Revista Paulista De Pediatria最新文献

Respiratory system parameters in children with low severity cystic fibrosis: is there early involvement in relation to healthy peers? 低度囊性纤维化儿童的呼吸系统参数：与健康儿童相比，是否存在早期参与？

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-12-11 DOI: 10.1590/1984-0462/2024/42/2023030

Gabriela Castilhos Ducati, Juliana Cardoso, Elaine Paulin Ferrazeane, C. Schivinski

{"title":"Respiratory system parameters in children with low severity cystic fibrosis: is there early involvement in relation to healthy peers?","authors":"Gabriela Castilhos Ducati, Juliana Cardoso, Elaine Paulin Ferrazeane, C. Schivinski","doi":"10.1590/1984-0462/2024/42/2023030","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023030","url":null,"abstract":"ABSTRACT Objective: To compare and analyze pulmonary function and respiratory mechanics parameters between healthy children and children with cystic fibrosis. Methods: This cross-sectional analytical study included healthy children (HSG) and children with cystic fibrosis (CFG), aged 6–13 years, from teaching institutions and a reference center for cystic fibrosis in Florianópolis/SC, Brazil. The patients were paired by age and sex. Initially, an anthropometric evaluation was undertaken to pair the sample characteristics in both groups; the medical records of CFG were consulted for bacterial colonization, genotype, and disease severity (Schwachman-Doershuk Score — SDS) data. Spirometry and impulse oscillometry were used to assess pulmonary function. Results: In total, 110 children were included, 55 in each group. In the CFG group, 58.2% were classified as excellent by SDS, 49.1% showed the ΔF508 heterozygotic genotype, and 67.3% were colonized by some pathogens. Statistical analysis revealed significant differences between both groups (p<0.05) in most pulmonary function parameters and respiratory mechanics. Conclusions: Children with cystic fibrosis showed obstructive ventilatory disorders and compromised peripheral airways compared with healthy children. These findings reinforce the early changes in pulmonary function and mechanics associated with this disease.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138584348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatricians’ focus of sight at pain assessment during a neonatal heel puncture 儿科医生在新生儿足跟穿刺时评估疼痛的视线焦点

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-12-11 DOI: 10.1590/1984-0462/2024/42/2023089

Erica Souza Silva, Marina C. M. Barros, Julia Baptista Lopes Borten, L. Carlini, R. Balda, R. Orsi, T. Heiderich, C. Thomaz, R. Guinsburg

{"title":"Pediatricians’ focus of sight at pain assessment during a neonatal heel puncture","authors":"Erica Souza Silva, Marina C. M. Barros, Julia Baptista Lopes Borten, L. Carlini, R. Balda, R. Orsi, T. Heiderich, C. Thomaz, R. Guinsburg","doi":"10.1590/1984-0462/2024/42/2023089","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023089","url":null,"abstract":"ABSTRACT Objective: To evaluate the focus of pediatricians’ gaze during the heel prick of neonates. Methods: Prospective study in which pediatricians wearing eye tracker glasses evaluated neonatal pain before/after a heel prtick. Pediatricians scored the pain they perceived in the neonate in a verbal analogue numerical scale (0=no pain; 10=maximum pain). The outcomes measured were number and time of visual fixations in upper face, lower face, and hands, in two 10-second periods, before (pre) and after the puncture (post). These outcomes were compared between the periods, and according to pediatricians’ pain perception: absent/mild (score: 0–5) and moderate/intense (score: 6–10). Results: 24 pediatricians (31 years old, 92% female) evaluated 24 neonates. The median score attributed to neonatal pain during the heel prick was 7.0 (Interquartile range: 5–8). Compared to pre-, in the post-periods, more pediatricians fixed their gaze on the lower face (63 vs. 92%; p=0.036) and the number of visual fixations was greater on the lower face (2.0 vs. 5.0; p=0.018). There was no difference in the number and time of visual fixations according to the intensity of pain. Conclusions: At bedside, pediatricians change their focus of attention on the neonatal face after a painful procedure, focusing mainly on the lower part of the face.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138584290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute exogenous intoxications in childhood: factors related to hospitalization 儿童急性外源性中毒：与住院治疗有关的因素

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-12-11 DOI: 10.1590/1984-0462/2024/42/2023028

