Singapore medical journal最新文献

筛选
英文 中文
Development of the modified Safety Attitude Questionnaire for the medical imaging department. 为医学影像科编制经修改的安全态度问卷。
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2025-01-01 Epub Date: 2023-02-06 DOI: 10.4103/singaporemedj.SMJ-2021-254
Ravi Chanthriga Eturajulu, Maw Pin Tan, Mohd Idzwan Zakaria, Karuthan Chinna, Kwan Hoong Ng
{"title":"Development of the modified Safety Attitude Questionnaire for the medical imaging department.","authors":"Ravi Chanthriga Eturajulu, Maw Pin Tan, Mohd Idzwan Zakaria, Karuthan Chinna, Kwan Hoong Ng","doi":"10.4103/singaporemedj.SMJ-2021-254","DOIUrl":"10.4103/singaporemedj.SMJ-2021-254","url":null,"abstract":"<p><strong>Introduction: </strong>Medical errors commonly occur in medical imaging departments. These errors are frequently influenced by patient safety culture. This study aimed to develop a suitable patient safety culture assessment tool for medical imaging departments.</p><p><strong>Methods: </strong>Staff members of a teaching hospital medical imaging department were invited to complete the generic short version of the Safety Attitude Questionnaire (SAQ). Internal consistency and reliability were evaluated using Cronbach's α. Confirmatory factor analysis (CFA) was conducted to examine model fit. A cut-off of 60% was used to define the percentage positive responses (PPR). PPR values were compared between occupational groups.</p><p><strong>Results: </strong>A total of 300 complete responses were received and the response rate was 75.4%. In reliability analysis, the Cronbach's α for the original 32-item SAQ was 0.941. Six subscales did not demonstrate good fit with CFA. A modified five-subscale, 22-item model (SAQ-MI) showed better fit (goodness-to-fit index ≥0.9, comparative fit index ≥ 0.9, Tucker-Lewis index ≥0.9 and root mean square error of approximation ≤0.08). The Cronbach's α for the 22 items was 0.921. The final five subscales were safety and teamwork climate, job satisfaction, stress recognition, perception of management and working condition, with PPR of 62%, 68%, 57%, 61% and 60%, respectively. Statistically significant differences in PPR were observed between radiographers, doctors and others occupational groups.</p><p><strong>Conclusion: </strong>The modified five-factor, 22-item SAQ-MI is a suitable tool for the evaluation of patient safety culture in a medical imaging department. Differences in patient safety culture exist between occupation groups, which will inform future intervention studies.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"33-40"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9222521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune thrombocytopenia in infants: a retrospective study with comparison to toddlers. 婴儿免疫性血小板减少症:一项与幼儿比较的回顾性研究。
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2025-01-01 Epub Date: 2023-03-02 DOI: 10.4103/singaporemedj.SMJ-2021-184
Anselm Chi-Wai Lee
{"title":"Immune thrombocytopenia in infants: a retrospective study with comparison to toddlers.","authors":"Anselm Chi-Wai Lee","doi":"10.4103/singaporemedj.SMJ-2021-184","DOIUrl":"10.4103/singaporemedj.SMJ-2021-184","url":null,"abstract":"<p><strong>Introduction: </strong>Immune thrombocytopenia (ITP) is the most common cause of acquired bleeding in childhood, but little is known about the clinical course and outcomes in infants with ITP.</p><p><strong>Methods: </strong>This is a retrospective study of all infants (1-12 months of age) and toddlers (13-47 months of age) diagnosed with ITP from a single centre during a 13-year period. The following data were compared between the two patients groups: demographics, severity of bleeding, platelet counts, duration of illness, development of chronic ITP, treatment and association with recent vaccination.