Devon A Dobrosielski, Stephen J Ives, Karla A Kubitz, Hyunjeong Park, Christopher Papandreou, Susheel Patil
{"title":"The Effects of a Six-week Exercise Program on Heart Rate Variability in Adults with and Without Obstructive Sleep Apnea.","authors":"Devon A Dobrosielski, Stephen J Ives, Karla A Kubitz, Hyunjeong Park, Christopher Papandreou, Susheel Patil","doi":"10.1007/s41105-026-00666-4","DOIUrl":"10.1007/s41105-026-00666-4","url":null,"abstract":"<p><strong>Purpose: </strong>Exercise training improves heart rate variability (HRV) and is recommended as a behavioral treatment option for obese adults suffering from obstructive sleep apnea (OSA). We examined whether the effects of a supervised exercise program on HRV parameters differed according to OSA severity in obese adults.</p><p><strong>Methods: </strong>Obese (BMI> 33 kg*m<sup>-2</sup>) adults were evaluated for OSA using overnight polysomnography and subsequently classified as exhibiting no/mild OSA (AHI < 15 events*hour<sup>-1</sup>) or moderate/severe OSA (AHI > 15 events*hour<sup>-1</sup>). Cardiorespiratory fitness, body composition, and short-term heart rate variability (HRV) in frequency (VLF, LF, HF, LF/HF) and time (RMSSD, SDNN) domains were measured at baseline (Pre) and following a six-week (3 days/week) comprehensive exercise program (Post).</p><p><strong>Results: </strong>Twenty-seven adults (Age: 49 ± 9 years; W:14; M:13) with no/mild OSA and 29 adults (Age: 52 ± 9 years; W:15; M:14) with moderate/severe OSA completed all aspects of the trial. No significant differences in age, cardiorespiratory fitness, or HRV parameters were observed between groups at baseline. Across the sample, exercise training improved fitness (Pre: 30.5±6.4 vs. Post: 32.4±6.6 ml/kg/min, p<0.001), VLF% (p=0.015, η<sub>p</sub> <sup>2</sup>= 0.11), and HF% (p =0.016, η<sub>p</sub> <sup>2</sup>= 0.11). An interaction of OSA severity and exercise training was observed for SDNN (interaction p =0.01, η<sub>p</sub> <sup>2</sup>= 0.12), such that the no/mild OSA increased HRV, whereas the moderate to severe OSA decreased HRV.</p><p><strong>Conclusion: </strong>These data suggest that while six weeks of exercise led to parasympathetic improvement across the sample, it was insufficient to improve sympathetic HRV signal among overweight adults with moderate to severe OSA.</p>","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148449483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The association between nighttime sleep, daytime napping, and cardiovascular disease: a longitudinal analysis using CHARLS data.","authors":"Ze-Ying Wang, Peng Wang, Jie Cheng, Bao-Peng Liu, Cun-Xian Jia, Ming-Xiang Zhang","doi":"10.1007/s41105-026-00670-8","DOIUrl":"10.1007/s41105-026-00670-8","url":null,"abstract":"<p><strong>Purpose: </strong>Sleep patterns, including nighttime sleep, daytime napping, and their relationship with the risk of cardiovascular disease (CVD) remain unclear, particularly when psychological factors are considered. This study aims to investigate the influence of depressive symptoms on the association between sleep patterns and the incidence of CVD risk.</p><p><strong>Methods: </strong>A longitudinal analysis using CHARLS data included 4,912 participants, with a mean age of 68.13 (SD = 8.91). Sleep patterns and CVD were assessed by self-reported data. Multivariable logistic regression models were used to examine the associations. Stratified analyses based on depressive symptoms were conducted to assess potential effect modification. Mediation analyses were performed to explore potential pathways linking sleep patterns to incident CVD.</p><p><strong>Results: </strong>In all participants of fully adjusted model (Model 3), short nighttime sleep (< 7 h) was significantly associated with higher CVD risk (OR = 1.53, 95% CI: 1.15-2.03), while moderate daytime napping (31-60 min) demonstrated a protective effect (OR = 0.67, 95% CI: 0.46-0.97) and short daytime napping (≤ 30 min) lost its significance. Among participants with depressive symptoms, only short nighttime sleep remained significantly associated with elevated CVD risk. For participants without depressive symptoms, moderate daytime napping was protective against CVD occurrence. Mediation analysis confirmed depressive symptoms as a significant mediator in the pathway between nighttime sleep and CVD development.