Scandinavian Journal of Gastroenterology最新文献

{"title":"The impact of IBD on ability to work and study: a patient perspective.","authors":"Anssi Mustonen, Rasmus Rankala, Markku Voutilainen, Kalle Mattila","doi":"10.1080/00365521.2024.2440794","DOIUrl":"10.1080/00365521.2024.2440794","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to explore the multifaceted ways in which inflammatory bowel disease (IBD) negatively affects working life and studies.</p><p><strong>Material and methods: </strong>IBD patients were identified by diagnosis codes from the hospital records of a Finnish University Hospital. Patients were sent questionnaires <i>via</i> mail and text messages. Respondents, being 561 patients, formed the sample. Hospital records and data of medications were combined to questionnaire data.</p><p><strong>Results: </strong>Over a fifth of the patients reported having to change their job due to IBD, whereas a third of the sample had to modify their work due to IBD. On average, they had changed jobs once. Most common modifications were to do fewer hours or work during different hours, decreasing the physical burden of their work and moving their workplace closer to a toilet. Around a fifth of the sample' studies were negatively influenced by IBD. Interestingly, clinical parameters or sex did not affect the probability of job modifications, changes or negative effects on studies.</p><p><strong>Conclusions: </strong>IBD has a considerable negative impact on many patients' studies and working life that extends beyond commonly studied absenteeism and presenteeism.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"37-41"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suboptimal adherence to a gluten-free diet in adults with both type 1 diabetes and celiac disease using urinary gluten immunogenic peptide measurement.","authors":"Kristine Vaage Hatlen, Therese Margrethe Lysell Lensnes, Christine Henriksen, Tore Julsrud Berg, Ingrid Nermoen, Knut Erik Aslaksen Lundin","doi":"10.1080/00365521.2024.2442688","DOIUrl":"10.1080/00365521.2024.2442688","url":null,"abstract":"<p><strong>Objectives: </strong>Concurrent type 1 diabetes (T1D) and celiac disease (CeD) pose challenges in insulin dosage adjustments and gluten-free dietary adherence. Urine testing for gluten immunogenic peptides (GIP) is a new method to detect gluten exposure within the last 3-12 h. Our aims were to compare gluten-free dietary adherence between T1D + CeD and CeD individuals and evaluate urinary GIP testing in an outpatient setting.</p><p><strong>Materials and methods: </strong>This observational cross-sectional study included three adult groups: (1) T1D and CeD, (2) CeD only, and (3) T1D only. T1D participants were recruited from outpatient clinics, the CeD group via social media. One urine sample (12 pm-7 pm) was analyzed using a qualitative immunographic GIP test. CeD participants completed 'Celiac Dietary Adherence Test' (CDAT) and 'Celiac Symptom Index' (CSI) questionnaires. IgA anti-transglutaminase 2 (IgA-TG2) and IgG anti-deamidated gliadin (IgG-DGP) serology were also analyzed.</p><p><strong>Results: </strong>197 participants, mean (SD) age 43 (15) years, were included. Female percentages were: CeD: 90%, T1D + CeD: 64%, and T1D: 47%. Positive urinary GIP was found in 15% (14/96) of T1D + CeD and 0% (0/50) of CeD (<i>p</i> = 0.002). As expected, most T1D only participants had positive urinary GIP (86%, 44/51). CDAT and CSI scores did not differ between T1D + CeD and CeD groups. Positive IgA-TG2 and/or IgG-DGP levels were found in 12% of T1D + CeD and 6% of CeD participants (<i>p</i> = 0.38).</p><p><strong>Conclusions: </strong>A single GIP urine test revealed higher gluten exposure in T1D + CeD versus CeD only, questioning dietary adherence in this population. Urinary GIP tests can be useful for clinical follow-up.