Spinal cord最新文献_第8页

Obesity in wheelchair users with long-standing spinal cord injury: prevalence and associations with time since injury and physical activity 患有长期脊髓损伤的轮椅使用者的肥胖症：患病率以及与受伤后时间和体育锻炼的关系。

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-22 DOI: 10.1038/s41393-024-00995-6

Sonja de Groot, Jacinthe J. E. Adriaansen, Janneke M. Stolwijk-Swüste, Rutger Osterthun, Rita J. G. van den Berg-Emons, Marcel W. M. Post

{"title":"Obesity in wheelchair users with long-standing spinal cord injury: prevalence and associations with time since injury and physical activity","authors":"Sonja de Groot, Jacinthe J. E. Adriaansen, Janneke M. Stolwijk-Swüste, Rutger Osterthun, Rita J. G. van den Berg-Emons, Marcel W. M. Post","doi":"10.1038/s41393-024-00995-6","DOIUrl":"10.1038/s41393-024-00995-6","url":null,"abstract":"Secondary analysis of cross-sectional data from the ALLRISC cohort study. To investigate the prevalence of obesity and its association with time since injury (TSI) and physical activity (PA) in wheelchair users with long-standing (TSI > 10 years) spinal cord injury (SCI). Community, The Netherlands. Wheelchair users with SCI (N = 282) in TSI strata (10–19, 20–29, and ≥30 years) and divided in meeting SCI-specific exercise guidelines or not. Waist circumference (WC) and body mass index (BMI) were assessed. Participants were classified as being obese (WC > 102 cm for men, WC > 88 cm for women; BMI ≥ 25 kg/m2) or not. Logistic regression analyses were performed to investigate the associations between obesity and TSI and PA. Almost half of the participants (45–47%) were classified as obese. TSI was significantly associated with obesity, the odds of being obese were 1.4 higher when having a 10 years longer TSI. Furthermore, the odds of being obese were 2.0 lower for participants who were meeting the exercise guidelines. The prevalence of obesity is high in people with long-standing SCI. Those with a longer TSI and individuals who do not meet the exercise guidelines are more likely to be obese and need to be targeted for weight management interventions.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 7","pages":"378-386"},"PeriodicalIF":2.1,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140677615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Onabotulinum toxin A improves neurogenic detrusor overactivity following spinal cord injury: a systematic review and meta-analysis Onabotulinum toxin A 可改善脊髓损伤后的神经源性逼尿肌过度活动：系统综述与荟萃分析

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-18 DOI: 10.1038/s41393-024-00992-9

Saeed Vaheb, Yousef Mokary, Hamed Ghoshouni, Omid Mirmosayyeb, Elham Moases Ghaffary, Vahid Shaygannejad, Mohammad Yazdan Panah

{"title":"Onabotulinum toxin A improves neurogenic detrusor overactivity following spinal cord injury: a systematic review and meta-analysis","authors":"Saeed Vaheb, Yousef Mokary, Hamed Ghoshouni, Omid Mirmosayyeb, Elham Moases Ghaffary, Vahid Shaygannejad, Mohammad Yazdan Panah","doi":"10.1038/s41393-024-00992-9","DOIUrl":"10.1038/s41393-024-00992-9","url":null,"abstract":"Systematic review and meta-analysis. The current study aimed to assess the efficacy and safety of Onabotulinum toxin A (OBTX-A) treatment for neurogenic detrusor overactivity (NDO) in spinal cord injury (SCI) patients. Iran. All relevant articles of clinical trials and cohort studies indexed in PubMed/MEDLINE, Embase, Scopus, and Web of Science databases up to September 6, 2022, that addressed OBTX-A treatment for NDO following SCI were included. The quality of eligible studies was evaluated using Cochrane criteria. Also, the weighted mean difference (WMD) was measured with a random-effect model. Regarding the overall efficacy after OBTX-A treatment in the short term, volume per void (VV) (WMD = 118.8, 95% CI: 90.9–146.7, p < 0.01), incontinence-quality of life (IQoL) (WMD = 24.3, 95% CI: 15.8–32.8, p < 0.01), and maximum cystometric capacity (MCC) (WMD = 144.5, 95% CI: 132.3 to 156.7, p < 0.01) significantly increased, while maximum detrusor pressure during storage (MDP) (WMD = –30.5, 95% CI: –35.9 to –25.1, p < 0.01) showed a significant decrease. Furthermore, compared to the placebo group at the 200-unit dose, there was a significant increase in MCC (WMD = 113.5, 95% CI: 84.7 to 142.3, p < 0.01) and a significant decrease in MDP (WMD = −27.2, 95% CI: −39.2 to −15.1, p < 0.01). Urinary tract infection (UTI), hematuria, and autonomic dysreflexia were the most common side effects, occurring at rates of 29.6%, 14.8%, and 13.4%, respectively. Our findings highlighted the effectiveness and safety of OBTX-A as a promising treatment of NDO following SCI.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 6","pages":"285-294"},"PeriodicalIF":2.1,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140628311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of cervical spinal stenosis by automated 3D MRI segmentation of spinal cord and cerebrospinal fluid space 通过自动三维核磁共振成像分割脊髓和脑脊液空间，量化颈椎管狭窄程度

