Science of Advanced Materials最新文献_第8页

Green Synthesis of Therapeutically Active Heterocyclic Scaffolds: A Review 治疗活性杂环支架的绿色合成研究进展

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-06-01 DOI: 10.1166/sam.2023.4477

Tasneem Mohammed, A. Nasreen, Yahya S. Alqahtani, I. Shaikh, S. Iqubal, Shaik Honey Fathima, A. Khan

{"title":"Green Synthesis of Therapeutically Active Heterocyclic Scaffolds: A Review","authors":"Tasneem Mohammed, A. Nasreen, Yahya S. Alqahtani, I. Shaikh, S. Iqubal, Shaik Honey Fathima, A. Khan","doi":"10.1166/sam.2023.4477","DOIUrl":"https://doi.org/10.1166/sam.2023.4477","url":null,"abstract":"Green chemistry lowers chemical hazards during chemical design, manufacture, and use. By using cleaner solvents, catalysts, and reaction conditions, this technique reduces environmental pollution and boosts atom economy and energy efficiency. Rapid industrialization and urbanization\u0000 are causing significant harm to our environment by releasing a lot of dangerous and undesired chemicals, gases, or other pollutants. The secrets hidden in nature and its by-products must now be discovered by us in order to enhance the synthesis of physiologically significant moieties and foster\u0000 its growth. Heterocyclic compounds and its derivatives exhibit various biological potential like anticancer, antimicrobial, anticonvulsant, analgesic, antitubercular, antiinflammatory and cardiovascular activities. This make them good candidates for future medication discovery and give them\u0000 the potential to be an arsenal for treating diseases. This article provides an overview of the numerous environmentally friendly and green synthetic techniques used to create diverse physiologically significant heterocyclic scaffolds in the period 2002–2022. It is anticipated that this\u0000 compilation of pertinent information will be of significance and practical value to chemists specializing in organic and pharmaceutical domains, potentially stimulating additional advancements in reaction development within this captivating area of study.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46655797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Damage Time-Dependent Characteristics and Failure Mechanism of Limestone with Different Mineral Compositions Under Acid Hydro-Chemical Solution Erosion 不同矿物成分石灰石在酸性水化学溶液侵蚀下的损伤时效特征及破坏机制

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-06-01 DOI: 10.1166/sam.2023.4419

Y. Yan, W. Ding, Guojiang Liu, Hongyi Wang, Tengyu Ma

{"title":"Damage Time-Dependent Characteristics and Failure Mechanism of Limestone with Different Mineral Compositions Under Acid Hydro-Chemical Solution Erosion","authors":"Y. Yan, W. Ding, Guojiang Liu, Hongyi Wang, Tengyu Ma","doi":"10.1166/sam.2023.4419","DOIUrl":"https://doi.org/10.1166/sam.2023.4419","url":null,"abstract":"Taking two types of limestone with different mineral compositions as research objects, we conducted experiments on the mass, longitudinal wave velocity, ion concentration of solution, fracture morphology, and micromorphology of two types of limestone specimens eroded by acidic hydro-chemical\u0000 solution. We investigated specimens’ damage time-dependent physical properties, dissolution, structure, discussing mineral composition effects and destruction. Results show that the mass loss rate of two types of limestone specimens eroded by acidic hydro-chemical solution increases\u0000 with the increase of immersion time in a power function, and the longitudinal wave velocity decreases and then fluctuates in a small range. The specimen fracture degree increases with the increase of the immersion time, and the rock micro-structure changes from dense and uniform into loose\u0000 and porous. The mass, the longitudinal wave velocity, the fracturing morphology, and damage to microscopic morphology of specimens increase with the increase of solution ion concentration. The acid rock reaction rate of limestone A is lower than that of limestone B, while the hydrolysis reaction\u0000 rate is higher. The mass loss rate, the longitudinal wave velocity loss rate, the ion concentration, and the damage degree of the macro-and micro-structure of limestone A are higher than that of limestone B.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43365240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insulin-Like Growth Factor 1: A Promoter of Proliferation and Metastasis in Papillary Thyroid Carcinoma Cells 胰岛素样生长因子1：甲状腺乳头状癌细胞增殖和转移的启动子

