Revista espanola de fisiologia最新文献_第6页

Effects of hypothermic perfusion on pulmonary circulation in isolated rabbit lung. 低温灌注对兔离体肺循环的影响。

Revista espanola de fisiologia Pub Date : 1996-03-01

R Martínez-Ruiz, A H Sillau, M A Rico-Orsini, S Tristano-Castiglioni, R Sánchez de León

{"title":"Effects of hypothermic perfusion on pulmonary circulation in isolated rabbit lung.","authors":"R Martínez-Ruiz, A H Sillau, M A Rico-Orsini, S Tristano-Castiglioni, R Sánchez de León","doi":"","DOIUrl":"","url":null,"abstract":"The effects of hypothermic perfusion have been studied by using different perfusates in 24 isolated rabbit lung preparations, divided into three groups: G1, perfused with blood (hematocrit of 10%) and G2 and G3, perfused with erythrocyte-free plasma plus 6% protein in saline. In both G1 and G2 groups left atrial pressures were kept below airway pressure (Zone II conditions), and in G3 it was higher than airway pressure (Zone III conditions). Perfusate flow, pulmonary artery pressure, pulmonary vascular resistance, left atrial pressure, fluid filtration rate, colloid osmotic pressure and temperature were not different (p > 0.1) between G1 and G2 at the beginning of the experiments. Lowering perfusate temperature from 38 degrees C to 28 degrees C produced a significant increase in pulmonary artery pressure and pulmonary vascular resistance in G1 but they decreased in G2 lungs (p < 0.05). Fluid filtration rate increased in both groups during hypothermia. These responses were not inhibited by an alpha-adrenergic receptor blocker or a pulmonary vasodilator. In G3 lungs no changes were observed. The differences in the hemodynamic effects of hypothermia observed in G1 and G2, both in Zone II conditions, could result from the differences in the vessel distention state obtained by each of the perfusate before initiating hypothermia. As perfusate viscosity increase with cold, a greater possibility of vessel distention in G2 lungs occurs. This explains the decrease in pulmonary artery pressure and pulmonary vascular resistance with cold in this group. The increase in fluid filtration rate observed with hypothermia in G1 and G2 may be due to increases in fluid exchange area.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"52 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19747046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipid and lipoprotein changes throughout the term-period in neonates from the Toledo Study. 托莱多研究中，脂质和脂蛋白在新生儿足月期间的变化。

Revista espanola de fisiologia Pub Date : 1996-03-01

S Bastida, C Cuesta, S Perea, A Aragonés, F J Sánchez-Muniz

引用次数: 0

Characterization and quantification of apolipoprotein E in the genetically hypercholesterolemic rat (RICO). 遗传性高胆固醇血症大鼠(RICO)载脂蛋白E的表征和定量。

Revista espanola de fisiologia Pub Date : 1996-03-01

L E Cardona-Sanclemente, F Sultan, S Griglio

引用次数: 0

Platelets isolated by albumin gradient retain normal activation pathways. 通过白蛋白梯度分离的血小板保持正常的活化途径。

Revista espanola de fisiologia Pub Date : 1996-03-01

A M Vecino, J L Navarro, J M Cesar

引用次数: 0

Effects of different subchronic treatments with lindane on some brush border enzymes in rat jejunum. 林丹不同亚慢性处理对大鼠空肠刷状缘酶的影响。

Revista espanola de fisiologia Pub Date : 1996-03-01

M J Moreno, S Pellicer, M P Fernández-Otero

{"title":"Effects of different subchronic treatments with lindane on some brush border enzymes in rat jejunum.","authors":"M J Moreno, S Pellicer, M P Fernández-Otero","doi":"","DOIUrl":"","url":null,"abstract":"Subchronic lindane (gamma-HCH) intoxication by oral or s.c. injection over 7 and 15 days, induced a significant inhibition in rat jejunum maltase activity when the pesticide was administered at doses of 20 mg/kg b. wt. However, maltase levels remained unaffected in those animals injected with 10 mg/kg of lindane. A longer period of s.c. lindane exposure (30 days) at doses of 10 mg/kg induced a significant decrease in maltase activity, although the injection of 20 mg/kg over the same period did not alter this enzyme activity. When this lindane dose was s.c. injected over 20 days a significant inhibition of maltase activity was observed. However no changes in this enzyme were found in rats injected over 25 days. This fact seems to suggest that between 20-25 days of pesticide exposure the organism develops possible regulatory mechanisms to counteract the alterations induced by this dose of lindane on maltase activity. Lactase and alkaline phosphatase activities were not altered by lindane action in different treatments performed. Sucrase activity was only altered in oral injected rats at doses of 20 mg/kg over 15 days. In conclusion, maltase activity seems to be more sensitive to lindane action than other brush border enzymatic proteins; lindane effects on this enzyme depend on the injected dose and the pesticide administration period duration.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"52 1","pages":"37-44"},"PeriodicalIF":0.0,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19747051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of somatostatin and somatotropin on the in vitro testicular steroidogenesis in hamster. 生长抑素和生长激素对仓鼠体外睾丸甾体生成的影响。

