Stroke Research and Treatment最新文献

{"title":"Evaluation of Contralateral Limb Cross Education and High-Frequency Repetitive Transcranial Magnetic Stimulation on Functional Indices of the Affected Upper Limb in Subacute Phase of Stroke","authors":"Katayoon Rezaei, Amin Kordi Yoosefinejad, Farzaneh Moslemi Haghighi, Mohsen Razeghi","doi":"10.1155/2023/4387667","DOIUrl":"https://doi.org/10.1155/2023/4387667","url":null,"abstract":"Background. Stroke is one of the causes of long-term morbidity. Despite rehabilitation strategies, most survivors live with motor deficits in the upper limbs. Objectives. The aim of the study was to compare the effect of contralateral cross education (CE) and high-frequency repetitive magnetic stimulation (HF-rTMS) on the function of upper extremity in subacute phase of stroke. Methods. Forty patients were randomly assigned into 4 groups. Group “A” received physical therapy (PT) for 10 sessions, 3 times per week. Group “B” received PT and HF-rTMS as follows: stimulation of 20 Hz for 5 s, intertrain interval for 50 s, 20 trains, 2000 pulses at 90% resting motor threshold, and conventional PT. Group “C” was treated with CE and PT. In group “D,” HF-rTMS, CE, and PT were administered. Results. Significant differences were found in the Fugl-Meyer scale between “A” and “C” (\u0000 \u0000 P\u0000 =\u0000 0.01\u0000 \u0000 ), “A” and “D” (\u0000 \u0000 P\u0000 =\u0000 0.02\u0000 \u0000 ), and “B” and “C” groups (\u0000 \u0000 P\u0000 =\u0000 0.01\u0000 \u0000 ). In the box-block test, there were significant differences between “A” and “B” (\u0000 \u0000 P\u0000 =\u0000 0.01\u0000 \u0000 ), “A” and “C” (\u0000 \u0000 P\u0000 <\u0000 0.001\u0000 \u0000 ), “B” and “D” (\u0000 \u0000 P\u0000 =\u0000 0.001\u0000 \u0000 ), and “B” and “C” groups (\u0000 \u0000 P\u0000 =\u0000 0.01\u0000 \u0000 ). Statistical differences were observed in grip strength between “A” and “B” (\u0000 \u0000 P\u0000 =\u0000 0.01\u0000 \u0000 ) and “A” and “C” groups (\u0000 \u0000 P\u0000 =\u0000 0.02\u0000 \u0000 ). Conclusions. It is suggested that clinicians select the therapeutic methods in line with their expected goal. When the goal is to improve upper extremity function, CE+PT could be more effective than HF-rTMS+PT. Also, CE+PT and HF-rTMS+PT were more effective than CE+HF-rTMS+PT at improving grip strength. Therefore, combining several methods would not always lead to better results.","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":" 1236","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138960073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"External Validation of SAFE Score to Predict Atrial Fibrillation Diagnosis after Ischemic Stroke: A Retrospective Multicenter Study","authors":"Miguel Quesada López, L. Amaya Pascasio, Sara Blanco Madera, Jorge Pagola, Diana Vidal de Francisco, Elena de Celis Ruiz, Inmaculada Villegas Rodríguez, Joaquín Carneado-Ruiz, J. García‐Carmona, Juan Manuel García Torrecillas, Ana López Ferreiro, Iker Elosua Bayes, Ricardo Jaime Rigual Bobillo, María Isabel López López, Íñigo Esain González, María Dolores Ortega Ortega, Marina Blanco Ruiz, Irene Pérez Ortega, Carlos Lázaro Hernández, Blanca Fuentes Gimeno, A. Arjona Padillo, Patricia Martínez Sánchez","doi":"10.1155/2023/6655772","DOIUrl":"https://doi.org/10.1155/2023/6655772","url":null,"abstract":"Introduction. The screening for atrial fibrillation (AF) scale (SAFE score) was recently developed to provide a prediction of the diagnosis of AF after an ischemic stroke. It includes 7 items: \u0000 \u0000 a\u0000 g\u0000 e\u0000 ≥\u0000 65\u0000 \u0000 years, bronchopathy, thyroid disease, cortical location of stroke, intracranial large vessel occlusion, NT-ProBNP ≥250 pg/mL, and left atrial enlargement. In the internal validation, a good performance was obtained, with an \u0000 \u0000 A\u0000 U\u0000 C\u0000 =\u0000 0.88\u0000 \u0000 (95% CI 0.84-0.91) and sensitivity and specificity of 83% and 80%, respectively, for \u0000 \u0000 s\u0000 c\u0000 o\u0000 r\u0000 e\u0000 s\u0000 ≥\u0000 5\u0000 \u0000 . The aim of this study is the external validation of the SAFE score in a multicenter cohort. Methods. A retrospective multicenter study, including