Revista médica del Instituto Mexicano del Seguro Social最新文献_第6页

[Neuromyelitis optica spectrum disorder in a patient with human immunodeficiency virus]. [1例人类免疫缺陷病毒患者的视神经脊髓炎谱系障碍]。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Erika Elizabeth González-Sansores, Brenda Bertado-Cortés, Daniela Alexia León-Castillo, Nallely Rubalcava-Sánchez

{"title":"[Neuromyelitis optica spectrum disorder in a patient with human immunodeficiency virus].","authors":"Erika Elizabeth González-Sansores, Brenda Bertado-Cortés, Daniela Alexia León-Castillo, Nallely Rubalcava-Sánchez","doi":"","DOIUrl":"","url":null,"abstract":"Background: Neuromyelitis optica spectrum (NMO) is an autoimmune condition with preferential target at the optic nerves and spinal cord. Although HIV infection can also cause neuritis and myelitis, the entity of HIV related to NMO has recently been elucidated, however, little is known about the context of this disease. Objective: To describe the clinical characteristics, imaging, treatment, and functional prognosis in an HIV-positive patient who developed an episode of longitudinally extensive transverse myelitis (LETM) with positive anti-AQP4 antibodies.Clinic case: 36-year-old man with a history of HIV diagnosed in 2017, on antiretroviral treatment. On March 2021 he was admitted for study due to complete spinal cord syndrome, corroborating in MRI a longitudinally extensive lesion from T8-L1, with CSF with and AQP4 seropositivity, a diagnosis of NMO was integrated by Wingerchuk criteria and rituximab is started with symptomatic improvement, objectifying it with the Expanded Disability Status Scale (EDSS) from 4 to 1.Conclusion: NMO entity related to HIV is rare, this phenomenon being classically found at the time of diagnosis or after the start of treatment when the immune system is still capable of developing an exaggerated immune response, however in the case we report the debut of NMO occurred 3 years after diagnosis, contrasting with previously reported cases, so we suggest that some other mechanisms could be involved, such as altered regulation of B cells and a direct viral effect.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"220-226"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/af/fb/04435117-61-2-220.PMC10396062.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Abdominal pain with neuropsychiatric symptoms and ventilatory failure as a presentation of acute porphyria]. [伴有神经精神症状和呼吸衰竭的腹痛是急性卟啉症的表现]。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Johan Alexander Azañero-Haro, Liliana Valeri Chambi-Pérez, Andrés Martín Alcántara-Díaz, Tatiana Edmee Piscoya-Silva, Alonso Ricardo Soto-Tarazona

{"title":"[Abdominal pain with neuropsychiatric symptoms and ventilatory failure as a presentation of acute porphyria].","authors":"Johan Alexander Azañero-Haro, Liliana Valeri Chambi-Pérez, Andrés Martín Alcántara-Díaz, Tatiana Edmee Piscoya-Silva, Alonso Ricardo Soto-Tarazona","doi":"","DOIUrl":"","url":null,"abstract":"Background: Acute intermittent porphyria (AIP) is an uncommon metabolic disease, being the most common of the acute porphyrias. The most frequent symptom is acute abdominal pain, although can be accompanied by seizures, neuro-psychiatric alterations or symmetrical motor neuropathies, which in some patients can progress to respiratory musculature paralysis.Objective: To describe an atypical presentation of acute porphyria to be considered as differential diagnoses in abdominal pain.Clinical case: We present a case of a patient with AIP, presenting acute abdomen, seizures, later developed neuropsychiatric compromise and symmetrical motor neuropathy, and was admitted to mechanical ventilation. Due to the severity of the neurological involvement, he received hemin arginate, presenting with transient hypertransaminemia, an adverse event not previously reported. The evolution was favorable, with mechanical ventilation and hospital discharge withdrawn.Conclusions: The diagnosis of AIP should be considered in cases of acute abdominal pain associated with neurological and/or psychiatric symptoms, particularly young women. The administration of hemin is considered the standard of treatment, and even late could have beneficial effects.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"227-233"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cb/d2/04435117-61-2-227.PMC10396011.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Acute hemorrhagic leukoencephalopathy. Case report]. 急性出血性白质脑病。病例报告)。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Crhistian Alejandro Aguilar-Vázquez, Alejandra Diana Raymundo-Carrillo, Nallely Denisse Ruvalcaba-Sánchez, Daniela Alexia Castillo-León, Erick Francisco Gutiérrez-Guzmán