Revista espanola de fisiologia Pub Date : 1995-12-01

S S Oh, R Khardori, D K Kopplin, A G Amador

{"title":"Effects of somatostatin and somatotropin on the in vitro testicular steroidogenesis in hamster.","authors":"S S Oh, R Khardori, D K Kopplin, A G Amador","doi":"","DOIUrl":"","url":null,"abstract":"Adult hamsters were exposed to short-photoperiod, and injected with either somatotropin (GH), somatostatin (GHRIH), or saline for eight weeks. Hamster testis fragments of similar size were incubated with or without hCG. No significant differences in the basal media testosterone and estradiol levels were observed among groups. Treatment with GH potentiated the hCG-dependent increase in media testosterone. Contrary to what was expected, treatment with GHRIH did not only not reduce the hCG-related elevation in media testosterone, but even produced a numerical increase of it. Treatment with GHRIH potentiated the hCG-dependent increase in media estradiol, whereas treatment with GH produced only a numerical increase of the response. Furthermore, the combined exposure to GHRIH and hCG appeared to cause an increase in the efficiency of testicular aromatase. Since previous data indicated that the combined deficiency of lactotropic and somatotropic actions severely impairs testicular steroidogenesis, treatment with GHRIH should have caused further steroidogenic impairment in hamsters exposed to short-photoperiod. Since this does not appear to be the case, it could be postulated that GHRIH has a direct stimulatory or at least a protective effect on testicular steroidogenesis.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"51 4","pages":"187-92"},"PeriodicalIF":0.0,"publicationDate":"1995-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19872560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum hemolytic and bactericidal activity in breast and formula-fed infants. 母乳和配方奶喂养婴儿的血清溶血和杀菌活性。

Revista espanola de fisiologia Pub Date : 1995-12-01

C Barriga, I Pombero, J Duran, A Forner, J Cardesa, A B Rodriguez

引用次数: 0

Evaluation of the left ventricular performance through equilibrium radionuclide angiocardiography. 通过平衡放射性核素心血管造影评价左心室功能。

Revista espanola de fisiologia Pub Date : 1995-12-01

J H Boix, F Alvarez, M Tejeda, J Monferrer, E Enrique, O Aznar, E Kuret, F Peydro, D Olivares

引用次数: 0

Effects of L-carnitine on the hypoxic atria from fed and fasted rats. 左旋肉碱对喂养和禁食大鼠缺氧心房的影响。

Revista espanola de fisiologia Pub Date : 1995-12-01

A Varela, V Dalamon, S Sacks, M Carregal, E A Savino

{"title":"Effects of L-carnitine on the hypoxic atria from fed and fasted rats.","authors":"A Varela, V Dalamon, S Sacks, M Carregal, E A Savino","doi":"","DOIUrl":"","url":null,"abstract":"The aim of the investigation was to assess whether L-carnitine, an essential cofactor in the mitochondrial transfer of fatty acids, would ameliorate the hypoxic-induced disturbances in the isolated rat atria. During hypoxia, the atria released lactate into the bathing medium and underwent a rise in resting tension and a decline of the peak developed tension and pacemaker frequency. The atria from 24-h fasted rats, which oxidize faster their endogenous triacylglycerol stores>> exhibited greater functional disturbances during hypoxia and a smaller recovery after reoxygenation, with respect to the fed rats' atria. Furthermore, at the end of the hypoxic incubation the fasted rats atria displayed a reduction of the free CoA content together with a 3-fold increase in the content of long-chain fatty-acyl CoA, in comparison with those of fed rats. The addition of 5 mM L-carnitine 60 min before the onset of hypoxia did not exert any effect on the hypoxic atria. In contrast, 20 mM L-carnitine accelerated the decline of the pacemaker activity in the fasted rat atria and worsened the contracture development in both nutritional states. The fall of the peak tension and the posthypoxic recovery as well as the levels of free CoA and long-chain fatty-acyl CoA, and lactate output, were not affected by 20 mM L-carnitine treatment. These data suggest that L-carnitine is not beneficial for the hypoxic rat atria, even in the fasted state, wherein the atrial fatty acid catabolism is increased.","PeriodicalId":21473,"journal":{"name":"Revista espanola de fisiologia","volume":"51 4","pages":"201-6"},"PeriodicalIF":0.0,"publicationDate":"1995-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19872562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of training on diverse hematologic parameters in Andalusian horses. 训练对安达卢西亚马血液学参数的影响。

Revista espanola de fisiologia Pub Date : 1995-12-01

B M Escribano, F M Castejon, R Santisteban, E I Aguera, M D Rubio

引用次数: 0