Substance Abuse and Rehabilitation最新文献

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Using the Theory of Planned Behavior to Explain and Predict Areca Nut Use Among Adolescents in India: An Exploratory Study. 用计划行为理论解释和预测印度青少年槟榔的使用:一项探索性研究。
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2022-09-06 eCollection Date: 2022-01-01 DOI: 10.2147/SAR.S377606
Himanshu A Gupte, Nilesh Chatterjee, Gauri Mandal
{"title":"Using the Theory of Planned Behavior to Explain and Predict Areca Nut Use Among Adolescents in India: An Exploratory Study.","authors":"Himanshu A Gupte,&nbsp;Nilesh Chatterjee,&nbsp;Gauri Mandal","doi":"10.2147/SAR.S377606","DOIUrl":"https://doi.org/10.2147/SAR.S377606","url":null,"abstract":"<p><strong>Context: </strong>Areca nut, used alone or in combination with tobacco, contributes to the high oral cancer burden in India. Used widely by adolescents, who perceive it as a harmless substance, areca nut is addictive and considered a precursor to tobacco use. Given its serious implications for addictiveness and physical health, urgent preventive interventions for areca nut use are required in India and South-East Asia. Studies examining the role of health behavior theory in explaining and predicting areca nut use and for development of its prevention among adolescents are scarce.</p><p><strong>Aim: </strong>This study explored the role of the components of Theory of Planned Behavior (TPB) such as attitudes, subjective norms, perceived behavioral control, and intention in predicting areca nut use among adolescents.</p><p><strong>Settings and design: </strong>Observational study with cross-sectional design conducted with 1884 male and female adolescents attending low-income schools in Mumbai, India.</p><p><strong>Methods and material: </strong>Self-administered surveys were used to gather data on age, gender, behavioral factors and areca nut use.</p><p><strong>Statistical analysis used: </strong>Chi-square and Mann Whitney test for bivariate and logistic regression for multivariate analysis.</p><p><strong>Results: </strong>Around 27.2% of 1884 participants were areca nut users. The mean age of users was 13.75 years. Intention-to-use and perceived behavioral control were statistically significant predictors of actual areca nut use (p<0.001). The components of TPB such as attitude, perceived subjective social norms, and perceived behavioral control had a statistically significant effect on the intention-to-use areca nut (p<0.05).</p><p><strong>Conclusion: </strong>This exploratory study indicates that constructs from TPB could help us understand and predict areca nut use. However, more rigorous future research is required to generate insights that help craft effective theory-based behavioral interventions for areca nut prevention and cessation in adolescents.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2022-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/82/sar-13-47.PMC9464035.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33464848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cocaine Use Disorder (CUD): Current Clinical Perspectives. 可卡因使用障碍(CUD):当前的临床观点。
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2022-09-03 eCollection Date: 2022-01-01 DOI: 10.2147/SAR.S337338
Elizabeth K C Schwartz, Noah R Wolkowicz, Joao P De Aquino, R Ross MacLean, Mehmet Sofuoglu
{"title":"Cocaine Use Disorder (CUD): Current Clinical Perspectives.","authors":"Elizabeth K C Schwartz,&nbsp;Noah R Wolkowicz,&nbsp;Joao P De Aquino,&nbsp;R Ross MacLean,&nbsp;Mehmet Sofuoglu","doi":"10.2147/SAR.S337338","DOIUrl":"https://doi.org/10.2147/SAR.S337338","url":null,"abstract":"<p><p>Cocaine use disorder (CUD) is a devastating disorder, impacting both individuals and society. Individuals with CUD face many barriers in accessing treatment for CUD, and most individuals with CUD never receive treatment. In this review, we provide an overview of CUD, including risk factors for CUD, common co-occurring disorders, acute and chronic effects of cocaine use, and currently available pharmacological and behavioral treatments. There are no FDA-approved pharmacological treatments for CUD. Future studies with larger sample sizes and testing treatment combinations are warranted. However, individuals with CUD and co-occurring disorders (eg, a mood or anxiety disorder) may benefit from medication treatments. There are behavioral interventions that have demonstrated efficacy in treating CUD - contingency management (CM) and cognitive-behavioral therapy for substance use disorders (CBT-SUD) in particular - however many barriers remain in delivering these treatments to patients. Following the discussion of current treatments, we highlight some promising emerging treatments, as well as offer a framework that can be used in building a treatment plan for individuals with CUD.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2022-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d8/4a/sar-13-25.PMC9451050.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33462472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Current Insights on the Impact of Gamma-Hydroxybutyrate (GHB) Abuse. γ -羟基丁酸盐(GHB)滥用影响的最新见解。
