Singapore medical journal最新文献

{"title":"Parental knowledge, attitude and practice of child car restraint use in Singapore: a survey and literature review.","authors":"Xi Yun Ling, Alvin Jia-Hao Ngeow, Mary Grace Sy Tan, Daisy Kwai-Lin Chan","doi":"10.11622/smedj.2021207","DOIUrl":"10.11622/smedj.2021207","url":null,"abstract":"","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"386-390"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39647262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigation in total knee arthroplasty: a resident's friend or foe?","authors":"Cheryl Marise Peilin Tan, Tamara Lee Ting Soh, Arun-Kumar Kaliya-Perumal, Tong Leng Tan","doi":"10.11622/smedj.2021212","DOIUrl":"10.11622/smedj.2021212","url":null,"abstract":"","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"391-396"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39647260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carcinoma buccal mucosa treated with definitive hypofractionated accelerated radiotherapy: a retrospective analysis of treatment outcomes.","authors":"Geethu Babu, Rejnish Ravikumar, Malu Rafi, Zuzaki Sharafuddin, Arun Shankar S, Preethi Sara George, Cessal Thommachan Kainickal, Ramadas Kunnambath","doi":"10.4103/singaporemedj.SMJ-2021-282","DOIUrl":"10.4103/singaporemedj.SMJ-2021-282","url":null,"abstract":"<p><strong>Introduction: </strong>Oral cancer is a major public health concern in India. Both conventional and altered fractionation radiotherapy schedules have been used in curative treatment of oral cancer. This study aimed to retrospectively evaluate the clinical profile and treatment outcomes of patients with carcinoma buccal mucosa who underwent treatment with definitive hypofractionated accelerated radiotherapy.</p><p><strong>Methods: </strong>A total of 517 patients treated from January 2011 to December 2016 were eligible for the analysis. All patients were treated with definitive hypofractionated accelerated radiotherapy schedule of 5,250 cGy in 15 fractions over 3 weeks. Survival estimates were generated using the Kaplan-Meier method.</p><p><strong>Results: </strong>At a median follow-up of 77.4 months, 473 (91.5%) patients attained complete remission with radiation therapy. The 5-year disease-free survival (DFS) and overall survival (OS) rates were 69% and 80.5%, respectively. The 5-year OS for stage I, II, III and IVa tumours was 80.3%, 84.4%, 81.4% and 73.7%, respectively, and the DFS was 75.7%, 73.2%, 69.6% and 60.2%, respectively. Age >50 years was found to be a significant factor affecting DFS ( P = 0.026) and OS ( P = 0.048) in multivariate analysis. Fifty-three (10.3%) patients developed osteoradionecrosis of the mandible.</p><p><strong>Conclusion: </strong>Excellent outcome could be achieved in less-aggressive, low-volume carcinoma of the buccal mucosa with radical accelerated hypofractionated radiotherapy. A radiotherapy schedule over a 3-week period is useful in high-volume centres.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"368-372"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The dialectics of enteral nutrition in advanced dementia.","authors":"Min Li Toon, Chin Yee Cheong, Chetna Malhotra, Philip Lin Kiat Yap","doi":"10.4103/singaporemedj.SMJ-2021-320","DOIUrl":"10.4103/singaporemedj.SMJ-2021-320","url":null,"abstract":"","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"373-375"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9180505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphologic differences in knee bone cuts between Han Chinese and Mongolian Chinese and their correlation with current knee prostheses.","authors":"Qida Zhang, Zhifeng Zhang, Zhenxian Chen, Jiayu Hu, Yusheng Qiu, Zhongmin Jin","doi":"10.11622/smedj.2021214","DOIUrl":"10.11622/smedj.2021214","url":null,"abstract":"","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"379-385"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39659181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disparities in ethnicity and metabolic disease burden in referrals to nephrology.","authors":"Yan Ting Chua, Cheang Han Leo, Horng Ruey Chua, Weng Kin Wong, Gek Cher Chan, Anantharaman Vathsala, Ye Lu Mavis Gan, Boon Wee Teo","doi":"10.4103/singaporemedj.SMJ-2022-193","DOIUrl":"10.4103/singaporemedj.SMJ-2022-193","url":null,"abstract":"<p><strong>Introduction: </strong>The profile of patients referred from primary to tertiary nephrology care is unclear. Ethnic Malay patients have the highest incidence and prevalence of kidney failure in Singapore. We hypothesised that there is a Malay predominance among patients referred to nephrology due to a higher burden of metabolic disease in this ethnic group.</p><p><strong>Methods: </strong>This is a retrospective observational cohort study. From 2014 to 2018, a coordinator and physician triaged patients referred from primary care, and determined co-management and assignment to nephrology clinics. Key disease parameters were collated on triage and analysed.</p><p><strong>Results: </strong>A total of 6,017 patients were studied. The mean age of patients was 64 ± 16 years. They comprised 57% men; 67% were Chinese and 22% were Malay. The proportion of Malay patients is higher than the proportion of Malays in the general population (13.4%) and they were more likely than other ethnicities to have ≥3 comorbidities, including diabetes mellitus, hypertension, hyperlipidaemia, coronary artery disease and stroke (70% vs. 57%, P < 0.001). Malay and Indian patients had poorer control of diabetes mellitus compared to other ethnicities (glycated haemoglobin 7.8% vs. 7.4%, P < 0.001). Higher proportion of Malay patients compared to other ethnicities had worse kidney function with estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m 2 on presentation (28% vs. 24%, P = 0.003). More ethnic Malay, Indian and younger patients missed appointments.</p><p><strong>Conclusion: </strong>A disproportionately large number of Malay patients are referred for kidney disease. These patients have higher metabolic disease burden, tend to miss appointments and are referred at lower eGFR. Reasons underpinning these associations should be identified to facilitate efforts for targeting this at-risk population, ensuring kidney health for all.