consecutive patients with ischemic stroke or transient ischemic attack between 2020 and 2022 with at least 24 hours of cardiac monitoring. Patients with previous AF or AF diagnosed on admission ECG were excluded. Results. Overall, 395 patients were recruited for analysis. The SAFE score obtained an \u0000 \u0000 A\u0000 U\u0000 C\u0000 =\u0000 0.822\u0000 \u0000 (95% CI 0.778-0.866) with a sensitivity of 87.2%, a specificity of 65.4%, a positive predictive value of 44.1%, and a negative predictive value of 94.3% for a SAFE \u0000 \u0000 s\u0000 c\u0000 o\u0000 r\u0000 e\u0000 ≥\u0000 5\u0000 \u0000 , with no significant gender differences. Calibration analysis in the external cohort showed an absence of significant differences between the observed values and those predicted by the model (Hosmer-Lemeshow’s test 0.089). Conclusions. The SAFE score showed adequate discriminative ability and calibration, so its external validation is justified. Further validations in other external cohorts or specific subpopulations of stroke patients might be required.","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"119 5","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138590566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling Survival Time to Death among Stroke Patients at Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study.","authors":"Bikiltu Wakuma Negasa, Teramaj Wongel Wotale, Mesfin Esayas Lelisho, Legesse Kassa Debusho, Kibrealem Sisay, Wubishet Gezimu","doi":"10.1155/2023/1557133","DOIUrl":"10.1155/2023/1557133","url":null,"abstract":"<p><strong>Background: </strong>Stroke is a life-threatening condition that occurs due to impaired blood flow to brain tissues. Every year, about 15 million people worldwide suffer from a stroke, with five million of them suffering from some form of permanent physical disability. Globally, stroke is the second-leading cause of death following ischemic heart disease. It is a public health burden for both developed and developing nations, including Ethiopia.</p><p><strong>Objectives: </strong>This study is aimed at estimating the time to death among stroke patients at Jimma University Medical Center, Southwest Ethiopia.</p><p><strong>Methods: </strong>A facility-based retrospective cohort study was conducted among 432 patients. The data were collected from stroke patients under follow-up at Jimma University Medical Center from January 1, 2016, to January 30, 2019. A log-rank test was used to compare the survival experiences of different categories of patients. The Cox proportional hazard model and the accelerated failure time model were used to analyze the survival analysis of stroke patients using R software. An Akaike's information criterion was used to compare the fitted models.</p><p><strong>Results: </strong>Of the 432 stroke patients followed, 223 (51.6%) experienced the event of death. The median time to death among the patients was 15 days. According to the results of the Weibull accelerated failure time model, the age of patients, atrial fibrillation, alcohol consumption, types of stroke diagnosed, hypertension, and diabetes mellitus were found to be the significant prognostic factors that contribute to shorter survival times among stroke patients.</p><p><strong>Conclusion: </strong>The Weibull accelerated failure time model better described the time to death of the stroke patients' data set than other distributions used in this study. Patients' age, atrial fibrillation, alcohol consumption, being diagnosed with hemorrhagic types of stroke, having hypertension, and having diabetes mellitus were found to be factors shortening survival time to death for stroke patients. Hence, healthcare professionals need to thoroughly follow the patients who pass risk factors. Moreover, patients need to be educated about lifestyle modifications.