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2022-02-09 eCollection Date: 2022-01-01 DOI: 10.2147/SAR.S315720
Emma Tay, Wing Kwan Winky Lo, Bridin Murnion
{"title":"Current Insights on the Impact of Gamma-Hydroxybutyrate (GHB) Abuse.","authors":"Emma Tay,&nbsp;Wing Kwan Winky Lo,&nbsp;Bridin Murnion","doi":"10.2147/SAR.S315720","DOIUrl":"https://doi.org/10.2147/SAR.S315720","url":null,"abstract":"<p><p>Recreational gamma-hydroxybutyrate (GHB) use, although less common than other substance use, is increasingly recognised and is over-represented in emergency toxicology presentations. This narrative review summarizes GHB pharmacology, current patterns of use, potential harms and management of GHB toxicity and withdrawal. There is a complex interplay between GHB and GABA as GHB is both a prodrug and metabolite of GABA and GHB activates both GHB and GABA receptors. GHB is rapidly absorbed, with effects seen within minutes of ingestion. Metabolism is non-linear at higher doses. While GHB is listed as a controlled substance, its precursor's gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) are easily available as both have industrial applications. National surveys indicate low rates of GHB use, with identification of high-risk populations in men who have sex with men and polysubstance users. GHB is one of the three drugs most commonly used in chemsex. GHB is often co-ingested with other interacting psychoactive substances. Acute toxicity is dose-dependent, and management is supportive care. Withdrawal management is generally with benzodiazepines with addition of baclofen for more severe withdrawal. Barbiturates may have a role. Titration and tapering of pharmaceutical GHB is commonly used in the Netherlands. Complicated withdrawal with delirium may require intensive care and treatment with intravenous sedation. There are high rates of relapse after withdrawal and medications for longer-term management are currently being investigated. Chronic use is associated with poorer mental, physical and sexual health, social dysfunction and poor work performance. Laboratory detection is complicated as GHB is an endogenous substance with a short half-life, and therefore not often routinely assayed in the clinical setting. Future research should focus on improving GHB detection and management of GHB withdrawal and dependence. Interventions specific for high-risk groups should be developed and assessed.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/6f/sar-13-13.PMC8843350.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39930280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
The Impact of Stigma on People with Opioid Use Disorder, Opioid Treatment, and Policy. 耻辱感对阿片类药物使用障碍患者的影响,阿片类药物治疗和政策。
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2022-01-25 eCollection Date: 2022-01-01 DOI: 10.2147/SAR.S304566
Ali Cheetham, Louisa Picco, Anthony Barnett, Dan I Lubman, Suzanne Nielsen
{"title":"The Impact of Stigma on People with Opioid Use Disorder, Opioid Treatment, and Policy.","authors":"Ali Cheetham,&nbsp;Louisa Picco,&nbsp;Anthony Barnett,&nbsp;Dan I Lubman,&nbsp;Suzanne Nielsen","doi":"10.2147/SAR.S304566","DOIUrl":"https://doi.org/10.2147/SAR.S304566","url":null,"abstract":"<p><p>Illicit drug use disorders are the most stigmatised health conditions worldwide, and stigma acts as a meaningful barrier to treatment entry and treatment provision. In the context of dramatically rising opioid-related harms, it is critical that we understand the drivers of stigma and how it affects opioid use disorder treatment and policy. The aim of this narrative review is to discuss how opioid-related stigma impacts treatment provision and harm reduction, and provide potential strategies to reduce stigma at a social and structural level. We used the Framework for Integrating Normative Influences on Stigma (FINIS) to identify sources of opioid-related stigma at the macro (structural stigma), meso (public stigma) and micro (internalised stigma) levels. Reducing stigma requires strategies that target multiple levels, however addressing inequity in the laws, regulations, and rules that segregate people with opioid and other substance use disorders from mainstream society is essential.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/84/sar-13-1.PMC8800858.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39885817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Harmful Alcohol Use Among Patients with Tuberculosis in Gedeo Zone, Southern Ethiopia. 埃塞俄比亚南部Gedeo地区结核病患者有害酒精使用情况