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-06-01 DOI: 10.1166/sam.2023.4490

P. He, Yi Zhang

引用次数: 0

Carbon Nanotubes/Gold Nanoclusters Based “Turn on” FRET Fluorescent Assay for miRNA Detection 基于碳纳米管/金纳米团簇的FRET荧光检测miRNA

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-06-01 DOI: 10.1166/sam.2023.4482

Lili Chen, Lingling Chen, Qiuhua Yang, Fengrong Zhang, Q. Qu

引用次数: 1

Study on Adsorption of Phosphate in Water Environment by Mg–Al Modified Biochar 镁铝改性生物炭对水环境中磷酸盐的吸附研究

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-06-01 DOI: 10.1166/sam.2023.4479

Dan Yang, Shou-Kun Chen, Chengtao Xu, Zhou Zhou

{"title":"Study on Adsorption of Phosphate in Water Environment by Mg–Al Modified Biochar","authors":"Dan Yang, Shou-Kun Chen, Chengtao Xu, Zhou Zhou","doi":"10.1166/sam.2023.4479","DOIUrl":"https://doi.org/10.1166/sam.2023.4479","url":null,"abstract":"Excessive release of phosphate has gained prominence as a pivotal contributor to water contamination. Biochar, known for its abundant surface acreage and unparalleled adsorptive prowess, has been widely employed in aqueous remediation. Within the scope of this investigation, unprocessed\u0000 biochar was derived from Chaetomorpha valida via pyrolysis methodologies involving temperatures ranging from 320 °C, 460 °C, 620 °C, and 860 °C, respectively. Mg-BC620, Al-BC620, and Mg–Al-BC620 were prepared using the co-precipitation\u0000 method at the optimal temperature to maximize the resource utilization of Chaetomorpha valida. The physicochemical attributes of altered biochars were evaluated employing X-ray diffractometry and other analytical techniques. The influence of different factors on phosphate’s adsorptive\u0000 aptitude of altered biochar was investigated, and the adsorptive behavior and mechanism of biochar were studied using diverse kinetics of adsorption and assortment of isotherm models. The outcomes revealed that the optimal pyrolysis temperature was 620 °C, and the altered biochar displayed\u0000 a strikingly elevated affinity for phosphate sorption, outperforming the unaltered biochar. Among the modified biochars, Mg–Al-BC620 outperformed the rest, boasting an astonishing eradication rate of 94.92% when dosed at 8 g/L, maintaining a pH equilibrium of 7 in the solution,\u0000 while confronting an inceptive phosphate density of 150 mg/L. The utmost threshold of adsorption proficiency predicted by the Langmuir equation was 228.130 mg/g, which was 88.56 times that of BC620. This modified biochar exhibits a strong affinity for phosphate and excellent adsorption\u0000 selectivity, providing a promising avenue for the resource utilization of Chaetomorpha valida and has broad application prospects for scavenging phosphate in aqueous mediums.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49084988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Tin Oxide-Graphene Oxide (SnO2/GO) Nanocomposite: A Promising Photocatalyst for Rhodamine-B Dye Degradation 氧化锡-氧化石墨烯（SnO2/GO）纳米复合材料：一种有前途的降解罗丹明-B染料的光催化剂

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-05-01 DOI: 10.1166/sam.2023.4465

