IF 5.6 2区医学

Sleep Pub Date : 2024-10-05 DOI: 10.1093/sleep/zsae237

C Anderson

引用次数: 0

Bridging sleep with psychiatric disorders through genetics. 通过遗传学连接睡眠与精神疾病。

IF 5.6 2区医学

Sleep Pub Date : 2024-10-04 DOI: 10.1093/sleep/zsae235

Amber J Zimmerman, Struan F A Grant

引用次数: 0

Can't touch this: the emergence of contactless sleep technology. 触摸不到：非接触式睡眠技术的出现。

IF 5.6 2区医学

Sleep Pub Date : 2024-10-04 DOI: 10.1093/sleep/zsae207

Alexander Yoo, Ron C Anafi

引用次数: 0

Challenging the paradigm of alpha-synuclein's role in disease: can low levels also be bad for you? 挑战α-突触核蛋白在疾病中的作用模式：低水平的α-突触核蛋白也会对人体有害吗？

IF 5.6 2区医学

Sleep Pub Date : 2024-09-30 DOI: 10.1093/sleep/zsae229

Stefan Clemens, Tonya N Zeczycki

引用次数: 0

Machine learning identification of sleep EEG and EOG biomarkers for mortality risk. 通过机器学习识别睡眠脑电图和脑电图生物标志物，确定死亡风险。

IF 5.6 2区医学

Sleep Pub Date : 2024-09-30 DOI: 10.1093/sleep/zsae231

Wolfgang Ganglberger

引用次数: 0

Stress-induced Nocturnal Heart Rate Changes: A Potential Predictive Biomarker of PTSD Symptoms. 压力诱发的夜间心率变化：创伤后应激障碍症状的潜在预测性生物标志物

IF 5.6 2区医学

Sleep Pub Date : 2024-09-28 DOI: 10.1093/sleep/zsae227

Lior Kritzman, Matthew S Brock, Nava Levit-Binnun, Vincent Mysliwiec

引用次数: 0

Lending a Helping Hand: The complementary role of actigraphy in the assessment of Central Disorders of Hypersomnolence. 伸出援助之手：行动记录仪在评估中枢性嗜睡症中的辅助作用。

IF 5.6 2区医学

Sleep Pub Date : 2024-09-27 DOI: 10.1093/sleep/zsae228

Jesse D Cook, Cathy Goldstein, David T Plante

引用次数: 0

Sleep induced by mechanosensory stimulation provides cognitive and health benefits in Drosophila. 机械感官刺激诱导睡眠对果蝇的认知和健康有益

IF 5.6 2区医学

Sleep Pub Date : 2024-09-27 DOI: 10.1093/sleep/zsae226

Sho Inami, Kyunghee Koh

{"title":"Sleep induced by mechanosensory stimulation provides cognitive and health benefits in Drosophila.","authors":"Sho Inami, Kyunghee Koh","doi":"10.1093/sleep/zsae226","DOIUrl":"10.1093/sleep/zsae226","url":null,"abstract":"Study objectives: Sleep is a complex phenomenon regulated by various factors, including sensory input. Anecdotal observations have suggested that gentle rocking helps babies fall asleep, and experimental studies have verified that rocking promotes sleep in both humans and mice. Recent studies have expanded this understanding, demonstrating that gentle vibration also induces sleep in Drosophila. Natural sleep serves multiple functions, including learning and memory, synaptic downscaling, and reduction of harmful substances associated with neurodegenerative diseases. Here, we investigated whether vibration-induced sleep (VIS) provides similar cognitive and health benefits in Drosophila.Methods: We administered gentle vibration to flies that slept very little due to a forced activation of wake-promoting neurons and investigated how the vibration influenced learning and memory in the courtship conditioning paradigm. Additionally, we examined the effects of VIS on synaptic downscaling by counting synaptic varicosities of select neurons. Finally, we determined whether vibration could induce sleep in Drosophila models of Alzheimer's disease (AD) and suppress the accumulation of Amyloid β (Aβ) and Tubulin Associated Unit (TAU).Results: Vibration-induced sleep enhanced performance in a courtship conditioning paradigm and reduced the number of synaptic varicosities in select neurons. Moreover, vibration improved sleep in Drosophila models of AD, reducing Aβ and TAU levels.Conclusion: Mechanosensory stimulation offers a promising non-invasive avenue for enhancing sleep, potentially providing associated cognitive and health benefits.","PeriodicalId":22018,"journal":{"name":"Sleep","volume":null,"pages":null},"PeriodicalIF":5.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of night-to-night variations in objectively measured sleep on blood glucose in healthy university students. 客观测量的睡眠时间每晚变化对健康大学生血糖的影响。