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2022-01-01 DOI: 10.2147/SAR.S384921
Kalkidan Yohannes, Getinet Ayano, Kusse Koirita Toitole, Henok Mulatu Teferi, Hirbaye Mokona
{"title":"Harmful Alcohol Use Among Patients with Tuberculosis in Gedeo Zone, Southern Ethiopia.","authors":"Kalkidan Yohannes,&nbsp;Getinet Ayano,&nbsp;Kusse Koirita Toitole,&nbsp;Henok Mulatu Teferi,&nbsp;Hirbaye Mokona","doi":"10.2147/SAR.S384921","DOIUrl":"https://doi.org/10.2147/SAR.S384921","url":null,"abstract":"<p><strong>Introduction: </strong>Alcohol consumption among patients with tuberculosis is on the rise. There is evidence that alcohol consumption negatively affects treatment outcomes for these populations. Due to this, a substantial number of people relapse, withdraw from treatment, or even die as a result of their alcohol addiction. Despite this, little research has been conducted on the factors associated with the harmful use of alcohol by this group of people in Ethiopia. The purpose of this study was to determine the prevalence and associated factors of harmful alcohol use among patients with tuberculosis in the Gedeo Zone, southern Ethiopia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted at healthcare facilities. Four hundred and fifteen participants aged 18 and older were recruited using a systematic random sampling method. Data on sociodemographic factors, clinical factors, social support, perceptions of the stigma associated with tuberculosis, and depression were collected using structured and validated instruments. Measurement of harmful alcohol consumption was conducted using the AUDIT.</p><p><strong>Results: </strong> The prevalence of harmful alcohol use among tuberculosis patients was 20% (95% CI; 16.1-24.2%). There is a significant correlation between medical comorbidity (AOR = 2.44, 95% CI: 1.29-4.62), disease duration (≥12 months) (AOR = 2.88, 95% CI: 1.03-3.04), and being male (AOR = 2.10, 95% CI: 1.17-3.77) with harmful alcohol consumption.</p><p><strong>Conclusion: </strong>Our study revealed that alcohol consumption was high among tuberculosis patients. The presence of comorbidities, being male, and having a long-term illness were significant predictors of harmful alcohol consumption. It is imperative to screen patients who have suffered from chronic tuberculosis for an extended period of time. It is also pertinent to screen patients with comorbid medical conditions for alcohol abuse. Screening for alcohol abuse at an early stage can prevent poor treatment outcomes as well as the effects of comorbid medical conditions and harmful use of alcohol.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c5/d7/sar-13-117.PMC9760035.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10763181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of the Pharmacist in Combating the Opioid Crisis: An Update. 药剂师在对抗阿片类药物危机中的作用:更新。
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2022-01-01 DOI: 10.2147/SAR.S351096
Lucas Kosobuski, Carolyn O'Donnell, Cynthia P Koh-Knox Sharp, Nathaniel Chen, Laura Palombi
{"title":"The Role of the Pharmacist in Combating the Opioid Crisis: An Update.","authors":"Lucas Kosobuski,&nbsp;Carolyn O'Donnell,&nbsp;Cynthia P Koh-Knox Sharp,&nbsp;Nathaniel Chen,&nbsp;Laura Palombi","doi":"10.2147/SAR.S351096","DOIUrl":"https://doi.org/10.2147/SAR.S351096","url":null,"abstract":"<p><strong>Introduction: </strong>The opioid overdose crisis has claimed hundreds of thousands of lives in the United States in the last decade, with overdose numbers continuing to climb. At the same time, the role of the pharmacist in combating the opioid crisis continues to evolve.</p><p><strong>Methods: </strong>A literature search was conducted in Ovid MEDLINE that incorporated both MeSH terms and keywords to describe two concepts: the opioid epidemic and pharmacists/pharmacies. The search was limited to articles published after 2010 through the end of 2021 and returned 196 articles that were analyzed thematically.</p><p><strong>Results: </strong>Thematic analysis revealed the following themes: prevention, interventions, public health role of the pharmacist, pharmacists in multiple roles, barriers, pharmacist and healthcare provider attitudes, educational initiatives for pharmacists and student pharmacists, and future research.