IF 4.9 2区医学

Sleep Pub Date : 2025-08-23 DOI: 10.1093/sleep/zsaf253

Ahmed S BaHammam

引用次数: 0

Resynchronizing the System: Adolescent Circadian Alignment as a Public Health Imperative. 重新同步系统：青少年昼夜节律调整作为公共卫生的当务之急。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-22 DOI: 10.1093/sleep/zsaf252

Alina Yang

引用次数: 0

DistillSleep: Real-Time, On-Device, Interpretable Sleep Staging from Single-Channel EEG. 蒸馏睡眠：实时、设备上、可解释的单通道脑电图睡眠分期。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-22 DOI: 10.1093/sleep/zsaf240

Keondo Park, Joopyo Hong, Wooseok Lee, Hyun-Woo Shin, Hyung-Sin Kim

{"title":"DistillSleep: Real-Time, On-Device, Interpretable Sleep Staging from Single-Channel EEG.","authors":"Keondo Park, Joopyo Hong, Wooseok Lee, Hyun-Woo Shin, Hyung-Sin Kim","doi":"10.1093/sleep/zsaf240","DOIUrl":"https://doi.org/10.1093/sleep/zsaf240","url":null,"abstract":"Study objectives: Polysomnography (PSG) is the current gold standard for sleep staging but requires laboratory equipment, multiple sensors, and labor-intensive manual scoring. We developed DistillSleep, a single-channel electroencephalogram (EEG) framework that delivers accurate, real-time, and interpretable sleep staging on resource-constrained devices.Methods: DistillSleep consists of (1) a high-capacity teacher model and (2) a 109 k-parameter student model designed for edge deployment. Both incorporate a Multi-Wavelength Pyramid module and Transformer-based architecture to capture intra- and inter-epoch features. Feature- and prediction-level knowledge distillation transfers the teacher's expertise to the student. Training and evaluation used >10 000 overnight recordings from six cohorts (SHHS1, PhysioNet 2018, DCSM, KISS, SleepEDF-78, ISRUC), following AASM guidelines. Performance was assessed with Macro-F1.Results: The teacher achieved state-of-the-art Macro-F1 scores (SHHS1 81.1%, PhysioNet 78.9%, DCSM 81.2%, KISS 80.0%) and provided frequency-resolved saliency maps, inter-epoch context and well-calibrated confidence (ECE 0.07). The student maintained competitive accuracy (up to 79.7% Macro-F1) while executing <10 ms per 30-second epoch on three embedded platforms (Raspberry Pi 4B, Jetson orin nano, Coral dev board), reducing computational load 115-fold versus the best prior method (SleePyCo). Interpretability was transferred intact to the student, offering clinicians frequency-band importance and inter-epoch context visualizations, and calibration was further improved by 2.7$times$.Conclusions: DistillSleep combines expert-level accuracy, millisecond-scale latency, and transparent decision logic in a single-channel EEG form factor. These capabilities pave the way for point-of-care diagnostics, same-night therapy titration, and large-scale home monitoring, expanding the reach of sleep medicine while retaining clinical trust.","PeriodicalId":22018,"journal":{"name":"Sleep","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Con: Sleep is a credit card, not a piggy bank. 弊：睡眠是一张信用卡，而不是存钱罐。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-21 DOI: 10.1093/sleep/zsaf251

Elizabeth B Klerman, Siobhan Banks, Till Roenneberg

引用次数: 0

Towards Long-Term Sleep Staging via Wearable Reflective Photoplethysmography. 通过穿戴式反射式光电脉搏波描记仪研究长期睡眠分期。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-21 DOI: 10.1093/sleep/zsaf246

Loris Constantin, Christian M Horvath, Florent Baty, Clémentine Aguet, Jérôme Van Zaen, Alia Lemkaddem, Loïc Jeanningros, Martin Proença, Xiaoli Yang, Kurt De Jaegere, Sebastian R Ott, João Jorge, Jean-Philippe Thiran, Theo A Meister, Rodrigo Soria, Hildegard Tanner, Emrush Rexhaj, Mathieu Lemay, Anne-Kathrin Brill, Fabian Braun