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2023 ","pages":"1557133"},"PeriodicalIF":1.5,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10733594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138831586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Self-Directed Home Therapy Adherence Combined with TheraBracelet on Poststroke Hand Recovery: A Pilot Study.","authors":"Gabrielle Scronce, Viswanathan Ramakrishnan, Amanda A Vatinno, Na Jin Seo","doi":"10.1155/2023/3682898","DOIUrl":"10.1155/2023/3682898","url":null,"abstract":"<p><p>Hand impairment is a common consequence of stroke, resulting in long-term disability and reduced quality of life. Recovery may be augmented through self-directed therapy activities at home, complemented by the use of rehabilitation devices such as peripheral sensory stimulation. The objective of this study was to determine the effect of adherence to self-directed therapy and the use of TheraBracelet (subsensory random-frequency vibratory stimulation) on hand function for stroke survivors. In a double-blind, randomized controlled pilot trial, 12 chronic stroke survivors were assigned to a treatment or control group (<i>n</i> = 6/group). All participants were instructed to perform 200 repetitions of therapeutic hand tasks 5 days/week while wearing a wrist-worn device 8 hours/day for 4 weeks. The treatment group received TheraBracelet vibration from the device, while the control group received no vibration. Home task repetition adherence and device wear logs, as well as hand function assessment (Stroke Impact Scale Hand domain), were obtained weekly. Repetition adherence was comparable between groups but varied among participants. Participants wore the device to a greater extent than adhering to completing repetitions. A linear mixed model analysis showed a significant interaction between repetition and group (<i>p</i> = 0.01), with greater adherence resulting in greater hand function change for the treatment group (<i>r</i> = 0.94; <i>R</i> ² = 0.88), but not for the control group. Secondary analysis revealed that repetition adherence was greater for those with lower motor capacity and greater self-efficacy at baseline. This pilot study suggests that adherence to self-directed therapy at home combined with subsensory stimulation may affect recovery outcomes in stroke survivors. This trial is registered with NCT04026399.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2023 ","pages":"3682898"},"PeriodicalIF":1.8,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10017223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9377934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Burden and In-Hospital Mortality of Stroke Admissions at a Tertiary Level Hospital in Namibia: A Retrospective Cohort Study.","authors":"Saara Ndinelago Neshuku,&nbsp;Jessica Kirchner-Frankle,&nbsp;Maria Nangolo,&nbsp;Maria Moses,&nbsp;Chalese Olivia Einbeck,&nbsp;Percy Kumire,&nbsp;Vaja Zatjirua,&nbsp;Justor Banda","doi":"10.1155/2023/1978536","DOIUrl":"https://doi.org/10.1155/2023/1978536","url":null,"abstract":"<p><strong>Background: </strong>Despite stroke being a leading cause of morbidity and mortality globally, there is a dearth of information on the burden and outcomes of stroke in sub-Saharan Africa and Namibia in particular.</p><p><strong>Methods: </strong>A hospital-based, retrospective cohort study was conducted to analyse non-electronic medical records of all consecutive stroke patients who were admitted to one of the highest tertiary-level hospitals in Namibia for 12 months (2019-2020). The primary outcome of the study was to establish the in-hospital mortality, stroke subtypes, and associated complications.</p><p><strong>Results: </strong>In total, 220 patients were included in the study, their mean age was 53 (SD13.8) years, and 55.5% were males. 61.0% had an ischaemic stroke (IS), and 39.0% had a haemorrhagic stroke (HS). The mean age was significantly lower in patients with HS vs. IS (48.2 ± 12.2 vs. 56.1 ± 13.3, <i>p</i> < 0.001). Of the IS patients, the majority (29.0%) had total anterior circulation infarct (TACI), while in the HS group, 34.0% had basal ganglia haemorrhage with or without intraventricular extension. Hypertension (<i>p</i> = 0.015), dyslipidaemia (<i>p</i> = 0.001), alcohol consumption (<i>p</i> = 0.022), and other cardiovascular diseases (<i>p</i> = 0.007) were more prevalent in patients with IS compared to those with HS. The prevalence rate of intravenous thrombolysis was 2.2% in IS and use of intravenous antihypertensives in 25.9% of patients with HS than IS. The in-hospital mortality was 26.4% with complications such as raised ICP, aspiration pneumonia, hydrocephalus, and sepsis significantly high in those that died. Aspiration pneumonia (OR 2.79, 95% CI 1.63-4.76, <i>p</i> < 0.001) and increased ICP (OR 0.30, 95% CI 0.16-057, <i>p</i> < 0.001) were independent predictors of in-hospital mortality on the multivariate analysis.