Stroke Research and Treatment最新文献

{"title":"Longitudinal Study on Low-Dose Aspirin versus Placebo Administration in Silent Brain Infarcts: The Silence Study.","authors":"Ilaria Maestrini,&nbsp;Marta Altieri,&nbsp;Laura Di Clemente,&nbsp;Edoardo Vicenzini,&nbsp;Patrizia Pantano,&nbsp;Eytan Raz,&nbsp;Mauro Silvestrini,&nbsp;Leandro Provinciali,&nbsp;Isabella Paolino,&nbsp;Carmine Marini,&nbsp;Matteo Di Giuseppe,&nbsp;Tommasina Russo,&nbsp;Francesco Federico,&nbsp;Cristiana Coppola,&nbsp;Maria Pia Prontera,&nbsp;Domenico Maria Mezzapesa,&nbsp;Vincenzo Lucivero,&nbsp;Lucilla Parnetti,&nbsp;Paola Sarchielli,&nbsp;Maria Peducci,&nbsp;Domenico Inzitari,&nbsp;Giovanna Carlucci,&nbsp;Carlo Serrati,&nbsp;Carla Zat,&nbsp;Anna Cavallini,&nbsp;Alessandra Persico,&nbsp;Giuseppe Micieli,&nbsp;Stefano Bastianello,&nbsp;Vittorio Di Piero","doi":"10.1155/2018/7532403","DOIUrl":"https://doi.org/10.1155/2018/7532403","url":null,"abstract":"<p><strong>Background: </strong>We investigated low-dose aspirin (ASA) efficacy and safety in subjects with silent brain infarcts (SBIs) in preventing new cerebrovascular (CVD) events as well as cognitive impairment.</p><p><strong>Methods: </strong>We included subjects aged ≥45 years, with at least one SBI and no previous CVD. Subjects were followed up to 4 years assessing CVD and SBI incidence as primary endpoint and as secondary endpoints: (a) cardiovascular and adverse events and (b) cognitive impairment.</p><p><strong>Results: </strong>Thirty-six subjects received ASA while 47 were untreated. Primary endpoint occurred in 9 controls (19.1%) versus 2 (5.6%) in the ASA group (p=0.10). Secondary endpoints did not differ in the two groups. Only baseline leukoaraiosis predicts primary [OR 5.4 (95%CI 1.3-22.9, p=0.022)] and secondary endpoint-a [3.2 (95%CI 1.1-9.6, p=0.040)] occurrence.</p><p><strong>Conclusions: </strong>These data show an increase of new CVD events in the untreated group. Despite the study limitations, SBI seems to be a negative prognostic factor and ASA preventive treatment might improve SBI prognosis. <b>EU Clinical trial</b> is registered with EudraCT Number: 2005-000996-16; Sponsor Protocol Number: 694/30.06.04.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"7532403"},"PeriodicalIF":1.5,"publicationDate":"2018-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/7532403","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36653143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stroke Outcome and Determinants among Patients with and without Diabetes in a Tertiary Hospital in Ghana.","authors":"Josephine Akpalu, Alfred E Yawson, Foster Osei-Poku, Yacoba Atiase, Ernest Yorke, Patrick Adjei, Kodwo Nkromah, Albert Akpalu","doi":"10.1155/2018/7521351","DOIUrl":"10.1155/2018/7521351","url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus, a well-established independent risk factor for stroke, has varied association with stroke outcome from previous studies. This study investigated stroke outcome and determinants among patients with and without diabetes in a tertiary hospital in Ghana.</p><p><strong>Methods: </strong>A prospective study conducted among stroke patients with and without diabetes admitted in a Ghanaian tertiary hospital. Baseline clinical and biochemical data were documented. Functional stroke outcome was evaluated at 1, 3, and 6 months after stroke using the modified Rankin Scale.</p><p><strong>Results: </strong>Number of participants enrolled were 326 and 105 (32.20%) had diabetes. Higher proportions of diabetes patients had poor functional stroke outcome at 1, 3, and 6 months (79%, 75.23%, 73.33%) compared with those without diabetes (70.13%, 65.16, 61.99) (p>0.05). Stroke patients with diabetes had lower survival compared with those without diabetes (p=0.0745). Mortality at 6 months was more likely among ischaemic stroke patients with diabetes compared with those without diabetes (Odds Ratio 2.037; CI: 1.058-3.923). Determinants of poor functional stroke outcome for diabetes patients were older age (Adjusted Odds Ratio (AOR)-1.07; CI-1.03-1.12), female gender (AOR-3.74; CI-1.26-12.65), and pneumonia (AOR-11.32; CI-1.93-220.05) whereas the determinants for those without diabetes were unemployment (AOR-4.19; CI-1.24-19.50), speech abnormalities (AOR-1.99; CI1.08-3.73), and pneumonia (AOR-4.05; CI-1.83-9.77). High fasting plasma glucose (HR-1.15; CI-1.07-1.23), elevated temperature (HR-1.41; CI-1.11-1.79), and pneumonia (HR-2.25; CI-1.44-3.50) were determinants of low survival among all stroke patients.