Sexual Medicine最新文献

{"title":"Increased reproductive tract infections among secondary school girls during the COVID-19 pandemic: associations with pandemic-related stress, mental health, and domestic safety.","authors":"Supriya D Mehta, Debarghya Nandi, Fredrick Otieno, Garazi Zulaika, Elizabeth Nyothach, Walter Agingu, Runa Bhaumik, Linda Mason, Anna Maria van Eijk, Penelope A Phillips-Howard","doi":"10.1093/sexmed/qfae045","DOIUrl":"10.1093/sexmed/qfae045","url":null,"abstract":"<p><strong>Background: </strong>Kenya, like many countries, shuttered schools during COVID-19, with subsequent increases in poor mental health, sexual activity, and pregnancy.</p><p><strong>Aim: </strong>We sought to understand how the COVID-19 pandemic may mediate the risk of reproductive tract infections.</p><p><strong>Methods: </strong>We analyzed data from a cohort of 436 secondary schoolgirls in western Kenya. Baseline and 6-, 12-, and 18-month study visits occurred from April 2018 to December 2019 (pre-COVID-19), and 30-, 36-, and 48-month study visits occurred from September 2020 to July 2022 (COVID-19 period). Participants self-completed a survey for sociodemographics and sexual activity and provided self-collected vaginal swabs for bacterial vaginosis (BV) testing, with sexually transmitted infection (STI) testing at annual visits. We hypothesized that greater COVID-19-related stress would mediate risk via mental health, feeling safe inside the home, and sexual exposure, given the pandemic mitigation-related impacts of school closures on these factors. COVID-19-related stress was measured with a standardized scale and dichotomized at the highest quartile. Mixed effects modeling quantified how BV and STI changed over time. Longitudinal mediation analysis quantified how the relationship between COVID-19 stress and increased BV was mediated.</p><p><strong>Outcomes: </strong>Analysis outcomes were BV and STI.</p><p><strong>Results: </strong>BV and STI prevalence increased from 12.1% and 10.7% pre-COVID-19 to 24.5% and 18.1% during COVID-19, respectively. This equated to 26% (95% CI, 1.00-1.59) and 36% (95% CI, 0.98-1.88) higher relative prevalence of BV and STIs in the COVID-19 vs pre-COVID-19 periods, adjusted for numerous sociodemographic and behavioral factors. Higher COVID-19-related stress was associated with elevated depressive symptoms and feeling less safe inside the home, which were each associated with a greater likelihood of having a boyfriend. In mediation analyses, the direct effect of COVID-19-related stress on BV was small and nonsignificant, indicating that the increased BV was due to the constellation of factors that were affected during the COVID-19 pandemic.</p><p><strong>Clinical translation: </strong>These results highlight factors to help maintain reproductive health for adolescent girls in future crises, such as anticipating and mitigating mental health impacts, domestic safety concerns, and maintaining sexual health services.</p><p><strong>Strengths and limitations: </strong>Impacts of the COVID-19 pandemic on drivers of reproductive tract health among those who did not attend school or who live in different settings may differ.</p><p><strong>Conclusions: </strong>In this cohort of adolescent girls, BV and STIs increased following COVID-19-related school closures, and risk was mediated by depressive symptoms and feeling less safe in the home, which led to a higher likelihood of sexual exposures.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 3","pages":"qfae045"},"PeriodicalIF":2.6,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11264406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of information accuracy and clarity: ChatGPT responses to the most frequently asked questions about premature ejaculation.","authors":"Mehmet Fatih Şahin, Anil Keleş, Rıdvan Özcan, Çağrı Doğan, Erdem Can Topkaç, Murat Akgül, Cenk Murat Yazıci","doi":"10.1093/sexmed/qfae036","DOIUrl":"10.1093/sexmed/qfae036","url":null,"abstract":"<p><strong>Background: </strong>Premature ejaculation (PE) is the most prevalent sexual dysfunction in men, and like many diseases and conditions, patients use Internet sources like ChatGPT, which is a popular artificial intelligence-based language model, for queries about this andrological disorder.</p><p><strong>Aim: </strong>The objective of this research was to evaluate the quality, readability, and understanding of texts produced by ChatGPT in response to frequently requested inquiries on PE.</p><p><strong>Methods: </strong>In this study we used Google Trends to identify the most frequently searched phrases related to PE. Subsequently, the discovered keywords were methodically entered into ChatGPT, and the resulting replies were assessed for quality using the Ensuring Quality Information for Patients (EQIP) program. The produced texts were assessed for readability using the Flesch-Kincaid Grade Level (FKGL), Flesch Reading Ease Score (FRES), and DISCERN metrics.