with chronic SCI ( >6 months) and moderate to severe spasticity refractory to conventional treatments were recruited. All participants underwent baseline assessments and were followed up at one and two months after initiating treatment with nabiximols oromucosal spray, with individualised dose adjustments on a weekly basis. Assessed variables included spasticity, functional independence, neuropathic pain, sleep quality, depression, quality of life, and Patient Global Impression of Improvement (PGI-I).</p><p><strong>Results: </strong>Statistically significant improvements in spasticity were observed after one month (VAS decrease of 30%, p < 0.001; MAS decrease of 60%, p = 0.001) and two months (VAS decrease of 30%, p < 0.001; MAS decrease of 52%, p = 0.011) of treatment. A positive PGI-I was reported in 67% of participants. However, no significant changes were noted in spasms frequency, functional independence, neuropathic pain, or sleep quality. No significant differences in spasticity change or non-motor symptoms were found between participants with complete and incomplete SCI.</p><p><strong>Conclusions: </strong>Nabiximols may effectively reduce spasticity in individuals with SCI resistant to conventional therapies. Given the significant impact of spasticity associated with SCI, it could be considered a viable add-on therapy for this population.</p><p><strong>Trial registry: </strong>This clinical trial is registered in the EudraCT database under the identifier 2022-001777-31.</p><p><strong>Sponsorship: </strong>Almirall, S.A., Barcelona, Catalonia (Spain).</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"19"},"PeriodicalIF":0.7,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12271395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior cervical-thoracic spinal fixation using mandibular instrumentation to treat acute cervical spine traumatic instability in the young pediatric population.","authors":"Chani M Taggart, Paola G Pieri, Daniel G Gridley, Kote Chundu, Ramin Jamshidi, Salvatore C Lettieri, Iman Feiz-Erfan","doi":"10.1038/s41394-025-00715-z","DOIUrl":"10.1038/s41394-025-00715-z","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective review.</p><p><strong>Objective: </strong>Surgical fixation of the pediatric subaxial cervical spine poses significant challenges due to a mismatch between rigid adult cervical spine hardware and the size and shape of bone in a young (below 8 years of age) cervical spine.</p><p><strong>Setting: </strong>Arizona, USA.</p><p><strong>Methods: </strong>We conducted a retrospective review of our experience with subaxial cervical spine screw fixation using adult type mandibular instrumentation in pediatric patients younger than 8 years, symptomatic from acute traumatic cervical spine injury during the period of 2007 through 2023.</p><p><strong>Results: </strong>We identified 5 patients with the mean age of 4.4 years (range 2-6 years) who all had spinal cord injury with subluxation or dislocation at C6-7. All patients underwent posterior cervico-thoracic fixation with mandibular instrumentation from C2 to the upper thoracic spine. There was one complication of a right vertebral artery occlusion by screw placement, which did not cause harm. Suboptimal screw placement was detected in 18.4% of screws, but no revision was needed, since it was asymptomatic. All patients fused successfully without significant hardware failure. The mean time of follow up was 91 months ranging from 33-187 months.</p><p><strong>Conclusions: </strong>Mandibular screw and plate fixation was effective to treat the acutely traumatic unstable subaxial cervical spine in the young pediatric population. The rate of suboptimal screw placement may be reduced by placing shorter screws into the lamina, pedicles, or facets if the plate hole does not align for a standard trajectory needed for lateral mass or pedicle screw placement.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"18"},"PeriodicalIF":0.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of traumatic spinal cord injury in Catalonia, Spain: a 50 years' experience of a referral center.","authors":"Alejandro García-Rudolph, Mark Andrew Wright, Jesus Benito, Margarita Vallés, Martín Sassul, David Sanchez-Pinsach, Eloy Opisso, Joan Vidal, Montserrat Bernabeu","doi":"10.1038/s41394-025-00714-0","DOIUrl":"10.1038/s41394-025-00714-0","url":null,"abstract":"<p><strong>Study design: </strong>Hospital-based retrospective epidemiological research.</p><p><strong>Objectives: </strong>To describe the epidemiological and demographic characteristics of patients with traumatic spinal cord injury (TSCI) in Catalonia from 1972-2022.</p><p><strong>Setting: </strong>Neurological university hospital in Catalonia.</p><p><strong>Methods: </strong>All patients diagnosed with TSCI admitted to the hospital from 1972-2022 were retrospectively reviewed. Etiology categories, neurological level of injury, American Spinal Injury Association Impairment Scale (AIS), Functional Independence Measure (FIM), and crude incidence rates were analyzed.</p><p><strong>Results: </strong>A total of 3092 individuals with TSCI met the criteria. The crude annual incidence rate was 0.94/100,000 inhabitants. Mean age rose significantly over the years, from 27.7 (SD = 10.9) during 1972-1981 to 41.8 (SD = 17.1) during 2012-2022. The proportion of females constantly increased during 1982-2022 (18.4-23.1%). Etiologies were traffic accidents (51.8%), falls (22.0%), sports (9.8%), work-related (9.1%), suicide attempts (4.6%) and violence (2.7%). The proportion of traffic accidents dropped from 62.4% during 1982-1991 to 37.5% during 2012-2022, whereas falls increased from 14.5% during 1982-1991 to 26.0% during 2012-2022. Suicide attempts was the only etiology constantly increasing during 1972-2022 from 1-8% and with highest proportion of females (55.9%). Thoracic injuries dropped from 57.9% (1972-1981) to 38.3% (2012-2022), while cervical injuries constantly increased up to 48.8% in 2012-2022 with AIS A cases dropping and AIS D increasing. During 2002-2022, the etiologies with highest proportion of poor motor FIM at admission were sports (68.9%) and falls (63.1%).</p><p><strong>Conclusions: </strong>Our results suggest the need on prevention strategies specially addressing falls and female suicide attempts.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":"11 1","pages":"17"},"PeriodicalIF":0.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}