</p><p><strong>Conclusion: </strong>Trends towards poorer functional outcome and reduced survival were found among Ghanaian stroke patients with diabetes compared with those without diabetes. Older age, female gender, pneumonia, elevated temperature, and fasting plasma glucose were determinants of adverse outcome in stroke patients with diabetes.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"7521351"},"PeriodicalIF":1.5,"publicationDate":"2018-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36568108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment Outcomes and Associated Factors among Hospitalized Stroke Patients at Shashemene Referral Hospital, Ethiopia.","authors":"Tegegne Gobezie Temesgen,&nbsp;Berhanu Teshome,&nbsp;Peter Njogu","doi":"10.1155/2018/8079578","DOIUrl":"https://doi.org/10.1155/2018/8079578","url":null,"abstract":"<p><strong>Background: </strong>The 2013 Global Burden of Disease report indicated that 80% of stroke deaths occur in low- and middle-income regions. Although stroke has been consistently reported as one of the three leading causes of morbidity and mortality in the past years in Ethiopia, there is a paucity of data regarding treatment outcomes of stroke if sufficient. Hence, the present study aimed to assess patterns of treatment outcomes and associated factors among hospitalized stroke patients at Shashemene Referral Hospital.</p><p><strong>Methods: </strong>A retrospective cross-sectional study was conducted at the medical ward of Shashemene Referral Hospital. A total of 73 hospitalized stroke patients during the period 2012-2017 were included in the study. Demographic characteristics, risk factors, and stroke types and their hospital outcomes were reviewed from the medical records of the patients. The data were entered and analyzed using SPSS version 16.0. Descriptive statistics such as percent and frequency were used to summarize patients' characteristics. Binary logistic regression was used to investigate the potential predictors of treatment outcome. A p-value ≤0.05 was considered statistically significant.</p><p><strong>Result: </strong>Ischemic stroke was the most common type of stroke (65.8%) diagnosed in our setting. Hypertension (52.05%) was the common comorbid condition. More than half (54.79%) of the stroke patients improved on treatment. Dyslipidemics were prescribed to 68.49% of patients and the most popular antiplatelet was aspirin, which was prescribed to 61.64% of the study participants. Age, sex, type of stroke, and type of comorbidity were not significant factors of stroke treatment outcome.</p><p><strong>Conclusion: </strong>Ischemic stroke was the most common type of stroke diagnosed among the study participants while aspirin and statins were the most frequently used drugs in the management of stroke. Approximately 50% of hospitalized stroke patients had good treatment outcome and none of the investigated variables were significantly associated with the treatment outcomes.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"8079578"},"PeriodicalIF":1.5,"publicationDate":"2018-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/8079578","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36504091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the Joint Effect of Obesity and Diabetes on All-Cause Mortality and Cardiovascular-Related Mortality following an Ischemic Stroke.","authors":"Colleen Bauza,&nbsp;Renee' Martin,&nbsp;Sharon D Yeatts,&nbsp;Keith Borg,&nbsp;Gayenell Magwood,&nbsp;Anbesaw Selassie,&nbsp;Marvella E Ford","doi":"10.1155/2018/4812712","DOIUrl":"https://doi.org/10.1155/2018/4812712","url":null,"abstract":"<p><p>Although obesity and diabetes mellitus, or diabetes, are independently associated with mortality-related events (<i>e.g.,</i> all-cause mortality and cardiovascular-related mortality) following an ischemic stroke, little is known about the joint effect of obesity and diabetes on mortality-related events following an ischemic stroke. The aim of this study is to evaluate the joint effect of obesity and diabetes on mortality-related events in subjects with a recent ischemic stroke. Data from the multicenter Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial was analyzed for this study. The joint effect of obesity and diabetes on mortality-related events was estimated via Cox proportional hazards regression models. No difference in