</p><p><strong>Outcomes: </strong>This investigation has identified substantial concerns about the quality of texts produced by ChatGPT, highlighting severe problems with reading and understanding.</p><p><strong>Results: </strong>The mean EQIP score for the texts was determined to be 45.93 ± 4.34, while the FRES was 15.8 ± 8.73. Additionally, the FKGL score was computed to be 15.68 ± 1.67 and the DISCERN score was 38.1 ± 3.78. The comparatively low average EQIP and DISCERN scores suggest that improvements are required to increase the quality and dependability of the presented information. In addition, the FKGL scores indicate a significant degree of linguistic intricacy, requiring a level of knowledge comparable to about 14 to 15 years of formal schooling in order to understand. The texts about treatment, which are the most frequently searched items, are more difficult to understand compared to other texts about other categories.</p><p><strong>Clinical implications: </strong>The results of this research suggest that compared to texts on other topics the PE texts produced by ChatGPT exhibit a higher degree of complexity, which exceeds the recommended reading threshold for effective health communication. Currently, ChatGPT is cannot be considered a substitute for comprehensive medical consultations.</p><p><strong>Strengths and limitations: </strong>This study is to our knowledge the first reported research investigating the quality and comprehensibility of information generated by ChatGPT in relation to frequently requested queries about PE. The main limitation is that the investigation included only the first 25 popular keywords in English.</p><p><strong>Conclusion: </strong>ChatGPT is incapable of replacing the need for thorough medical consultations.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 3","pages":"qfae036"},"PeriodicalIF":2.6,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11144523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141236991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is erectile dysfunction associated with osteoarthritis and rheumatoid arthritis? Insights from a population-based study.","authors":"Yuxin Yan, Liyu Zhou, Rui La, Wu Xu, Lisong Li, Dinghua Jiang, Lixin Huang, Qian Wu","doi":"10.1093/sexmed/qfae028","DOIUrl":"10.1093/sexmed/qfae028","url":null,"abstract":"<p><strong>Background: </strong>The correlation between osteoarthritis (OA) and rheumatoid arthritis (RA), both significant components of arthritis, and erectile dysfunction (ED) has yet to be thoroughly investigated.</p><p><strong>Aim: </strong>In this study we aimed to assess the association of OA and RA with ED.</p><p><strong>Methods: </strong>In this observational study we used data from the National Health and Nutrition Examination Survey, which was conducted between 2001 and 2004. Various statistical analyses were employed to investigate the associations of OA and RA with ED, including multivariable logistic regression analysis and subgroup analysis.</p><p><strong>Outcomes: </strong>The primary outcome for this investigation was arthritis as assessed through self-reporting.</p><p><strong>Results: </strong>In this comprehensive nationally representative survey spanning 4 years, our findings revealed a notably elevated incidence of ED within both OA and RA populations in comparison to the general population. Additional research is imperative to provide a deeper understanding of these correlations and their potential implications for both pathogenesis and treatment strategies.</p><p><strong>Clinical implications: </strong>The research outcomes reported here may serve as a valuable guide for clinicians to assist OA and RA patientsin staying vigilant in addressing their sexual health concerns.</p><p><strong>Strengths and limitations: </strong>We explored the association of OA and RA with ED. However, this is only a cross-sectional study.</p><p><strong>Conclusion: </strong>In this comprehensive nationally representative survey spanning 4 years, our findings revealed a notably elevated incidence of ED within both OA and RA patient populations in comparison to the general population. Ongoing research is imperative to provide a deeper understanding of these correlations.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 3","pages":"qfae028"},"PeriodicalIF":2.6,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11144276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory proteins mediate male erectile dysfunction via plasma metabolites.","authors":"Zhen Kang, Zhuo-Rui Zhang, Zhi-Yuan Feng, Long-Shen Dong, Junfeng Yang","doi":"10.1093/sexmed/qfae027","DOIUrl":"10.1093/sexmed/qfae027","url":null,"abstract":"<p><strong>Background: </strong>There are no clear conclusions as to whether inflammatory proteins and plasma metabolites influence erectile dysfunction (ED).