M. B. R. Kamalam, J. Menaka, S. S. R. Inbanathan, K. Sethuraman, A. Shahid, H. Fouad, S. Hussain

{"title":"Tin Oxide-Graphene Oxide (SnO2/GO) Nanocomposite: A Promising Photocatalyst for Rhodamine-B Dye Degradation","authors":"M. B. R. Kamalam, J. Menaka, S. S. R. Inbanathan, K. Sethuraman, A. Shahid, H. Fouad, S. Hussain","doi":"10.1166/sam.2023.4465","DOIUrl":"https://doi.org/10.1166/sam.2023.4465","url":null,"abstract":"Appropriate wastewater treatment methods for effectual and practical decontamination of wastewater bodies is the prime goal of today’s environmentalists and industrialists. Herein, sunlight driven photocatalytic degradation of rhodamine-B (RhB) has been investigated by employing\u0000 hydrothermally synthesized tin oxide-graphene oxide (SnO2/GO) nanocomposite. Physiochemical characterization of composite has been accomplished via X-ray diffraction (XRD) analysis, ultraviolet (UV) spectroscopy, diffused reflectance spectroscopy (DRS) and photoluminescence (PL).\u0000 Photocatalytic degradation of RhB is studied using UV light and spectrophotometer. SnO2-GO nanocomposite degraded the RhB dye in 120 min comparatively in quite lesser time than separate SnO2 and GO degradation performances. The incorporation of GO into SnO2\u0000 decreases the rate of electron–hole recombination, increases the oxidation of carriers as well as the rate of carrier separation owing to the synergistic impact of GO and SnO2. Therefore, an affordable graphene oxide supported SnO2 nanocomposite can be implicated\u0000 as efficacious real wastewater treatment method at industrial scale.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43522064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green Synthesis of Silver Nanoparticles from Solenostemma argel Leaf Extract: Characterization and Wound Healing Activity 绿色合成银纳米粒子的扶桑叶提取物:表征和伤口愈合活性

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-05-01 DOI: 10.1166/sam.2023.4472

M. Ahmad, J. Ahmad, Basel A. Abdel-Wahab, Ali S. Alasiri, H. F. Alotaibi, Abdulhakeem Mohammed Saeed, F. A. Mahboob, Osman A. E. Elnoubi, S. Wahab, Zufesha NoorulHuda Khan

{"title":"Green Synthesis of Silver Nanoparticles from Solenostemma argel Leaf Extract: Characterization and Wound Healing Activity","authors":"M. Ahmad, J. Ahmad, Basel A. Abdel-Wahab, Ali S. Alasiri, H. F. Alotaibi, Abdulhakeem Mohammed Saeed, F. A. Mahboob, Osman A. E. Elnoubi, S. Wahab, Zufesha NoorulHuda Khan","doi":"10.1166/sam.2023.4472","DOIUrl":"https://doi.org/10.1166/sam.2023.4472","url":null,"abstract":"Green synthesis or biosynthesis of nanoparticles (NPs) has recently emerged as a significant approach to producing metallic NPs due to its rapid, affordable and ease of fabrication. Silver nanoparticles (AgNPs) are particularly impressive due to their antimicrobial, bacteriostatic,\u0000 and low in vivo toxicity. Wound healing is a complex procedure involving the activity of various tissues and cell lineages that have long been the topic of intense research. A faster and more efficient recovery with the minimum side effects is one of the key goals in wound healing.\u0000 The current study aims to perform a green synthesis of AgNPs mediated by Solenostemma argel leaf extract, combine it with chitosan (CS) gel, and evaluate its effectiveness as a wound healing agent in a rat model. The biosynthesized AgNPs were characterized by UV-visible spectroscopy,\u0000 FTIR, XRD, DLS analysis and SEM imaging. The developed AgNPs were spherical, with sizes ranging from 60–90 nm. Analysis of the UV-visible spectrum revealed a strong peak at 418.02 nm; this was the first indication of the biosynthesis of AgNPs. X-Ray diffraction analysis indicated the\u0000 crystallinity phase of biosynthesized AgNPs. The mean hydrodynamic diameter and PDI of the biosynthesized AgNPs were 71.38±2.73 nm and 0.208±0.01, respectively. A high negative zeta potential (30.95±0.58 mV) indicates that the nanomaterial is highly stabilized. The developed\u0000 AgNPs were uniformly dispersed with 2% w/v CS solution to form AgNPs/CS gel. The in-vivo animal experiment and histopathological analysis outcomes revealed that groups of wounded animals receiving the topical application of AgNPs/CS-gel experienced quicker and better wound healing.\u0000 Based on this outcome, it can be concluded that biosynthesized AgNPs developed into AgNPs/CS-gel have great potential to be established as wound healing agents.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48951717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Long Non-Coding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1: Epigenetic Regulation of PTEN in Mediating Vascular Smooth Muscle Cell Proliferation and Apoptosis 长链非编码RNA转移相关肺腺癌转录物1:PTEN介导血管平滑肌细胞增殖和凋亡的表观遗传调控

