Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology最新文献

{"title":"ALTERNATIVE NON-TRADITIONAL SOURCES OF FEED PROTEIN AND AMINO ACIDS","authors":"Н. P. Ryvak, T. R. Levitskyy, G. I. Boyko, G. Y. Nedilka, O. M. Vilha","doi":"10.36359/scivp.2024-25-1.19","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.19","url":null,"abstract":"The article presents a literature review on the risks of the global problem of fodder protein and protein amino acids in the feeding of agricultural animals and poultry. Alternative ways of solving it are due to the production and use of non-traditional feed raw materials in feed diets. A number of scientists consider atypical agricultural biotechnological products obtained from insects to be one of the alternative sources of fodder protein and amino acids and see prospects in the development of their production. The most common subjects for study in this regard are crickets, locusts, silkworm larvae, flies, worms, etc. Their protein value, amino acid, fatty acid and mineral composition, the content of vitamins, and other biologically active substances are studied.  \u0000The development of this direction is considered one of the ways to solve a number of urgent environmental and fodder problems on a biological basis.  \u0000Рurpose of the research was to study the protein value and complete amino acid composition of flour from insects, namely flour from the larvae of the BSF fly, crickets and snails, and the methods of its determining: crude protein by the Kjeldahl method, digestible protein with the help of 0,2% pepsin, and the digestibility coefficient, and the principles of conducting researches, as well as the characteristics of methods for determining the content of replaceable and essential amino acids, including sulfur-containing, using the Kapel-105M capillary electrophoresis system.  \u0000As a result of the research, it was found that cricket flour is the least valuable in terms of protein value (digestible protein and digestibility coefficient), and it is also poor in the content of nonessential and essential amino acids, compared to other studied types of insect flour. \u0000The best indicators of protein value were noted in the flour from BSF fly larvae in terms of the content of crude and digestible proteins, as well as the digestibility coefficient, which is 75.6%, which indicates its good digestibility by the bodies of animals and birds.  \u0000The highest content of amino acids is contained in the flour from BSF fly larvae. Taking into account the above results of crude protein content, digestibility, and digestibility in this sample, amino acid digestibility will also be higher compared to other flour samples. In addition, flour from BSF fly larvae is rich in sulfur-containing amino acids. The content of tryptophan and histidine, compared to other types of raw materials, is the highest.  \u0000The studied samples of insect flour contain a complete set of essential and nonessential amino acids, but BSF fly larvae flour and snail flour are more valuable for essential amino acids.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"43 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140969954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFICIENCY OF THE DRUG SUPERPYRIN IN THE COMPLEX APPLICATION IN THE TREATMENT OF BROILER CHICKENS","authors":"I. Kotsyumbas, O. Pyatnychko, T. Stetsko, M. Zhyla, N. Shkodyak, N. Lisova","doi":"10.36359/scivp.2024-25-1.09","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.09","url":null,"abstract":"The article presents the results of the study of the efficiency and safety of the drug Superpyrin, a powder for oral use, as a means of symptomatic therapy in the treatment of acute respiratory infections in broiler chickens. The active substances of the drug are acetylsalicylic, ascorbic and citric acids. The experiment was conducted on broiler chickens with clinical signs of bacterial disease – pasteurellosis. The diagnosis was made on the basis of clinical signs of the disease, the results of pathological and anatomical autopsy of dead chickens and the results of bacteriological examination of pat-material. Experimental and control groups of broiler chickens received the antimicrobial drug Doxycycline hyclate at a dose of 20 mg per kg of body weight per day orally with drinking water for 5 consecutive days. In addition to antimicrobial therapy, chickens-broiler of the experimental group received the test drug Superpyrin orally with drinking water at a dose of 1 g per 1 liter of water for 3 days. From the beginning of the treatment to the 14th day, the clinical state of the poultry of both groups was monitored, namely, the presence of adverse reactions, negative phenomena and body weight gain. Before the treatment and on the 10th day after the last administration of the drug Superpyrin, morphological and biochemical parameters of the chickens’ blood were examined. Hematological studies were conducted according to generally accepted methods, and biochemical – with the help of a semi-automatic biochemical analyzer Humalyzer 3000, using test-kits from the company Human. The obtained results were processed statistically. \u0000The results of a clinical study showed that the drug Superpyrin, a powder for oral use, in the recommended dosage, is an effective means for symptomatic therapy in the treatment of acute respiratory poultry disease of bacterial etiology. In the experimental group of chickens, the poultry mortality decreased, the treatment efficiency increased and body weight gains increased. No adverse reactions were recorded in poultry of the experimental group during the administration of the Superpyrin.