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"28-36"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bedside endoscopic ultrasound guided gallbladder drainage in the Intensive Care Unit in critically ill patients.","authors":"Raj Jessica Thomas, Arjun Chatterjee, Mohamed Abdallah, Rajat Garg, Amandeep Singh, Prabhleen Chahal","doi":"10.1080/00365521.2024.2434631","DOIUrl":"10.1080/00365521.2024.2434631","url":null,"abstract":"<p><p>Cholecystectomy is the preferred treatment for acute cholecystitis in average surgical-risk patients. For those with high perioperative risk, percutaneous transhepatic gallbladder drainage (PT-GBD) and endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) are alternatives. However, PT-GBD is limited by contraindications such as large hepatic masses, significant ascites, and coagulopathy, and some critically ill patients cannot be transferred for PT-GBD or EUS-GBD. This case series demonstrates that bedside EUS-GBD in the ICU is technically feasible and safe for critically ill patients who are unsuitable for other interventions. Three cases involving severely ill patients successfully underwent bedside EUS-GBD with initial post-procedure improvement. Unfortunately, all patients eventually required comfort care due to their severe underlying conditions. These cases highlight EUS-GBD as an effective bedside option for gallbladder drainage in ICU patients when supported by multidisciplinary teams. Further research could confirm its expanded role in managing high-risk patients in intensive care.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"99-103"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A clinical pilot trial of an artificial intelligence-driven smart phone application of bowel preparation for colonoscopy: a randomized clinical trial.","authors":"Huang Zhong, Cong Hou, Zhong Huang, Xinlian Chen, Yan Zou, Han Zhang, Tingyu Wang, Lan Wang, Xiangbing Huang, Yongfeng Xiang, Ming Zhong, Mingying Hu, Dongmei Xiong, Li Wang, Yuanyuan Zhang, Yan Luo, Yuting Guan, Mengyi Xia, Xiao Liu, Jinlin Yang, Tao Gan, Wei Wei, Honghan Chen, Hang Gong","doi":"10.1080/00365521.2024.2443520","DOIUrl":"10.1080/00365521.2024.2443520","url":null,"abstract":"<p><strong>Background: </strong>High-quality bowel preparation is paramount for a successful colonoscopy. This study aimed to explore the effect of artificial intelligence-driven smartphone software on the quality of bowel preparation.</p><p><strong>Methods: </strong>Firstly, we utilized 3305 valid liquid dung images collected <i>via</i> mobile phones as training data. the most effective model was employed on mobile phones to evaluate the quality of bowel preparation. Secondly, From May 2023 to September 2023, colonoscopy patients were randomly assigned to two groups - the AI group (<i>n</i> = 116) and the control group (<i>n</i> = 116) - using a randomized, controlled, endoscopist-blinded method. We compared the two groups in terms of Boston Bowel Preparation Scale (BBPS) scores, polyp detection rate, adverse reaction rate, and factors related to bowel preparation quality. The primary endpoint was the percentage of patients who achieved a BBPS ≥6 among those who effectively utilized the smartphone software.</p><p><strong>Results: </strong>EfficientNetV2 exhibited the highest performance, with an accuracy of 87%, a sensitivity of 83%, and an AUC of 0.86. In the patient validation experiment, the AI group had higher BBPS scores than the control group (6.78 ± 1.41 vs. 5.35 ± 2.01, <i>p</i> = 0.001) and showed an improvement in the detection rate (71.55% vs. 56.90%, <i>p</i> = 0.020) for polyps. Multifactor logistic analysis indicated that compliance with enema solution usage rules (OR: 5.850, 95% confidence interval: 2.022-16.923), total water intake (OR: 1.001, 95% confidence interval: 1.001-1.002), and AI software reminders (OR: 2.316, 95% confidence interval: 1.096-4.893) were independently associated with BBPS scores ≥6.</p><p><strong>Conclusion: </strong>Compared with traditional methods, the use of artificial intelligence combined with software to send reminders can lead to more accurate assessments of bowel preparation quality and an improved detection rate for polyps, thus demonstrating promising clinical value.