the hazard of all-cause mortality following an ischemic stroke was observed between obese subjects with diabetes and underweight/normal-weight subjects without diabetes. In contrast, obese subjects with diabetes had an increased hazard of cardiovascular-related mortality following an ischemic stroke compared with underweight/normal-weight subjects without diabetes. Additionally, there was evidence of an attributable proportion due to interaction as well as evidence of a highly statistically significant interaction on the multiplicative scale for cardiovascular-related mortality. In this clinical trial cohort of ischemic stroke survivors, obesity and diabetes synergistically interacted to increase the hazard of cardiovascular-related mortality.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"4812712"},"PeriodicalIF":1.5,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/4812712","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36455708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Chronic Anticoagulation Control in Patients with Intracranial Haemorrhage due to Vitamin K Antagonists.","authors":"Carlos Estevez-Fraga,&nbsp;Maria Molina-Sanchez,&nbsp;Rodrigo Alvarez-Velasco,&nbsp;Pablo Agüero-Rabes,&nbsp;Leticia Crespo-Araico,&nbsp;Elena Viedma-Guiard,&nbsp;Antonio Cruz-Culebras,&nbsp;Consuelo Matute,&nbsp;Rocio Vera,&nbsp;Alicia De Felipe-Mimbrera,&nbsp;Jaime Masjuan Vallejo","doi":"10.1155/2018/5613103","DOIUrl":"https://doi.org/10.1155/2018/5613103","url":null,"abstract":"<p><strong>Introduction: </strong>Patients treated with vitamin K antagonists (VKA) are at increased risk of intracranial haemorrhage (ICH). The purpose of our study was to determine the quality of previous anticoagulation control in patients with VKA-associated ICH.</p><p><strong>Materials and methods: </strong>We prospectively assessed every consecutive patient admitted to our stroke unit with VKA-associated ICH between 2013 and 2016. Demographic, clinical, and radiological variables, as well as consecutive international normalized ratios (INR) during 7 previous months, were extracted. Time in therapeutic range (TTR), time over range (TOR), time below range (TBR), and percentage of INR within range (PINRR) were calculated.</p><p><strong>Results and discussion: </strong>The study population comprised 53 patients. Mean age was 79 years; 42% were women. Forty-eight patients had atrial fibrillation (AF) and 5 mechanical prosthetic valves. Therapeutic or infratherapeutic INR on arrival was detected in 64.4% of patients (95% CI 2.7 to 3.2). TTR was 67.8% (95% CI: 60.2 to 75.6 %) and PINRR was 75% (95% CI: 49.9-100). TOR was 17.2% (95% CI: 10.4 to 23.9% ) and TBR was 17% (95% CI: 10.6 to 23.9%).</p><p><strong>Conclusion: </strong>VKA-associated ICH happens usually in the context of good chronic anticoagulation control. Newer risk assessment methods are required.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"5613103"},"PeriodicalIF":1.5,"publicationDate":"2018-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/5613103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36455709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographic Variations of Stroke Hospitalization across France: A Diachronic Cluster Analysis.","authors":"Yacine Lachkhem,&nbsp;Étienne Minvielle,&nbsp;Stéphane Rican","doi":"10.1155/2018/1897569","DOIUrl":"https://doi.org/10.1155/2018/1897569","url":null,"abstract":"<p><strong>Background: </strong>This study evaluates the clustering of hospitalization rates for stroke and compares this clustering with two different time intervals 2009-2010 and 2012-2013, corresponding to the beginning of the French National Stroke Plan 2010-2014. In addition, these data will be compared with the deployment of stroke units as well as socioeconomic and healthcare characteristics at zip code level.</p><p><strong>Methods: </strong>We used the PMSI data from 2009 to 2013, which lists all hospitalizations for stroke between 2009 and 2013, identified on the most detailed geographic scale allowed by this database. We identify statistically significant clusters with high or low rates in the zip code level using the Getis-Ord statistics. Each of the significant clusters is monitored over time and evaluated according to the nearest stroke unit distance and the socioeconomic profile.