IF 5.6 2区医学

Sleep Pub Date : 2024-09-26 DOI: 10.1093/sleep/zsae224

Alyssa S C Ng, E Shyong Tai, Michael W L Chee

{"title":"Effects of night-to-night variations in objectively measured sleep on blood glucose in healthy university students.","authors":"Alyssa S C Ng, E Shyong Tai, Michael W L Chee","doi":"10.1093/sleep/zsae224","DOIUrl":"10.1093/sleep/zsae224","url":null,"abstract":"Study objectives: We examined associations between daily variations in objectively measured sleep and blood glucose in a sample of non-diabetic young adults to complement laboratory studies on how sleep affects blood glucose levels.Methods: 119 university students underwent sleep measurement using an Oura Ring 2 and continuous glucose monitoring (CGM) for up to 14 days. In 69 individuals who consumed a standardised diet across the study, multilevel models examined associations between sleep duration, timing and efficiency and daily CGM profiles. Separately, in 58 individuals, multilevel models were used to evaluate postprandial glycaemic responses to a test meal challenge on 7 days. Participants also underwent oral glucose tolerance testing once after a night of ad libitum sleep, and again following a night of sleep restriction by 1-2 hours relative to that individual's habitual sleep duration. Between-condition glucose and insulin excursions, HOMA-IR and Matsuda index were compared.Results: Nocturnal sleep did not significantly influence following-day CGM profiles, postprandial glucose, or nocturnal mean glucose levels (all Ps>0.05). Longer sleep durations were associated with lower same-night glucose variability (all Ps<0.001). However, the range of variation of sugar levels was small and unlikely to be of functional significance. Considering naps in the analysis did not alter the findings. Sleep restriction by an average of 1.73 hours (SD=0.97) did not significantly impact excursions in glucose or insulin or insulin sensitivity the following morning (all Ps>0.05).Conclusions: Glucose handling in young, healthy adults may be more resilient to real-life fluctuations in sleep patterns than previously thought.","PeriodicalId":22018,"journal":{"name":"Sleep","volume":null,"pages":null},"PeriodicalIF":5.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep state-dependent development of resting state functional connectivity during the preterm period. 早产儿静息状态功能连接的发展与睡眠状态有关。

IF 5.6 2区医学

Sleep Pub Date : 2024-09-25 DOI: 10.1093/sleep/zsae225

Anna Shiraki, Hiroyuki Kidokoro, Hama Watanabe, Gentaro Taga, Takafumi Ushida, Hajime Narita, Takamasa Mitsumatsu, Sumire Kumai, Ryosuke Suzui, Fumi Sawamura, Yuji Ito, Hiroyuki Yamamoto, Tomohiko Nakata, Yoshiaki Sato, Masahiro Hayakawa, Yoshiyuki Takahashi, Jun Natsume

{"title":"Sleep state-dependent development of resting state functional connectivity during the preterm period.","authors":"Anna Shiraki, Hiroyuki Kidokoro, Hama Watanabe, Gentaro Taga, Takafumi Ushida, Hajime Narita, Takamasa Mitsumatsu, Sumire Kumai, Ryosuke Suzui, Fumi Sawamura, Yuji Ito, Hiroyuki Yamamoto, Tomohiko Nakata, Yoshiaki Sato, Masahiro Hayakawa, Yoshiyuki Takahashi, Jun Natsume","doi":"10.1093/sleep/zsae225","DOIUrl":"https://doi.org/10.1093/sleep/zsae225","url":null,"abstract":"Study objectives: The brains of preterm infants exhibit altered functional connectivity (FC) networks, but the potential variation in sleep states and the impact of breathing patterns on FC networks are unclear. This study explores the evolution of resting-state FC from preterm to term, focusing on breathing patterns and distinguishing between active sleep and quiet sleep.Methods: We recruited 63 preterm infants and 44 healthy-term infants and performed simultaneous electroencephalography and functional near-infrared spectroscopy. FC was calculated using oxy- and deoxyhemoglobin signals across eight channels. First, FC was compared between periodic breathing (PB) and non-PB segments. Then sleep state-dependent FC development was explored. FC was compared between active sleep and quiet sleep segments and between preterm infants at term and term-born infants in each sleep state. Finally, associations between FC at term, clinical characteristics, and neurodevelopmental outcomes in late infancy were assessed in preterm infants.Results: In total, 148 records from preterm infants and 44 from term-born infants were analyzed. PB inflated FC values. After excluding PB segments, FC was found to be elevated during active sleep compared to quiet sleep, particularly in connections involving occipital regions. Preterm infants had significantly higher FC in both sleep states compared to term-born infants. Furthermore, stronger FC in specific connections during active sleep at term was associated with unfavorable neurodevelopment in preterm infants.Conclusions: Sleep states play a critical role in FC development and preterm infants show observable changes in FC.","PeriodicalId":22018,"journal":{"name":"Sleep","volume":null,"pages":null},"PeriodicalIF":5.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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