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-16 DOI: 10.1038/s41393-024-00993-8

Marc Hohenhaus, Jan-Helge Klingler, Christoph Scholz, Ralf Watzlawick, Ulrich Hubbe, Jürgen Beck, Marco Reisert, Urs Würtemberger, Nico Kremers, Katharina Wolf

{"title":"Quantification of cervical spinal stenosis by automated 3D MRI segmentation of spinal cord and cerebrospinal fluid space","authors":"Marc Hohenhaus, Jan-Helge Klingler, Christoph Scholz, Ralf Watzlawick, Ulrich Hubbe, Jürgen Beck, Marco Reisert, Urs Würtemberger, Nico Kremers, Katharina Wolf","doi":"10.1038/s41393-024-00993-8","DOIUrl":"10.1038/s41393-024-00993-8","url":null,"abstract":"Prospective diagnostic study. Anatomical evaluation and graduation of the severity of spinal stenosis is essential in degenerative cervical spine disease. In clinical practice, this is subjectively categorized on cervical MRI lacking an objective and reliable classification. We implemented a fully-automated quantification of spinal canal compromise through 3D T2-weighted MRI segmentation. Medical Center - University of Freiburg, Germany. Evaluation of 202 participants receiving 3D T2-weighted MRI of the cervical spine. Segments C2/3 to C6/7 were analyzed for spinal cord and cerebrospinal fluid space volume through a fully-automated segmentation based on a trained deep convolutional neural network. Spinal canal narrowing was characterized by relative values, across sever segments as adapted Maximal Canal Compromise (aMCC), and within the index segment as adapted Spinal Cord Occupation Ratio (aSCOR). Additionally, all segments were subjectively categorized by three observers as “no”, “relative” or “absolute” stenosis. Computed scores were applied on the subjective categorization. 798 (79.0%) segments were subjectively categorized as “no” stenosis, 85 (8.4%) as “relative” stenosis, and 127 (12.6%) as “absolute” stenosis. The calculated scores revealed significant differences between each category (p ≤ 0.001). Youden’s Index analysis of ROC curves revealed optimal cut-offs to distinguish between “no” and “relative” stenosis for aMCC = 1.18 and aSCOR = 36.9%, and between “relative” and “absolute” stenosis for aMCC = 1.54 and aSCOR = 49.3%. The presented fully-automated segmentation algorithm provides high diagnostic accuracy and objective classification of cervical spinal stenosis. The calculated cut-offs can be used for convenient radiological quantification of the severity of spinal canal compromise in clinical routine.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 7","pages":"371-377"},"PeriodicalIF":2.1,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-024-00993-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autonomic impairment is not explained by neurological level of injury or motor-sensory completeness 神经损伤程度或运动感觉完整性无法解释自主神经损伤

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-12 DOI: 10.1038/s41393-024-00994-7

Kathryn Burns, Ryan Solinsky

{"title":"Autonomic impairment is not explained by neurological level of injury or motor-sensory completeness","authors":"Kathryn Burns, Ryan Solinsky","doi":"10.1038/s41393-024-00994-7","DOIUrl":"10.1038/s41393-024-00994-7","url":null,"abstract":"Cross-sectional study. Determine how well common clinical assessments of level and completeness of injury are correlated with symptoms of autonomic blood pressure instability and secondary medical complications after spinal cord injury (SCI). Academic medical center, United States. Eighty-two individuals with (n = 48) and without (n = 34) SCI had symptoms of autonomic blood pressure instability quantified with the Autonomic Dysfunction Following SCI (ADFSCI) survey. Health histories quantified the secondary medical complications through number of urinary tract infections and hospitalizations in the past year, time to complete bowel program, and lifetime pressure injuries. Regression models were completed to identify strengths of associated correlations. ADFSCI scores were significantly higher in individuals with SCI than controls. Neurological level of injury and ASIA impairment scale were both minimally correlated to symptoms of autonomic blood pressure instability, accounting for only 11.5% of variability in regression models. Secondary medical complications had similar, minimal correlations to level and motor/sensory completeness of SCI (R2 = 0.07 and R2 = 0.03 respectively). Contrasting this, symptoms of blood pressure instability on ADFSCI far outperformed the common clinical motor/sensory bedside exam, with moderately strong correlations to the ranked number of secondary medical complications after SCI (R2 = 0.31). Neurological level of injury and motor/sensory completeness provided limited insights into which individuals with SCI would have blood pressure instability or secondary medical complications. Interestingly, symptoms of blood pressure instability outperform the clinical motor/sensory bedside exam, with higher correlations to secondary medical complications after SCI.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 7","pages":"367-370"},"PeriodicalIF":2.1,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of clinical and demographic predictors for understanding the cognitive impairment in Spinal Cord Injury (SCI) patients 了解脊髓损伤（SCI）患者认知障碍的临床和人口学预测因素的作用