</p><p><strong>Aim: </strong>In this research, we used Mendelian randomization (MR) analysis to discover a causal relationship between inflammatory proteins, plasma metabolites, and ED.</p><p><strong>Methods: </strong>Raw data with ED, inflammatory proteins, and plasma metabolites were obtained from the MRC IEU OpenGWAS and FinnGen database. After a series of screenings, the remaining single nucleotide polymorphisms were selected as instrumental variables or MR analysis to assess the relationship between genetically predicted inflammatory proteins or plasma metabolites and the pathogenesis of ED.</p><p><strong>Outcomes: </strong>The relationship between inflammatory factors and ED was fully analyzed and elaborated.</p><p><strong>Results: </strong>In the inverse variance-weighted method, there exists a significant causal relationship between 4 types of genetically predicted inflammatory proteins and 50 types of plasma metabolites with the incidence of ED. The primary discovery is that 3 inflammatory proteins, fibroblast growth factor 5, interleukin-22 receptor subunit alpha-1, and protein S100-A12, can impact the risk of ED through plasma metabolites.</p><p><strong>Clinical implications: </strong>ED metabolites and inflammatory proteins are also closely associated with cardiovascular diseases, warranting further exploration.</p><p><strong>Strengths and limitations: </strong>Our analysis is based on a European population, limiting its generalizability, the genome-wide association study dataset for ED has a relatively small number of cases, and we hope for larger genome-wide association study datasets for future validation.</p><p><strong>Conclusion: </strong>This study has identified that inflammatory proteins can influence ED through plasma metabolites.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 3","pages":"qfae027"},"PeriodicalIF":2.6,"publicationDate":"2024-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two laterally based scrotal pedicled flap grafts in the treatment of penile skin necrosis due to ring incarceration: a case series.","authors":"Jiaokui Xie","doi":"10.1093/sexmed/qfae030","DOIUrl":"10.1093/sexmed/qfae030","url":null,"abstract":"<p><strong>Introduction: </strong>The rise in the incidence of penile ring incarceration has led to additional cases of ischemic necrosis of the penile skin. Two laterally based scrotal pedicled flaps (LSPFs), noted for their rich blood flow and skin source, resemble penile skin and are the preferred donor sites for repairing such necrosis.</p><p><strong>Aims: </strong>This study summarizes the outcomes of 2 LSPF grafts for the treatment of penile skin necrosis.</p><p><strong>Methods: </strong>Data were collected from 5 patients with penile skin necrosis due to ring incarceration who sought treatment at Ankang Central Hospital between 2012 and 2023.</p><p><strong>Results: </strong>All patients exhibited varying degrees of necrosis in the urethral corpus cavernosum and the penis's anterior tip. Two LSPFs were used for wound repair, with direct suturing of the donor site. None of the 5 patients experienced flap necrosis postsurgery, and they regained normal urination function. The patients reported satisfaction with both the aesthetic and functional results.</p><p><strong>Conclusion: </strong>Two LSPF grafts are an effective approach for repairing penile skin defects. They reliably cover necrotic penile skin defects, prevent further wound progression, preserve penile structure, and improve patients' life quality.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 2","pages":"qfae030"},"PeriodicalIF":2.6,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11131015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ROUX-en-Y gastric bypass surgery improves metabolic syndrome-related erectile dysfunction in mice via the IRS-1/PI3K/AKT/eNOS pathway.","authors":"Zhenxing Hu, Keming Chen, Haitao Dai, Zhiyong Lv, Jian Li, Puguang Yu, Jiajing Feng, Alqaisi Mohammed Abdulkarem, Haifeng Wu, Rui He, Guangyong Li","doi":"10.1093/sexmed/qfae029","DOIUrl":"10.1093/sexmed/qfae029","url":null,"abstract":"<p><strong>Objective: </strong>Although many clinical studies have shown that ROUX-en-Y gastric bypass (RYGB) surgery significantly improves metabolic syndrome-related erectile dysfunction (MED), the role and mechanism are unclear.</p><p><strong>Aim: </strong>In this study we used a mouse model to explore how RYGB improves MED induced by a high-fat diet (HFD).