Scientific African最新文献

{"title":"In-silico analysis and design of quinoline-based hybrids with oxadiazole and triazole frameworks as anti-diabetic agents","authors":"Khalifa Sunusi Aminu ,&nbsp;Adamu Uzairu ,&nbsp;Vipin Kumar Mishra ,&nbsp;Stephen Eyije Abechi ,&nbsp;Gideon Adamu Shallangwa ,&nbsp;Abdullahi Bello Umar ,&nbsp;Saumya Verama","doi":"10.1016/j.sciaf.2025.e02631","DOIUrl":"10.1016/j.sciaf.2025.e02631","url":null,"abstract":"<div><div>In this study, a quantitative structure-activity relationship (QSAR) approach was employed to predict the inhibitory activities of quinoline-based hybrids as potential inhibitors of α-glucosidase, an enzyme crucial in carbohydrate metabolism. The predictive models were generated using genetic function approximation (GFA) and among them, model 2 emerges as the most effective boasting validation metrics of correlation coefficient of the training set (R²_trn) = 0.909, adjusted correlation coefficient (R²_adj) = 0.889, cross-validation coefficient (Q²_cv) = 0.835 and correlation coefficient of test set (R²_test) = 0.745. Statistical evaluations, encompassing Mean effect, p-values, Y-scrambling and applicability domain analysis, confirmed the impact of the descriptors, showed statistical significance and reliability of the selected model. Subsequently, four potent compounds were designed, and their inhibitory activities were predicted. Remarkably, the designed compounds exhibited superior inhibitory potential compared to the template compound used as a reference. Furthermore, detailed analysis of the binding interactions of the designed compounds within the active site of the target receptor pdb id: (3TOP), revealed a strong binding affinity surpassing that of acarbose, a known α-glucosidase inhibitor. The dynamic simulations of complex with higher scores demonstrated remarkable stability through various analyses, indicating their potential as promising candidates for diabetes treatment. The (ADME) properties of the designed compounds were also investigated, indicating their pharmacological effectiveness and potential as drug candidates. Additionally, Density Functional Theory (DFT) studies highlighted compound 2 as being particularly reactive and possessing a propensity for electron transfer or donation. This research offers valuable insights for designing future α-glucosidase inhibitors with increased potency.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"28 ","pages":"Article e02631"},"PeriodicalIF":2.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood sugar regulating activity and safety profile of hydrolysate of Luffa cylindrica seed protein in rats with alloxan-induced diabetes","authors":"Rotimi Olusanya Arise ,&nbsp;Jahswill Osifade ,&nbsp;Daniel Afolayan ,&nbsp;Abimbola Kemisola Arise ,&nbsp;Oluwasola Michael Ojo ,&nbsp;Saheed Olatunbosun Akiode","doi":"10.1016/j.sciaf.2025.e02629","DOIUrl":"10.1016/j.sciaf.2025.e02629","url":null,"abstract":"<div><div>Diabetes mellitus cases are projected to rise by 114 % from 2000 to 2030. Bioactive peptides from <em>Luffa cylindrica</em> seeds (LCS) have been reported to possess pharmacological properties which have not been validated <em>in vivo</em>. The study evaluated the antidiabetic activity of hydrolysate of <em>Luffa cylindrica</em> seed protein (LSPH) and its safety in rats with diabetes induced by alloxan (intraperitoneal injection - 150 mg/kg body weight). LSPH was obtained from LCS protein isolate via pancreatin hydrolysis. Thirty albino rats were grouped into six (6): Normal Control group (NC), Diabetic Control group (DC), 5 mg/kg body weight metformin, and 50, 100, and 150 mg/kg body weight (bwt) LSPH, respectively designated groups A - F. Proximate analysis of LCS revealed 28.17 % protein, 7.97 % fibre, 7.03 % ash, 7.98 % moisture, 43.25 % carbohydrate, and 5.60 % lipids. After hydrolysis, the protein isolate had 30.40 % protein content and 10.09 % peptide yield. After administering LSPH for 7 days, blood glucose significantly (p &lt; 0.05) decreased, compared to DC; group E (100 mg/kg bwt) demonstrated the highest reduction. Compared to DC, the enzyme activities (ALT, AST, ALP) in kidney and liver increased significantly (p &lt; 0.05), and the lipid profiles (TC, TRIG, HDL, LDL-C) in the serum reduced significantly (p &lt; 0.05). The levels of albumin, urea and creatinine were reduced significantly (p &lt; 0.05), while, compared to DC, the levels of serum bilirubin and protein increased. Compared to DC, malondialdehyde levels decreased, and antioxidant enzymes (CAT, SOD) levels increased significantly (p &lt; 0.05). This study revealed that LSPH may be explored as a potential anti-diabetic agent with little or no safety concern.