Guillermo Escamilla-Guerrero, Juan Carlos García-Rosales
{"title":"[Genotyping and its applications, a look to the future].","authors":"Guillermo Escamilla-Guerrero, Juan Carlos García-Rosales","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The detection of the most significant erythrocyte antigens present in each one of the individuals is fundamental when carrying out a transfusion or a transplant. Detection to date is performed by conventional serological methods through the antigen-antibody reaction. But several drawbacks may arise depending on the pathology under study, limiting the availability of blood components. Molecular methods such as genotyping is a tool that complements sensitivity and specificity and has come to revolutionize immunohematology in the blood bank, allowing not only the detection of erythrocyte antigens but also platelet antigens. These methodologies are applicable in patients and in large-scale donors, starting from the allelic variants present in each of the genes that code for the antigens of clinical interest, using microarray systems or systems based on particles labeled with specific probes or their variants that allow an analysis from the immunohematological point of view.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 Suppl 1","pages":"S37-S45"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/b4/04435117-61-Suppl1-S37.PMC10396029.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40685413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eber David Yubin Noriega-Mendoza, Paola Lira-Arriaga, Gamaliel Benítez-Arvizu
{"title":"[Systematization of interviews with altruistic blood donors during mobile campaign].","authors":"Eber David Yubin Noriega-Mendoza, Paola Lira-Arriaga, Gamaliel Benítez-Arvizu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The mobile campaigns of altruistic blood donation are one of the main actions of the Blood Bank of the Hospital de Especialidades \"Dr. Bernardo Sepúlveda Gutiérrez\". With the arrival of the new normal, after the COVID-19 pandemic, it was necessary to reactivate these actions according to the population's characteristics.</p><p><strong>Objective: </strong>To identify socio-cultural characteristics that enhance or limit voluntary or altruistic blood donation.</p><p><strong>Material and methods: </strong>Qualitative exploratory research, through a semi-structured interview with stratified sampling, universe of partial population of those attending blood donation; only altruistic donors were considered randomly, and representative proportions of the population subgroup were determined.</p><p><strong>Results: </strong>Most of the donors interviewed were preliminary donors who approached the blood donation tent without focused promotion. Health professionals showed greater identification to altruistic blood donation. Donors declared a lack of donation culture as the main factor limiting this human activity. Finally, they considered the accessibility to the blood donation tent as determinant for altruistic blood donation.</p><p><strong>Conclusions: </strong>Twelve recommendations were established to the Blood Bank, with which the intention is to propose strategies and establish research channels that increase the impact on the promotion of altruistic blood donation in future campaigns.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 Suppl 1","pages":"S19-S27"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/78/04435117-61-Suppl1-S19.PMC10396035.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40703192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Célida Duque-Molina, Ernesto Romero-Hernández, Dulce Alejandra Balandrán-Duarte, Juan Carlos Sánchez-Echeverría, Luis Johann Rodríguez-Soria, Iván de Jesús Ascencio-Montiel, Fabiana Maribel Zepeda-Arias, Guadalupe Núñez-Sánchez, Enrique Villarreal-Ríos, Ricardo Avilés-Hernández
{"title":"[Systematization of a comprehensive intervention for strengthening the COVID-19 medical care].","authors":"Célida Duque-Molina, Ernesto Romero-Hernández, Dulce Alejandra Balandrán-Duarte, Juan Carlos Sánchez-Echeverría, Luis Johann Rodríguez-Soria, Iván de Jesús Ascencio-Montiel, Fabiana Maribel Zepeda-Arias, Guadalupe Núñez-Sánchez, Enrique Villarreal-Ríos, Ricardo Avilés-Hernández","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The COVID-19 pandemic established a new challenge for health services in Mexico, which is why these services faced the challenge of responding to the affected people, by providing them services with opportunity, efficiency, effectiveness and safety. The Instituto Mexicano del Seguro Social (IMSS, Mexican Institute for Social Security) gave medical attention to the larger number of affected people: towards the end of September, 2022, 3,335,552 patients were registered, who represented 47% of the total (7,089,209) of confirmed COVID-19 cases since the beginning of the pandemic in 2020. Of all the cases treated, 295,065 (8.8%) required hospitalization. In addition of new scientific evidence and the implementation of best practices in medical care and directive management (with the general objective of improvement of the processes in hospital attention, even without an effective treatment at the time), we presented an evaluation, supervision method with a comprehensive (involving the three levels of health services) and analytic (structure, process, result and directive management components) approach. The achievement of specific goals and lines of action was established in a technical guideline with health policies for the COVID-19 medical care. These guidelines were instrumented with a standardized evaluation tool, a result dashboard and a risk assessment calculator, improving the quality of medical care and directive management by the multidisciplinary health team.