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Scandinavian Journal of Gastroenterology最新文献

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Diarrhoea of unknown cause: medical treatment in a stepwise mannerManagement of Idiopathic Diarrhoea Based on Experience of Step-Up Medical Treatment. 原因不明的腹泻：循序渐进的医学治疗基于循序渐进医学治疗经验的特发性腹泻管理。
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-02-11 DOI: 10.1080/00365521.2024.2313061
Ann-Sofie Jansson-Rehnberg, Asbjørn Mohr Drewes, Jon Sponheim, Christer Borgfelt, Andreas Münch, Wilhelm Graf, Magnus Simrén, Greger Lindberg, Per M Hellström
{"title":"Diarrhoea of unknown cause: medical treatment in a stepwise manner<b>Management of Idiopathic Diarrhoea Based on Experience of Step-Up Medical Treatment</b>.","authors":"Ann-Sofie Jansson-Rehnberg, Asbjørn Mohr Drewes, Jon Sponheim, Christer Borgfelt, Andreas Münch, Wilhelm Graf, Magnus Simrén, Greger Lindberg, Per M Hellström","doi":"10.1080/00365521.2024.2313061","DOIUrl":"10.1080/00365521.2024.2313061","url":null,"abstract":"<p><p>The basic principle for the treatment of idiopathic diarrhoea (functional diarrhoea K59.1) is to delay transit through the gut in order to promote the absorption of electrolytes and water. Under mild conditions, bulking agents may suffice. With increasing severity, antidiarrhoeal pharmaceuticals may be added in a stepwise manner. In diarrhoea of unknown aetiology, peripherally-acting opioid receptor agonists, such as loperamide, are first-line treatment and forms the pharmaceutical basis of antidiarrheal treatment. As second-line treatment opium drops have an approved indication for severe diarrhoea when other treatment options fail. Beyond this, various treatment options are built on experience with more advanced treatments using clonidine, octreotide, as well as GLP-1 and GLP-2 analogs which require specialist knowledge the field.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139723956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrointestinal cancer precursor risk and mortality in pancreatic intraductal papillary mucinous neoplasms: a nationwide cohort study. 胰腺导管内乳头状黏液瘤的胃肠癌前兆风险和死亡率：一项全国性队列研究。
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-02-13 DOI: 10.1080/00365521.2024.2310162
Miroslav Vujasinovic, Peter Elbe, Isabella Ekheden, Qiao-Li Wang, Marcus Thuresson, Bjorn Roelstraete, Sam Ghazi, J-Matthias Löhr, Jonas F Ludvigsson
{"title":"Gastrointestinal cancer precursor risk and mortality in pancreatic intraductal papillary mucinous neoplasms: a nationwide cohort study.","authors":"Miroslav Vujasinovic, Peter Elbe, Isabella Ekheden, Qiao-Li Wang, Marcus Thuresson, Bjorn Roelstraete, Sam Ghazi, J-Matthias Löhr, Jonas F Ludvigsson","doi":"10.1080/00365521.2024.2310162","DOIUrl":"10.1080/00365521.2024.2310162","url":null,"abstract":"<p><strong>Background and aims: </strong>Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a precursor of pancreatic cancer. While earlier research has shown a high prevalence of synchronous/metachronous extrapancreatic tumors in IPMN patients, these studies have often been small with retrospective data collection. The aim of the study was to examine absolute and relative risks of non-pancreatic gastrointestinal (GI) cancer precursors and mortality in histologically confirmed IPMN.</p><p><strong>Methods: </strong>Through the nationwide ESPRESSO histopathology cohort, we retrieved data on IPMN between 1965 and 2016. Each index case was matched to ≤5 general population controls. Through Cox regression, we estimated hazard ratios (HRs) for future GI cancer precursors and death.</p><p><strong>Results: </strong>A total of 117 patients with IPMN and 539 age- and sex-matched controls were included. Over a median of 2.1 years of follow up, we confirmed two (1.7%) incident GI cancer precursors in IPMN vs. four (0.7%) in controls, corresponding to an HR of 1.89 (95%CI = 0.34-10.55). By contrast, IPMN patients were at increased risk of death (HR 3.61 (95%CI = 1.79-7.27)). The most common cause of death in IPMN was pancreatic cancer (<i>n</i> = 14; 45.2% of all deaths).</p><p><strong>Conclusions: </strong>We found no association between IPMN and other GI cancer precursors. This argues against comprehensive routine surveillance for other GI cancer precursors in IPMN patients. Mortality was increased in IPMN with pancreatic cancer being the most common cause of death, indicating the need for lifelong follow up in all resected and non-resected patients with IPMN. However, results should be confirmed in larger cohorts.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age and incidence of occult pancreaticobiliary reflux in patients with benign gallbladder diseases. 良性胆囊疾病患者的年龄与隐性胰胆管反流的发生率。
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-02-06 DOI: 10.1080/00365521.2024.2311358
