Omid Kajian, Hussein Islami, Mohammad Reza Dehghani Ashkazari
{"title":"A Model for Promoting a Culture of Organ Donation in the Production of Programs in the National Media.","authors":"Omid Kajian, Hussein Islami, Mohammad Reza Dehghani Ashkazari","doi":"10.4103/sjkdt.sjkdt_577_20","DOIUrl":"https://doi.org/10.4103/sjkdt.sjkdt_577_20","url":null,"abstract":"<p><p>The media has an important and decisive role in creating a culture of organ donation and promoting community health, but there is no effort to identify the elements of the programming framework in this field in the national media of Iran. Given the great importance of this issue, this study examined the development of a framework to promote a culture of organ donation in the production of programs in the national media of Iran. This qualitative study involved a content analysis of six TV programs. The dialog and images related to these programs were extracted on the basis of the semiotic method. The results of this research were classified into two categories of motivational factors (referring to cultural and religious motives, scientific and educational facts, references to gratitude and moral motives, differences in different situations and diseases, attention to legal regulations, encouragement to receive an organ donation card and statistics of transplant status in the country) and barriers (patients' personal barriers, media insufficiencies, cultural barriers, educational and scientific barriers, medical insufficiencies and administrative insufficiencies). The results of this study showed that in order to promote a culture of organ donation in the production of programs in the national media, two categories of motivational factors and barriers should be.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"66-72"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seçil Conkar Tunçay, A Keskinoğlu, I K Bulut, E Levent, G Hakverdi, C Kabasakal
{"title":"Can a Cardiovascular Scoring System be Used to Determine Cardiovascular Disease in Pediatric Dialysis Patients?","authors":"Seçil Conkar Tunçay, A Keskinoğlu, I K Bulut, E Levent, G Hakverdi, C Kabasakal","doi":"10.4103/sjkdt.sjkdt_501_21","DOIUrl":"https://doi.org/10.4103/sjkdt.sjkdt_501_21","url":null,"abstract":"<p><p>We created a two scoring systems for pediatric dialysis patients to determine the presence of cardiovascular disease (CVD) which are referred to as (CVDS)-1 and CVDS-2. We included 25 patients on hemodialysis (n = 19) and peritoneal dialysis (n = 6). CVDS-1 and CVDS-2 use multiple parameters, to determine the presence of CVD in pediatric dialysis patients. The scoring systems include renal pathology, nutrition, dialysis adequacy, residual urine output, protein catabolism, dialysis modality and some laboratory values. CVD evaluations included the left ventricular mass index, pulse wave velocity and carotid intima-media thickness measurements. The mean age was 11.1 ± 6.51 years, and the male-female ratio was 14:11. Patients on peritoneal dialysis had higher serum levels of calcium × phosphorus product and diastolic blood pressure (P = 0.013 and P = 0.006, respectively). We did not find any significant correlation between peritoneal dialysis and hemodialysis patients in the CVDS-1 and CVDS-2 scores (P >0.005). The CVDS-1 system had a sensitivity of 90% and a specificity 80%. The CVDS-2 system had a sensitivity of 90% and a specificity 66%. Additionally, the area under the receiver operating characteristic curve of CVDS-1 was 0.913 (95% confidence interval (CI) = 0.80-1.00, P <0.001) for a diagnosis of CVD and that of CVDS-2 was 0.86 (95% CI = 0.72-1.00, P <0.001). We believe that CVDS-1 will be more successful in determining the presence of CVD with the biochemical parameters we use in clinical practice on a monthly basis.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"26-33"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitrios Patoulias, Christodoulos Papadopoulos, Asterios Karagiannis, Michael Doumas