</p><p><strong>Conclusion: </strong>Our findings showed a younger mean age for stroke and mortality rate comparable to other low- to middle-income countries (LMICs). Hypertension and alcohol consumption were the main risk factors for both stroke subtypes, while aspiration pneumonia and raised intracranial pressure predicted in-hospital mortality.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2023 ","pages":"1978536"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10707567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conventional Mirror Therapy versus Immersive Virtual Reality Mirror Therapy: The Perceived Usability after Stroke.","authors":"Eliana da Silva Jaques,&nbsp;Anelise Ineu Figueiredo,&nbsp;Aniuska Schiavo,&nbsp;Bianca Pacheco Loss,&nbsp;Gabriel Hoff da Silveira,&nbsp;Vicenzo Abichequer Sangalli,&nbsp;Denizar Alberto da Silva Melo,&nbsp;Léder Leal Xavier,&nbsp;Márcio Sarroglia Pinho,&nbsp;Régis Gemerasca Mestriner","doi":"10.1155/2023/5080699","DOIUrl":"https://doi.org/10.1155/2023/5080699","url":null,"abstract":"<p><strong>Background: </strong>Stroke is a widespread and complex health issue, with many survivors requiring long-term rehabilitation due to upper-limb impairment. This study is aimed at comparing the perceived usability of two feedback-based stroke therapies: conventional mirror therapy (MT) and immersive virtual reality mirror therapy (VR).</p><p><strong>Methods: </strong>The study involved 45 participants, divided into three groups: the stroke survivors (<i>n</i> = 15), stroke-free older adults (<i>n</i> = 15), and young controls (<i>n</i> = 15). Participants performed two tasks using both MT and VR in a semirandom sequence. Usability instruments (SUS and NASA-TLX) were applied at the end of the activities, along with two experience-related questions.</p><p><strong>Results: </strong>The results indicated that both MT and VR had similar levels of perceived usability, with MT being more adaptable and causing less overall discomfort. Conversely, VR increased the perception of task difficulty and prevented participants from diverting their attention from the mirror-based feedback.</p><p><strong>Conclusion: </strong>While VR was found to be less comfortable than MT, both systems exhibited similar perceived usability. The comfort levels of the goggles may play a crucial role in determining the usability of VR for upper limb rehabilitation after stroke.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2023 ","pages":"5080699"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9575856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low Lymphocyte-to-Monocyte Ratio as a Possible Predictor of an Unfavourable Clinical Outcome in Patients with Acute Ischemic Stroke after Mechanical Thrombectomy.","authors":"Katarína Pinčáková, Georgi Krastev, Jozef Haring, Miroslav Mako, Viktória Mikulášková, Vladimír Bošák","doi":"10.1155/2022/9243080","DOIUrl":"10.1155/2022/9243080","url":null,"abstract":"<p><strong>Background: </strong>Although considerable progress has been made in the treatment of acute ischemic stroke (AIS), the clinical outcome of patients is still significantly influenced by the inflammatory response that follows stroke-induced brain injury. The aim of this study was to evaluate the potential use of complete blood count parameters, including indices and ratios, for predicting the clinical outcome in AIS patients undergoing mechanical thrombectomy (MT).</p><p><strong>Methods: </strong>This single-centre retrospective study is consisted of 179 patients. Patient data including demographic characteristics, risk factors, clinical data, laboratory parameters on admission, and clinical outcome were collected. Based on the clinical outcome assessed at 3 months after MT by the modified Rankin Scale (mRS), patients were divided into two groups: the favourable group (mRS 0-2) and unfavourable group (mRS 3-6). Stepwise multivariate logistic regression analysis was used to detect an independent predictor of the unfavourable clinical outcome.