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"116-121"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eradication of Helicobacter pylori by a potassium-competitive acid blocker alone?","authors":"Helge Waldum, Reidar Fossmark","doi":"10.1080/00365521.2024.2444477","DOIUrl":"10.1080/00365521.2024.2444477","url":null,"abstract":"<p><strong>Aims: </strong><i>Helicobacter pylori (H. pylori)</i>, the dominating cause of gastric cancer, most often infects children initiating inflammation in the antral part and spreads orally to the oxyntic mucosa. Traditionally, eradication of <i>H. pylori</i> has been based upon a combination of antibiotics together with a proton pump inhibitor (PPI) to reduce gastric destruction of the antibiotics. Recently it has been shown that the more efficient inhibitors of acid secretion, the potassium-competitive acid blockers (PCABs) in combination with amoxicillin alone gave highly sufficient <i>H. pylori</i> eradication.</p><p><strong>Methods: </strong>To further elucidate the importance of gastric acidity we studied the literature for the connection between gastric acidity and the presence of <i>H. pylori</i>.</p><p><strong>Results: </strong>It is well-known that <i>H. pylori</i> is dependent of some acidity in the surroundings to neutralize NH₃ produced by its urease, explaining the loss of <i>H. pylori</i> in total oxyntic atrophy. With adequate dosing PCABs can induce almost complete anacidity for 24-h which probably is necessary for <i>H. pylori</i> eradication. Even a short period with hypergastrinemia may induce mutations in the target cell of gastrin, the enterochromaffin-like (ECL) cell which may contribute to the relatively short interval between <i>H. pylori</i> eradication and gastric cancer in the users of profound acid inhibitors.</p><p><strong>Conclusion: </strong>The use of PCABs alone dosed sufficiently seems promising for <i>H. pylori</i> eradication, but a combination with a gastrin antagonist would be preferable.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"10-12"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142897094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative factors predicting outcomes in patients with Perihilar cholangiocarcinoma undergoing curative resection-a 10-year single-center experience.","authors":"Hasan Ahmad Al-Saffar, Nicolai Schultz, Peter Nørrgaard Larsen, Eva Fallentin, Gro Linno Willemoe, Diana Elena Renteria Ramirez, Lucas Alexander Knøfler, Hans-Christian Pommergaard","doi":"10.1080/00365521.2024.2443515","DOIUrl":"10.1080/00365521.2024.2443515","url":null,"abstract":"<p><strong>Background: </strong>Perihilar cholangiocarcinoma (pCCA) has a 5-year overall survival (OS) ranging from 10-40%, following resection. However, prognostic models for postoperative outcomes are limited by long study timespan and variations in work-up. We investigated postoperative outcomes in patients resected for pCCA in a high-volume center with standardized work-up.</p><p><strong>Method: </strong>Patients resected with confirmed pCCA, between 2013 and 2023, were included. Cox-regression investigated association between postoperative factors and OS as well as disease-free survival (DFS).</p><p><strong>Results: </strong>Totally, 65 patients were resected for pCCA. The 1-, 3- and 5-year OS rates were 86.1%, 56.5% and 32.6% respectively. The 1-, 3- and 5-year DFS rates were 67.7%, 40.0% and 26.8%, respectively. Portal vein embolization (PVE) (HR 4.52 [CI 1.66-12.27], <i>p</i> = 0.003), lymph node metastasis (LNM) (HR 6.37 [CI 2.06-19.67], <i>p</i> = 0.001) and Clavien-Dindo (CD) ≥3a (HR 2.83 [CI 1.43-5.56], <i>p</i> = 0.002) were associated with inferior OS. Clavien-Dindo (CD) ≥3a (HR 2.10 [CI 1.05-4.22], <i>p</i> = 0.03) and T-stage >2 (HR 2.36 [CI 1.01, 5.05], <i>p</i> = 0.04) were associated with inferior and superior DFS, respectively.</p><p><strong>Conclusion: </strong>PVE, T-stage >2, LNM and CD ≥ III were associated with worse prognosis in resected pCCA. Research is needed to improve pre-operative detection of oncological features and patients with risk of major surgical complications.