{"title":"[Acute hemorrhagic leukoencephalopathy. Case report].","authors":"Crhistian Alejandro Aguilar-Vázquez, Alejandra Diana Raymundo-Carrillo, Nallely Denisse Ruvalcaba-Sánchez, Daniela Alexia Castillo-León, Erick Francisco Gutiérrez-Guzmán","doi":"","DOIUrl":"","url":null,"abstract":"Background: Acute hemorrhagic leukoencephalitis (AHLE) is an inflammatory disease of the brain, with a fulminant course that leads to a hemorrhagic demyelination of the central nervous system, having a poor prognosis and high mortality. Most of the times associated to crossed reactivity and molecular mimicry.Clinical case: : We present a case report of a previously healthy young woman with an acute and multifocal clinical course, preceded by a viral respiratory tract infection, followed by a rapid disease progression and a delay in the diagnosis. The clinical, neuroimaging and cerebrospinal fluid featured suggested the diagnosis of AHLE, despite efforts and management with immunosuppression and intensive care, the response to treatment was poor leaving the patient with a severe neurological impairment.Conclusion: There is little evidence regarding the clinical course and treatment of this disease, and more studies are needed to better characterize it and to provide further information about its prognosis and management. This paper gives a systematic review of the literature.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"239-244"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/05/de/04435117-61-2-239.PMC10395982.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10312761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Acute cholangitis secondary to periampullary duodenal diverticulum. Case report]. 继发于壶腹周围十二指肠憩室的急性胆管炎。病例报告)。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Verónica Elizabeth Masabanda-Celorio, Erik Daniel Alvares-Sores, Ulises Lara-Orosco

{"title":"[Acute cholangitis secondary to periampullary duodenal diverticulum. Case report].","authors":"Verónica Elizabeth Masabanda-Celorio, Erik Daniel Alvares-Sores, Ulises Lara-Orosco","doi":"","DOIUrl":"","url":null,"abstract":"Background: Periampullary duodenal diverticula are rare and pancreaticobiliary complications infrequent, however, when they are diagnosed and associated with symptoms, they warrant urgent intervention. The aim of this article is to present a clinical case of severe cholangitis secondary to the presence of a periampullary diverticulum successfully treated endoscopically.Clinical case: A 68-year-old man with a history of diabetes and hypertension, was admitted to the emergency room with symptoms of abdominal pain, fever, and tachycardia. With acute kidney injury and alterations in liver function tests, ultrasound with dilated common bile duct and gallstones. Magnetic resonance cholangiography is performed, showing duodenal diverticulum and choledocholithiasis. Antibiotic management is given, and endoscopic retrograde cholangiopancreatography is decided, finding a duodenal diverticulum with stones and pus inside, sphincterotomy, transpapillary dilation and multiple sweeps are performed. Cholecystectomy was performed 7 days later, and the patient was discharged without complications.Conclusions: In patients with signs of severe cholangitis, it is important not to delay endoscopic retrograde cholangiopancreatography, even when infrequent associated pathologies are evidenced, such as a periampullary duodenal diverticulum, since this represents the diagnostic and therapeutic method of choice with high rates of resolution in the case of an obstructive pathology of the bile duct.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"234-238"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/9d/04435117-61-2-234.PMC10395870.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Autoimmune/inflammatory syndrome induced by adjuvants. Case report]. 由佐剂引起的自身免疫/炎症综合征。病例报告)。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Sergio Ignacio Moreno-Urbina, Carla Paola Gameros-Palma, Jorge Gaspar Ramos-Estrada, Alberto Hiracheta-Torres