{"title":"Towards Long-Term Sleep Staging via Wearable Reflective Photoplethysmography.","authors":"Loris Constantin, Christian M Horvath, Florent Baty, Clémentine Aguet, Jérôme Van Zaen, Alia Lemkaddem, Loïc Jeanningros, Martin Proença, Xiaoli Yang, Kurt De Jaegere, Sebastian R Ott, João Jorge, Jean-Philippe Thiran, Theo A Meister, Rodrigo Soria, Hildegard Tanner, Emrush Rexhaj, Mathieu Lemay, Anne-Kathrin Brill, Fabian Braun","doi":"10.1093/sleep/zsaf246","DOIUrl":"https://doi.org/10.1093/sleep/zsaf246","url":null,"abstract":"Study objectives: Sleep staging is usually performed by manual scoring of polysomnography (PSG), which is expensive, laborious, and poorly scalable. We propose an alternative to PSG for ambulatory sleep staging using wearable photoplethysmography (PPG) recorded by a smartwatch and automated scoring.Methods: We previously trained a deep learning model on public datasets, with the specific purpose of performance generalizability to unseen datasets. In the present work, the model was assessed on two datasets of reflective PPG collected from wrist-worn devices: a) 68 overnight recordings and b) for the first time, 493 long-term recordings each lasting for 24 hours (170 subjects). Findings were compared either to a) expert scored sleep stages from PSG for the night recordings or b) actigraphy for the long-term recordings.Results: For the overnight recordings, the PPG-based model achieved 78.7% accuracy and a Cohen's κ of 0.68 on reflective PPG collected using wrist-worn devices compared to PSG using a 4-class setup (wake, N1 and N2 combined, N3 and REM) and a sleep/wake accuracy of 94.1%, with a Cohen's κ of 0.71. For the long-term recordings, a sleep/wake accuracy of 92.5% with a Cohen's κ of 0.80 was achieved when compared to a state-of-the-art actigraphy-based deep learning model.Conclusions: This state-of-the-art accuracy achieved on wrist-worn devices represents a significant advancement for home sleep monitoring and a valuable alternative to PSG-based sleep staging. Additionally, our model demonstrated promising results on long-term ambulatory recordings, paving the way towards continuous ambulatory monitoring of sleep stages and sleep-wake cycles.","PeriodicalId":22018,"journal":{"name":"Sleep","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring circadian and meal timing impacts on cortisol during simulated night shifts. 在模拟夜班期间探索昼夜节律和进餐时间对皮质醇的影响。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-21 DOI: 10.1093/sleep/zsaf249

Linda Grosser, Crystal Yates, Jillian Dorrian, Stephanie Centofanti, Leonie Heilbronn, Gary Wittert, David Kennaway, Alison M Coates, Charlotte C Gupta, Jacqueline M Stepien, Raymond W Matthews, Peter Catcheside, Siobhan Banks

{"title":"Exploring circadian and meal timing impacts on cortisol during simulated night shifts.","authors":"Linda Grosser, Crystal Yates, Jillian Dorrian, Stephanie Centofanti, Leonie Heilbronn, Gary Wittert, David Kennaway, Alison M Coates, Charlotte C Gupta, Jacqueline M Stepien, Raymond W Matthews, Peter Catcheside, Siobhan Banks","doi":"10.1093/sleep/zsaf249","DOIUrl":"https://doi.org/10.1093/sleep/zsaf249","url":null,"abstract":"Study objectives: Cortisol regulates various physiological systems and exhibits a circadian rhythm influenced by sleep-wake and light-dark cycles. The cumulative effects of consecutive night shifts and nighttime eating on cortisol dynamics are not well understood. This sub-study of a larger randomised controlled trial aimed to explore these relationships.Methods: This laboratory study employed a three-arm, controlled, parallel design. Fifty-two healthy non-shift workers (age 24.5 ± 4.8 years; BMI 24 ± 2.8 kg/m2) were assigned to one of three nighttime conditions: meal (n = 17), snack (n = 16), or no-meal (n = 19) at 00:30 h. Macronutrient content for the meal and snack was similar, comprising ~50% carbohydrate, 33% fat, 17% protein and 23 g fibre. Following an adaptation night, participants completed four simulated nightshifts, with cortisol levels measured ~hourly with additional measurements at 30, 60, and 120-minutes post-consumption of a meal, a snack or no-meal at 00:30 h. Mixed-effects ANOVAs analysed changes in cortisol levels resulting from nighttime eating and the effects of consecutive nightshifts.Results: Eating at night significantly influenced cortisol secretion, resulting in higher total cortisol output in the meal and snack conditions (AUCg p=.019 and p=.005), respectively, compared to the no-meal condition. Four consecutive nightshifts induced a temporal shift in the cortisol rhythm, with levels at 20:00 h on night-4 significantly elevated compared to night-1 (p=.007), and levels at 05:30 h significantly reduced on night-4 relative to night-1 (p=.003).Conclusions: Nightshifts and eating during the nightshift disrupt the cortisol rhythm. Repeated disruptions may have cumulative effects, potentially impacting cortisol-sensitive tissues and increasing risk of significant health disorders.","PeriodicalId":22018,"journal":{"name":"Sleep","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relaxation of social time pressure reveals tight coupling between daily sleep and eating behavior and extends the interval between last and first meal. 社会时间压力的放松揭示了日常睡眠和饮食行为之间的紧密耦合，延长了最后一餐和第一餐之间的间隔。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-20 DOI: 10.1093/sleep/zsaf247