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-12 DOI: 10.1038/s41393-024-00986-7

Ana Clara Portela Hara, Nicole C. Aching, Lucas M. Marques, Sara P. Barbosa, Daniel R. Souza, Felipe Fregni, Linamara R. Battistella, Marcel Simis

{"title":"The role of clinical and demographic predictors for understanding the cognitive impairment in Spinal Cord Injury (SCI) patients","authors":"Ana Clara Portela Hara, Nicole C. Aching, Lucas M. Marques, Sara P. Barbosa, Daniel R. Souza, Felipe Fregni, Linamara R. Battistella, Marcel Simis","doi":"10.1038/s41393-024-00986-7","DOIUrl":"10.1038/s41393-024-00986-7","url":null,"abstract":"Using a cross-sectional design, we extracted sociodemographic and clinical data from 488 Spinal Cord Injury (SCI) patients during their initial assessment before receiving intensive rehabilitation treatment. The primary objectives of this study were to ascertain the prevalence of cognitive impairment in the study sample and specify the key clinical and demographic predictors of cognitive functioning in SCI patients. Lucy Montoro Rehabilitation Institute (LMRI), University of Sao Paulo, Sao Paulo, Brazil. We utilized independent univariate and multivariate regression models with the Montreal Cognitive Assessment (MoCA) scale, adapted for individuals with visual impairment. Moreover, we consider scores from the execution tasks (visuospatial/executive) as the dependent variable. Our findings demonstrate that approximately 80% of the evaluated study sample exhibited cognitive impairment. Through the multivariate regression models, we show that several factors, including age, education, depression levels, and the use of analgesics and/or opioids, are significant predictors of total cognitive scores. These factors are independent of the clinical features associated with SCI, such as age, sex, education, and time since the injury. The results indicate a high prevalence of significant cognitive impairment within the sample, with age, education, depression levels, and the use of analgesics and/or opioids emerging as the primary predictors of total cognitive scores, independent of the clinical features correlated to SCI. These findings hold significant implications for both clinical research and practice, offering valuable guidance for comprehensive management throughout hospitalization and rehabilitation.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 6","pages":"336-342"},"PeriodicalIF":2.1,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient-reported outcomes in Primary Spinal Intradural Tumours: a systematic review 原发性脊柱硬膜外肿瘤的患者报告结果：系统性综述

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-08 DOI: 10.1038/s41393-024-00987-6

Ahmad M. S. Ali, Mohammad A. Mustafa, Omar M. E. Ali, Conor S. Gillespie, George M. Richardson, Simon Clark, Martin J. Wilby, Christopher P. Millward, Nisaharan Srikandarajah