</p><p><strong>Methods: </strong>We established a mouse model of metabolic syndrome by feeding an HFD for 16 weeks. The mice were randomly assigned to the standard chow diet (SCD), HFD, or RYGB groups. Body weight, fasting blood glucose, plasma insulin, and total plasma cholesterol were analyzed. Erectile responses were evaluated by determining the mean systolic blood pressure and the intracavernosal pressure (ICP). Penile histologic examination (Masson's trichrome and immunohistochemical stain) and Western blot were performed.</p><p><strong>Result: </strong>Compared with the SCD group, the ICP in the sham group was significantly lower, and the ICP of the RYGB was significantly increased. Masson's trichrome and immunohistochemical staining showed that the content of endothelium and smooth muscle in the corpus cavernosum of mice with MED was significantly reduced. Western blot analysis showed a significant decrease in α-smooth muscle actin and a significant increase in osteopontin in penile tissue in the sham group, which was improved by RYGB surgery. Furthermore, RYGB significantly increased IRS-1/PI3K/Akt/eNOS phosphorylation.</p><p><strong>Clinical translation: </strong>In this study we explored the mechanism of bariatric surgery to improve erectile dysfunction associated with metabolic syndrome and provided a theoretical basis for clinical research.</p><p><strong>Strengths and limitations: </strong>First, we did not investigate the mechanism by which RYGB affects the IRS-1/PI3K/Akt/eNOS signaling pathway. Second, the effect of the IRS-1/PI3K/Akt/eNOS signaling pathway on the function of corpus cavernosum endothelial cells and smooth muscle cells remains to be investigated in cellular studies.</p><p><strong>Conclusion: </strong>This study demonstrated that RYGB may not only improve metabolic parameters but also restore erectile function in MED patients. The mechanism of the therapeutic effect of RYGB may be reactivation of the IRS-1/PI3K/Akt/eNOS pathway.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 2","pages":"qfae029"},"PeriodicalIF":2.6,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11134102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141180955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The risk of sexual dysfunction in Chinese women with recurrent pregnancy loss and the associated factors: a multicenter cross-sectional study.","authors":"Chuanjiao Liu, Yiduo Zhang, Qian Xu, Chen Yang, Yuanting Tang, Qiong Zhang, Xiumei Liu, Yangang Yue, Fan Yu","doi":"10.1093/sexmed/qfae031","DOIUrl":"10.1093/sexmed/qfae031","url":null,"abstract":"<p><strong>Background: </strong>Recurrent pregnancy loss (RPL) is a severe traumatic event for women of childbearing age. However, the association between RPL and female sexual dysfunction was unknown.</p><p><strong>Aim: </strong>The study sought to investigate the association between RPL and sexual dysfunction, and to explore the risk factors of sexual dysfunction for RPL patients.</p><p><strong>Methods: </strong>A multicenter cross-sectional study involving both RPL patients and healthy women was performed in 3 different hospitals in West China from May 2021 to January 2023. Baseline information including sociodemographic data and disease histories were collected. The Female Sexual Function Index (FSFI) was used to assess the sexual function of participants.</p><p><strong>Outcomes: </strong>The main outcome was the proportion of women at increased risk of sexual dysfunction (total FSFI scores <26.55), and the secondary outcome was risk factors of sexual dysfunction in RPL patients.</p><p><strong>Results: </strong>A total of 233 RPL patients and 185 healthy women were included in this study. RPL patients had significantly lower total FSFI scores (median 31.7 [interquartile range, 26.6-33.5] vs 33.0 [interquartile range, 31.2-34.1]; <i>P <</i> .001) and a significantly higher risk of sexual dysfunction than healthy women (24.9% vs 8.6%; <i>P <</i> .001). Body mass index >24 kg/m² (adjusted odds ratio [OR], 4.132; 95% confidence interval [CI], 1.902-8.976, <i>P <</i> .001), working >8 h/d (adjusted OR, 2.111; 95% CI, 1.020-4.369, <i>P =</i> .044), and unexplained RPL (adjusted OR, 3.785; 95% CI, 1.967-7.280, <i>P <</i> .001) were independent risk factors of sexual dysfunction for RPL patients.</p><p><strong>Clinical implications: </strong>RPL patients, especially those patients with the previously mentioned risk factors, should be focused on the risk of sexual dysfunction, and appropriate preventions could be applied.</p><p><strong>Strength and limitations: </strong>We explored the association between RPL and sexual dysfunction and explored the risk factors of sexual dysfunction among RPL patients for the first time, and the multicenter data increased the generalizability of results. However, the cross-sectional design did not provide an exact causal relationship between RPL and sexual dysfunction, and potential risk factors related to mental health were not investigated.