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"2 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140967283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DEVELOPMENT AND VALIDATION OF HPLC-METHOD FOR QUANTITATIVE DETERMINATION OF PROPOXUR IN COLLARS AND SPRAYS","authors":"R. D. Ostapiv, V. І. Tkachenko, S. L. Humeniuk, L. K. Samarska, M. I. Bereziuk, H. D. Harvas","doi":"10.36359/scivp.2024-25-1.14","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.14","url":null,"abstract":"Propoxur is a carbamate non-systemic insecticide, an acetylcholinesterase blocker of invertebrates, leading to their paralysis and death. Propoxur is used in insect acaricidal sprays and collars to kill fleas and ticks on pets. \u0000The aim of the work was to develop a method of identification and quantification of propoxur in spray for external use and collars with different matrices. The method was developed and validated by indicators of selectivity, linearity, suitability parameters of the chromatographic system and repeatability. Spray and collars with different polymer composition were used as a sample-object for the development of the technique. The standard sample and the test sample of the spray were dissolved in acetonitrile to a propoxur concentration of 50 μg/ml. The collar was dissolved in tetrahydrofuran and acetonitrile was added to precipitate the matrix. The samples were separated on a Dionex Ultimate 3000 chromatograph equipped with chromatographic column Acclaim C18 150×4.6, 5 μm. The mobile phase was a mixture of acetonitrile and water in a volume ratio of 80:20. Propoxur was detected at an absorption wavelength of 270 nm. \u0000Under the above conditions, it was possible to completely separate propoxur (retention time of the chromatographic peak – 2.2 min) and other components of the studied drugs. At the same time, the suitability parameters of the chromatographic system did not exceed the limits specified in the recommendations of the USA Food and Drug Association. For propoxur, the efficiency of the chromatographic system was 10,300–10,540 theoretical plates. The relative standard deviation (RSD) for the peak areas of the active substance was ± 0.37%, and the peak separation ratio (RS) of propoxur and other components of the drug was 3.1–5.7. The symmetry coefficient of the propoxur peak was 1.49. The calibration curve was linear in the recommended DFU 2.0 range (80–120% of the nominal concentration of the active substance). The coefficient of linearity (R2) for propoxur was 0.9985.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"28 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140968659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHARACTERISTICS OF INSECTOFAUNA OF CATTLE FARMS","authors":"L. V. Nahorna, I. V. Proskurina, R. V. Dolbanosova, A. M. Tomik","doi":"10.36359/scivp.2024-25-1.13","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.13","url":null,"abstract":"The article presents data on the determination of the entomofauna of zoophilous flies in the conditions of the cattle breeding farm. Were subjected to parasitological research cattle of various ages: dairy cows, heifers of mating age, calves. The research was carried out on pastures, in production premises and walking areas. As a result of the conducted research, it was established that the main representatives of zoophilic flies parasitizing animals in pasture conditions were: Lyperosia irritans, Haematobia stimulans, Musca autumnalis Musca vitripennis. The following types of flies in the case of animals staying in the production premises, were identified on them: Musca domestic, Fannia canicularus, Calliphora uralensis, Calliphora visina, Lucilia sericata and Muscina stabulans. It was established that the extent of infestation by zoophilous flies was 100% among all age groups of cattle. Intensity of infestation in the group of dairy cows was 270.22±4.28 specimens/animal, among heifers and heifers of mating age – 244.67±3.49 specimens/animal, and among calves – 81.67±1.14 specimens/animal. We identified a clear trend regarding the specifics of parasitic insect damage in cattle of different breeds. When staying within the same production group, the highest intensity of infestation (354.50±5.08 insects per animal) was found in black Holstein cows, and the lowest II indicator was found