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Psoriasis Onset during Anti-TNF Treatment for Hidradenitis Suppurativa: Successful Remission of Both Conditions with Secukinumab. 抗肿瘤坏死因子治疗化脓性汗腺炎期间牛皮癣发作:Secukinumab成功缓解两种情况。
Skinmed Pub Date : 2023-01-01
Georgios Kontochristopoulos, Theodora Kanni, Ioannis Marnelakis, Efthymia Agiasofitou, Aikaterini Liakou, Dimitrios Rigopoulos
{"title":"Psoriasis Onset during Anti-TNF Treatment for Hidradenitis Suppurativa: Successful Remission of Both Conditions with Secukinumab.","authors":"Georgios Kontochristopoulos, Theodora Kanni, Ioannis Marnelakis, Efthymia Agiasofitou, Aikaterini Liakou, Dimitrios Rigopoulos","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 1","pages":"57-58"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9264153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of Safety, Efficacy, and Patient Counseling for Ruxolitinib in Treating Atopic Dermatitis. 鲁索利替尼治疗特应性皮炎的安全性、有效性和患者咨询综述。
Skinmed Pub Date : 2023-01-01
Elizabeth Mancuso-Stewart, Jaimie Rodger, Matthew Zirwas
{"title":"Overview of Safety, Efficacy, and Patient Counseling for Ruxolitinib in Treating Atopic Dermatitis.","authors":"Elizabeth Mancuso-Stewart,&nbsp;Jaimie Rodger,&nbsp;Matthew Zirwas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ruxolitinib, a Janus kinase (JAK) inhibitor, has been used orally for over a decade in the treatment of myelofibrosis. The immunosuppressive and anti-inflammatory properties of ruxolitinib have made it an attractive treatment option for several dermatologic conditions, such as atopic dermatitis, psoriasis, alopecia areata, and vitiligo. In October 2021, US Food and Drug Administration approved ruxolitinib as the first topical JAK inhibitor for treating atopic dermatitis. Recent studies have demonstrated its efficacy for both visible manifestations and itch of atopic dermatitis. These results indicate that topical ruxolitinib could be used as a long-term glucocorticoid for treating atopic dermatitis. While more studies are required to compare it to classic topical treatments of atopic dermatitis, topical ruxolitinib has a promising future in the field of dermatology. (<i>SKINmed</i>. 2023;21:40-43).</p>","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 1","pages":"40-43"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9209867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accessory Tragus Resembling a Hair Follicle Nevus. 类似于毛囊痣的附属耳屏。
Skinmed Pub Date : 2023-01-01
Solomon Geizhals, Cynthia M Magro, Shari R Lipner
{"title":"Accessory Tragus Resembling a Hair Follicle Nevus.","authors":"Solomon Geizhals,&nbsp;Cynthia M Magro,&nbsp;Shari R Lipner","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 1","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9264149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual Presentation of Non- Neoformans Cryptococcal Infection: Cutaneous Cryptococcosis Caused by Cryptococcus laurentii. 非新生隐球菌感染的不寻常表现:由劳伦隐球菌引起的皮肤隐球菌病。
Skinmed Pub Date : 2023-01-01
Khairuddin Djawad, Nugrah Santo, Safruddin Amin, Dirmawati Kadir, Nasrum Massi
{"title":"Unusual Presentation of Non- Neoformans Cryptococcal Infection: Cutaneous Cryptococcosis Caused by <i>Cryptococcus laurentii</i>.","authors":"Khairuddin Djawad,&nbsp;Nugrah Santo,&nbsp;Safruddin Amin,&nbsp;Dirmawati Kadir,&nbsp;Nasrum Massi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 1","pages":"51-52"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9264151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Verrucous Carcinoma Arising in an Extended Giant Condyloma Acuminatum. 扩大性巨大尖锐湿疣的疣状癌。
Skinmed Pub Date : 2023-01-01
Anissa Zaouak, Wissal Ebdelli, Takoua Bacha, Wafa Koubaa, Houda Hammami, Samy Fenniche
{"title":"Verrucous Carcinoma Arising in an Extended Giant Condyloma Acuminatum.","authors":"Anissa Zaouak,&nbsp;Wissal Ebdelli,&nbsp;Takoua Bacha,&nbsp;Wafa Koubaa,&nbsp;Houda Hammami,&nbsp;Samy Fenniche","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 43-year-old heterosexual Tunisian man presented to the dermatology department with complaints of a genital friable mass. He had a past medical history of chronic hepatitis B. He was married and had a history of multiple sexual partners. The lesion had been present for over 10 years and gradually increased in size, disfiguring his genitalia. It had a major impact on his quality of life, preventing sexual intercourse and resulting in poor personal hygiene. On physical examination, the vegetative lesion presented as a giant cauliflower-like tumor (Figure 1) with a foul smell. The tumor involved the left inguinal region, the suprapubic genitalia, and was encircling the entire penile shaft. He also had inguinal lymphadenopathies. Under local anesthesia, a skin biopsy of the vegetative tumor was performed and sent for histopathologic examination. It revealed an exophytic epithelial tumor with papillomatosis, marked acanthosis, and many koilocytes, especially in the superficial layers of the epidermis. These signs along with the preservation of regular cytology were consistent with the diagnosis of condyloma acuminatum (Figure 2a). The histologic examination also showed clusters of atypical keratinocytes with high mitotic activity and keratinization, suggesting nests of squamous cell carcinoma (SCC) (Figure 2b and 2c). DNA-polymerase chain reaction (PCR) marker for Human papilloma virus (HPV) stains 11 was positive. Serology for hepatitis C, HIV, and syphilis non-reactive. Computed tomography scan of the abdomen and pelvis showed inguinal lymphadenopathies. The patient was referred to the oncologist for radiotherapy to reduce the size of the tumor followed by surgery. (<i>SKINmed</i>. 2023;21:53-54).</p>","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 1","pages":"53-54"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9202996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Annular Lichenoid Dermatitis of Youth: Its Pathogenesis, Diagnosis, and Management. 青年环状苔藓样皮炎:发病机制、诊断和处理。