{"title":"Effects of Long-Term Use of Sodium-Glucose Co-Transporter-2 Inhibitors on Proteinuria and Renal Function in Patients with Type 2 Diabetes Mellitus without Chronic Kidney Disease during the COVID-19 Pandemic.","authors":"Dimitrios Patoulias, Christodoulos Papadopoulos, Asterios Karagiannis, Michael Doumas","doi":"10.4103/sjkdt.sjkdt_605_21","DOIUrl":"10.4103/sjkdt.sjkdt_605_21","url":null,"abstract":"","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"107-109"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilizing Nephrotoxic Medications and Starting Renal Replacement Therapies in Acute Settings: A Single-Center Retrospective Study.","authors":"Ohoud Aljuhani, Raneem Bukhari, Huda Aljedaani, Asmaa Alamoudi","doi":"10.4103/sjkdt.sjkdt_141_21","DOIUrl":"https://doi.org/10.4103/sjkdt.sjkdt_141_21","url":null,"abstract":"<p><p>Acute kidney injury (AKI) is common in hospitalized patients, and it is associated with higher mortality and morbidity. Drug-induced kidney disease (DIKD) accounts for approximately 8-60% of hospitalized patients and 14-28% in intensive care unit patients. Nephrotoxic agents are one of the possible causes of AKI in acute settings. Most previous studies have identified the relationship between utilizing nephrotoxic medications and the rate of AKI. Limited literature has addressed the relationship between nephrotoxic medications and the need to start renal replacement therapy (RRT). The main aim of this study was to assess the correlation between the use of nephrotoxic medications and the initiation of RRT in acute settings. This retrospective cohort study included adult hospitalized patients older than 18 years at a tertiary academic center who had received one of the following medications for more than 24 hours: angiotensin II receptor blockers, angiotensin-converting enzyme inhibitors (ACEIs), thiazide, amphotericin B, aminoglycoside, vancomycin, piperacillin/tazobactam, colistin, acyclovir, cisplatin, and methotrexate. In total, 86 patients were included in this study; 25 (29%) developed AKI, and only 15 (17.4%) required RRT. Piperacillin/tazobactam (P = 0.01), vancomycin (P = 0.02), and ACEIs (P = 0.02) were the most common nephrotoxic drugs prescribed in patients who required RRT. Hospitalized patients receiving vancomycin, piperacillin/tazobactam, or ACEIs had higher chances of starting RRT. Identifying patients at risk of drug-induced kidney disease is crucial to prevent the need for RRT.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"10-17"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Lakshmanna, N Harini Devi, Aparna R Bitla, Alok Sachan, V Sivakumar, Pvln Srinivasa Rao
{"title":"Evaluation of Four Novel Biomarkers for Diagnosing of Normoalbuminuric Diabetic Nephropathy in a South Indian Population.","authors":"N Lakshmanna, N Harini Devi, Aparna R Bitla, Alok Sachan, V Sivakumar, Pvln Srinivasa Rao","doi":"10.4103/sjkdt.sjkdt_252_21","DOIUrl":"https://doi.org/10.4103/sjkdt.sjkdt_252_21","url":null,"abstract":"<p><p>Microalbuminuria, expressed as the urinary albumin-creatinine ratio (UACR), is currently the gold standard for detecting diabetic nephropathy. However, because of its low sensitivity and larger variability, there is a need for novel biomarkers. Although promising, these novel markers require further assessment before achieving clinical utility. The assessment of combined urinary biomarkers is also being explored. Changes in urinary nephrin (uNephrin), urinary podocalyxin (uPCX), urinary N-acetyl-β-glucosaminidase (uNAG) and urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (u8-oxodG) were estimated in healthy controls and in patients with Type 2 diabetes mellitus (T2DM) with and without microalbuminuria. In total, 30 T2DM patients with normoalbuminuria and 30 with microalbuminuria, alongside 30 healthy individuals, were recruited. Plasma glucose, creatinine, UACR, uNAG uPCX, uNephrin and u8-oxodG were estimated. The urinary markers were corrected for creatinine. Estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration formula. All the urinary markers except uPCX showed a statistically significant increase in T2DM patients with normoalbuminuria compared with the controls (P <0.05). UACR was found to have positive correlations with all the urinary markers, whereas eGFR showed a negative correlation. All urinary markers except uPCX showed a statistically significant area under the curve (0.810 for uNephrin; 0.906 for uNAG); 0.828 for u8-oxodG) with good sensitivity and specificity. Combining the markers did not show any additional advantage in their diagnostic performance. Our study shows the importance of including tubular injury markers and their utility in combination with glomerular injury markers for early detection of diabetic renal injury before microalbuminuria sets in.