Maria Korman, Chen Fleischmann, Vadim Tkachev, Cátia Reis, Yoko Komada, Denis Gubin, Vinod Kumar, Shingo Kitamura, Till Roenneberg

{"title":"Relaxation of social time pressure reveals tight coupling between daily sleep and eating behavior and extends the interval between last and first meal.","authors":"Maria Korman, Chen Fleischmann, Vadim Tkachev, Cátia Reis, Yoko Komada, Denis Gubin, Vinod Kumar, Shingo Kitamura, Till Roenneberg","doi":"10.1093/sleep/zsaf247","DOIUrl":"https://doi.org/10.1093/sleep/zsaf247","url":null,"abstract":"As a day-active species, humans abstain from some or all foods and beverages and rest at night. The modern social clock diverged from the natural light-dark clock with far-stretching consequences for both fasting/eating and sleep/wake daily cycles. During the COVID-19 pandemic, prolonged social restrictions (SR) offered a quasi-experimental protocol to directly test the impact of the relaxed social clock on eating and sleep behaviors and the coupling between them. Using data from a global survey of 5,747 adults (mean age 37.2±13.7, 67.1% females, 100% worked/studied), we show that relaxation of the social time pressure during social restrictions led, on average, to a 42 min increase in the habitual fasting duration (FD, interval between the last and the first meal) (from 12:16±2:09 to 12:57±2:04) and a 34 min delay in the fasting window. FD was extended by lengthening both the pre-sleep fasting and sleep durations. Pre-SR breakfast eaters delayed sleep and fasting, while breakfast skippers delayed sleep and advanced meals. Stopping alarm use on workdays was associated with a larger increase in FD. The correlations between chronotype, FD, and the mid-fasting time became more robust during SR. We conclude that relaxed social time pressure extends habitual fasting duration and promotes co-alignment of daily fasting and sleeping. Given the finding that the sleep-fasting phase relationship during social restrictions remained stable, we suggest that a 'daily sleep-fasting structure' may be a novel circadian marker quantifying the coupling between daily rhythms. These results may inform strategies of public circadian health management.","PeriodicalId":22018,"journal":{"name":"Sleep","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144969707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impacts of sleep loss on wake-active neurons. 睡眠不足对清醒活跃神经元的影响。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-20 DOI: 10.1093/sleep/zsaf248

Michele Bellesi, Kazue Semba, Sigird Veasey, Antoine Adamantidis, John Peever

引用次数: 0

The Environment Around the Sleeper is Changing: A Perspective. 睡眠者周围的环境正在改变：一个视角。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-19 DOI: 10.1093/sleep/zsaf235

Joon Chung, Mairead E Moloney, Azizi A Seixas, Chandra L Jackson

{"title":"The Environment Around the Sleeper is Changing: A Perspective.","authors":"Joon Chung, Mairead E Moloney, Azizi A Seixas, Chandra L Jackson","doi":"10.1093/sleep/zsaf235","DOIUrl":"10.1093/sleep/zsaf235","url":null,"abstract":"Sleep is shaped by a complex interplay of biological, behavioral, and environmental factors. While substantial attention has been paid to the first two factors, the role of environmental exposures, particularly weather patterns, ambient temperature variability, and other dynamic atmospheric conditions, remains relatively underexplored in sleep research. This gap is notable given the increasing availability of high-resolution environmental data and growing evidence that ambient conditions can influence circadian regulation, thermal comfort, and sleep continuity. This perspective paper reviews emerging evidence linking environmental factors to sleep patterns, highlighting both direct effects (e.g., thermal disruptions) and indirect pathways (e.g., displacement or stress from extreme weather events). Recent advances in environmental sensing, geospatial data, and real-time monitoring offer new opportunities to capture high-resolution environmental data relevant to sleep. This perspective highlights the need for data infrastructure capable of integrating these dynamic environmental inputs with sleep metrics from, for instance, wearables, surveys, and clinical records. We also examine the methodological and informatics challenges of integrating environmental data with sleep measures and suggest directions for future research. As environmental conditions evolve, understanding their influence on sleep holds promise for advancing both scientific knowledge and public health relevance, particularly in identifying affected populations, designing responsive interventions, and contextualizing sleep within broader ecological systems.","PeriodicalId":22018,"journal":{"name":"Sleep","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep-wake concordance in veteran-service dog dyads teaches us more about shared sleep experiences. 退伍军人服务犬的睡眠-觉醒一致性告诉我们更多关于共同睡眠经历的信息。

IF 4.9 2区医学

Sleep Pub Date : 2025-08-18 DOI: 10.1093/sleep/zsaf232

Heather E Gunn

引用次数: 0

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