Skinmed Pub Date : 2023-01-01
Tara Bardawil, Samar Khalil, Mazen Kurban, Nourhane Nasser, Ossama Abbas
{"title":"Annular Lichenoid Dermatitis of Youth: Its Pathogenesis, Diagnosis, and Management.","authors":"Tara Bardawil,&nbsp;Samar Khalil,&nbsp;Mazen Kurban,&nbsp;Nourhane Nasser,&nbsp;Ossama Abbas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Annular lichenoid dermatitis of youth (ALDY) is a newly described controversial benign lichenoid inflammatory cutaneous disorder often characterized by annular patches with hypopigmented center and surrounding erythematous border. Primarily, it affects the trunk and groin of young patients. Since its first description in 2003, additional patients have been reported, leading to better characterization of the entity; nevertheless, the pathogenesis is still unclear, and several hypotheses have been provided about possible triggering or causative factors. It tends to follow a chronic course, with some lesions spontaneously remitting, while others may be persistent or recur post-treatment. No standard validated treatment has been indicated so far for this disorder. Commonly prescribed topical treatment includes corticosteroids and calcineurin inhibitors with variable response.</p>","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 2","pages":"72-81"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9791470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitiligo following the COVID-19 Vaccination and Infection. COVID-19疫苗接种和感染后的白癜风。
Skinmed Pub Date : 2023-01-01
Maxwell Green, Aileen Feschuk, Nadia Kashetsky, Howard I Maibach
{"title":"Vitiligo following the COVID-19 Vaccination and Infection.","authors":"Maxwell Green,&nbsp;Aileen Feschuk,&nbsp;Nadia Kashetsky,&nbsp;Howard I Maibach","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"21 3","pages":"213-216"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10532292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Presentation: Monkeypox. 病例介绍：猴痘
Skinmed Pub Date : 2022-12-20 eCollection Date: 2022-01-01
W Clark Lambert, Yolanda Riley, Roslyn Mandrique Banfiancila, Albert Alhatem
{"title":"Case Presentation: Monkeypox.","authors":"W Clark Lambert, Yolanda Riley, Roslyn Mandrique Banfiancila, Albert Alhatem","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Monkeypox is a rare viral disease that initially appeared in West and Central Africa, and is primarily transmitted to humans from animals. It moved to the United States in 2003, which was the first time the disease had left the African continent. It is still uncommon in the United States and elsewhere, although outbreaks have occurred, especially in gay communities,<sup>1-3</sup> causing it to be declared a health emergency in some areas. (<i>SKINmed</i>. 2022;20:410-411).</p>","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"20 6","pages":"410-411"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10466909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Monkeypox Outbreak 2022: Women and Children Patients. 2022 年猴痘疫情：妇女和儿童患者。
Skinmed Pub Date : 2022-10-31 eCollection Date: 2022-01-01
Leonard J Hoenig
{"title":"The Monkeypox Outbreak 2022: Women and Children Patients.","authors":"Leonard J Hoenig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Between January 1, 2022 and July 4, 2022, the World Health Organization (WHO) received 6,027 reports of laboratory-confirmed patients of monkeypox, predominantly men, that had occurred during a multi-country outbreak of the virus. During this period, 21 women and six children were reportedly infected with the monkeypox virus. Although the infected number of women and children was small, these data are worrisome, because young children and pregnant women are at increased risk of severe outcomes from monkeypox. One infant already has been hospitalized in intensive care in London, England. The WHO data regarding the 2022 monkeypox outbreak also indicate that 25 healthcare workers have been diagnosed with monkeypox, although it is still being investigated whether their infection was due to occupational exposure. Three deaths from monkeypox have been reported to WHO during this monkeypox outbreak. A special focus of this presentation is on the monkeypox infection involving women and children.</p>","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"20 5","pages":"334-335"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9287066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monkeypox Twitter Activity: Public Understanding of Transmission Dynamics. 猴痘推特活动：公众对传播动态的了解。
Skinmed Pub Date : 2022-10-31 eCollection Date: 2022-01-01
Jonathan Xu, Nicholas A Ross
{"title":"Monkeypox Twitter Activity: Public Understanding of Transmission Dynamics.","authors":"Jonathan Xu, Nicholas A Ross","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21891,"journal":{"name":"Skinmed","volume":"20 5","pages":"394-395"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9279905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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