Seminars in reproductive medicine最新文献_第2页

Helping Patients to Predict and Confirm Ovulation with the Use of Combined Urinary Hormonal and Smartphone Technology: A Proof-of-Concept Retrospective Descriptive Case Series. 利用尿液荷尔蒙和智能手机技术帮助患者预测和确认排卵：概念验证回顾性描述性病例系列。

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-06-01 Epub Date: 2024-10-08 DOI: 10.1055/s-0044-1791702

Rene Leiva, Rene Ecochard

{"title":"Helping Patients to Predict and Confirm Ovulation with the Use of Combined Urinary Hormonal and Smartphone Technology: A Proof-of-Concept Retrospective Descriptive Case Series.","authors":"Rene Leiva, Rene Ecochard","doi":"10.1055/s-0044-1791702","DOIUrl":"10.1055/s-0044-1791702","url":null,"abstract":"Smartphone-based fertility awareness methods with home-based urinary hormonal testing are gaining popularity for fertility tracking. In our university-affiliated family practice, we integrated a previously developed ovulation tracking application into a protocol for monitoring urinary sex hormones and cervical secretions. Serum progesterone was used to confirm the luteal phase, with levels ≥ 15.9 nmol/L ensuring confirmation. Data from 110 women seen for infertility treatment (n = 95) or family planning advice (n = 15) and using our ovulation prediction protocol showed that most opted for a combination of cervical mucus and luteinizing hormone testing (n = 86). Among those using it for family planning, the median usage among women spanned 56 cycles, and 13 cycles per woman required progesterone testing for confirmation. Thirteen patients are still using the method without unintended pregnancies. No unintended pregnancies occurred. Confidence in tests based on serum progesterone was high (93%). For infertility, the method helped in the identification of anovulation, evaluating treatment response, and in diagnosing subfertility causes. This proof-of-concept retrospective descriptive case series suggests the potential for smartphone-based monitoring in fertility management, urging further studies for application enhancements and prospective validation.","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":" ","pages":"90-99"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11581822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient-Centric In Vitro Fertilization Prognostic Counseling Using Machine Learning for the Pragmatist. 为实用主义者提供以患者为中心的体外受精预后咨询（使用机器学习）。

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-06-01 Epub Date: 2024-10-08 DOI: 10.1055/s-0044-1791536

Mylene W M Yao, Julian Jenkins, Elizabeth T Nguyen, Trevor Swanson, Marco Menabrito

{"title":"Patient-Centric In Vitro Fertilization Prognostic Counseling Using Machine Learning for the Pragmatist.","authors":"Mylene W M Yao, Julian Jenkins, Elizabeth T Nguyen, Trevor Swanson, Marco Menabrito","doi":"10.1055/s-0044-1791536","DOIUrl":"10.1055/s-0044-1791536","url":null,"abstract":"Although in vitro fertilization (IVF) has become an extremely effective treatment option for infertility, there is significant underutilization of IVF by patients who could benefit from such treatment. In order for patients to choose to consider IVF treatment when appropriate, it is critical for them to be provided with an accurate, understandable IVF prognosis. Machine learning (ML) can meet the challenge of personalized prognostication based on data available prior to treatment. The development, validation, and deployment of ML prognostic models and related patient counseling report delivery require specialized human and platform expertise. This review article takes a pragmatic approach to review relevant reports of IVF prognostic models and draws from extensive experience meeting patients' and providers' needs with the development of data and model pipelines to implement validated ML models at scale, at the point-of-care. Requirements of using ML-based IVF prognostics at point-of-care will be considered alongside clinical ML implementation factors critical for success. Finally, we discuss health, social, and economic objectives that may be achieved by leveraging combined human expertise and ML prognostics to expand fertility care access and advance health and social good.","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":" ","pages":"112-129"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11581823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding the Strengths and Limitations of Online Oocyte Cryopreservation Calculators. 了解在线卵母细胞冷冻保存计算器的优势和局限性。

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-06-01 Epub Date: 2024-07-10 DOI: 10.1055/s-0044-1788030