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"60 Suppl 2","pages":"S142-S149"},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9300206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandra Carlota Treviño-Pérez, Alfonso Vega-Yáñez, Christian Ivan Martínez-Abarca, Guadalupe Estrada-Zarazúa, Luis Alberto Pérez-Camargo, Gabriela Borrayo-Sánchez
{"title":"[Medical Care of people living with HIV in the Instituto Mexicano del Seguro Social].","authors":"Sandra Carlota Treviño-Pérez, Alfonso Vega-Yáñez, Christian Ivan Martínez-Abarca, Guadalupe Estrada-Zarazúa, Luis Alberto Pérez-Camargo, Gabriela Borrayo-Sánchez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Infection by the human immunodeficiency virus (HIV) is apublic health problem worldwide, however, the incidence has remained relatively stable. In Mexico, around 10,000 new cases are reported each year. The Instituto Mexicano del Seguro Social (IMSS) has been a pioneer in the care of people living with HIV (PLWHA), gradually incorporating the different antiretroviral drugs (ARV). The first ARV used at the institutional level was zidovudine, in the 1990s, and later other agents were incorporated, such as protease inhibitors, drugs from the group of non-nucleoside analogs, and integrase inhibitors. In 2020, the migration to ARV schemes coformulated in a single tablet based on integrase inhibitors, which constitute a highly effective option and timely supply of drugs has been achieved in 99% of the population. In the aspect of prevention, the IMSS has also been a pioneer by being the first institution to implement HIV pre-exposure prophylaxis in 2021 at the national level and since 2022 universal post-exposure prophylaxis is available. The IMSS continues to be at the forefront incorporating the use of different management tools and instruments for the benefit of the population living with HIV. This document summarizes the history of HIV in the IMSS from the beginning of the epidemic to the present time.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"60 Suppl 2","pages":"96-102"},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9315026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Early alert of COVID-19 outbreaks to plan the response in the IMSS].","authors":"José Esteban Fernández-Gárate, Aide Jazmín González-Cruz, Jorge Zenil-Pérez, Ismael Seth Medina-Reyes, Humberto Frances-Salgado, Xóchitl Refugio Romero-Guerrero","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Instituto Mexicano del Seguro Social (IMSS) developed and implemented epidemic monitoring and modeling tools to support the organization and planning of an adequate and timely response to the COVID-19 health emergency. The aim of this article is to describe the methodology and results of the early outbreak detection tool called COVID-19 Alert. An early warning traffic light was developed that uses time series analysis and a Bayesian method of early detection of outbreaks from electronic records on COVID-19 for suspected cases, confirmed cases, disabilities, hospitalizations, and deaths. Through Alerta COVID-19, the beginning of the fifth wave of COVID-19 in the IMSS was detected in a timely manner, three weeks before the official declaration. The proposed method is aimed at generating early warnings before the start of a new wave of COVID-19, monitoring the serious phase of the epidemic, and supporting decision-making within the institution; unlike other tools that have an approach aimed at communicating risks to the community. We can conclude that the Alerta COVID-19 is an agile tool that incorporates robust methods for the early detection of outbreaks.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"60 Suppl 2","pages":"160-172"},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9315030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Claudia Espinel-Bermúdez, José Darío Martínez-Ezquerro, Karla Margarita Moreno-Tamayo, Célida Duque-Molina, Héctor Patiño-Rubio, Gabriel García-Rodríguez, Alethse de la Torre-Rosas, Michelle Herrera-Canales, Miriam Jackeline Loera-Rosales, Ana Luisa Pérez-Cardoso, Christian Arturo Zaragoza-Jiménez, Tania Villa-Reyes, Sergio Sánchez-García