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"28 ","pages":"Article e02629"},"PeriodicalIF":2.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143610821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel efficient estimators of finite population mean in simple random sampling","authors":"Khazan Sher ,&nbsp;Muhammad Iqbal ,&nbsp;Hameed Ali ,&nbsp;Soofia Iftikhar ,&nbsp;Maggie Aphane ,&nbsp;Ahmed Audu","doi":"10.1016/j.sciaf.2025.e02598","DOIUrl":"10.1016/j.sciaf.2025.e02598","url":null,"abstract":"<div><div>This study presents a methodological advancement in survey sampling, focusing on the development of efficient estimators for the finite population mean under Simple Random Sampling without Replacement (SRSWOR). By harnessing the predictive power of correlated auxiliary variables, we formulate two innovative classes of estimators that integrate supplementary data to improve estimation accuracy. A rigorous theoretical examination is conducted, deriving first-order bias and Mean Square Error (MSE) expressions to elucidate the estimators' properties. A comprehensive evaluation framework is employed, utilizing Percentage Relative Efficiency (PRE) to assess the performance of the proposed estimators in relation to existing methods. The findings, supported by empirical analyses given in Table 3 and Figure 1 and simulation studies shown in Table 4 and Figure 2, demonstrate the superiority of the proposed estimators <em>(</em><span><math><msub><mover><mi>y</mi><mo>¯</mo></mover><mrow><mi>P</mi><mi>r</mi><mi>o</mi><mn>1</mn></mrow></msub></math></span><em>,</em> <span><math><msub><mover><mi>y</mi><mo>¯</mo></mover><mrow><mi>P</mi><mi>r</mi><mi>o</mi><mn>2</mn></mrow></msub></math></span><em>)</em>, under specific conditions, contributing to the enhancement of survey sampling methodology.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"27 ","pages":"Article e02598"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental and numerical analysis of a reactor for plastic waste conversion and performance evaluation of pyrolytic fuel blend with diesel in a 1.6 HDi engine","authors":"Jamal Oufkir ,&nbsp;Soumaya Ounacer ,&nbsp;Rachid Cherouaki ,&nbsp;Said Belaaouad","doi":"10.1016/j.sciaf.2025.e02595","DOIUrl":"10.1016/j.sciaf.2025.e02595","url":null,"abstract":"<div><div>This study examines the potential of fuel obtained through pyrolysis of plastic waste as a substitute for traditional diesel in powering diesel engines. For this purpose, reactor optimization was conducted through Finite Element Analysis (FEA) using ANSYS software, minimizing thermal stresses and deformations, thus ensuring the resistance and stability of the pyrolysis unit materials at high temperatures. A maximum yield of 74.3 % by weight of Crude Pyrolytic Oil (CPO) was achieved at temperatures of 380 °C and 390 °C. FT-IR and GC–MS analyses revealed that CPO oil primarily consists of aliphatic hydrocarbons and aromatic compounds, with carbon chains ranging from C₈ to C₂₈. After filtration and purification of the CPO oil, the PPFO10 blend, consisting of 10 % pyrolytic oil and 90 % diesel, was tested on a 1.6HDi diesel engine installed in a vehicle. The performance and emissions of this blend were contrasted with those of pure diesel. The findings indicated that the PPFO10 blend exhibited performance almost equivalent to that of pure diesel. Full-load tests indicated slightly reduced CO₂ emissions, while CO, UHC, and NO_x emissions were slightly increased with the PPFO10 blend. However, the study concludes that the utilization of pyrolytic oil as a substitute for diesel holds promising potential for reducing fossil resource depletion.