</p><p><strong>Discussion: </strong>While a great deal of progress has been made in the role of the pharmacist in supporting individuals with opioid use disorder (OUD) in the last two decades, pharmacists must seek to invest time and resources into practices with a strong evidence base to better mitigate the growing, devastating impact of the opioid crisis. Pharmacists must be willing to embrace new and non-traditional roles in patient care, service and research, and seek to advance evidence-based knowledge and practice.</p><p><strong>Conclusion: </strong>Pharmacy practice has expanded greatly in the past decade with pharmacists taking on new and creative approaches to addressing the opioid crisis. Collaborative and interdisciplinary approaches to addressing the root causes of opioid misuse and opioid overdose are still desperately needed. These include attention to the critical roles of social determinants of health, stigma elimination, legislative advocacy for patients with OUD, and focused education for providers, pharmacists, and the community. Recognition and support of the value of collaboration to both improve public health and individual patient care, continued investments in pharmacy practice advancement in OUD treatment and harm reduction, and the creation of workflows and prescribing algorithms to assist in dosing medications to prevent withdrawal symptoms and achieve improved pain control are desperately needed.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/b7/sar-13-127.PMC9805704.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10855961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Substance Use in Pregnancy: Identifying Stigma and Improving Care. 妊娠期物质使用:识别污名并改善护理。
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2021-11-23 eCollection Date: 2021-01-01 DOI: 10.2147/SAR.S319180
Andrea Weber, Benjamin Miskle, Alison Lynch, Stephan Arndt, Laura Acion
{"title":"Substance Use in Pregnancy: Identifying Stigma and Improving Care.","authors":"Andrea Weber,&nbsp;Benjamin Miskle,&nbsp;Alison Lynch,&nbsp;Stephan Arndt,&nbsp;Laura Acion","doi":"10.2147/SAR.S319180","DOIUrl":"https://doi.org/10.2147/SAR.S319180","url":null,"abstract":"<p><p>This review examines the impact of stigma on pregnant people who use substances. Stigma towards people who use drugs is pervasive and negatively impacts the care of substance-using people by characterizing addiction as a weakness and fostering beliefs that undermine the personal resources needed to access treatment and recover from addiction, including self-efficacy, help seeking and belief that they deserve care. Stigma acts on multiple levels by blaming people for having a problem and then making it difficult for them to get help, but in spite of this, most pregnant people who use substances reduce or stop using when they learn they are pregnant. Language, beliefs about gender roles, and attitudes regarding fitness for parenting are social factors that can express and perpetuate stigma while facilitating punitive rather than therapeutic approaches. Because of stigmatizing attitudes that a person who uses substances is unfit to parent, pregnant people who use substances are at heightened risk of being screened for substance use, referred to child welfare services, and having their parental rights taken away; these outcomes are even more likely for people of color. Various treatment options can successfully support recovery in substance-using pregnant populations, but treatment is underutilized in all populations including pregnant people, and more knowledge is needed on how to sustain engagement in treatment and recovery activities. To combat stigma when working with substance-using pregnant people throughout the peripartum period, caregivers should utilize a trauma-informed approach that incorporates harm reduction and motivational interviewing with a focus on building trust, enhancing self-efficacy, and strengthening the personal skills and resources needed to optimize health of the parent-baby dyad.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/a0/sar-12-105.PMC8627324.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39769052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
Problems in Social Medicine Related to Alcohol and Deaths: Autopsy Cases in the Southern Part of Osaka City. 与酒精和死亡有关的社会医学问题:大阪市南部的尸检案例。
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2021-10-27 eCollection Date: 2021-01-01 DOI: 10.2147/SAR.S326020
Naoto Tani, Tomoya Ikeda, Tatsuya Hirokawa, Yayoi Aoki, Alissa Shida, Kei Ikeda, Fumiya Morioka, Takaki Ishikawa