</p><p><strong>Conclusions: </strong>Divergent nighttime and daytime sleep durations exert differential effects on the incidence of CVD. Our findings have clarified that interventions specifically targeting different sleep durations in population with and without depressive symptoms are warranted to mitigate their elevated CVD risk.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at https://doi.org/10.1007/s41105-026-00670-8.</p>","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":"24 4","pages":"511-520"},"PeriodicalIF":2.0,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to \"Unmeasured confounding by mental health and chronic pain: a cautionary note on the causal interpretation of nonrestorative sleep and healthcare costs\".","authors":"Shota Matsunaga, Mitsuhiro Sado, Yoshitaka Kaneita, Norio Sasaki, Katsutoshi Tanaka, Kenichi Kuriyama","doi":"10.1007/s41105-026-00664-6","DOIUrl":"10.1007/s41105-026-00664-6","url":null,"abstract":"","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":"24 4","pages":"577"},"PeriodicalIF":2.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Velayudhan Mohan Kumar, Hruda Nanda Mallick, Kamalesh K Gulia
{"title":"Sleep laboratories in the age of artificial intelligence: toward predictive physiological phenotyping.","authors":"Velayudhan Mohan Kumar, Hruda Nanda Mallick, Kamalesh K Gulia","doi":"10.1007/s41105-026-00661-9","DOIUrl":"10.1007/s41105-026-00661-9","url":null,"abstract":"","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":"24 4","pages":"567-569"},"PeriodicalIF":2.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13619999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unmeasured confounding by mental health and chronic pain: a cautionary note on the causal interpretation of nonrestorative sleep and healthcare costs.","authors":"Minzhi Yang, Xiaojun Fei, Huan Du, Qin Liu","doi":"10.1007/s41105-026-00663-7","DOIUrl":"10.1007/s41105-026-00663-7","url":null,"abstract":"","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":"24 4","pages":"571-572"},"PeriodicalIF":2.0,"publicationDate":"2026-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of standardized and non-standardized Japanese translations of the Athens Insomnia Scale.","authors":"Yuta Takano, Isa Okajima, Hiroshi Kadotani","doi":"10.1007/s41105-026-00660-w","DOIUrl":"10.1007/s41105-026-00660-w","url":null,"abstract":"<p><strong>Purpose: </strong>Standardized and non-standardized Japanese translations of the Athens Insomnia Scale (AIS) have been used interchangeably. This study examined whether the non-standardized Japanese translation is equivalent to the standardized translation.</p><p><strong>Methods: </strong>A total of 1642 city government employees participated in this study. They completed both the standardized and non-standardized Japanese translations of the AIS.</p><p><strong>Results: </strong>Item scores (weighted kappa coefficients = 0.614-0.819), total scores (intraclass correlation coefficient = 0.883), and insomnia severity classifications (weighted kappa coefficient = 0.798) were statistically consistent between the translations.</p><p><strong>Conclusions: </strong>Our findings suggest that non-standardized translation can be used to assess insomnia symptoms.</p>","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":"24 4","pages":"555-559"},"PeriodicalIF":2.0,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of poor sleep patterns with all-cause mortality among participants with hypertension: a prospective cohort study.","authors":"Shiyue Cheng, Deng Hu","doi":"10.1007/s41105-026-00659-3","DOIUrl":"10.1007/s41105-026-00659-3","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of our study is to clarify the relationship between sleep duration, self-reported trouble sleeping, sleep disorders, and poor sleep patterns and all-cause mortality in participants with hypertension.</p><p><strong>Methods: </strong>We analyzed data from 11,359 hypertensive adults with complete follow-up. Sleep patterns were characterized based on sleep duration, self-reported trouble sleeping, and the presence of physician-diagnosed sleep disorders. Hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause mortality were estimated using multivariable Cox proportional hazards models.