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"301-306"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12200813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10161326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemoperitoneum from pancreatic tumour rupture: an unusual presentation of a rare childhood tumour.","authors":"Kar Yee Catrin Kong, Ronald Ming Ren Tan, Cheryl Bin Lin, Sashikumar Ganapathy","doi":"10.4103/singaporemedj.SMJ-2021-011","DOIUrl":"10.4103/singaporemedj.SMJ-2021-011","url":null,"abstract":"","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"348-349"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12200808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9237881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National HIV programme testing recommendations.","authors":"Chiaw Yee Choy, Chen Seong Wong, P Arun Kumar, Raymond Tzer Pin Lin, Carmen Low, Matthias Paul Han Sim Toh, Flora Huang, Dariusz Piotr Olszyna, Yii Ean Teh, Mei Fong Jaime Chien, Sophia Archuleta","doi":"10.4103/singaporemedj.SMJ-2021-466","DOIUrl":"10.4103/singaporemedj.SMJ-2021-466","url":null,"abstract":"<p><strong>Abstract: </strong>In recognition of the morbidity and mortality associated with human immunodeficiency virus (HIV), the Joint United Nations Programme on HIV/acquired immunodeficiency syndrome (AIDS) (UNAIDS) aims to end the epidemic by setting and striving to achieve the ambitious 95-95-95 targets. However, Singapore is still not performing well in the first UNAIDS target. The National HIV Programme (NHIVP) developed this set of recommendations based on an adaptation of major international guidelines from the World Health Organization and the US Centers for Disease Control and Prevention. The goals of this recommendation are: (1) to increase the uptake of HIV testing; (2) to allow earlier detection and identification of individuals with unrecognised HIV infection; (3) to facilitate linkage to clinical services; and (4) reduce further transmission of HIV infection in Singapore.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"294-300"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12200811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10020006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Testicular tumours in children: a single-centre experience.","authors":"Sajid Ali, Tariq Latif, Muhammad Ali Sheikh, Shazia Perveen, Muhammad Bilal, Albash Sarwar","doi":"10.4103/singaporemedj.SMJ-2021-414","DOIUrl":"10.4103/singaporemedj.SMJ-2021-414","url":null,"abstract":"<p><strong>Introduction: </strong>Testicular tumours in childhood have diverse characteristics for different age ranges. This study aimed to describe the pattern, presentation and outcomes of primary testicular tumours in a paediatric population.</p><p><strong>Methods: </strong>A retrospective study was conducted from January 2010 to December 2020 on children (≤18 years) with a diagnosis of primary testicular tumour. Baseline demographics, clinical characteristics, pathology, treatment and outcomes of these patients were analysed. The data were entered into IBM SPSS Statistics version 20.0. Chi-square test and Fisher's exact test were applied to find the statistical significance, which was set at P value ≤ 0.05.</p><p><strong>Results: </strong>The study included 115 males, with 85 (73.9%) patients in the prepubertal age range with a mean age of 2.53 ± 2.06 years and 30 (26.1%) patients in the postpubertal group with a mean age of 15.73 ± 1.25 years. Yolk sac tumour was the most common (62.6%) histological subtype. Majority (46.1%) of patients had stage I disease on presentation, while 29.6% had stage IV disease. All patients underwent upfront high inguinal radical orchiectomy, which was followed by platinum-based adjuvant chemotherapy in 67% of the patients. The five-year event-free survival and overall survival for all patients were 75% and 91%, respectively.</p><p><strong>Conclusion: </strong>Primary testicular tumours follow a bimodal age distribution pattern. Majority of patients can be cured with platinum-based chemotherapy despite having advanced disease at presentation.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"321-326"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12200819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10636179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parents' perceptions and experiences of physical activity in childhood cancer survivors in Singapore: a qualitative study.","authors":"Lindsey Jean Ross Weller, Debbie Grant Cavers, Neneh Rowa-Dewar","doi":"10.4103/singaporemedj.SMJ-2022-122","DOIUrl":"10.4103/singaporemedj.SMJ-2022-122","url":null,"abstract":"<p><strong>Introduction: </strong>The survival rate for childhood cancer has increased with advances in medical care. Along with this comes the growing burden of long-term side effects of cancer treatment and cancer survivorship. Childhood cancer survivors are more likely to be sedentary and have a lower quality of life. Physical activity (PA) can promote health and well-being in childhood cancer survivors, but few studies have explored the role of parents of childhood cancer survivors (PCCS) in promoting PA. This qualitative study aims to explore the perceptions of PCCS in Singapore and the role they may have with regard to PA.</p><p><strong>Methods: </strong>Participants were recruited through a local charity via email, social media and posters. One-hour semi-structured interviews were conducted online with seven parents. With consent, the interviews were recorded, transcribed verbatim and analysed using thematic analysis.</p><p><strong>Results: </strong>Our study discussed thematically parents' accounts on (1) the barriers and enablers of PA and (2) the complications of cancer that potentially affect the levels of PA in childhood cancer survivors. Parents reported that childhood cancer negatively affects the quality of life and participation in PA. The determinants of participation in PA were multifaceted, and socioecological and health belief models were used to demonstrate how these factors were interlinked.</p><p><strong>Conclusion: </strong>Participation in PA is influenced at an individual, family, community and societal level. The improved understanding facilitated by this research can be used to shape paediatric cancer care practices in Singapore and guide institutional or national policy interventions.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"314-320"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12200817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10020002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}