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"73-80"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DDR1 in pancreatic adenocarcinoma: unraveling the mechanisms of immune exclusion.","authors":"Long Cheng, Lina Wei, Qian Chen, Peirong Li, Dekui Zhang","doi":"10.1080/00365521.2024.2443505","DOIUrl":"10.1080/00365521.2024.2443505","url":null,"abstract":"<p><strong>Background: </strong>Pancreatic adenocarcinoma (PAAD) is a deadly cancer marked by extensive collagen deposition and limited response to immunotherapy. Discoidin domain receptor1 (DDR1), part of the transmembrane receptor tyrosine kinase family, is linked to inflammation regulation and immune cell infiltration. However, its role in controlling cytokines and chemokines in the microenvironment of PAAD is still unclear.</p><p><strong>Methods: </strong>Initially, RNA sequencing data from TCGA were utilized to investigate the expression of DDR1. Subsequently, the relationship between DDR1 and immune infiltration was examined through Gene Ontology (GO) and Gene Set Enrichment Analysis (GSEA) analysis, in conjunction with ssGSEA Immunoanalysis. Lastly, the effect of DDR1 on the malignant characteristics of PAAD cells was examined through <i>in vitro</i> experimentation, employing various techniques such as the CCK8 assay, colony formation assay and reverse transcription-quantitative polymerase chain reaction (RT-qPCR).</p><p><strong>Results: </strong>The research revealed a notable increase in the expression level of DDR1 in PAAD. Subsequent analysis indicated a correlation between the differential expression of DDR1 with chemokines and immune infiltration. Additionally, cellular experiments demonstrated that the downregulation of DDR1 led to enhanced expression of chemokines CCL4, CCL5 and CXCL10.</p><p><strong>Conclusion: </strong>DDR1 is linked to tumor immune infiltration, and the knockout of DDR1 results in the upregulation of chemokines CCL4, CCL5 and CXCL10 in Pan02 PAAD cells.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"81-90"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of functional defecation disorder in patients with constipation based on colonic transit test: a retrospective study.","authors":"Xiaoyang Ren, Xiaoni Yan, Jiao Zhu, Shuixiang He, Yan Yin","doi":"10.1080/00365521.2024.2434637","DOIUrl":"10.1080/00365521.2024.2434637","url":null,"abstract":"<p><strong>Background: </strong>This study aims to evaluate the diagnostic efficacy of colonic transit test (CTT) in cases of constipation associated with functional defecation disorders (FDD) within the Chinese population.</p><p><strong>Methods: </strong>A retrospective analysis was conducted involving 202 patients diagnosed with functional constipation, who underwent CTT, high-resolution anorectal manometry, and balloon expulsion test. Participants were categorized based on the Rome IV criteria, comprising 103 patients with FDD and 99 without. The study examined the symptomatic characteristics of both groups and assessed the diagnostic utility of CTT in identifying constipation with FDD.</p><p><strong>Results: </strong>The predominant symptom reported among individuals with chronic functional constipation was excessive straining, observed in 69.3% of cases. The incidence of hard stool passage and feelings of incomplete evacuation were significantly greater in the FDD group compared to the non-FDD group (47.6% vs. 31.3%, <i>p</i> = 0.018 and 50.5% vs. 25.3%, <i>p</i> = 0.001, respectively). The presence of three or more rectosigmoid (RS) residual markers and a transit index of 40% or greater demonstrated moderate diagnostic value for FDD, characterized by low sensitivity(44.7% and 47.6%) but high specificity(76.8% and 75.8%). The RS residual markers were effective in differentiating between FDD and normal transit constipation, but not effectively distinguish between FDD and slow transit constipation.</p><p><strong>Conclusions: </strong>The presence of RS residue serves primarily as an exclusionary criterion for diagnosing FDD. In cases of slow transit constipation, but not normal transit constipation, it is imperative to conduct multiple kinetic assessments to accurately differentiate between FDD and other types of constipation.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"13-19"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the pocket-creation method with the conventional method of endoscopic submucosal dissection for cecal and ascending colon lesion resection.","authors":"Dong Yang, Ke Tao, Qingying He, Nan Zhang, Hong Xu","doi":"10.1080/00365521.2024.2440788","DOIUrl":"10.1080/00365521.2024.2440788","url":null,"abstract":"<p><strong>Objective: </strong>To compare the pocket-creation method (PCM) with the conventional method of endoscopic submucosal dissection (ESD) for cecal and ascending colon lesion resection.