</p><p><strong>Results: </strong>We identified clusters of low and high rate of stroke hospitalization (23.7% of all geographic codes). Most of these clusters are maintained over time (81%) but we also observed clusters in transition. Geographic codes with persistent high rates of stroke hospitalizations were mainly rural (78% versus 17%, <i>P</i> < .0001) and had a least favorable socioeconomic and healthcare profile.</p><p><strong>Conclusion: </strong>Our study reveals that high-stroke hospitalization rates cluster remains the same during our study period. While access to the stroke unit has increased overall, it remains low for these clusters. The socioeconomic and healthcare profile of these clusters are poor but variations were observed. These results are valuable tools to implement more targeted strategies to improve stroke care accessibility and reduce geographic disparities.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"1897569"},"PeriodicalIF":1.5,"publicationDate":"2018-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/1897569","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36401641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke.","authors":"Payam Saadat,&nbsp;Alijan Ahmadi Ahangar,&nbsp;Mansor Babaei,&nbsp;Mandana Kalantar,&nbsp;Mohammad Ali Bayani,&nbsp;Hiva Barzegar,&nbsp;Hemmat Gholinia,&nbsp;Farbod Zahedi Tajrishi,&nbsp;Sekineh Faraji,&nbsp;Fatemeh Frajzadeh","doi":"10.1155/2018/6580178","DOIUrl":"https://doi.org/10.1155/2018/6580178","url":null,"abstract":"<p><strong>Introduction: </strong>Stroke is one of the most common neurological disorders with high mortality rates. A large financial burden is imposed on the families and health systems of countries in addition to the problems related to the disabilities caused by the disease for the patients. Extensive research is being conducted on the disease, including studies seeking possible relationships between some biomarkers such as uric acid and stroke.</p><p><strong>Methods: </strong>This descriptive-analytic cross-sectional study was conducted on 170 stroke patients at Babol Ayatollah Rohani Hospital during 2015-2016. Serum uric acid (SUA) levels were measured and recorded at admission time. Patients' demographic data as well as the stroke type and some of their risk factors were entered in a checklist. The data were analyzed by SPSS.v.23 using chi-square and logistic regression tests. <i>P</i> < 0.05 was considered as significant in all analyses.</p><p><strong>Results: </strong>Of the total 170 included patients, 57% had normal, 25% had low, and the remaining patients (18%) had high SUA levels. There was no significant difference in SUA levels in different types of stroke in both genders. Diabetic ischemic embolic patients had higher levels of SUA than diabetic ischemic thrombotic cases. Patients with low magnesium levels had higher rate of low levels of SUA in ischemic stroke.</p><p><strong>Conclusion: </strong>Serum uric acid levels are not associated with stroke types and gender. Diabetic embolic ischemic stroke cases had high SUA levels than thrombotic types and in ischemic stroke patients with low serum levels of magnesium, SUA levels were also lower.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"6580178"},"PeriodicalIF":1.5,"publicationDate":"2018-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/6580178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36354434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Upper Extremity Functions with a Single Session of Action-Observation-Execution and Accelerated Skill Acquisition Program in Subacute Stroke.","authors":"Shambhu Prasad Adhikari, Jarugool Tretriluxana, Pakaratee Chaiyawat, Chutima Jalayondeja","doi":"10.1155/2018/1490692","DOIUrl":"10.1155/2018/1490692","url":null,"abstract":"<p><strong>Background: </strong>Action-observation-execution (AOE) primes physical training. We examined the immediate effect of AOE with accelerated skill acquisition program (ASAP) on dexterity in subacute stroke.</p><p><strong>Methods: </strong>Twelve individuals from 1 to 6 months after stroke were allocated into two groups by matching age and side of stroke. After AOE of 30 minutes, the experimental group received ASAP for 60 minutes whereas the control group received dose-equivalent usual care. The movement time (MT) and functional ability (FA) of hand items of the Wolf motor function test (WMFT), hand functions and global recovery of stroke impact scale (SIS), and intrinsic motivation items of stroke rehabilitation motivation scale were assessed at baseline, after training, and during one-week follow-up. Data were analyzed within and between the groups.