in Simmental cows - 159.83±1.41 insects per animal. The intensity of the infestation of cows by zoophilic flies among representatives of the Holstein breed is 28% higher than that of the Simmental breed, and also 25% higher than that of the cows of the Ukrainian black-spotted dairy breed. It was noted that with high indicators of the intensity of invasion by zoophilous flies, the animals showed the maximum degree of restlessness, when analyzing behavioral reactions and the level of well-being of cows. It manifested itself in a constant effort to be in motion. Therefore, as a result of the conducted complex of studies, the extreme relevance of insecticidal treatments of cattle of different age groups has been proven, since a wide range of zoophilic flies has been identified in the places where animals stay.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"44 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140971404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PHARMACOCHEMICAL AND TECHNOLOGICAL QUALITY INDICATORS OF THE VETERINARY MEDICINAL PRODUCT BASED ON BIRCH TAR","authors":"М. В. Кychan, R. О. Vasiv, R. M. Sachuk, L. Kalynovska","doi":"10.36359/scivp.2024-25-1.07","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.07","url":null,"abstract":"To characterize and determine the quality of the veterinary medicinal drug «Kubazol» (solution for external use, aerosol), which includes birch tar as an active substance and auxiliary substances: ethyl acetate, polybutyl methacrylate, it is important to control the quality of the incoming raw materials and properly manufacture the medicinal product. \u0000The purpose of research is the development of a leaflet-tab of a veterinary drug, methods of quality control of the active substance and auxiliary substances of a solution for external use based on birch tar, and the technology of drug production. \u0000The veterinary drug «Kubazol» is a viscous liquid from yellow to brown in color with a specific smell of its components. 1 ml of the drug contains: birch tar – 40 mg, auxiliary substances: ethyl acetate, polybutyl methacrylate – up to 1 ml. \u0000«Kubazol» is prescribed for the treatment and prevention of lesions of the skin (wounds, dermatitis, eczema), claws (injuries, superficial panaritium), hooves (rot of the hooves, etc.) in dogs, wild pigs, wild birds, sport horses and pigs (boars after castration). \u0000The work presents the characteristics of the raw materials of the veterinary medicinal drug «Kubazol» (solution for external use, aerosol), describes the technological features of the manufacture and standardization of the drug based on birch tar, and offers a specification for the active substance and auxiliary substances. The technological scheme for the production of the drug included: preparation of aluminum cylinders, filling with the finished solution, removal of air from the cylinders, fastening of the valve, introduction of the propellant, testing for strength and tightness, drying of the cylinders, pressure testing, installation of the atomizer and checking of the quality of spraying and marking. \u0000On the basis of the proposed specification and approaches to laboratory quality control of the solution for external application of an aerosol based on birch tar, production documentation was developed that corresponds to the materials of the registration dossier for the veterinary drug «Kubazol». Test results are properly investigated and documented in accordance with the Standard Operating Procedure (SOP).","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"6 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140968915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DETERMINATION OF THE SENSITIVITY OF DERMATOMYCOSIS CAUSES TO FUNGICIDES","authors":"U. Z. Berbeka, V. I. Kushnir, I. S. Semen, I. Kushnir, D. F. Hufriy, H. V. Kolodiy, S. Murska","doi":"10.36359/scivp.2024-25-1.02","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.02","url":null,"abstract":"A microbiological study of the affected areas of the skin of dogs and cats was carried out for the detection of microscopic fungi. The following microscopic fungi were isolated from the pathological material: Candida spp., Aspergillus brasiliensis, Epidermophyton spp., Microsporum spp., Mucor spp., Trichophyton spp., Mallasseria spp., Sporotrich spp. \u0000Isolated microscopic fungi of the genus Malassezia spp. belong to the superficial mycoses (keratomycoses) and affect the surface layers of the skin and fur. Epidermatophytes: Trichophyton spp., Epidermophyton spp., Microsporum spp. affect the epidermis, skin, and coat. In addition, opportunistic fungi of the genus Aspergillus brasiliensis were found in the studied samples. \u0000It was established that the sensitivity of fungi isolated from the affected areas of the skin of dogs and cats to a 1% solution of ketonazole and clotrimazole is different. In particular, a 1% solution of ketonazole showed significantly higher activity compared to a 1% solution of clotrimazole. Thus, when determining the fungicidal effect of ketonazole, the growth retardation zone of the dermatophyte Trichophyton spp. was 34.3±0.6 mm, and the 1% clotrimazole solution was 21.3±0.3 mm. \u0000Ketonazol also showed higher fungicidal activity against the microscopic fungi Aspergillus brasiliensis and Candida spp., compared to clotrimazole. Thus, the activity of ketonazole was, respectively, 55.7 and 48.4% higher compared to clotrimazole. \u0000Clotrimazole showed the lowest fungicidal effect on Aspergillus brasiliensis, Mallasseria spp., Mucor spp., and Epidermophyton spp., the growth retardation zones of microscopic fungi were, respectively, 14.3±0.3, 14.3±0.6, 14.6± 0.6 and 16.6±0.3 mm.