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"34-47"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Veysel Erol, Mevlüt Çeri, Mehmet Mert, Oğuz Kılıç, İsmail Doğu Kılıç, İbrahim Hasbey, Nuran Sabır, Süleyman Demir, Ayşen Kardeşler, Belda Dursun
{"title":"The Relationship of Renalase with Diurnal Blood Pressure Rhythm, Left Ventricular Mass Index and Carotid Intima-media Thickness in Autosomal Dominant Polycystic Kidney Disease.","authors":"Veysel Erol, Mevlüt Çeri, Mehmet Mert, Oğuz Kılıç, İsmail Doğu Kılıç, İbrahim Hasbey, Nuran Sabır, Süleyman Demir, Ayşen Kardeşler, Belda Dursun","doi":"10.4103/sjkdt.sjkdt_110_21","DOIUrl":"https://doi.org/10.4103/sjkdt.sjkdt_110_21","url":null,"abstract":"<p><p>This study investigated the relationship between renalase and diurnal blood pressure (BP) rhythm, left ventricular mass index (LVMI) and carotid intima-media thickness (IMT) in autosomal dominant polycstic kidney disease (ADPKD) patients. The study included 59 ADPKD patients and 36 healthy volunteers. Renalase, noradrenalin, adrenaline, creatinine (Cr) and spot urine microalbumin-Cr ratio were studied; 24-h ambulatory BP and carotid IMT were measured, and LVMI was calculated. The ADPKD group comprised 21 hypertensive and 38 normotensive patients, and the control group comprised 36 healthy participants. Renalase levels were significantly higher in hypertensive and normotensive ADPKD patients than in the control group (69.7 ± 90.02 ng/mL and 91.93 ± 106.55 ng/mL vs. 16.9 ± 51.4 ng/mL; P = 0.042 and P = 0.001, respectively). The renalase levels were higher in the hypertensive ADPKD group than in the normotensive ADPKD group but they were not statistically significant (91.93 ± 106.55 ng/mL vs. 69.7 ± 90.02 ng/mL; P = 0.486). LVMI was significantly higher in the hypertensive ADPKD group compared with the normotensive ADPKD and control groups (92.2 ± 20.9 vs. 76.2 ± 16.89 and 68.6 ± 12.75; P = 0.02 and P = 0.001, respectively). There was no statistically significant difference in carotid IMT between the groups (0.59 ± 0.16, 0.65 ± 0.17 and 0.58±0.1; P = 0.442, respectively). Renalase levels were significantly higher in the normotensive ADPKD and hypertensive ADPKD groups compared with the control group, but its relationship with circadian BP rhythm, LVMI and carotid IMT was not demonstrated.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"58-65"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sonographic Assessment of Renal Length in Healthy Bangladeshi Children.","authors":"Agomoni Chaki, Abdullah Mamun, Tahmina Jesmin, Amitava Biswas, Syed Saimul Hauque, Afroza Begum, Md Rahman, Ranjit Ranjan Roy, Golam Uddin","doi":"10.4103/sjkdt.sjkdt_423_21","DOIUrl":"https://doi.org/10.4103/sjkdt.sjkdt_423_21","url":null,"abstract":"<p><p>Renal size is an important parameter used for the clinical evaluation of renal growth and renal diseases in children. Renal length is the most useful parameter for measuring renal size. Therefore, establishing the normal value of renal length in children is valuable, as it can serve as a baseline for the diagnosis of renal diseases and possible interventions. The objective of our study was to assess renal length in Bangladeshi children by ultrasonography. This cross-sectional study was carried out in the Department of Pediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, from January 2019 to June 2020. In total, 369 apparently healthy children aged 1 month to 18 years were included in this study. Renal length was measured by ultrasonography by same experienced radiologist. The mean renal length ± standard deviation was calculated for each age group. The correlation