</p><p><strong>Results: </strong>An unfavourable clinical outcome was detected after 3 months in 101 patients (54.4%). Multivariate logistic regression analysis confirmed that the lymphocyte-to-monocyte ratio (LMR) was an independent predictor of unfavourable clinical outcome at 3 months (odds ratio = 0.761, 95% confidence interval 0.625-0.928, and <i>P</i> = 0.007). The value of 3.27 was chosen to be the optimal cut-off value of LMR. This value could predict the unfavourable clinical outcome with a 74.0% sensitivity and a 54.4% specificity.</p><p><strong>Conclusion: </strong>The LMR at the time of hospital admission is a predictor of an unfavourable clinical outcome at 3 months in AIS patients after MT.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":"2022 ","pages":"9243080"},"PeriodicalIF":1.8,"publicationDate":"2022-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10400575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for Hemorrhagic Stroke among Adults in the Democratic Republic of the Congo: A Hospital-Based Study in a Limited Resource Setting.","authors":"Jacques Mbaz Musung,&nbsp;Placide Kambola Kakoma,&nbsp;Marcellin Bugeme,&nbsp;Jeef Paul Munkemena Banze,&nbsp;Clarence Kaut Mukeng,&nbsp;Orly Ngungwa Muyumba,&nbsp;Berthe Mwad Kamalo,&nbsp;Harvey Kabulo Kapya,&nbsp;Ghyslain Lambo Ngongo,&nbsp;Laurent Kitwa,&nbsp;Evariste Tshibind Yav,&nbsp;Olivier Mukuku,&nbsp;Emmanuel Kiyana Muyumba","doi":"10.1155/2022/7840921","DOIUrl":"https://doi.org/10.1155/2022/7840921","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of stroke is increasing in sub-Saharan Africa. The scarcity of hospital-based stroke data in Lubumbashi (in the Democratic Republic of the Congo) led to the study, which was designed to describe the epidemiology of stroke and identify risk factors associated with hemorrhagic stroke among adult patients in Lubumbashi.</p><p><strong>Methods: </strong>This was a cross-sectional study of 158 adult patients admitted for stroke in the internal medicine department of Lubumbashi University Clinics from January 2018 to December 2020. Sociodemographic and clinical features, cardiovascular risk factors, and hospital mortality were collected. A logistic regression has determined the risk of developing a hemorrhagic stroke.</p><p><strong>Results: </strong>Of 9,919 hospitalized patients, 158 had a stroke with a hospital prevalence of 1.6%; 86 (54.4%) patients had a hemorrhagic stroke while 72 (45.6%) had an ischemic stroke. Of which 41.1% (65/158) were women. The mean age was 60.8 ± 13.3 years. Main clinical signs were hemiplegia (63.3%), headache (48.7%), speech disorders (38.6%), and dizziness (38.6%). Hypertension (82.9%) and hyperglycemia (53.2%) were the most common risk factors. Inhospital mortality was 22.8%. After logistic regression, independent predictors for developing hemorrhagic stroke were hypertension (aOR = 8.19; 95% CI: 2.72-24.66; <i>p</i> < 0.0001) and atrial fibrillation (aOR = 4.89; 95% CI: 1.41-16.89; <i>p</i> = 0.012).</p><p><strong>Conclusion: </strong>This study highlights the high stroke mortality in a resource-limited hospital and the burden of hypertension in the development of hemorrhagic stroke. It illustrates the need to establish stroke care setting to improve the quality of stroke care.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":" ","pages":"7840921"},"PeriodicalIF":1.5,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40707795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technology-Dependent Rehabilitation Involving Action Observation and Movement Imagery for Adults with Stroke: Can It Work? Feasibility of Self-Led Therapy for Upper Limb Rehabilitation after Stroke.","authors":"Sheree A McCormick,&nbsp;Christopher Ireland,&nbsp;Abebaw M Yohannes,&nbsp;Paul S Holmes","doi":"10.1155/2022/8185893","DOIUrl":"https://doi.org/10.1155/2022/8185893","url":null,"abstract":"<p><strong>Background: </strong>Motor (re)learning via technology-dependent therapy has the potential to complement traditional therapies available to older adults living with stroke after hospital discharge and increase therapy dose. To date, little is known about the feasibility of technology-dependent therapy in a home setting for this population.