{"title":"Problems in Social Medicine Related to Alcohol and Deaths: Autopsy Cases in the Southern Part of Osaka City.","authors":"Naoto Tani,&nbsp;Tomoya Ikeda,&nbsp;Tatsuya Hirokawa,&nbsp;Yayoi Aoki,&nbsp;Alissa Shida,&nbsp;Kei Ikeda,&nbsp;Fumiya Morioka,&nbsp;Takaki Ishikawa","doi":"10.2147/SAR.S326020","DOIUrl":"https://doi.org/10.2147/SAR.S326020","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to examine the social and medical background of alcohol dependence and to prevent the abuse of alcohol.</p><p><strong>Methods: </strong>Alcohol and deaths were retrospectively investigated based on the forensic postmortem data of 1694 decedents ≥20 years of age in 2008-2017. Of these, the 999 cases that could be tested for alcohol within 48 h of death were examined.</p><p><strong>Results: </strong>The alcohol-positive and alcohol-negative groups included 179 (17.9%) and 820 (82.1%) cases, respectively. In terms of medical issues, compared with the alcohol-negative group, men in the positive group were mostly in their 40s to 60s, whereas women's age peaked in the 70s. The causes of death included many blunt injuries in men, though there was no difference in women. Underlying diseases were more frequent in men than women, with many of them having heart or liver disease, and the percentage of cases with mental disorders was 16.8% in the alcohol-positive group. In 15 cases of the alcohol-positive group, phenothiazine and barbituric acids were detected in 53.3% and 46.7% of cases, respectively. The incidence of traffic accidents and homicides was higher in the alcohol-positive group than in the alcohol-negative group.</p><p><strong>Conclusion: </strong>Measures to address social issues based on risk factors for alcohol and deaths are required.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/5e/sar-12-89.PMC8558042.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39680444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Disability Status, Unemployment, and Alcohol-Related Liver Disease (ALD) Mortality: A Large Sample Individual Level Longitudinal Study. 残疾状况、失业和酒精相关性肝病(ALD)死亡率:一项大样本个体水平纵向研究。
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2021-10-19 eCollection Date: 2021-01-01 DOI: 10.2147/SAR.S334851
Augustine J Kposowa, Kevin Breault
{"title":"Disability Status, Unemployment, and Alcohol-Related Liver Disease (ALD) Mortality: A Large Sample Individual Level Longitudinal Study.","authors":"Augustine J Kposowa,&nbsp;Kevin Breault","doi":"10.2147/SAR.S334851","DOIUrl":"https://doi.org/10.2147/SAR.S334851","url":null,"abstract":"<p><strong>Purpose: </strong>Unlike previous research, we evaluate disability within expanded employment status factors and stratify gender, race and ethnicity in alcohol-related liver disease (ALD) mortality in a large sample individual level longitudinal study.</p><p><strong>Materials and methods: </strong>The National Longitudinal Mortality Study (NLMS) was used covering the period 1990-2011. Statistical analysis involved the use of proportional hazards regression on a sample of almost 1.4 million people aged 18 and older, of whom 2638 died of ALD by the end of the follow-up period.</p><p><strong>Results: </strong>With expanded employment status factors, disability (HR=3.76 [95%] CI 3.22, 4.39), unemployment (HR=1.90, CI 1.56, 2.31), and those not otherwise in the labor force (HR=2.31, CI 2.08, 2.56) were strongly related to ALD mortality compared to the employed. When stratified, gender, race, and ethnicity were not important modifiers in the relationships between disability, unemployment, those not in the labor force and subsequent ALD mortality. Consistent with other studies, males, minority status, living in a highly urban area, renting as opposed to owning a home, lower educational attainment, marital statuses other than marriage, low income, and age were related to ALD mortality.</p><p><strong>Conclusion: </strong>In addition to unemployment which has been previously studied in a large longitudinal sample, disabled people who were unable to work and those not looking for work had a higher risk of ALD mortality. Alcohol consumption, abuse and morbidity in these populations are of considerable clinical concern.</p>","PeriodicalId":22060,"journal":{"name":"Substance Abuse and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4d/99/sar-12-81.PMC8541791.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39560475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Prevalence of Cigarette Smoking and Associated Factors Among Adolescents in Eastern Ethiopia, 2020. 2020年埃塞俄比亚东部青少年吸烟率及相关因素
IF 1.8
Substance Abuse and Rehabilitation Pub Date : 2021-10-13 eCollection Date: 2021-01-01 DOI: 10.2147/SAR.S331349
Abdurahman Kedir Roble, Mohamed Omar Osman, Om Parkash Lathwal, Abdirashid Abdi Aden
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引用次数: 3
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