Yukai Xiang, Chen Qiu, Hai Hu, Jingli Cai, Xuanbo Da, Xiangyu Kong, Yubin Wang, Chuanqi He, Cheng Zhang, Yulong Yang
{"title":"Age and incidence of occult pancreaticobiliary reflux in patients with benign gallbladder diseases.","authors":"Yukai Xiang, Chen Qiu, Hai Hu, Jingli Cai, Xuanbo Da, Xiangyu Kong, Yubin Wang, Chuanqi He, Cheng Zhang, Yulong Yang","doi":"10.1080/00365521.2024.2311358","DOIUrl":"10.1080/00365521.2024.2311358","url":null,"abstract":"<p><strong>Background: </strong>Occult pancreaticobiliary reflux (OPBR) has a significant correlation with diseases of the gallbladder and biliary system. This study examined the incidence of OPBR by age in patients with benign gallbladder diseases.</p><p><strong>Methods: </strong>We assessed 475 patients with benign gallbladder diseases who underwent surgery at Shanghai East Hospital from December 2020 to December 2021. Bile samples collected during surgery were tested for amylase. Patients with bile amylase >110 U/L (<i>n</i> = 64) were classified as the OPBR group; the rest (<i>n</i> = 411) as controls.</p><p><strong>Results: </strong>Of the participants, 375 had gallbladder stone (GS), 170 had gallbladder polyp (GP), and 49 had gallbladder adenomyomatosis (GA). The OPBR group was generally older, with OPBR incidence increasing with age, peaking post-45. Rates by age were: 4.9% (<35), 5.2% (35-44), 20.7% (45-54), 22.5% (55-64) and 17.6% (≥65), mainly in GS patients. ROC analysis for predicting OPBR by age yielded an area under the curve of 0.656, optimal cut-off at 45 years. Logistic regression indicated age > 45, GP, male gender, and BMI ≥ 24 kg*m<sup>-2</sup> as independent OPBR predictors in GS patients. Based on these variables, a predictive nomogram was constructed, and its effectiveness was validated using the ROC curve, calibration curve and decision curve analysis (DCA). Further stratification revealed that among GS patients ≤ 45, concurrent GA was an OPBR risk; for > 45, it was GP and male gender.</p><p><strong>Conclusions: </strong>The incidence of OPBR in GS patients is notably influenced by age, with those over 45, especially males without GP, being at heightened risk.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139692819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in the knowledge of the mechanism of reflux hypersensitivity. 反流过敏机制知识的最新进展。
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-05-01 Epub Date: 2024-02-11 DOI: 10.1080/00365521.2024.2310177
Li Na Ying, Yan Sun, Li Yang Cui, Zhen Yu Zhang, Rui Fang Li, Jun Zhang
{"title":"Recent advances in the knowledge of the mechanism of reflux hypersensitivity.","authors":"Li Na Ying, Yan Sun, Li Yang Cui, Zhen Yu Zhang, Rui Fang Li, Jun Zhang","doi":"10.1080/00365521.2024.2310177","DOIUrl":"10.1080/00365521.2024.2310177","url":null,"abstract":"<p><p>Reflux hypersensitivity (RH) is a subtype of gastroesophageal reflux disease. The Rome IV criteria separated RH from the original nonerosive reflux disease subgroup and classified it as a new functional oesophageal disease. Recently, the pathogenesis of RH has become the focus of research. According to the latest research reports, upregulation of acid-sensitive receptors, distribution of calcitonin gene-related peptide-positive nerve fibres, and psychiatric comorbidity have key roles in the pathogenesis of RH. This work reviews the latest findings regarding RH mechanisms.</p>","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139723957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and efficacy of thalidomide in treatment of gastrointestinal bleeding secondary to angioectasias: a systematic review and meta-analysis 沙利度胺治疗血管瘤继发性消化道出血的安全性和有效性：系统回顾和荟萃分析
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-04-17 DOI: 10.1080/00365521.2024.2342404
Sahib Singh, Babu P. Mohan, Omid Sanaei, Rakesh Vinayek, Sudhir Dutta, Dushyant Singh Dahiya, Ishfaq Bhat, Neil Sharma, Douglas G. Adler
{"title":"Safety and efficacy of thalidomide in treatment of gastrointestinal bleeding secondary to angioectasias: a systematic review and meta-analysis","authors":"Sahib Singh, Babu P. Mohan, Omid Sanaei, Rakesh Vinayek, Sudhir Dutta, Dushyant Singh Dahiya, Ishfaq Bhat, Neil Sharma, Douglas G. Adler","doi":"10.1080/00365521.2024.2342404","DOIUrl":"https://doi.org/10.1080/00365521.2024.2342404","url":null,"abstract":"Thalidomide has been used for angioectasia-associated refractory gastrointestinal bleeding (GIB), with studies showing variable efficacy and side effects profile. We conducted a meta-analysis to re...","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140612240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of serum triglyceride levels and different lipid-lowering methods on the prognosis of hypertriglyceridemic acute pancreatitis: a single-center 12-year retrospective study by propensity score matching 血清甘油三酯水平和不同降脂方法对高甘油三酯急性胰腺炎预后的影响：一项通过倾向评分匹配进行的单中心 12 年回顾性研究