</p><p><strong>Objective: </strong>To develop a technology-dependent therapy that provides mental and physical training for older adults with stroke and assess feasibility. Specifically we ask, \"Can it work\"?</p><p><strong>Design: </strong>Single group repeated measures.</p><p><strong>Methods: </strong>13 participants, aged 18 years and over, were recruited over a six-month period. All participants had mild upper limb impairment following a stoke and were no longer receiving intensive rehabilitation. All participants received 18 days of technology-dependent therapy in their own home. Information was gathered on recruitment and retention, usability, and suitability of outcome measures.</p><p><strong>Results: </strong>11 participants completed the study. The recruitment rate (number recruited/number canvassed; 10.7%) suggests 1907 participants would need to be canvassed to recruit the necessary sample size (<i>n</i> = 204) for a definitive trial designed to provide 90% power at 5% level of significance to detect a clinically meaningful difference of 5.7 points on the Action Research Arm Test. The usability of the application was rated as exceptional on the System Usability Scale. Effectiveness cannot be determined from this study; however, there was a trend for improvement in measures of upper limb function and emotional well-being. <i>Limitations</i>. The study was limited by a relatively small sample size and lack of control group.</p><p><strong>Conclusions: </strong>This study demonstrated proof of concept of a technology-dependent therapy for upper limb rehabilitation following stroke. The data suggest a definitive trial is feasible, additional strategies to improve recruitment should be considered. Outcome measures aligned with the residual motor function of participants are required.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":" ","pages":"8185893"},"PeriodicalIF":1.5,"publicationDate":"2022-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40672515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Risk Score for Predicting Vascular Dementia after Ischemic Stroke in Thailand.","authors":"Pornpatr A Dharmasaroja,&nbsp;Thammanard Charernboon","doi":"10.1155/2022/1600444","DOIUrl":"https://doi.org/10.1155/2022/1600444","url":null,"abstract":"<p><strong>Background: </strong>Poststroke dementia is an important consequence of stroke and warrants early prevention, detection, and management. The objective of the study was to develop a simple clinical risk score for predicting risk of vascular dementia in patients with ischemic stroke.</p><p><strong>Methods: </strong>The design was a prospective cohort study with 177 ischemic stroke survivors. A standard stroke evaluation was performed at admission, and dementia evaluation was conducted at six months after stroke. The significant predictors were used to develop a risk score using a multivariable logistic regression model.</p><p><strong>Results: </strong>Six months after stroke, 27.1% of the patients were diagnosed with vascular dementia. Five predictors were used in the risk score: age, education, history of stroke, white matter hyperintensities, and stroke subtype. The risk score had an area under receiver operating characteristic curve (AuROC) of 0.76, 72.9% sensitivity, and 79.1% specificity in predicting risk of vascular dementia. The predicted probability of vascular dementia for each risk score point was also reported.</p><p><strong>Conclusion: </strong>The clinical risk score had an acceptable accuracy in predicting vascular dementia in ischemic stroke survivors. It can be used for identifying those who are at a high risk of developing vascular dementia.</p>","PeriodicalId":22054,"journal":{"name":"Stroke Research and Treatment","volume":" ","pages":"1600444"},"PeriodicalIF":1.5,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33489879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}