</p><p><strong>Results: </strong>Twenty-two infants and 30 toddlers were diagnosed and followed up for ITP during the study period. Infants with ITP generally had minor or mild bleeding (19, 86.4%) and seldom required treatment (7, 31.8%), and their thrombocytopenia resolved at a mean of 1.90 months after diagnosis. Besides age, the sex ratio, severity of bleeding, platelet counts and proportion that required treatment were comparable between infants and toddlers. Fewer infants developed chronic ITP (1/22 vs. 9/30, P = 0.032), but more infants had a history of vaccination in the preceding 6 weeks prior to diagnosis of ITP (13/22 vs. 1/30, P < 0.001).</p><p><strong>Conclusion: </strong>ITP in infants is almost always a self-limiting and transient illness, and the majority of cases do not require treatment.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"20-23"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9180495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk and protective factors associated with adolescent depression in Singapore: a systematic review. 新加坡青少年抑郁症的相关风险和保护因素:系统回顾。
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2025-01-01 Epub Date: 2023-04-26 DOI: 10.4103/singaporemedj.SMJ-2021-192
Wei Sheng Goh, Jun Hao Norman Tan, Yang Luo, Sok Hui Ng, Mohamed Sufyan Bin Mohamed Sulaiman, John Chee Meng Wong, Victor Weng Keong Loh
{"title":"Risk and protective factors associated with adolescent depression in Singapore: a systematic review.","authors":"Wei Sheng Goh, Jun Hao Norman Tan, Yang Luo, Sok Hui Ng, Mohamed Sufyan Bin Mohamed Sulaiman, John Chee Meng Wong, Victor Weng Keong Loh","doi":"10.4103/singaporemedj.SMJ-2021-192","DOIUrl":"10.4103/singaporemedj.SMJ-2021-192","url":null,"abstract":"<p><strong>Introduction: </strong>Adolescent depression is prevalent, and teen suicide rates are on the rise locally. A systemic review to understand associated risk and protective factors is important to strengthen measures for the prevention and early detection of adolescent depression and suicide in Singapore. This systematic review aims to identify the factors associated with adolescent depression in Singapore.</p><p><strong>Methods: </strong>A systematic search on the following databases was performed on 21 May 2020: PubMed, EMBASE and PsycINFO. Full texts were reviewed for eligibility, and the included studies were appraised for quality using the Newcastle Ottawa Scale. Narrative synthesis of the finalised articles was performed through thematic analysis.</p><p><strong>Results: </strong>In total, eight studies were included in this review. The four factors associated with adolescent depression identified were: (1) sociodemographic factors (gender, ethnicity); (2) psychological factors, including childhood maltreatment exposure and psychological constructs (hope, optimism); (3) coexisting chronic medical conditions (asthma); and (4) lifestyle factors (sleep inadequacy, excessive internet use and pathological gaming).</p><p><strong>Conclusion: </strong>The identified factors were largely similar to those reported in the global literature, except for sleep inadequacy along with conspicuously absent factors such as academic stress and strict parenting, which should prompt further research in these areas. Further research should focus on current and prospective interventions to improve mental health literacy, targeting sleep duration, internet use and gaming, and mitigating the risk of depression in patients with chronic disease in the primary care and community setting.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"2-14"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9447018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paediatric one-day admission: why and is it necessary? 儿科一日入院:为什么需要?