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-04-16 DOI: 10.1080/00365521.2024.2342406
Yang Liu, Jian-ping Cheng, Xiao-lin Zhao
{"title":"The effect of serum triglyceride levels and different lipid-lowering methods on the prognosis of hypertriglyceridemic acute pancreatitis: a single-center 12-year retrospective study by propensity score matching","authors":"Yang Liu, Jian-ping Cheng, Xiao-lin Zhao","doi":"10.1080/00365521.2024.2342406","DOIUrl":"https://doi.org/10.1080/00365521.2024.2342406","url":null,"abstract":"To investigate the impact of triglyceride on hypertriglyceridemic acute pancreatitis (HTG-AP) and different lipid-lowering methods on triglyceride-lowering efficiency and HTG-AP.The patients with H...","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140578176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The advent of the first electric driven EUS-guided 17 gauge core needle biopsy – A pilot study on subepithelial lesions 首例电动 EUS 引导的 17 号芯针活检术的问世--上皮下病变的试点研究
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-04-15 DOI: 10.1080/00365521.2024.2336611
Fredrik Swahn, Robert Glavas, Lucin Hultin, Malin Wickbom
{"title":"The advent of the first electric driven EUS-guided 17 gauge core needle biopsy – A pilot study on subepithelial lesions","authors":"Fredrik Swahn, Robert Glavas, Lucin Hultin, Malin Wickbom","doi":"10.1080/00365521.2024.2336611","DOIUrl":"https://doi.org/10.1080/00365521.2024.2336611","url":null,"abstract":"This pilot study aimed to evaluate safety and tissue sampling from subepithelial lesions (SEL) in the upper gastrointestinal tract with a novel electric motor driven endoscopic ultrasonography (EUS...","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140578175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does surgery improve quality of life in patients with ongoing- or recurrent diverticulitis; a systematic review and meta-analysis 手术是否能改善正在发作或复发的憩室炎患者的生活质量；系统回顾和荟萃分析
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-04-13 DOI: 10.1080/00365521.2024.2337833
B. A. J. Kertzman, F. J. Amelung, H. E. Bolkenstein, E. C. J. Consten, W. A. Draaisma
{"title":"Does surgery improve quality of life in patients with ongoing- or recurrent diverticulitis; a systematic review and meta-analysis","authors":"B. A. J. Kertzman, F. J. Amelung, H. E. Bolkenstein, E. C. J. Consten, W. A. Draaisma","doi":"10.1080/00365521.2024.2337833","DOIUrl":"https://doi.org/10.1080/00365521.2024.2337833","url":null,"abstract":"Recurrences or persistent symptoms after an initial episode of diverticulitis are common, yet surgical treatment is rarely performed. Current guidelines lack clear recommendations on whether or not...","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140578174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on ‘‘study on the predictive value of pretreatment peripheral blood inflammatory markers regarding immunotherapy in patients with inoperable advanced or locally advanced oesophageal squamous cell carcinoma’’ 就 "关于无法手术的晚期或局部晚期食管鳞状细胞癌患者免疫疗法治疗前外周血炎症指标预测价值的研究 "发表评论
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-04-11 DOI: 10.1080/00365521.2024.2337840
Wenting Pan, Li Qin
{"title":"Comment on ‘‘study on the predictive value of pretreatment peripheral blood inflammatory markers regarding immunotherapy in patients with inoperable advanced or locally advanced oesophageal squamous cell carcinoma’’","authors":"Wenting Pan, Li Qin","doi":"10.1080/00365521.2024.2337840","DOIUrl":"https://doi.org/10.1080/00365521.2024.2337840","url":null,"abstract":"Published in Scandinavian Journal of Gastroenterology (Ahead of Print, 2024)","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140578172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small bowel intramural hematoma caused by warfarin: case report and literature review 华法林引起的小肠壁内血肿：病例报告和文献综述
IF 1.9 4区 医学
Scandinavian Journal of Gastroenterology Pub Date : 2024-04-10 DOI: 10.1080/00365521.2024.2337830
Zihao Wang, Tianxiang Jiang, Mingchun Mu, Chaoyong Shen, Zhaolun Cai, Haining Chen, Bo Zhang
{"title":"Small bowel intramural hematoma caused by warfarin: case report and literature review","authors":"Zihao Wang, Tianxiang Jiang, Mingchun Mu, Chaoyong Shen, Zhaolun Cai, Haining Chen, Bo Zhang","doi":"10.1080/00365521.2024.2337830","DOIUrl":"https://doi.org/10.1080/00365521.2024.2337830","url":null,"abstract":"Intramural hematoma of the small bowel is a rare yet acute gastrointestinal condition typically linked with impaired coagulation function, often posing diagnostic challenges. It is principally enco...","PeriodicalId":21461,"journal":{"name":"Scandinavian Journal of Gastroenterology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140578165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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