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"27 ","pages":"Article e02595"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valorization of date palm residues for biochar production: Assessing biochar characteristics for agricultural application","authors":"Mariyem Rehali ,&nbsp;Naïma El Ghachtouli ,&nbsp;Sébastien F. Lange ,&nbsp;Rachid Bouamri","doi":"10.1016/j.sciaf.2025.e02599","DOIUrl":"10.1016/j.sciaf.2025.e02599","url":null,"abstract":"<div><div>Date palm residues are abundant in many arid and semi-arid regions, presenting both an environmental challenge and an opportunity for sustainable resource management. This study evaluates the valorization of date palm residues through slow pyrolysis at 500 °C to produce biochar suitable for agricultural soil enhancement. The date palm residues, which consist of 41.95% cellulose, 28.49% hemicellulose, and 26.56% lignin, were processed to yield biochar with a production efficiency of 44.95%. The biochar's physicochemical properties were extensively analyzed, showing a fixed carbon content of 70.74%, a pH of 9.19, and a cation exchange capacity (CEC) of 68.05 cmol/kg. Elemental analysis revealed high carbon (71.9%) and low nitrogen (0.74%) content, indicating its stability and potential for long-term carbon sequestration. Thermogravimetric analysis (TGA) indicated thermal stability, while scanning electron microscopy (SEM) revealed a highly porous structure, beneficial for water retention and microbial colonization. These findings demonstrate that the slow pyrolysis process yields biochar with favorable properties, making it a promising amendment for soil fertilization. This study highlights the potential of biochar production in transforming date palm waste into valuable resources while mitigating the environmental impacts and costs associated with its disposal.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"27 ","pages":"Article e02599"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vivo anti-inflammatory activity, acute toxicity profiling, and sub-acute toxicity profiling of extracts from the fruit pulp and seeds of african baobab (Adansonia digitata L.)","authors":"Mercy Badu ,&nbsp;Philip T. Thompson ,&nbsp;Vivian E. Boamah","doi":"10.1016/j.sciaf.2025.e02615","DOIUrl":"10.1016/j.sciaf.2025.e02615","url":null,"abstract":"<div><div><em>Adansonia digitata</em> (L.) is an ancient plant widely known for its diverse medicinal properties. The pulp and seeds of this plant are commonly consumed by rural populations in Africa, valued for their poly-therapeutic benefits. This study investigates the anti-inflammatory activity, acute toxicity, and sub-acute toxicity of extracts from the pulp and seeds using animal models. The anti-inflammatory potential was assessed using a carrageenan-induced foot edema model in 7-day-old chicks, while the acute and sub-acute toxicities were evaluated in Wistar albino rats. In the anti-inflammatory study, the fruit pulp extract exhibited an ED₅₀ value of 282.12 mg/kg BW, while the seed extracts showed similar activity with ED₅₀ values of 338.41 mg/kg BW for the polar extract and 347.40 mg/kg BW for the non-polar extract. In the acute toxicity evaluation, no mortality was observed at the highest administered dose of 5000 mg/kg BW, suggesting an LD₅₀ value above the highest administered dose. Sub-acute toxicity studies over 28 days revealed significant increases (p &lt; 0.05) in body weight, absolute organ weight, and relative organ weight in rats, yet without adverse effects on hematological or biochemical parameters. Histopathological analysis confirmed the absence of damage to kidney and liver tissues, indicating the safety of the extracts at doses below the estimated LD₅₀. In conclusion, the extracts demonstrate notable anti-inflammatory activity and appear safe for consumption within the tested dose range, supporting their traditional use for health benefits.