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"58 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140970263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PREVENTION OF INTESTINAL INFECTIONS OF BACTERIAL ETIOLOGY IN PIGS","authors":"Tomash Verteletski, V. Stybel, I. Mazur, A. Kolpak","doi":"10.36359/scivp.2024-25-1.04","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.04","url":null,"abstract":"Intestinal infections of bacterial etiology are among the most common diseases in pigs of different age groups. Healthy gastrointestinal tract is the basis for successful pig farming. Therefore, the prevention and control of major gastrointestinal infections is a key to farm profitability. \u0000Intestinal infections are caused by both pathogenic and opportunistic pathogenic bacteria. The most common diseases caused by pathogenic microorganisms include dysentery, ileitis and salmonellosis. Their causative agents are the bacteria Brachyspira spp., Lawsonia spp. and Salmonella spp. respectively. The most common opportunistic pathogenic bacteria are: Escherichia coli, Clostridium spp. and Proteus spp. \u0000Bacterial intestinal infections are diverse and widespread, and therefore cause significant economic losses for livestock farms. They suffer significant losses due to animal mortality, reduced productivity and, as a result, increased treatment costs. Therefore, the efforts of scientists should be aimed at creating innovative approaches and effective therapeutic agents that would not only treat but also prevent bacterial intestinal infections. \u0000The article presents data on traditional and innovative approaches to the prevention of bacterial intestinal infections in pigs. \u0000The advantages of using feed additives for the prevention and treatment of bacterial intestinal infections in pigs are described.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"43 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140970763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SUPPLY FORMATION IN THE NATIONAL COMPOUND FEED MARKET AND MILITARY OPERATIONS AFFECT THE PERFORMANCE OF THE FEED INDUSTRY","authors":"S. M. Temnenko, V. V. Shyyan, D. F. Marchenkov","doi":"10.36359/scivp.2024-25-1.26","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.26","url":null,"abstract":"The article describes the factors that influence for formation the offer on the compound feed market in Ukraine. In particular, in the period before the full-scale invasion in 2022, the main players in the market were compound feed plant integrated into agricultural holdings. \u0000At the same time, about a third of the market belonged to the MHP Holding, and the main industries consuming compound feed were poultry and pig farming. In peacetime, the formation of the price of compound feed was influenced by two main factors: the price of feed raw materials and the cost of feed additives. Thus, in 2020-2021, the market faced a significant increase in the price of compound feed, which was caused by the reduction in grain and sunflower production. \u0000With the beginning of the full-scale invasion of the russian federation on the territory of Ukraine and war, the agricultural sector suffered huge losses. Due to the loss of territories, mining of farmlands, destruction of agricultural machinery, destruction of granaries, blocking of seaports and disruption of logistics chains, the fodder industry of Ukraine require large capital investments for its recovery. At the same time, a thoughtful use of the funds allocated for the reconstruction of Ukraine by the partner states after the victory will help reform the industry. In particular, stimulating the development of small and medium-sized enterprises will help reduce the influence of big business on the supply side of the national market of compound feed.