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2025-01-01 Epub Date: 2023-02-15 DOI: 10.4103/singaporemedj.SMJ-2021-117
Jing Zhan Lock, Zi Xean Khoo, Jen Heng Pek
{"title":"Paediatric one-day admission: why and is it necessary?","authors":"Jing Zhan Lock, Zi Xean Khoo, Jen Heng Pek","doi":"10.4103/singaporemedj.SMJ-2021-117","DOIUrl":"10.4103/singaporemedj.SMJ-2021-117","url":null,"abstract":"<p><strong>Introduction: </strong>Paediatric patients admitted to the inpatient units from the emergency department (ED) are increasing, but the mean length of stay has fallen significantly. We aimed to determine the reasons behind paediatric one-day admissions in Singapore and to assess their necessity.</p><p><strong>Methods: </strong>A retrospective study involving paediatric patients who were admitted from a general ED of an adult tertiary hospital to a paediatric tertiary hospital between 1 August 2018 and 30 April 2020. One-day admission was defined as an inpatient stay of less than 24 h from the time of admission to discharge. An unnecessary admission was defined as one with no diagnostic test ordered, intravenous medication administered, therapeutic procedure performed or specialty review made in the inpatient unit. Data were captured in a standardised form and analysed.</p><p><strong>Results: </strong>There were 13,944 paediatric attendances - 1,160 (8.3%) paediatric patients were admitted. Among these, 481 (41.4%) were one-day admissions. Upper respiratory tract infection (62, 12.9%), gastroenteritis (60, 12.5%) and head injury (52, 10.8%) were the three most common conditions. The three most common reasons for ED admissions were inpatient treatment (203, 42.2%), inpatient monitoring (185, 38.5%) and inpatient diagnostic investigations (32, 12.3%). Ninety-six (20.0%) one-day admissions were unnecessary.</p><p><strong>Conclusion: </strong>Paediatric one-day admissions present an opportunity to develop and implement interventions targeted at the healthcare system, the ED, the paediatric patient and their caregiver, in order to safely slow down and perhaps reverse the trend of increased hospital admissions.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"15-19"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9363620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrointestinal transit time of radiopaque ingested foreign bodies in children: experience of two paediatric tertiary centres. 儿童摄入不透射线的异物的胃肠道传递时间:两个儿科三级中心的经验。
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2025-01-01 Epub Date: 2023-04-25 DOI: 10.4103/singaporemedj.SMJ-2021-408
Chen Xiang Ang, Win Kai Mun, Marion Margaret Aw, Diana Lin, Shu-Ling Chong, Lin Yin Ong, Shireen Anne Nah
{"title":"Gastrointestinal transit time of radiopaque ingested foreign bodies in children: experience of two paediatric tertiary centres.","authors":"Chen Xiang Ang, Win Kai Mun, Marion Margaret Aw, Diana Lin, Shu-Ling Chong, Lin Yin Ong, Shireen Anne Nah","doi":"10.4103/singaporemedj.SMJ-2021-408","DOIUrl":"10.4103/singaporemedj.SMJ-2021-408","url":null,"abstract":"<p><strong>Introduction: </strong>Foreign body (FB) ingestion is a common paediatric emergency. While guidelines exist for urgent intervention, less is known of the natural progress of FBs passing through the gastrointestinal tract (GIT). We reviewed these FB transit times in an outpatient cohort.</p><p><strong>Methods: </strong>A retrospective review was performed on all children (≤18 years) treated for radiopaque FB ingestion at two major tertiary paediatric centres from 2015 to 2016. Demographic data, FB types, outcomes and hospital visits (emergency department [ED] and outpatient) were recorded. All cases discharged from the ED with outpatient follow-up were included. We excluded those who were not given follow-up appointments and those admitted to inpatient wards. We categorised the outcomes into confirmed passage (ascertained via abdominal X-ray or reported direct stool visualisation by patients/caregivers) and assumed passage (if patients did not attend follow-up appointments).</p><p><strong>Results: </strong>Of the 2,122 ED visits for FB ingestion, 350 patients who were given outpatient follow-up appointments were reviewed (median age 4.35 years [range: 0.5-14.7], 196 [56%] male). The largest proportion (16%) was aged 1-2 years. Coins were the most common ingested FB, followed by toys. High-risk FB (magnets or batteries) formed 9% of cases ( n =33). The 50 th centile for FB retention was 8, 4 and 7 days for coins, batteries and other radiopaque FBs, respectively; all confirmed passages occurred at 37, 7 and 23 days, respectively. Overall, 197 (68%) patients defaulted on their last given follow-up.</p><p><strong>Conclusion: </strong>This study provides insight into the transit times of FB ingested by children, which helps medical professionals to decide on the optimal time for follow-up visits and provide appropriate counsel to caregivers.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"24-27"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9439943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of metallic ureteric stents for chronic ureteric obstruction and its association with value-based care. 使用金属输尿管支架治疗慢性输尿管梗阻及其与价值导向型护理的关系。