{"title":"Patient-reported outcomes in Primary Spinal Intradural Tumours: a systematic review","authors":"Ahmad M. S. Ali, Mohammad A. Mustafa, Omar M. E. Ali, Conor S. Gillespie, George M. Richardson, Simon Clark, Martin J. Wilby, Christopher P. Millward, Nisaharan Srikandarajah","doi":"10.1038/s41393-024-00987-6","DOIUrl":"10.1038/s41393-024-00987-6","url":null,"abstract":"Systematic review. Primary Spinal Intradural Tumours (PSITs) are rare pathologies that can significantly impact quality of life. This study aimed to review patient reported outcomes (PROs) in PSITs. A systematic search of Pubmed and Embase was performed to identify studies measuring PROs in adults with PSITs. PRO results were categorised as relating to Global, Physical, Social, or Mental health. Outcomes were summarised descriptively. Following review of 2382 records, 11 studies were eligible for inclusion (737 patients). All studies assessed surgically treated patients. Schwannoma was the commonest pathology (n = 190). 7 studies measured PROs before and after surgery, the remainder assessed only post-operatively. For eight studies, PROs were obtained within 12 months of treatment. 21 PRO measurement tools were used across included studies, of which Euro-Qol-5D (n = 8) and the pain visual/numerical analogue scale (n = 5) were utilised most frequently. Although overall QoL is lower than healthy controls in PSITs, improvements following surgery were found in Extramedullary tumours (EMT) in overall physical, social, and mental health. Similar improvements were not significant across studies of Intramedullary tumours (IMT). Overall QoL and symptom burden was higher in IMT patients than in brain tumour patients. No studies evaluated the effect of chemotherapy or radiotherapy. Patients with PSITs suffer impaired PROs before and after surgery. This is particularly true for IMTs. PRO reporting in PSITs is hindered by a heterogeneity of reporting and varied measurement tools. This calls for the establishment of a standard set of PROs as well as the use of registries.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 6","pages":"275-284"},"PeriodicalIF":2.1,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-024-00987-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Duration of detrusor overactivity as an independent predictive factor of upper urinary tract deterioration in patients with traumatic spinal cord injury: results of a retrospective cohort study 作为创伤性脊髓损伤患者上尿路恶化独立预测因素的逼尿肌过度活动持续时间：一项回顾性队列研究的结果

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-04 DOI: 10.1038/s41393-024-00988-5

Pratchayapon Kammuang-lue, Sintip Pattanakuhar, Maysa Sermsuk, Chaisiri Angkurawaranon

{"title":"Duration of detrusor overactivity as an independent predictive factor of upper urinary tract deterioration in patients with traumatic spinal cord injury: results of a retrospective cohort study","authors":"Pratchayapon Kammuang-lue, Sintip Pattanakuhar, Maysa Sermsuk, Chaisiri Angkurawaranon","doi":"10.1038/s41393-024-00988-5","DOIUrl":"10.1038/s41393-024-00988-5","url":null,"abstract":"To determine whether duration of detrusor overactivity (DO) during a cystometric study is an independent predictive factor of upper urinary tract deterioration (UUTD) in patients with traumatic spinal cord injury (TSCI). Retrospective cohort study. A rehabilitation facility in Chiang Mai, Thailand. Data were obtained from medical records of patients who underwent cystometric evaluation at 6–12 months after TSCI. The independent predictor of interest is the duration of DO, which was evaluated by the DO/cystometry ratio (DOratio). Other conventional urodynamic parameters (maximum detrusor pressure, cystometric capacity, bladder compliance, and detrusor-sphincter dyssynergia) and clinical parameters (age, sex, level and severity of injury, comorbidities, bladder emptying method, and history of urinary tract infection) were determined. The outcome was UUTD, which is indicated by chronic kidney disease (GFR < 60 ml/min/1.73 m2), hydronephrosis, and/or vesicoureteral reflux. Multivariable Cox regression analysis was used to determine the independent associations between DOratio and UUTD by adjusting with all other parameters. Medical records of 194 patients with TSCI were included in the study. During a combined total of 1260 follow-up years of those patients, 34 UUTD events were identified, indicating an incidence rate of 27.0 cases per 1000 person-years. After adjusting for all other parameters, a high DOratio (≥0.33) was significantly associated with UUTD (hazard ratio = 3.00 [95% CI: 1.12–7.99], p = 0.025). DOratio may be an independent cystometric predictor of UUTD in patients with TSCI. However, further prospective study is needed prior to applying DOratio as a predictor of UUTD in clinical settings. There was no clinical trial registration since this study is not a clinical trial.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 6","pages":"328-335"},"PeriodicalIF":2.1,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity and reliability study of a novel surface electromyography sensor using a well-consolidated electromyography system in individuals with cervical spinal cord injury 新型表面肌电图传感器的有效性和可靠性研究--在颈部脊髓损伤患者中使用固化良好的肌电图系统

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-04 DOI: 10.1038/s41393-024-00981-y

Chandrasekaran Jayaraman, Chaithanya Krishna Mummidisetty, Arun Jayaraman, Kimberly Pfleeger, Michelle Jacobson, Melissa Ceruolo, Ellora Sen-Gupta, James Caccese, David Chen