{"title":"[Interinstitutional Command Mexico: organizational decision-making in the face of COVID-19].","authors":"María Claudia Espinel-Bermúdez, José Darío Martínez-Ezquerro, Karla Margarita Moreno-Tamayo, Célida Duque-Molina, Héctor Patiño-Rubio, Gabriel García-Rodríguez, Alethse de la Torre-Rosas, Michelle Herrera-Canales, Miriam Jackeline Loera-Rosales, Ana Luisa Pérez-Cardoso, Christian Arturo Zaragoza-Jiménez, Tania Villa-Reyes, Sergio Sánchez-García","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The third wave of COVID-19 in Mexico produced a high demand for hospital care, which is why it was created a multidisciplinary group to optimize decision-making: the Interinstitutional Command for the Health Sector (COISS, according to its initials in Spanish). So far, there is no scientific evidence of the COISS processes or their effect on the behavior of epidemiological indicators and the hospital care needs of the population in the context of COVID-19 in the entities involved.</p><p><strong>Objectives: </strong>To analyze the trend on epidemic risk indicators throughout the COISS group's management in the third wave of COVID-19 in Mexico.</p><p><strong>Material and methods: </strong>Mixed study: 1) non-systematic review of information from technical documents issued by COISS, 2) secondary analysis of open-access institutional databases through the description of healthcare needs of cases notified with COVID-19 symptoms, and an ecological analysis by each Mexican state on the behavior of hospital occupancy, RT-PCR positivity, and COVID-19 mortality in two-time points.</p><p><strong>Results: </strong>The COISS activity in identifying states with epidemic risk generated actions aimed at a reduction in hospital occupancy of beds, positivity by RT-PCR, and mortality from COVID-19. Conclusions: The decisions of the COISS group reduced the indicators of epidemic risk. Continuing the work of the COISS group is an urgent need.</p><p><strong>Conclusions: </strong>The decisions of the COISS group reduced the indicators of epidemic risk. Continuing the work of the COISS group is an urgent need.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"60 Suppl 2","pages":"S65-S76"},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10752518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudio Quinzaños-Fresnedo, Brendha Ríos-Castillo, Hugo César Hernández-Gordillo, Célida Duque-Molina
{"title":"[The need for paradigm change in maternal care: AMIIMSS model, scopes and challenges].","authors":"Claudio Quinzaños-Fresnedo, Brendha Ríos-Castillo, Hugo César Hernández-Gordillo, Célida Duque-Molina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Undoubtedly, great advances have been made in terms of maternal and infant morbidity and mortality. However, in Mexican Social Security System, the quality of maternal care is questionable, as reflected in proportions of cesarean births three times higher than those recommended by WHO, abandonment of exclusive breastfeeding and the fact that up to one in three women is a victim of abuse during delivery. Given this, the IMSS decides to implement the model called Integral Maternal Care AMIIMSS, focused on users experience and based on friendly obstetric care, along different stages of the reproductive process. Four pillars underpin the model, women's empowerment, infrastructure adaptation, training and adaptation of processes and standards. Although there are advances, with 73 pre-labor rooms enabled and 14,103 friendly attentions granted, there are pending tasks and challenges. In terms of empowerment, the birth plan needs to be included as an institutional practice. In terms of infrastructure adequacy, a budget is required to build and adapt friendly spaces. In addition, it is necessary to update the staffing tables and include new categories, for an adequate operation of the program. On training, the adaptation of academic plans for doctors and nurses is pending. In terms of processes and regulations, there is a lack of qualitative evaluation of the impact of the program on people's experience and satisfaction and elimination of obstetric violence.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"60 Suppl 2","pages":"119-126"},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9315028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Norma Magdalena Palacios-Jiménez, Célida Duque-Molina, Alejandro Alarcón-López, Sandra Beatriz González-Mota, Maximino Miranda-García, Francisco Paredes-Cruz, Eunice Itzel Valle-Arteaga, Antonio Reyna-Sevilla
{"title":"[Mental health: relevance of the problem, strategies and challenges to face in IMSS].","authors":"Norma Magdalena Palacios-Jiménez, Célida Duque-Molina, Alejandro Alarcón-López, Sandra Beatriz González-Mota, Maximino Miranda-García, Francisco Paredes-Cruz, Eunice Itzel Valle-Arteaga, Antonio Reyna-Sevilla","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the context of the 80th anniversary of the Instituto Mexicano del Seguro Social (IMSS), there are several health problems and challenges to be faced in relation to user population, which currently represents 42% of Mexico´s population. Among these issues, once five waves of COVID-19 infections have passed and mortality rates have decreased, mental and behavioral disorders stand out as a re-emerging and