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2025-01-01 Epub Date: 2023-02-01 DOI: 10.4103/singaporemedj.SMJ-2021-418
Yu Xi Terence Law, Ang Zhou, David Terrence Consigliere, Benjamin Yen Seow Goh, Ho Yee Tiong
{"title":"Use of metallic ureteric stents for chronic ureteric obstruction and its association with value-based care.","authors":"Yu Xi Terence Law, Ang Zhou, David Terrence Consigliere, Benjamin Yen Seow Goh, Ho Yee Tiong","doi":"10.4103/singaporemedj.SMJ-2021-418","DOIUrl":"10.4103/singaporemedj.SMJ-2021-418","url":null,"abstract":"<p><strong>Introduction: </strong>We aimed to compare the real-world data and our clinical experience with metallic stents (MSs) and conventional polymeric stents (PSs) in the management of both malignant and benign chronic ureteric obstruction (CUO), in terms of clinical outcomes and costs.</p><p><strong>Methods: </strong>Clinical data from our institution, including outcomes for all ureteric stents inserted for long-term management of CUO from all causes from 2014 to 2017, were retrospectively reviewed and compared between the MS and PS episodes.</p><p><strong>Results: </strong>A total of 247 stents were placed in 63 patients with CUO over the 4-year study period. Of these, 45 stents were MSs. There was no significant difference in all baseline characteristics between the MS and PS groups, except for the aetiology of obstructive cause. Mean indwelling stent duration was significantly greater for MS than for PS (228.6 ± 147.0 vs. 146.1 ± 66.0 days, P < 0.001), thereby leading to lower average number of stent changes per year in the MS group compared to the PS group (1.4 vs. 6.3 times, respectively). Despite the higher unit cost of MS compared to PS, there was no significant mean cost difference overall (cost per dwelling day SGD 7.82 ± SGD 10.44 vs. SGD 8.23 ± SGD 20.50, P = 0.888).</p><p><strong>Conclusion: </strong>Resonance MS is a better option than PS to manage CUO from malignant and benign causes because its significantly longer indwelling time mitigates the higher unit cost of the stent. It potentially reduces the number of procedures and operations in patients. Thus, it should be considered for all patients with CUO requiring long-term ureteric drainage.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"28-32"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9237884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical predictors of acute kidney injury in children with acute post-streptococcal glomerulonephritis: a tertiary centre experience. 链球菌感染后急性肾小球肾炎患儿急性肾损伤的临床预测因素:一家三级中心的经验。
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2025-01-01 Epub Date: 2023-01-06 DOI: 10.4103/singaporemedj.SMJ-2021-092
Wan Adlina Wan Yusof, Najib Majdi Yaacob, Ariffin Nasir, Surini Yusoff, Mohamad Ikram Ilias
{"title":"Clinical predictors of acute kidney injury in children with acute post-streptococcal glomerulonephritis: a tertiary centre experience.","authors":"Wan Adlina Wan Yusof, Najib Majdi Yaacob, Ariffin Nasir, Surini Yusoff, Mohamad Ikram Ilias","doi":"10.4103/singaporemedj.SMJ-2021-092","DOIUrl":"10.4103/singaporemedj.SMJ-2021-092","url":null,"abstract":"","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"54-57"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9183271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of echinocandins versus triazoles or amphotericin B in the treatment of invasive fungal infections in paediatric patients: a systematic review. 棘白菌素与三唑或两性霉素B治疗儿科患者侵袭性真菌感染的疗效和安全性:一项系统综述。
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2025-01-01 Epub Date: 2023-08-23 DOI: 10.4103/singaporemedj.SMJ-2021-173
Lu Lu Htet, Lay Nee Wang, Yi Xin Liew
{"title":"Efficacy and safety of echinocandins versus triazoles or amphotericin B in the treatment of invasive fungal infections in paediatric patients: a systematic review.","authors":"Lu Lu Htet, Lay Nee Wang, Yi Xin Liew","doi":"10.4103/singaporemedj.SMJ-2021-173","DOIUrl":"10.4103/singaporemedj.SMJ-2021-173","url":null,"abstract":"","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"58-62"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10168028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the COVID-19 XBB Omicron subvariant signal the beginning of the end of the pandemic? COVID-19 XBB Omicron 子变体是否预示着大流行开始结束?