Amber T Wolf, Evelyn Minis, Shruthi Mahalingaiah

{"title":"Understanding the Strengths and Limitations of Online Oocyte Cryopreservation Calculators.","authors":"Amber T Wolf, Evelyn Minis, Shruthi Mahalingaiah","doi":"10.1055/s-0044-1788030","DOIUrl":"10.1055/s-0044-1788030","url":null,"abstract":"Between 2010 and 2016, elective oocyte cryopreservation (OC) increased in use by 880% in the United States; however, there have been increasing reports of regret among patients after elective OC. There is a growing need for individualized counseling on the timing and number of oocytes to cryopreserve for patients to make informed choices and set realistic expectations, but currently available tools seem to be insufficient. The purpose of this review is to describe the OC calculators currently available online, identify sources of regret, and illustrate the need for unified counseling tools for improved patient care and education. OC calculators were identified via Google search. Only calculators that cite scientific literature were included in the review. Calculators for in vitro fertilization or embryo transfer were excluded. Thirteen OC calculators were found; however, only six cited literature supporting the calculator's design. When entering the same hypothetical patient parameters for age and number of oocytes cryopreserved, the calculators provided drastically different probabilities of live births. The lack of cohesive online educational materials creates confusion and stress for patients considering OC, leading to unrealistic expectations and increased feelings of regret thereafter. Physicians need tools to provide comprehensive guidance to patients seeking to cryopreserve oocytes.","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":" ","pages":"130-139"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141580755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Connecting the Dots on Female Digital Health Education: A Systematic Review. 连接女性数字健康教育的点点滴滴：系统回顾。

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-06-01 Epub Date: 2024-10-11 DOI: 10.1055/s-0044-1791535

Carol Johnson, Barbara Tafuto

{"title":"Connecting the Dots on Female Digital Health Education: A Systematic Review.","authors":"Carol Johnson, Barbara Tafuto","doi":"10.1055/s-0044-1791535","DOIUrl":"10.1055/s-0044-1791535","url":null,"abstract":"Identified barriers to care for common, chronic conditions that impact millions of females suggest that patient education is critical to improving the care experience, expediting a diagnosis, and elevating outcomes. This article aims to understand the efficacy of digital patient education interventions on patient outcomes, specifically those addressing common causes of chronic abnormal uterine bleeding, premenstrual dysphoric disorder, and endometriosis. We queried MEDLINE, PubMed, Cochrane Library, and Google Scholar for articles published in English between January 1, 2014, and May 1, 2024, on digital patient education and urogenital diseases. The search identified 260 articles, 247 of which were retrieved for title and abstract review, 27 of which were retrieved for full-text review, and 25 of which were excluded. Two studies were included in this review. Both studies were individual-/community-level interventions involving digitally delivered patient education. Participants had received a diagnosis and were engaged in accessing care when enrolled, and each study was conducted at a single site. Both interventions produced positive results. Despite the potential of digital health education to improve patient outcomes, limited research in this field underscores the need for further studies to validate interventions and address gaps in knowledge.","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":" ","pages":"151-162"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142406775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How the Menstrual Cycle Can Be Utilized During Sports Training, Performance, and Recovery through Wearable Technology: A Narrative Review for Researchers, Physicians, Coaches, and Athletes. 如何通过可穿戴技术在体育训练、表现和恢复期间利用月经周期：面向研究人员、医生、教练和运动员的叙述性综述》。

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-06-01 Epub Date: 2024-10-18 DOI: 10.1055/s-0044-1791508