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"27 ","pages":"Article e02615"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unit exponentiated Weibull model with applications","authors":"Ammar M. Sarhan ,&nbsp;M.E. Sobh","doi":"10.1016/j.sciaf.2025.e02606","DOIUrl":"10.1016/j.sciaf.2025.e02606","url":null,"abstract":"<div><div>Developing new effective statistical distributions tailored to model data on the unit interval is essential in modern data analysis. In this article, we propose a novel distribution on the unit interval, termed the unit exponentiated Weibull distribution, derived from the three-parameter exponentiated Weibull distribution. We will explore the key statistical properties of this new distribution and employ the maximum likelihood and least squares methods for parameter estimation. A simulation study is conducted to evaluate the performance of the maximum likelihood and least squares estimates. The simulation study demonstrates that the maximum likelihood method outperforms the least squares method in estimating the three parameters of the underlying model. To illustrate the practical utility of the proposed model, we analyze real-world datasets and compare its performance against other established distributions. The results show that the proposed model provides a superior fit to the competing models considered in the study.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"27 ","pages":"Article e02606"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into the optoelectronic, quantum chemical, NBO and dynamic nonlinear optical properties of meso-BODIPY dyes","authors":"Oluwatoba Emmanuel Oyeneyin ,&nbsp;Nathanael Damilare Ojo ,&nbsp;Adesoji Alani Olanrewaju ,&nbsp;Blessing Lully Isaiah ,&nbsp;Nnenna Winifred Odozi ,&nbsp;Edmore Farayi Kangara ,&nbsp;Matshawandile Tukulula","doi":"10.1016/j.sciaf.2025.e02608","DOIUrl":"10.1016/j.sciaf.2025.e02608","url":null,"abstract":"<div><div>Herein, understanding the effect of substituents on the electronic absorption, optoelectronic, static and dynamic nonlinear optical (NLO) properties, and molecular stability of (CF₃-, CH₃-, CCl₃-, NH₂-, NO₂-) meso-substituted BODIPY dyes was specifically aimed at using density functional (B3LYP and CAM-B3LYP) approach with 6–311++G(d,p). Solvent perturbation of electronic excitation energy, oscillator strength and light-harvesting efficiency (LHE) was observed. The LHE increased from 74–80% in gas to 87–90% in acetonitrile. The static first-order and second-order (β, γ) NLO properties of the dyes were significantly greater than those of urea (a standard NLO material). Interestingly, the dynamic NLO [electro-optic Pockels effect: β(-ω;ω,0); second harmonic generation (SHG): β(-2ω;ω,ω); electro-optic Kerr effect: γ(-ω;ω,0,0); direct current SHG: γ(-2ω;ω,ω,0)] at <em>ħω</em> = 0.042823 au were greater than the static β and γ (<em>ħω</em> = 0). NO₂- substituted dye presented greatest NLO amplitudes. Natural bond orbital (NBO) analysis identified conjugative and hyperconjugative interactions as the major contributors to the structural stabilization of the dyes. Except for NO₂-dye, a negative free energy for electron injection and a positive open-circuit voltage were observed indicating good optoelectronic potential of the substituted BODIPY in dye sensitized solar cells. The molecular instability, chemical reactivity (from energy gap) and dynamic NLO response of the dyes increased in the order: NH₂- &lt; CH₃- &lt; CF₃- &lt; CCl₃ &lt; NO₂-.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"27 ","pages":"Article e02608"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Huff’s form for elliptic curves over a local ring","authors":"Abdelhakim Chillali ,&nbsp;Moha Ben Taleb El Hamam ,&nbsp;Abdelâli Grini","doi":"10.1016/j.sciaf.2025.e02597","DOIUrl":"10.1016/j.sciaf.2025.e02597","url":null,"abstract":"<div><div>Let <span><math><msub><mrow><mi>F</mi></mrow><mrow><mi>q</mi></mrow></msub></math></span> be a finite field of order <span><math><mrow><mi>q</mi><mo>=</mo><msup><mrow><mi>p</mi></mrow><mrow><mi>c</mi></mrow></msup></mrow></math></span>, where <span><math><mi>p</mi></math></span> is a prime number <span><math><mrow><mo>≥</mo><mn>3</mn></mrow></math></span>, <span><math><mrow><mi>c</mi><mo>∈</mo><msup><mrow><mi>N</mi></mrow><mrow><mo>∗</mo></mrow></msup></mrow></math></span>. In this paper, we introduce Huff curves denoted <span><math><msubsup><mrow><mi>H</mi></mrow><mrow><mi>a</mi><mo>,</mo><mi>b</mi></mrow><mrow><mn>2</mn></mrow></msubsup></math></span> over the local ring <span><math><mrow><msub><mrow><mi>R</mi></mrow><mrow><mn>2</mn></mrow></msub><mo>=</mo><msub><mrow><mi>F</mi></mrow><mrow><mi>q</mi></mrow></msub><mrow><mo>[</mo><mi>X</mi><mo>]</mo></mrow><mo>/</mo><mrow><mo>(</mo><msup><mrow><mi>X</mi></mrow><mrow><mn>2</mn></mrow></msup><mo>)</mo></mrow></mrow></math></span>. At first, we recall the arithmetic of the ring <span><math><msub><mrow><mi>R</mi></mrow><mrow><mn>2</mn></mrow></msub></math></span>. After that, we define Huff curves <span><math><msubsup><mrow><mi>H</mi></mrow><mrow><mi>a</mi><mo>,</mo><mi>b</mi></mrow><mrow><mn>2</mn></mrow></msubsup></math></span> over this ring and we study the group <span><math><msubsup><mrow><mi>H</mi></mrow><mrow><mi>a</mi><mo>,</mo><mi>b</mi></mrow><mrow><mn>2</mn></mrow></msubsup></math></span>, its properties and the classification of its elements. Precisely, we give a bijection between the groups <span><math><msubsup><mrow><mi>H</mi></mrow><mrow><mi>a</mi><mo>,</mo><mi>b</mi></mrow><mrow><mn>2</mn></mrow></msubsup></math></span> and <span><math><mrow><msub><mrow><mi>H</mi></mrow><mrow><msub><mrow><mi>a</mi></mrow><mrow><mn>0</mn></mrow></msub><mo>,</mo><msub><mrow><mi>b</mi></mrow><mrow><mn>0</mn></mrow></msub></mrow></msub><mo>×</mo><msub><mrow><mi>F</mi></mrow><mrow><mi>q</mi></mrow></msub></mrow></math></span>, where <span><math><msub><mrow><mi>H</mi></mrow><mrow><msub><mrow><mi>a</mi></mrow><mrow><mn>0</mn></mrow></msub><mo>,</mo><msub><mrow><mi>b</mi></mrow><mrow><mn>0</mn></mrow></msub></mrow></msub></math></span> is the Huff curves over the finite field <span><math><msub><mrow><mi>F</mi></mrow><mrow><mi>q</mi></mrow></msub></math></span>.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"27 ","pages":"Article e02597"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A bibliometric analysis on renewable energy microgrids integrating hydrogen storage: Strategies for optimal sizing and energy management","authors":"Mukhtar Fatihu Hamza ,&nbsp;Babangida Modu","doi":"10.1016/j.sciaf.2025.e02609","DOIUrl":"10.1016/j.sciaf.2025.e02609","url":null,"abstract":"<div><div>Hydrogen is regarded as a viable alternative energy carrier because of its superior energy density and low emissions, with great potential for decarbonizing multiple sectors and improving energy sustainability by integrating into the existing energy systems and renewable energy source within the utility. This paper provides a bibliometric assessment through an extensive review of highly cited articles on hydrogen storage integrated microgrid. The study utilized the Web of Science (WoS) database to look for specific keywords related to hydrogen storage integrated microgrid and associated research. The findings reveal that optimization, highly positioned and connected to many other keywords, is demonstrating its importance in the research area. Notable insights highlight the dominance of simulation-based studies, a significant number of publications in top-tier journals, and the rise of innovative research fields, including the creation of sustainable electrodes and improvements in system reliability and efficiency. The evaluation of the articles that are highly cited sheds light on diverse elements, such as approach and system, challenges, and research spaces. This analysis shows ways to improve the performance of operation, energy efficiency, environmental sustainability, cost-effectiveness, stable supply of power, on-location energy generation, and flexibility, thereby advancing technological innovation and fostering the development of hydrogen storage-integrated microgrids.</div></div>","PeriodicalId":21690,"journal":{"name":"Scientific African","volume":"27 ","pages":"Article e02609"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}