</p><p><strong>Methods: </strong>The data of patients who underwent ESD for cecal or ascending colon lesions were retrospectively analyzed. The patients were divided into the PCM group and the conventional group according to the method of ESD. Baseline data, endoscopic characteristics, dissection speed, pathological results and adverse events were compared between the two groups. Dissection speed was also analyzed.</p><p><strong>Results: </strong>Overall, 122 patients were included. The dissection speed in the PCM group was higher than in the conventional group (0.20 [0.11, 0.32] cm²/min vs. 0.12 [0.08, 0.20] cm²/min, Z = -2.813, <i>p</i> = 0.005). The proportion of patients with injury to the muscularis propria layer in the PCM group was lower than in the conventional group, though the difference was not significant (19.4% vs. 29.1%, χ² = 1.215, <i>p</i> = 0.270). The univariate analysis showed that low body mass index (BMI), use of the PCM, long lesion diameter, large lesion area, and minimal fibrosis were independent risk factors for fast dissection (all <i>p</i> < 0.05). The logistic regression analysis showed that high dissection speed was associated with the choice to use the PCM, longer lesion diameter, and no fibrosis.</p><p><strong>Conclusion: </strong>For cecal and ascending colon lesions, the PCM is a better choice than the conventional method, especially in patients with fibrosis, and large lesion area.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"110-115"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ERCP catheter or dilator? Which is best for fistula dilation following guidewire placement in EUS-guided transhepatic biliary drainage?","authors":"Mitsuru Sugimoto, Tadayuki Takagi, Rei Suzuki, Hiroyuki Asama, Hiroshi Shimizu, Kentaro Sato, Rei Ohira, Jun Nakamura, Mika Takasumi, Minami Hashimoto, Tsunetaka Kato, Takumi Yanagita, Takuto Hikichi, Hiromasa Ohira","doi":"10.1080/00365521.2024.2440449","DOIUrl":"10.1080/00365521.2024.2440449","url":null,"abstract":"<p><strong>Objectives: </strong>EUS-guided biliary drainage (EUS-BD) is performed after endoscopic transpapillary biliary drainage fails. Although fistula dilation is one of the most difficult steps of EUS-BD, whether an ultratapered ERCP catheter or a dilator is the best choice for fistula dilation is unclear. In this study, we aimed to identify the optimal device for fistula dilation after guidewire placement.</p><p><strong>Materials and methods: </strong>Patients who underwent EUS-guided transhepatic biliary drainage between March 2019 and July 2024 were enrolled in this study. The successful fistula dilation rates, patient characteristics, and EUS-BD procedures were compared between patients who underwent fistula dilation with an ultratapered ERCP catheter (Catheter group) and patients who underwent fistula dilation with new dilators (ES dilator or Tornus ES) (Dilator group).</p><p><strong>Results: </strong>A total of 38 fistula dilation sessions were performed. Among these 38 sessions, 12 involved a catheter, and 26 involved a dilator. The ERCP catheter was specifically intended for use with 0.025 guidewires, and the dilators were specifically intended for use with 0.018 or 0.025 guidewires. Successful fistula dilation was more frequently achieved in the dilator group than in the catheter group (100% (26/26) vs. 50% (6/12), <i>p</i> < 0.01). When the cases were limited to those involving devices specifically intended for use with 0.025 guidewires, the results were similar (dilator group 100% (22/22) vs. catheter group 50% (6/12), <i>p</i> < 0.01). The other outcomes were not significantly different between the two groups.</p><p><strong>Conclusions: </strong>A dilator is more promising than a tapered ERCP catheter for fistula dilation in EUS-BD.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":" ","pages":"104-109"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}