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"26 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140971741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COLD INHIBITION OF BIOACTIVITY OF PROBIOTIC MYCOBACTERIA AND AEROCOCCI IN THE MICROBIOME","authors":"V. V. Zazharskyi, A. O. Sosnytska, A. P. Paliy, I. A. Biben","doi":"10.36359/scivp.2024-25-1.06","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.06","url":null,"abstract":"The organism of farm animals is constantly under the influence of various factors of the external environment, and one of the negative factors of violation of the technology of keeping and creation of unsatisfactory conditions of existence with deterioration of well-being is cold injury. Mostly it manifests itself as a permanent effect of positive temperatures well below the physiological norm or periodic fluctuations of an uncomfortable temperature. Such a stress factor of low intensity, but permanent over a long period of time, causes negative pathophysiological changes in the macroorganism with the development of immune-depression, metabolic syndrome, perversions of the qualitative composition of the microbiome and, as a result, disruption of native physiological processes of stimulation of cellular mechanisms of nonspecific innate immunity, induced by immune-biological mechanisms of the functioning of neutrophil granulocytes. The negative effect of low-intensity permanent cold stress was studied on a model object - murchakаs, which were kept for two weeks at a temperature of 4-6 °C under conditions of light and movement restriction. Before the start of the experiment, initial microbiological studies of the microbiome of the large intestine were conducted using generally accepted methods. Resident indigenous probiotic prokaryotes - M. vaccae & A. viridans, which possessed typical species characteristics, were isolated. Pathogenic variants of enterobacteria were not isolated, isolated cultures of E. coli were apathogenic and belonged to the usual normal flora. A two-week cold injury resulted in the disappearance of the indigenous probiotic microbiota M. vaccae & A. viridans, which are indicator prokaryotes of the physiological well-being of the macroorganism, from the microbiome. At the same time, the number of potentially pathogenic enteral microorganisms, coccal and rod-shaped, increased. This was correlated with a decrease in the phagocytic activity of native neutrophil granulocytes and their preformed filamentous spatial nucleoprotective mesh structures, which inhibit the de-fragmentary function in relation to genetically non-syngenic objects.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"53 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140970889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INFLUENCE OF FEED ADDITIVE \"ENZAKTIVE MIX\" ON THE HEMATOLOGICAL PROFILE OF THE BLOOD OF SOWS AND THEIR PIGLETS","authors":"T. Prudyus, N. Broda","doi":"10.36359/scivp.2024-25-1.17","DOIUrl":"https://doi.org/10.36359/scivp.2024-25-1.17","url":null,"abstract":"The dynamics of the haematological profile changes and the productivity of sows and piglets obtained from them when feeding the feed additive \"EnzActive Mix\" were described in the article. The feed additive contains yeast of the genus Saccharomyces cerevisiae with an activity of at least 1.5 x 10^10 CFU/g and a six enzymes complex with protease, cellulase, xylanase, ɑ-amylase, β-gluconase, phytase, which are located under the layer of yeast cells. \u0000The results of the study showed that the use of \"EnzActive Mix\" in sows and their piglets’ diet has a stimulating effect on the oxygen transport function of blood. This is evidenced by a higher number of erythrocytes and platelets, a higher concentration of haemoglobin and haematocrit in the blood of sows of the experimental group compared to the control group on 21st day of lactation (p<0.05). Addition of the feed additive \"EnzActive Mix\" to the diet caused changes in certain forms of leukocytes ratio in the sows’ blood. Thus, during this period, a higher (p<0.05) relative lymphocytes number and a tendency to decrease of segmented neutrophils number in the blood of experimental group sows compared to the control group were found. \u0000  Similar changes were noted in the haematological parameters study of piglets obtained from these sows. In particular, the leukocytes number in the blood of the experimental group piglets at 5-, 14- and 28-day age was higher than in their peers of the control group. At the same time, on the 5th day of life, the differences relatively to the control group animals were significant (p<0.05). Feeding of the feed additive led to a decrease in the segmented neutrophils relative number in the blood of the experimental group piglets on the 14th and 28th day of life (p<0.05) and an increase in the lymphocytes number (p<0.05) during the indicated periods of the study. \u0000The positive effect of the feed additive \"EnzActive Mix\" on the productivity parameters of the studied animals was established. In particular, the body weight of experimental group piglets at 5-, 14- and 28-day age was 7.8%, 13.7% (p<0.05) and 8.4% (p<0.01) higher, respectively, than that of the control group.","PeriodicalId":21617,"journal":{"name":"Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology","volume":"99 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140968239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}