{"title":"[Autoimmune/inflammatory syndrome induced by adjuvants. Case report].","authors":"Sergio Ignacio Moreno-Urbina, Carla Paola Gameros-Palma, Jorge Gaspar Ramos-Estrada, Alberto Hiracheta-Torres","doi":"","DOIUrl":"","url":null,"abstract":"Background: The indiscriminate application of substances for aesthetic purposes, such as silicone in breast implants, leads to the production of common local signs such as inflammation, skin irregularities, edema, erythema, vascular neoformations, and ulcers, which can evolve into general symptoms such as fever, asthenia, weakness, arthralgia or activate the immune system abnormally, causing the appearance of autoimmune diseases. This set of signs and symptoms is called adjuvant-induced autoimmune/inflammatory syndrome.Clinical case: We present the case of a 50-year-old woman with a history of silicone-based breast implants who spontaneously developed a hemorrhagic coagulopathy, type A acquired hemophilia was documented, that is, autoantibodies against coagulation factor VIII. Thanks to the work of a multidisciplinary team, it is possible to successfully diagnose and treat the patient with bridging agents, implant removal and management of associated symptoms.Conclusion: the importance of knowing the pathology is recognized, which, although it is rare, when it occurs has a high mortality rate if it is not diagnosed and treated on time.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"251-255"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a0/dd/04435117-61-2-251.PMC10395909.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9928161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Epidemiological Panorama of Cervical Dysplasia in a First-Level Care Unit]. [一级护理单位宫颈发育不良的流行病学全景图]。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Patricia Seefoó-Jarquín, Francisca Sosa-Jurado, Paola Maycotte-González

{"title":"[Epidemiological Panorama of Cervical Dysplasia in a First-Level Care Unit].","authors":"Patricia Seefoó-Jarquín, Francisca Sosa-Jurado, Paola Maycotte-González","doi":"","DOIUrl":"","url":null,"abstract":"Background: Cervical cancer (CaCU) is the second cancer-related cause of death for women in Mexico. Early diagnosis and monitoring of patients by cervical cytology and colposcopy are currently the preferred screening methods for identification and prevention of this disease.Objective: To describe the epidemiological panorama of cervical dysplasia diagnosed in a first-level care hospital.Methods: The study was observational, retrospective, unicentric, homodemic, transversal. Records from 6,207 women who attended the General Subzone Hospital with Familiar Medicine #8 (HGSZ/UMF 8), in Tlaxcala, Mexico were analyzed. First-time cervical cytologies were analyzed from 2019 to 2021.Results: Cervical dysplasia was found in 2.6% of the patients being the most frequent type of dysplasia NIC 1. Most of the clinical characteristics of patients with dysplasia were in agreement with those of the Mexican population. Important differences were found (comorbilities, mass index, number of sexual partners, births, positivity to changes related to HPV and vaccination) between two population sets defined by age (younger and older than 40 years).Conclusions: The only factor where a tendency to be associated to type 2 and 3 dysplasia in the population younger than 40 years was the sexually active onset of life younger than 18 years, so this possible association should be evaluated in a bigger population. Our data suggests that risks factors should be evaluated separately for these age groups due to important differences regarding their clinic and epidemiological characteristics as well as changes in risk factor exposure.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"155-162"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/a3/04435117-61-2-155.PMC10395894.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10312755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Comparison of protective colostomy vs. ileostomy in rectal cancer surgery]. [直肠癌手术中保护性结肠造口与回肠造口的比较]。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

José Manuel Carlos Segura-González, Iris Isamar Tiscareño-Lozano, Arturo García-Galicia, Samantha Isabel Hernández-Muñoz, María Guadalupe Vera-Sánchez, Alejandra Nayelhi Maza-Cruz, Álvaro José Montiel-Jarquín, Ingrid Jiménez-Luna