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2024-12-01 Epub Date: 2022-12-01 DOI: 10.4103/singaporemedj.SMJ-2022-180
Jinghao Nicholas Ngiam, Abdurrahmaan Al-Mubaarak, Sebastian Maurer-Stroh, Paul Anantharajah Tambyah
{"title":"Does the COVID-19 XBB Omicron subvariant signal the beginning of the end of the pandemic?","authors":"Jinghao Nicholas Ngiam, Abdurrahmaan Al-Mubaarak, Sebastian Maurer-Stroh, Paul Anantharajah Tambyah","doi":"10.4103/singaporemedj.SMJ-2022-180","DOIUrl":"10.4103/singaporemedj.SMJ-2022-180","url":null,"abstract":"<p><strong>Abstract: </strong>All pandemic viruses have eventually adapted to human hosts so that they become more transmissible and less virulent. The XBB Omicron subvariant is rapidly becoming the dominant strain of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Singapore from October 2022 and is one of several variants circulating globally with the potential to dominate autumn/winter waves in different countries. The XBB Omicron subvariant has demonstrated increased transmissibility through an apparent propensity for immune evasion. This is to be expected in the natural evolution of a virus in a population highly vaccinated with a vaccine targeting the spike protein of the original Wuhan strain of the virus. This review explores the important implications of the rising prevalence of the SARS-CoV-2 Omicron subvariant for public health in Singapore and beyond.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"658-664"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10540990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Localised swelling at sites of dermal filler injections following administration of Covid-19 vaccines: a systematic review. 注射Covid-19疫苗后皮肤填充物部位局部肿胀:一项系统综述
IF 1.7 4区 医学
Singapore medical journal Pub Date : 2024-12-01 Epub Date: 2023-04-13 DOI: 10.4103/singaporemedj.SMJ-2021-157
Chew Lip Ng, Evelyn Yuxin Tay, Alwyn Ray D'Souza
{"title":"Localised swelling at sites of dermal filler injections following administration of Covid-19 vaccines: a systematic review.","authors":"Chew Lip Ng, Evelyn Yuxin Tay, Alwyn Ray D'Souza","doi":"10.4103/singaporemedj.SMJ-2021-157","DOIUrl":"10.4103/singaporemedj.SMJ-2021-157","url":null,"abstract":"<p><strong>Introduction: </strong>Localised swelling at sites of filler injections has been reported in the Moderna mRNA-1273 coronavirus disease 2019 (COVID-19) vaccine trial.</p><p><strong>Methods: </strong>We conducted a review of the existing data and literature on the potential pathophysiology for this adverse event and its potential management.</p><p><strong>Results: </strong>Data from the Moderna and Pfizer COVID-19 vaccine Phase 3 trial and one case series were available. Three out of 30,400 subjects developed possible filler reaction in the Moderna trial. Two other cases were reported after emergency use authorisation. Reactions occurred at a mean of 1.4 days post-vaccination. Fillers were injected at a mean of 14.1 months before vaccination. Areas involved included lips, infraorbital areas and tear troughs. Treatment included observation, corticosteroids, antihistamine, hyaluronidase and 5-fluorouracil.</p><p><strong>Conclusion: </strong>Rare, self-limiting adverse reactions to dermal fillers have been reported following COVID-19 vaccination. Clinicians should be aware of this clinical phenomenon and its management, as vaccination is carried out globally.</p>","PeriodicalId":21752,"journal":{"name":"Singapore medical journal","volume":" ","pages":"665-668"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9383468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信