of renal length with age and anthropometric parameters was tested using Pearson's correlation test. No statistical difference was found in renal length between the two sexes. The left kidney was significantly longer than the right kidney (P <0.001). There were strong positive correlations of renal length with age and anthropometric parameters. The best positive correlation was found between renal length and height (r = 0.95 and 0.94 for the right and left kidneys, respectively). Linear regression equations were obtained to predict the renal length from age and anthropometric parameters. Renal length has a strong positive correlation with body length/height.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"1-9"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benson's Relaxation Method for Patients Undergoing Hemodialysis: A Useful Complementary Method to Alleviate Depression and Anxiety.","authors":"Nader Aghakhani","doi":"10.4103/sjkdt.sjkdt_287_21","DOIUrl":"10.4103/sjkdt.sjkdt_287_21","url":null,"abstract":"","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"110-111"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eda Altun, Bülent Kaya, Saime Paydas, Mustafa Balal
{"title":"Peritoneal Dialysis in Heart Failure that Resists Standard Treatment: A Single-center Experience.","authors":"Eda Altun, Bülent Kaya, Saime Paydas, Mustafa Balal","doi":"10.4103/sjkdt.sjkdt_437_21","DOIUrl":"https://doi.org/10.4103/sjkdt.sjkdt_437_21","url":null,"abstract":"<p><p>Peritoneal dialysis (PD) has been reported as a long-term maintenance treatment of refractory congestive heart failure (RCHF). In this study, we aimed to evaluate the outcome of 24 PD patients with RCHF and Stage IV chronic kidney disease. The continuous ambulatory PD program consisted of two or three exchanges daily and one exchange nightly. In the follow-up period, clinical and echocardiographic biochemical findings and the need for hospitalization were recorded. Fifteen patients (66.7%) were male, and the mean age was 62.75 years. Under the PD treatment, the average daily urine volume and ultrafiltration of the patients were 800-1000 mL and 1000-15,000 mL, respectively. Ten patients were followed for 24 months and eight patients were followed for 12 months. During the follow-up period, there was a regression in the New York Heart Association heart failure class (from Class IV to Class II in 18 patients), and a decrease in body weights and an increase in serum sodium levels in all patients. Only two patients were hospitalized for cardiovascular disease over 2 years. During the follow-up period, one patient was transferred to hemodialysis because of peritonitis. In conclusion, in patients with RCHF and chronic renal failure without dialysis, PD in addition to standard treatment may be a safe treatment choice.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"73-80"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chakraborti Annesha, Swarnim Swarnim, Mantan Mukta, Vineeta Vijay Batra
{"title":"Nonsteroidal Anti-Inflammatory Drug-Induced Granulomatous Interstitial Nephritis in Juvenile Idiopathic Arthritis: A Rare Entity.","authors":"Chakraborti Annesha, Swarnim Swarnim, Mantan Mukta, Vineeta Vijay Batra","doi":"10.4103/sjkdt.sjkdt_397_21","DOIUrl":"https://doi.org/10.4103/sjkdt.sjkdt_397_21","url":null,"abstract":"<p><p>Granulomatous interstitial nephritis (GIN) is rare in childhood and is associated with poor outcomes. We report a 6-year-old girl who developed nephrotic-range proteinuria following chronic non-steroidal anti-inflammatory drug (NSAID) use for juvenile idiopathic arthritis (JIA). Other possible etiologies were ruled out, and the diagnosis of GIN was confirmed by renal biopsy. NSAIDs were henceforth withheld and prednisolone was started, which resulted in amelioration of proteinuria. Strong suspicion, quick diagnosis and early initiation of therapy improve the outcome in GIN and prevents or delays kidney failure.</p>","PeriodicalId":21356,"journal":{"name":"Saudi Journal of Kidney Diseases and Transplantation","volume":"36 1-6","pages":"81-84"},"PeriodicalIF":0.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}