Naiomi Nhen Hunter, Morgan A Smith

{"title":"How the Menstrual Cycle Can Be Utilized During Sports Training, Performance, and Recovery through Wearable Technology: A Narrative Review for Researchers, Physicians, Coaches, and Athletes.","authors":"Naiomi Nhen Hunter, Morgan A Smith","doi":"10.1055/s-0044-1791508","DOIUrl":"10.1055/s-0044-1791508","url":null,"abstract":"The menstrual cycle (MC) serves as a vital indicator of overall health and metabolic function, regulated by the hypothalamic-pituitary axis and involving a complex interplay of hormones. Understanding these hormonal dynamics is crucial for deciphering an individual's physiological status and performance potential, particularly in athletes. Studies regarding the MC's impact on athletic performance and training often lack inclusivity, standardized methodologies, and inconsistent biological definitions, hindering comprehensive conclusions. Moreover, societal inequalities contribute to the underrepresentation of female athletes in research, exacerbating the lack of understanding regarding female physiology in sports medicine. Leveraging wearable technology presents a promising avenue for both tracking MCs and optimizing athletic training/recovery. Wearables offer real-time monitoring of biometrics that often correlate with hormonal fluctuations, and lifestyle trends (diet, sleep, stress) aiding in personalized training schedules and performance optimization. Integrating data collected by MC dynamics and wearable technology into athletic training has the potential to decrease the generally perceived negative impacts MC has on athletic performance. Addressing gaps in research methodologies and promoting awareness among athletes, coaches, and healthcare professionals are essential steps toward maximizing the potential of MC-informed training strategies.","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":" ","pages":"73-80"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovative Approaches to Digital Health in Ovulation Detection: A Review of Current Methods and Emerging Technologies. 排卵检测中的数字健康创新方法：当前方法和新兴技术综述》。

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-06-01 Epub Date: 2024-11-21 DOI: 10.1055/s-0044-1793829

Katerina Shkodzik

{"title":"Innovative Approaches to Digital Health in Ovulation Detection: A Review of Current Methods and Emerging Technologies.","authors":"Katerina Shkodzik","doi":"10.1055/s-0044-1793829","DOIUrl":"https://doi.org/10.1055/s-0044-1793829","url":null,"abstract":"Ovulation is a vital sign, as significant as body temperature, heart rate, respiratory rate, and blood pressure, in assessing overall health and identifying potential health issues. Ovulation is a key event of the menstrual cycle that provides insights into the hormonal and reproductive health aspects. Affected by the orchestra of hormones, namely thyroid, prolactin, and androgens, disruptions in ovulation can indicate endocrinological conditions and lead to gynecological problems, such as heavy menstrual bleeding, irregular periods, amenorrhea, dysmenorrhea, and difficulties in getting pregnant. Monitoring ovulation and detecting disruptions can aid in the early detection of health issues, extending beyond reproductive health concerns. It can help identify underlying causes of symptoms like excessive fatigue and abnormal hair growth. The integration of digital health technologies, such as mobile apps using machine learning algorithms, wearables tracking temperature, heart rate, breath rate, and sleep patterns, and devices measuring reproductive hormones in urine or saliva samples, offers a wealth of opportunities in family planning, early health issue diagnosis, treatment adjustment, and tracking menstrual cycles during assisted reproductive techniques. These advancements provide a comprehensive approach to health monitoring, addressing both reproductive and overall health concerns.","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":"42 2","pages":"81-89"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Ovulation and Luteal Phase Tracking Methods and Technologies for Fertility and Family Planning: A Review. 当前用于生育和计划生育的排卵和黄体期跟踪方法与技术：综述。

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-06-01 Epub Date: 2024-09-20 DOI: 10.1055/s-0044-1791190

Andrea K Wegrzynowicz, Aimee Eyvazzadeh, Amy Beckley

{"title":"Current Ovulation and Luteal Phase Tracking Methods and Technologies for Fertility and Family Planning: A Review.","authors":"Andrea K Wegrzynowicz, Aimee Eyvazzadeh, Amy Beckley","doi":"10.1055/s-0044-1791190","DOIUrl":"10.1055/s-0044-1791190","url":null,"abstract":"Ovulation is critical for both conception and overall health, but many people who may ovulate are not tracking ovulation or any other part of their menstrual cycle. Failure to track ovulation, especially in those trying to conceive, can lead to fertility challenges due to absent ovulation, mistiming intercourse, or an undetected luteal phase defect. Ovulatory disorders and mistiming intercourse are both primary causes of infertility, and tracking ovulation is shown to decrease the average time to conception. While there are many tracking methods and apps available, the majority are predictive apps or ovulation predictor kits and do not test or track both successful ovulation and the health of the luteal phase, leading to missing information that could contribute to diagnosis or successful conception. Here, we review why ovulation tracking and a healthy luteal phase are important for those trying to conceive. We present currently available ovulation tracking methods that detect both ovulation and the luteal phase, including cervical mucus, urinary hormone testing, and basal body temperature, and discuss the use, advantages, and disadvantages of each. Finally, we consider the role of digital applications and tracking technologies in ovulation tracking.","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":" ","pages":"100-111"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Anti-Müllerian Hormone in the Central Regulation of Fertility 抗缪勒氏管激素在生育中枢调节中的作用