{"title":"Validity and reliability study of a novel surface electromyography sensor using a well-consolidated electromyography system in individuals with cervical spinal cord injury","authors":"Chandrasekaran Jayaraman, Chaithanya Krishna Mummidisetty, Arun Jayaraman, Kimberly Pfleeger, Michelle Jacobson, Melissa Ceruolo, Ellora Sen-Gupta, James Caccese, David Chen","doi":"10.1038/s41393-024-00981-y","DOIUrl":"10.1038/s41393-024-00981-y","url":null,"abstract":"Non-interventional, cross-sectional pilot study. To establish the validity and reliability of the BioStamp nPoint biosensor (Medidata Solutions, New York, NY, USA [formerly MC10, Inc.]) for measuring electromyography in individuals with cervical spinal cord injury (SCI) by comparing the surface electromyography (sEMG) metrics with the Trigno wireless electromyography system (Delsys, Natick, MA, USA). Participants were recruited from the Shirley Ryan AbilityLab registry. Individuals aged 18–70 years with cervical SCI were evaluated with the two biosensors to capture activity on upper-extremity muscles during two study sessions conducted over 2 days (day 1–consent alone; day 2–two data collections in same session). Time and frequency metrics were captured, and signal-to-noise ratio was determined for each muscle group. Test-retest reliability was determined using Pearson’s correlation. Validation of the BioStamp nPoint system was based on Bland-Altmann analysis. Among the 11 participants, 30.8% had subacute cervical injury at C5–C6; 53.8% were injured within 1 year of the study. Results from the test-retest reliability assessment revealed that most Pearson’s correlations between the two sensory measurements were strong (≥0.50). The Bland-Altman analysis found values of the signal-to-noise ratio, frequency, and peak amplitude were within the level of agreement. Signal-to-noise ratios ranged from 7.06 to 22.1. In most instances, the performance of the BioStamp nPoint sensors was moderately to strongly correlated with that of the Trigno sensors in all muscle groups tested. The BioStamp nPoint system is a valid and reliable approach to assess sEMG measures in individuals with cervical SCI. The present study was supported by AbbVie Inc.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 6","pages":"320-327"},"PeriodicalIF":2.1,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-024-00981-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using the benefit-harm trade-off method to determine the smallest worthwhile effect of intensive motor training on strength for people with spinal cord injury 使用利弊权衡法确定强化运动训练对脊髓损伤患者力量的最小值得影响

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-03 DOI: 10.1038/s41393-024-00979-6

Keira E. Tranter, Joanne V. Glinsky, Marsha Ben, Helen Patterson, Lynn Blecher, Jackie Chu, Lisa A. Harvey

{"title":"Using the benefit-harm trade-off method to determine the smallest worthwhile effect of intensive motor training on strength for people with spinal cord injury","authors":"Keira E. Tranter, Joanne V. Glinsky, Marsha Ben, Helen Patterson, Lynn Blecher, Jackie Chu, Lisa A. Harvey","doi":"10.1038/s41393-024-00979-6","DOIUrl":"10.1038/s41393-024-00979-6","url":null,"abstract":"Interviews using the benefit-harm trade-off method and an online survey. To determine the smallest worthwhile effect (SWE) of motor training on strength for people with spinal cord injury (SCI). SCI units, Australia. Forty people with recent SCI who had participated in motor training as part of their rehabilitation program (patient participants) and 37 physiotherapists (physiotherapist participants) working in SCI were recruited. The patient participants underwent an iterative process using the benefit-harm trade-off method to determine the SWE of motor training on strength. The physiotherapist participants were given an online survey to determine the SWE for five different scenarios. Both groups considered the SWE of a physiotherapy intervention involving an additional 12 h of motor training for 10 weeks on top of usual care. They were required to estimate the smallest improvement in strength (points on the Total Motor Score of the International Standards for Neurological Classification of SCI) to justify the effort and associated costs, risks or inconveniences of the motor training. The median (interquartile range) smallest improvement in strength that patient and physiotherapist participants deemed worth the effort and associated costs, risks or inconveniences of the motor training was 3 (1–5) points, and 9 (7–13) points, respectively. People with recent SCI are willing to devote 12 h a week for 10 weeks to motor training in addition to their usual care to gain small changes in strength. Physiotherapists wanted to see greater improvements to justify the intervention.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 6","pages":"314-319"},"PeriodicalIF":2.1,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-024-00979-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140561733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A response to “Toward a better understanding and terminology of transcutaneous spinal cord stimulation” 对 "更好地理解和使用经皮脊髓刺激术术语 "的回应

IF 2.1 4区医学

Spinal cord Pub Date : 2024-04-03 DOI: 10.1038/s41393-024-00989-4

Auwal Bello Hassan, Auwal Abdullahi, Musa Sani Danazumi

引用次数: 0