</p><p><strong>Results: </strong>AOE significantly decreased MT of flipping cards of WMFT and hand functions of SIS. Total MT was markedly reduced. AOE with ASAP demonstrated significant group-by-time interactions on MT of lifting pencil of WMFT, total MT, and global recovery. Grip strength, FA, and hand functions were significantly improved only in the experimental group. Both groups improved motivation significantly.</p><p><strong>Conclusions: </strong>The AOE with ASAP enhanced dexterity, which persisted for at least a week. This intervention might improve dexterity in subacute stroke.</p><p><strong>Trial registration number: </strong>This trial is registered with TCTR20161007001.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"1490692"},"PeriodicalIF":1.8,"publicationDate":"2018-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36312982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best Practices for The Interdisciplinary Rehabilitation Team: A Review of Mental Health Issues in Mild Stroke Survivors.","authors":"Alexandra L Terrill,&nbsp;Jaclyn K Schwartz,&nbsp;Samir R Belagaje","doi":"10.1155/2018/6187328","DOIUrl":"https://doi.org/10.1155/2018/6187328","url":null,"abstract":"<p><p>Individuals with mild strokes are generally considered fully functional and do not traditionally receive rehabilitation services. Because patients with mild stroke are assumed to have a good recovery, they may have deficits in other areas, including mental health, that are not addressed. As a result, patients with mild stroke are unable to meet quality of life standards. In addition, healthcare professionals are likely unaware of the potential mental health issues that may arise in mild stroke. To address this gap in knowledge, we review the evidence supporting mental health evaluation and intervention in mild stroke. Specifically, we review comorbid diagnoses including depression, anxiety, fatigue, and sleep disturbances and their potential effects on health and function. Finally, we conclude with general recommendations describing best practice derived from current evidence.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"6187328"},"PeriodicalIF":1.5,"publicationDate":"2018-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/6187328","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36285473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-Task Walking in Challenging Environments in People with Stroke: Cognitive-Motor Interference and Task Prioritization.","authors":"Celine Timmermans, Melvyn Roerdink, Thomas W J Janssen, Carel G M Meskers, Peter J Beek","doi":"10.1155/2018/7928597","DOIUrl":"10.1155/2018/7928597","url":null,"abstract":"<p><p>Cognitive-motor interference may contribute to the risk of falling in people with stroke, as may be the associated phenomenon of inappropriate task prioritization. Examining dual-task walking could provide valuable insights as to how to best evaluate and treat walking in people with stroke. This study aimed to examine the effect of different walking environments on cognitive-motor interference and task prioritization in dual-task walking in people with stroke. Using a repeated-measures design, cognitive-motor interference and task prioritization were assessed in 30 stroke survivors, while walking in a plain environment and in two challenging environments that were enriched with either stationary physical context or suddenly appearing projector-augmented context. All three walking environment conditions were performed with and without a concurrent serial-3 subtraction task. We found stronger cognitive-motor interference for the two challenging environments than for the plain walking environment. Cognitive-motor interference did not differ between challenging walking environments, but task prioritization did: motor performance was prioritized more in the environment with physical context than in the environment with projector-augmented context and vice versa for cognitive-task performance. In conclusion, walking environment strongly influenced cognitive-motor interference and task prioritization during dual-task walking in people with stroke.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2018 ","pages":"7928597"},"PeriodicalIF":1.5,"publicationDate":"2018-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36182567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}