</p><p><strong>Results: </strong>Compared to healthy sleep patterns, poor sleep patterns were linked to higher all-cause mortality risk in hypertensive individuals (HR = 1.22 95% CI: 1.10-1.35). Specifically, long sleep duration (HR = 1.32 95% CI:1.18-1.49), sleep difficulties (HR = 1.11 95% CI: 1.02-1.20), and sleep disorders (HR = 1.25 95% CI: 1.11-1.42) increased mortality risk respectively. Among short sleepers, a duration of ≤ 4 h conferred a 24% greater risk relative to 7-9 h of sleep (HR = 1.24 95% CI: 1.07-1.45).</p><p><strong>Conclusion: </strong>The presence of poor sleep patterns, specifically long sleep duration, self-reported sleep troubles, or diagnosed sleep disorders, was associated with a higher risk of all-cause mortality among hypertensive participants. Compared with the hypertensive participants who slept for 7-9 h, those who slept for no more than 4 h had a higher risk of all-cause mortality.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at https://doi.org/10.1007/s41105-026-00659-3.</p>","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":"24 4","pages":"483-492"},"PeriodicalIF":2.0,"publicationDate":"2026-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blood pressure control by treatment of obstructive sleep apnea in patients with subacute ischemic stroke.","authors":"Takatoshi Kasai","doi":"10.1007/s41105-026-00658-4","DOIUrl":"10.1007/s41105-026-00658-4","url":null,"abstract":"","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":"24 3","pages":"303-304"},"PeriodicalIF":2.0,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13303992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Regina Grugel, Łukasz Pawelec, Aleksandra Karykowska
{"title":"The phenomenon of social jet lag in men with and without children.","authors":"Regina Grugel, Łukasz Pawelec, Aleksandra Karykowska","doi":"10.1007/s41105-026-00655-7","DOIUrl":"10.1007/s41105-026-00655-7","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate whether having children and engaging in caregiving responsibilities influence the regularity of sleep-wake rhythms in men, particularly in terms of reducing the phenomenon of social jet lag-the misalignment between biological and social time.</p><p><strong>Methods: </strong>This cross-sectional study was based on self-reported data collected online in the fall of 2023. Social jet lag was calculated as the difference between sleep timing on workdays and non-workdays. Statistical analyses included the Shapiro-Wilk test, Student's <i>t</i>-test, Mann-Whitney <i>U</i> test, chi-square test, and binary logistic regression. Group comparisons between four categories (fathers and childless men, with and without social jet lag) were performed using the Kruskal-Wallis test. The study sample consisted of 238 adult men (mean age = 28 years; SD = 9.05). The questionnaire included questions about the number and age of children, relationship status, sleep habits, alcohol use, and sleep medication intake. Individuals with irregular circadian patterns or shift work were excluded.</p><p><strong>Results: </strong>Social jet lag was significantly less prevalent among fathers compared to childless men. Having children was associated with a 70% lower likelihood of experiencing social jet lag. Fathers woke up earlier on both workdays and non-workdays and showed less variation in sleep timing between weekdays and weekends. No significant differences were observed in sleep duration on workdays or in overall average sleep time; however, fathers slept an average of 30 min less on days off.</p><p><strong>Conclusions: </strong>Fatherhood appears to promote a more regular sleep-wake schedule, which may reduce the incidence of social jet lag. While having children does not affect sleep duration during the workweek, it leads to less sleep extension on non-workdays. The child's routine may act as an external <i>zeitgeber</i>, helping stabilize the father's circadian rhythm.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at https://doi.org/10.1007/s41105-026-00655-7.</p>","PeriodicalId":21896,"journal":{"name":"Sleep and Biological Rhythms","volume":"24 4","pages":"467-472"},"PeriodicalIF":2.0,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}