</p><p><strong>Conclusion: </strong>RPL patients were at an increased risk of sexual dysfunction. Overweight, fatigue caused by work, and unexplained RPL were risk factors of sexual dysfunction for RPL patients.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 2","pages":"qfae031"},"PeriodicalIF":2.6,"publicationDate":"2024-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11128721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ovotesticular disorder of sexual development manifested as hematospermia: a case report and literature review.","authors":"Chengdong Shi, Yuxiong Wang, Guoqiang Zeng, Hongliang Cao, Mo Chen, Yuantao Wang","doi":"10.1093/sexmed/qfae026","DOIUrl":"10.1093/sexmed/qfae026","url":null,"abstract":"<p><strong>Background: </strong>Ovotesticular disorder of sexual development (OT-DSD) is a rare sexual development disorder defined by the simultaneous existence of testicular and ovarian tissues (including follicular) in the same- or opposite-sex glands of an individual, with an incidence rate of about 1 in 100 000.</p><p><strong>Aim: </strong>This report aims to supplement the clinical presentation, pathology, diagnosis, and treatment of OT-DSD and to improve the diagnostic ability of clinicians for modified disease.</p><p><strong>Methods: </strong>This article is a retrospective analysis of a case of OT-DSD at our institution. Additionally, a comprehensive search of the PubMed database with the keywords \"ovotesticular disorder of sexual development\" or \"true hermaphroditism\" was conducted between 1956 and 2024, resulting in approximately 250 cases, and the results of the search are summarized.</p><p><strong>Results: </strong>The patient, a 44-year-old male, sought treatment at our hospital on February 6, 2023, primarily due to \"intermittent hematospermia for over a month.\" He stated that it was discovered during infancy that his right scrotum was empty and lacking a testicle. Due to the low local medical services and the low-income family's economic conditions, he did not seek further diagnosis and treatment. After admission, the patient underwent computed tomography and magnetic resonance imaging and decided to undergo robot-assisted pelvic mass resection, which was pathologically confirmed as OT-DSD.</p><p><strong>Outcomes: </strong>The patient's definitive diagnosis was provided by postoperative pathology, and although the patient ultimately had a favorable outcome, diagnosis and treatment were delayed due to his atypical clinical presentation.</p><p><strong>Strengths and limitations: </strong>This is a single case report; however, uncommon clinical presentations of rare diseases were identified, and a literature review was conducted. Unfortunately, there are some important missing data in the patient's medical history, including hormone assessment (testosterone, luteinizing hormone, follicle-stimulating hormone), tumor marker examination, semen analysis, scrotal ultrasound, and chromosomal analysis.</p><p><strong>Conclusion: </strong>Patients with OT-DSD have diverse types of gonads, chromosomal karyotypes, and phenotypes of external genitalia, and further exploration and research are needed for early diagnosis and treatment. In addition, cases of OT-DSD with fertility and no ambiguous genitalia are even rarer. This case guides us for adult patients with no ambiguous genitalia: if there is an inability to palpate 1 or both gonads and there is intermittent hematospermia, the possibility of OT-DSD should be suspected.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 2","pages":"qfae026"},"PeriodicalIF":2.6,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11307195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141907660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: The effect of local anesthetic on the hypersensitive and nonsensitive areas of the penis is different in primary premature ejaculation: a pilot study.","authors":"","doi":"10.1093/sexmed/qfae037","DOIUrl":"https://doi.org/10.1093/sexmed/qfae037","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/sexmed/qfae020.].</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 2","pages":"qfae037"},"PeriodicalIF":2.6,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11100258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Translation, adaptation, and clinical validation of the Premature Ejaculation Diagnostic Tool in Spanish (Colombia).","authors":"","doi":"10.1093/sexmed/qfae032","DOIUrl":"https://doi.org/10.1093/sexmed/qfae032","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/sexmed/qfac017.].</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 2","pages":"qfae032"},"PeriodicalIF":2.6,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11101756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141066082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}