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-05-01 DOI: 10.1166/sam.2023.4485

Anas O. K. Abu Bokha, Mingyang Song, Chen-He Li, Ahmad M. Zalloom, Rui Li

{"title":"Long Non-Coding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1: Epigenetic Regulation of PTEN in Mediating Vascular Smooth Muscle Cell Proliferation and Apoptosis","authors":"Anas O. K. Abu Bokha, Mingyang Song, Chen-He Li, Ahmad M. Zalloom, Rui Li","doi":"10.1166/sam.2023.4485","DOIUrl":"https://doi.org/10.1166/sam.2023.4485","url":null,"abstract":"This study investigated the regulatory role of long non-coding RNA (lncRNA) MALAT1 in HA-VSMCs proliferation and apoptosis through mediating PTEN level. HA-VSMCs were induced with different doses of ox-LDL for various time points, and the relative level of MALAT1 was determined. MALAT1\u0000 was upregulated in a time- and dose-dependent manner. Overexpression of MALAT1 increased viability and proliferative rate, and decreased apoptotic rate of HA-VSMCs induced with 100 mg/L ox-LDL for 24 h, which was reversed by si-MALAT1 transfection. PTEN protein level was downregulated by ox-LDL\u0000 induction and upregulated by si-MALAT1. MALAT1 was mainly distributed in the nucleus, and it interacted with EZH2. Silencing of MALAT1 attenuated EZH2 binding on PTEN promoter region. Knockdown of PTEN reversed the decreased proliferative ability and increased apoptotic rate in ox-LDL-induced\u0000 HA-VSMCs transfected with si-MALAT1. These results indicate that MALAT1 accelerates HA-VSMCs proliferation by recruiting EZH2 to mediate PTEN level. Overall, MALAT1 may play a crucial role in the progression of atherosclerosis and may be a potential therapeutic target.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47957639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural Stiffness and Mechanical Analysis of Fiber Wound Composite Sports Equipment Reinforced with Carbon Fiber Materials 碳纤维增强纤维缠绕复合材料运动器材的结构刚度与力学分析

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-05-01 DOI: 10.1166/sam.2023.4469

Jian Guo

引用次数: 1

Influence of Oxygen Adsorption on Local N-Doped TiO2/p-Si (100) Heterojunction UV-Visible Photodetector 氧吸附对局部n掺杂TiO2/p-Si(100)异质结紫外-可见光探测器的影响

IF 0.9 4区材料科学

Science of Advanced Materials Pub Date : 2023-05-01 DOI: 10.1166/sam.2023.4467

G. Tian, Qiumei Lei, Wenyao Li, Anna Su, M. Hashem, Tao Ji

{"title":"Influence of Oxygen Adsorption on Local N-Doped TiO2/p-Si (100) Heterojunction UV-Visible Photodetector","authors":"G. Tian, Qiumei Lei, Wenyao Li, Anna Su, M. Hashem, Tao Ji","doi":"10.1166/sam.2023.4467","DOIUrl":"https://doi.org/10.1166/sam.2023.4467","url":null,"abstract":"TiO2-based devices are known for their responsive behavior to environmental conditions. In this study, we report the fabrication of a locally N-doped TiO2/p-Si (100) heterojunction UV-vis photodetector, achieved through a series of processes including magnetron\u0000 sputtering, high-temperature annealing, hydrothermal synthesis, and thermal evaporation. Due to surface oxygen adsorption and partial nitrogen doping in TiO2, the photocurrent of the device was found to be higher in vacuum than in air at low voltage, and lower in vacuum than in\u0000 air at higher voltage. Moreover, the photocurrent was more likely to reach saturation under vacuum at low voltage. Under UV light illumination (380 nm), the voltage applied to the device to reach the saturation currents in vacuum and air were approximately −1 V and −1.5 V, respectively,\u0000 and these values increased slightly when illuminated by visible light (480 nm). The study of the impact of oxygen adsorption and partial N doping in TiO2 on the hindrance and multiplier effects of carrier movement in photodetectors can be beneficial for the development and application\u0000 of wearable, biosensing, and vacuum sensing devices.","PeriodicalId":21671,"journal":{"name":"Science of Advanced Materials","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46066478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0