IF 2.7 3区医学

Seminars in reproductive medicine Pub Date : 2024-04-12 DOI: 10.1055/s-0044-1786050

Ludovica Cotellessa, Paolo Giacobini

{"title":"Role of Anti-Müllerian Hormone in the Central Regulation of Fertility","authors":"Ludovica Cotellessa, Paolo Giacobini","doi":"10.1055/s-0044-1786050","DOIUrl":"https://doi.org/10.1055/s-0044-1786050","url":null,"abstract":"In recent years, the expanding roles of anti-Müllerian hormone (AMH) in various aspects of reproductive health have attracted significant attention. Initially recognized for its classical role in male sexual differentiation, AMH is produced postnatally by the Sertoli cells in the male testes and by the granulosa cells in the female ovaries. Traditionally, it was believed to primarily influence gonadal development and function. However, research over the last decade has unveiled novel actions of AMH beyond the gonads, specifically all along the hypothalamic–pituitary–gonadal axis. This review will focus on the emerging roles of AMH within the hypothalamus and discusses its potential implications in reproductive physiology. Additionally, recent preclinical and clinical studies have suggested that elevated levels of AMH may disrupt the hypothalamic network regulating reproduction, which could contribute to the central pathophysiology of polycystic ovary syndrome. These findings underscore the intricate interplay between AMH and the neuroendocrine system, offering new avenues for understanding the mechanisms underlying fertility and reproductive disorders. ","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":"50 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140578771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utility of Serum Anti-Müllerian Hormone Measurement as Part of Polycystic Ovary Syndrome Diagnosis. 血清抗苗勒管激素测定作为多囊卵巢综合征诊断的一部分的实用性。

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-03-01 Epub Date: 2024-05-22 DOI: 10.1055/s-0044-1786731

Terhi T Piltonen, Johanna Viita-Aho, Ulla Saarela, Johanna Melin, Maria Forslund

{"title":"Utility of Serum Anti-Müllerian Hormone Measurement as Part of Polycystic Ovary Syndrome Diagnosis.","authors":"Terhi T Piltonen, Johanna Viita-Aho, Ulla Saarela, Johanna Melin, Maria Forslund","doi":"10.1055/s-0044-1786731","DOIUrl":"10.1055/s-0044-1786731","url":null,"abstract":"The 2023 international evidence-based guideline update for the assessment and management of polycystic ovary syndrome (PCOS) recommends using the Rotterdam criteria for the diagnosis of PCOS. The updated guideline has evidence-based recommendation for the diagnosis, and it now also includes serum anti-Müllerian hormone (AMH) measurement as an alternative tool for gynecological ultrasound to diagnose polycystic ovary morphology (PCOM). The aim of this new recommendation was to facilitate PCOS diagnostic workup in primary care and other disciplines, as currently most diagnosing is done in gynecology and infertility clinics. Here, we review factors affecting AMH levels as well as the utility of AMH in PCOS diagnosis. We identified relevant studies that report different cut-offs for AMH to diagnose PCOM as part of PCOS diagnosis. There are, however, some limitations when using AMH that should be acknowledged. These include physiological aspects like age, ethnicity, and obesity and iatrogenic causes like hormonal medication and ovarian surgery. Also reference ranges are different depending on AMH assay used. As a summary, we conclude that AMH is a usable tool in PCOM diagnostics, but it does not have a single cut-off. Therefore, further studies are needed to establish age and assay-based reference ranges.","PeriodicalId":21661,"journal":{"name":"Seminars in reproductive medicine","volume":" ","pages":"49-59"},"PeriodicalIF":1.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11257749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141082292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Anti-Müllerian Hormone in Ovarian Function. 抗缪勒氏管激素在卵巢功能中的作用

IF 1.9 3区医学

Seminars in reproductive medicine Pub Date : 2024-03-01 Epub Date: 2024-05-23 DOI: 10.1055/s-0044-1786732

Sena Yildiz, Loes M E Moolhuijsen, Jenny A Visser

引用次数: 0