priority problem. In response to this, in 2022 the Mental Health Comprehensive Program (MHCP, 2021-2024) materialized, which represents, for the first time, the opportunity to provide health services that address mental disorders and addictions of user´s population IMSS, under the Primary Health Care model. That is, prioritizing health promotion, risk factors prevention, screening, timely diagnosis, and not just hospitalization and drug supply. Among the MHCP strategies, which motivated the writing of this document, we highlight the availability of reliable data, through the census of mental and behavioral disorders, related to important characteristics in terms of population, state, hospital, prevalence of disorders, in order to act accordingly through the infrastructure and human resources available at the IMSS, with emphasis on the first level of care.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"60 Suppl 2","pages":"S150-S159"},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9300204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco Javier Picó-Guzmán, Olga Georgina Martínez-Montañez, Enrique Ruelas-Barajas, Mauricio Hernández-Ávila
{"title":"[The estimated economic impact of cardiovascular and diabetes mellitus complications 2019-2028].","authors":"Francisco Javier Picó-Guzmán, Olga Georgina Martínez-Montañez, Enrique Ruelas-Barajas, Mauricio Hernández-Ávila","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>In Mexico, diabetes mellitus (DM) and diseases cardiovascular, register an upward trend.</p><p><strong>Objective: </strong>To estimate the number of complications due to cardiovascular events (CVD) and complications derived from DM (CDM) accumulated in beneficiaries of the Mexican Institute of Social Security (IMSS) from 2019 to 2028, as well as the expense for medical and economic benefits in a scenario baseline and one of change in metabolic profile due to lack of medical follow-up during the COVID-19 pandemic.</p><p><strong>Material and methods: </strong>The number of CVD and CDM was estimated from 2019, with a 10-year risk projection using the ESC CVD Risk Calculator and United Kingdom Prospective Diabetes Study, considering risk factors registered in the institutional databases.</p><p><strong>Results: </strong>From 2019 to 2028, cumulative CVD cases were estimated at 2 million and those of CDM in 960 thousand, with an impact on medical spending of 439,523 million pesos and on the economic benefits of 174,085 millions. When considering the COVID-19 pandemic, CVD events and CDM increased by 589 thousand, with an increase in spending of 93,787 million pesos for medical care and 41,159 million for economic benefits.</p><p><strong>Conclusions: </strong>Without a comprehensive intervention in the management of CVD and CDM, the cost by both diseases will continue to increase, with financial pressures getting older.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"60 Suppl 2","pages":"S86-S95"},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9315025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[PRIISMA Project: Transformation into a more preventive, resilient, comprehensive, innovative, sustainable, modern and accessible IMSS].","authors":"Célida Duque-Molina, Gabriela Borrayo-Sánchez, Ricardo Avilés-Hernández, Paulina Herrera-Reyna","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two years after the onset of the COVID-19 pandemic, the Mexican Institute for Social Security (IMSS, according to its initials in Spanish) rethought new projects focused on the new needs of the population and social security organizations and institutions. The Institute, as a cornerstone in the search for the wellbeing of Mexicans, aligned with the National Development Plan and the Strategic Health for Wellbeing Program, sought to direct its transformation towards a preventive, resilient, comprehensive, innovative, sustainable, modern and accessible IMSS. For this reason, the Medical Services Director designed the PRIISMA Project, as the one that over the next three years could make possible to innovate and improve its medical care processes, starting with the recovery of medical services and identifying those groups of beneficiaries who experience the most vulnerable circumstances. The PRIISMA project consisted of five sub-projects: 1. Vulnerable groups; 2. Efficient and effective care; 3. Prevent IMSS plus; 4 IMSS University and 5. Recovery of medical services. The strategies of each project seek to improve medical care for all IMSS beneficiaries and users with a human rights perspective and by priority groups; the goal is reducing the gaps in access to health care, leaving no one behind and leaving no one out; and to surpass the goals for medical services provided before the pandemic. This document provides an overview of strategies and progress of the PRIISMA sub-projects achieved during 2022.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"60 Suppl 2","pages":"S54-S64"},"PeriodicalIF":0.0,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9315024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}