Skinmed Pub Date : 2023-01-01

Ana Julia García-Malinis, Rocío Muñoz-Martínez, Alba Santamarina-Albertos, Pedro Jesús Agón-Banzo, Julia Barbado, Pilar Manchado-López

引用次数: 0

Pediatric Dermatology DDx Deck. 儿科皮肤科DDx甲板。

Skinmed Pub Date : 2023-01-01

Charles Cathcart, Michael Joseph Lavery

引用次数: 0

Old Habits Die Hard: The Need to Tackle Sunscreen Complacency. 旧习惯难改:需要解决防晒霜的自满情绪。

Skinmed Pub Date : 2023-01-01

Sophie Walter, Lawrence C Parish

引用次数: 0

Targetoid Lesions, but the Diagnosis Is Not Erythema Multiforme. 靶样病变，但诊断不是多形性红斑。

Skinmed Pub Date : 2023-01-01

Christopher D Markeson, Nicholas D Brownstone, Christina W Sun, Sylvia Hsu

引用次数: 0

New Non-Steroidal Topical Therapies for Inflammatory Dermatoses-Part 2: Tapinarof. 新的非甾体局部治疗炎症性皮肤病-第2部分:Tapinarof。

Skinmed Pub Date : 2023-01-01

Margaret DiRuggiero, Elizabeth Mancuso-Stewart, Douglas DiRuggiero, Matt Zirwas

{"title":"New Non-Steroidal Topical Therapies for Inflammatory Dermatoses-Part 2: Tapinarof.","authors":"Margaret DiRuggiero, Elizabeth Mancuso-Stewart, Douglas DiRuggiero, Matt Zirwas","doi":"","DOIUrl":"","url":null,"abstract":"Since its introduction in 1952, topical glucocorticosteroids remain the initial and long-term treatment option for various forms of inflammatory dermatitis. A number of non-steroidal topicals for treating inflammatory dermatoses have been developed in the recent decades (such as topical calcineurin inhibitors, vitamin D analogues, and phophodiesterase-4 inhibitors), but none had the combination of broad therapeutic range, relatively rapid onset of action, high tolerability, and wide-spread clinical success; this allowed topical glucocorticosteroids to remain the mainstay of therapy. This situation has shifted dramatically, with three non-steroidal new molecular entities, each with completely different mechanisms of action, receiving approval of the Food and Drug Administration (FDA) in the past year. Topical ruxolitinib, a Janus kinase (JAK) inhibitor, was approved by the FDA in September 2021 for atopic dermatitis, and was the subject of the first report in this review series. Subsequently, topical tapinarof, an aryl hydrocarbon receptor modulating agent, was approved by the FDA in May 2022 for treating plaque psoriasis, and is the focus of this present report. Finally and the most recently, topical roflumilast, a highly potent phosphodiesterase-4 inhibitor, received FDA approval in July 2022 for treating plaque psoriasis, and is reviewed in the third and final report in this series. In addition to their unique mechanisms of action and spectra of activity, each of these agents has unique clinical characteristics, including degree of efficacy, rapidity of onset of efficacy, potential remittive effects, and safety and tolerability profiles. In short, in this three-part series, we reviewed and summarized the data surrounding each agent, providing a comprehensive overview which would allow dermatologists to confidently and appropriately integrate them into treatment paradigms.","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 3","pages":"177-181"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10083891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Habif's Clinical Dermatology. 习惯临床皮肤病学。

Skinmed Pub Date : 2023-01-01

Michael Atkinson

引用次数: 0

Bariatric Surgery for Patients with Obesity May Also Help Their Psoriasis. 肥胖患者的减肥手术也可能帮助他们的牛皮癣。

Skinmed Pub Date : 2023-01-01

Alberto Conde-Taboada, Emily Mora, Álvaro Iglesias, Lucía Campos, Eduardo López-Bran

引用次数: 0

Acute Pustular Eruption of the Palms and Soles Following Streptococcal Pharyngitis. 链球菌性咽炎引起的手掌和脚底急性脓疱。

Skinmed Pub Date : 2023-01-01

Jacem Rouatbi, Amina Aounallah, Mouna Ben Hamouda, Zied Kenani, Badreddine Sriha, Colandane Belajouza, Mohamed Denguezli

引用次数: 0

The Efficacy of Cryotherapy and Zinc Gluconate in Management of Anogenital Warts: A Randomized Double-Blind, Split-Side, Placebo-Controlled Trial. 冷冻疗法和葡萄糖酸锌治疗肛门生殖器疣的疗效:一项随机双盲、裂侧、安慰剂对照试验。

Skinmed Pub Date : 2023-01-01

Mehdi Ghahartars, Akram Sahaf, Seyedeh Yasamin Parvar, Najmeh Ahramiyanpour

{"title":"The Efficacy of Cryotherapy and Zinc Gluconate in Management of Anogenital Warts: A Randomized Double-Blind, Split-Side, Placebo-Controlled Trial.","authors":"Mehdi Ghahartars, Akram Sahaf, Seyedeh Yasamin Parvar, Najmeh Ahramiyanpour","doi":"","DOIUrl":"","url":null,"abstract":"Anogenital warts are the most common sexually transmitted infection causing economic and psychosocial issues. Efficacy of zinc has been proved in treating nongenital warts, but its role in treating anogenital warts is not clear. This study was conducted to assess whether oral zinc gluconate in combination with cryotherapy effectively treated anogenital warts. A randomized double-blind, split-side, placebo-controlled trial was conducted on 50 patients suffering from genital warts. The patients were treated for 2 months with a combination of four sessions of cryotherapy and oral zinc gluconate versus placebos. Follow-up was performed at every 2 weeks based on the number of warts. The number of genital warts reduced significantly in both groups during treatment with cryotherapy, but no significant differences were observed between treatment with zinc and placebo. Patients in the zinc gluconate group reported significantly higher gastrointestinal adverse effects than those in the placebo group. This indicates that using oral zinc gluconate appeared to have no significant advantage over placebo in treating and reducing the number of genital warts; however, a longer duration of follow-up and pre-intervention serum level of zinc were necessary to evaluate the role of oral zinc therapy. (SKINmed. 2023;21:21-26).","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9209864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brooke-Spiegler Syndrome with Parotid Gland Involvement. 布鲁克-斯皮格勒综合征伴腮腺受累。

Skinmed Pub Date : 2023-01-01

Jessika Orellana Arnez Arandia, Taissa Canedo de Magalhães, Gabriella Mazzarone Gomes de Sá, Leonardo Hoehl Carneiro, Marcia Ramos-E-Silva

引用次数: 0

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