{"title":"[Comparison of protective colostomy vs. ileostomy in rectal cancer surgery].","authors":"José Manuel Carlos Segura-González, Iris Isamar Tiscareño-Lozano, Arturo García-Galicia, Samantha Isabel Hernández-Muñoz, María Guadalupe Vera-Sánchez, Alejandra Nayelhi Maza-Cruz, Álvaro José Montiel-Jarquín, Ingrid Jiménez-Luna","doi":"","DOIUrl":"","url":null,"abstract":"Background: Rectal cancer (RC) is the 3rd most frequent one in Mexico. Protective stoma in resection and anastomosis is controversial.Objective: To compare quality of life (QoL), functional capacity (FC) and complications in rectal cancer (RC) patients with low and ultralow anterior resection (LAR and ULAR) with loop transverse colostomy (LTC) versus protective ileostomy (IP).Material and methods: Comparative, observational study in patients with RC and LTC (Group 1) or IP (Group 2) from 2018-2021. FC pre and postoperative, complications, hospital readmission (HR) and assessment by other specialty (AS) were assessed; QoL was assessed with EQ-5D by telephone. Student-t test, Chi-squared test, Mann-Whitney-U test were used.Results: Group 1: 12 patients: mean preoperative FC: ECOG 0.83, Karnofsky 91.66%; postoperative: ECOG 1, Karnofsky 89.17%. Mean postoperative QoL: index value 0.76 and health status 82.5%; HR: 25%; AS: 42%. Group 2: 10 patients: mean preoperative FC: ECOG 0.80, Karnofsky 90%; postoperative: ECOG 1.5, Karnofsky 84%. Mean postoperative QoL: index value 0.68 and health status 74%; HR: 50%; AS: 80%. Complications: 100% of sample.Conclusion: The differences in QoL, FC and complications between LTC and IP in RC patients operated with LAR/ULAR were not significant.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"133-139"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3a/d2/04435117-61-2-133.PMC10396053.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9928156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Oxytocin and vasopressin: sexual differences and clinical implications]. [催产素和加压素:性别差异和临床意义]。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Ricardo Mondragón-Ceballos, Jorgelina Barrios-De Tomasi, Leonor Estela Hernández-López

{"title":"[Oxytocin and vasopressin: sexual differences and clinical implications].","authors":"Ricardo Mondragón-Ceballos, Jorgelina Barrios-De Tomasi, Leonor Estela Hernández-López","doi":"","DOIUrl":"","url":null,"abstract":"Oxytocin and vasopressin share a similar chemical structure but have different functions. Both hormones are produced in different brain areas, are transported through the hypophyseal portal system, pass to the anterior hypophysis, and released to reach their target organs. These hormones also act as neuromodulators, where its receptors are found in the lateral septum, the middle amygdala, the hippocampus, the hypothalamus, and the brain stem. These brain structures regulate socio-sexual behaviors in vertebrates. Moreover, the oxytocinergic and the vasopressin systems are sexually different. The sexual steroids promote oxytocin release and the oxytocin receptor synthesis, as well as promoting or inhibiting vasopressin release and its receptor genetic transcription. Both neuropeptides are involved in social recognition, male-female pair bonding, aggression, and cognition. Furthermore, the disruption or malfunctioning of the oxytocin and vasopressin systems adds to the causes of some psychiatric disorders like depression, schizophrenia, autism, and borderline personality.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"196-203"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b4/86/04435117-61-2-196.PMC10395999.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9928160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Severe rhabdomyolysis associated with atorvastatin. Case report]. 严重横纹肌溶解与阿托伐他汀相关。病例报告)。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Jorge Medina-Romero, Otoniel Toledo-Salinas, Francisco Javier Reyes-Álvarez, Saira Sanjuana Gómez-Flores

{"title":"[Severe rhabdomyolysis associated with atorvastatin. Case report].","authors":"Jorge Medina-Romero, Otoniel Toledo-Salinas, Francisco Javier Reyes-Álvarez, Saira Sanjuana Gómez-Flores","doi":"","DOIUrl":"","url":null,"abstract":"Background: Dyslipidemia is a risk factor for the development of atherosclerosis and ischemic heart disease. Statins are safe drugs that are part of the routine treatment in patients with Acute Myocardial Infarction (AMI), however, rhabdomyolysis associated with severe myonecrosis due to statins can occur and associated complications such as acute kidney injury increase mortality. The main objective of this article is to report the case of a critically ill patient with AMI who presented severe statin-associated rhabdomyolysis documented with muscle biopsy.Description of the case: A 54-year-old man who presented with AMI, cardiogenic shock, and cardiorespiratory arrest requiring cardiopulmonary resuscitation, fibrinolysis, and successful salvage coronary angiography. However, he presented severe rhabdomyolysis associated with atorvastatin that required suspension of the drug and multi-organ support in a Coronary Care Unit.Conclusions: The prevalence of statin-associated rhabdomyolysis is low, however, the late elevation of CPK above 10 times its upper normal value in those patients with successful percutaneous coronary angiography should promptly draw attention, generate a diagnostic approach towards non-traumatic acquired causes of rhabdomyolysis and assess the suspension of statins.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"245-250"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/89/d4/04435117-61-2-245.PMC10395881.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10294048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Ethiology, risk factors and Whole blood viscosity index in thromboembolic venous disease]. [血栓栓塞性静脉疾病的伦理学、危险因素和全血粘度指数]。

Revista médica del Instituto Mexicano del Seguro Social Pub Date : 2023-03-01

Miguel Alejandro García-Gómez, Joaquín García-Pérez, Maria Fernanda Colorado-Cruz, Cinthya Paola López-Burgos, Berenice López-Zamora, Katia Melina León-Pérez, Héctor Antonio Solano-Cruz, María Del Pilar Cruz-Domínguez, Olga Lidia Vera-Lastra, Gabriela Medina-García

{"title":"[Ethiology, risk factors and Whole blood viscosity index in thromboembolic venous disease].","authors":"Miguel Alejandro García-Gómez, Joaquín García-Pérez, Maria Fernanda Colorado-Cruz, Cinthya Paola López-Burgos, Berenice López-Zamora, Katia Melina León-Pérez, Héctor Antonio Solano-Cruz, María Del Pilar Cruz-Domínguez, Olga Lidia Vera-Lastra, Gabriela Medina-García","doi":"","DOIUrl":"","url":null,"abstract":"Backround: Venous thromboembolic disease (VTED) is a frequent cause of hospitalization and mortality. Whole blood viscosity (WBV) participates in the pathogenesis of thrombosis.Objective: To identify the most frequent etiologies and their association with WBV index (WBVI) in hospitalized patients with VTED.Material and methods: Observational, cross-sectional, retrospective, analytical study, Group 1: cases (patients diagnosed with VTED) and Group 2: controls without thrombosis. Risk factors for VTED were described and WBVI was calculated from total proteins and hematocrit. Descriptive and inferential statistics were used with Chi-squared test, Fisher's exact test, Mann Whitney U test, bivariate and multivariate logistic regression analysis.Results: We included 146 patients and 148 controls, age 46.3 ±17.7 vs. 58 ± 18.2 years, of both sexes (female, 65.1%). The most frequent etiology was neoplastic (23.3%), followed by diseases with cardiovascular risk (17.8%). Independent risk factors for VTED were age, chronic kidney disease, presence of liver disease or solid neoplasia. WBVI was similar in patients with VTED as in those without thrombosis. We found an association of the presence of deep vein thrombosis and diseases with cardiovascular risk (p = 0.040).Conclusions: The presence of chronic kidney disease, liver disease, and solid neoplasia are independent risk factors for VTED. The WBVI is a simple and rapid diagnostic tool in the evaluation of patients with VTED.","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 2","pages":"140-146"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/a2/04435117-61-2-140.PMC10399765.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0