Juliana Gabriela Burgardt Werner, V. Platt

{"title":"Acute exogenous intoxications in childhood: factors related to hospitalization","authors":"Juliana Gabriela Burgardt Werner, V. Platt","doi":"10.1590/1984-0462/2024/42/2023028","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023028","url":null,"abstract":"ABSTRACT Objective: To describe the profile of children assisted in the Emergency Room of a Children reference Hospital in the South of Brazil, victims of acute poisoning between 2016 and 2021, to characterize the toxic agents and to present the factors related to hospitalization. Methods: Retrospective, descriptive and observational study with data collection from medical records at a children’s hospital from July 2016 to June 2021 based on the compulsory notification forms. The characteristics of victims, of the incident, the type and class of the substance involved, the procedures demanded and the need for the Intensive Care Unit were evaluated. The outcome considered was hospitalization. Absolute and relative frequencies were calculated for the categorical variables and measures of central tendency and dispersion for the numerical ones. Binary logistic regression was performed to identify variables related to hospitalization. Results: There were 411 consultations, with the mean age of 7.2±5.5 years, and predominance of females (59.9%). Most of the poisoning occurred at home (82.1%) and orally (93.7%). Chemicals or cleaning products were the main agents in children up to 1 year of age, whereas in the other age groups accidents occurred most frequently with medicines. Hospital admission occurred in 38.7% of the cases, with related variables being: number of agents, type of substance involved, medication that acts on the Central Nervous System, recurrence, motivation (accidental/intentional), and performance of simple exams. Conclusions: More preventive actions are needed, such as legislation, as well as greater guidance to parents on how to store products in the domestic environment, in order to reduce the number of exogenous intoxications in the pediatric population.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138584554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patau and Edwards Syndromes in a University Hospital: beyond palliative care 大学医院的帕陶综合征和爱德华兹综合征：超越姑息关怀

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-12-11 DOI: 10.1590/1984-0462/2024/42/2023053

Ligia Marçola, Ivete Zoboli, Rita Tiziana Verardo Polastrini, S. Barbosa, Mário Cícero Falcão, Paula de Vicenzi Gaiolla

{"title":"Patau and Edwards Syndromes in a University Hospital: beyond palliative care","authors":"Ligia Marçola, Ivete Zoboli, Rita Tiziana Verardo Polastrini, S. Barbosa, Mário Cícero Falcão, Paula de Vicenzi Gaiolla","doi":"10.1590/1984-0462/2024/42/2023053","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023053","url":null,"abstract":"ABSTRACT Objective: To describe the newborn population with Patau (T13) and Edwards Syndrome (T18) with congenital heart diseases that stayed in the Intensive Care Unit (ICU) of a quaternary care hospital complex, regarding surgical and non-surgical medical procedures, palliative care, and outcomes. Methods: Descriptive case series conducted from January/2014 to December/2018 through analysis of records of patients with positive karyotype for T13 or T18 who stayed in the ICU of a quaternary hospital. Descriptive statistics analysis was applied. Results: 33 records of eligible patients were identified: 27 with T18 (82%), and 6 T13 (18%); 64% female and 36% male. Eight were preterm infants with gestational age between 30–36 weeks (24%), and only 4 among the 33 infants had a birth weight >2500 g (12%). Four patients underwent heart surgery and one of them died. Intrahospital mortality was 83% for T13, and 59% for T18. The majority had other malformations and underwent other surgical procedures. Palliative care was offered to 54% of the patients. The median hospitalization time for T18 and T13 was 29 days (range: 2–304) and 25 days (13–58), respectively. Conclusions: Patients with T13 and T18 have high morbidity and mortality, and long hospital and ICU stays. Multicentric studies are needed to allow the analysis of important aspects for creating protocols that, seeking therapeutic proportionality, may bring better quality of life for patients and their families.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138584506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of maternal knowledge of solar exposure and vitamin D in the neonatal period 评估产妇对新生儿期日晒和维生素 D 的了解程度

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-12-11 DOI: 10.1590/1984-0462/2024/42/2023040

Sandra Mara Witkowski, Catarina Pfitzer, Emanueli Rudolf, Gabriela de Souza, Aline Didoni Fajardo, Flávia Maestri Nobre Albini, Fabricio Sbroglio Lando, Marco Otilio Duarte Rodrigues Wilde

{"title":"Assessment of maternal knowledge of solar exposure and vitamin D in the neonatal period","authors":"Sandra Mara Witkowski, Catarina Pfitzer, Emanueli Rudolf, Gabriela de Souza, Aline Didoni Fajardo, Flávia Maestri Nobre Albini, Fabricio Sbroglio Lando, Marco Otilio Duarte Rodrigues Wilde","doi":"10.1590/1984-0462/2024/42/2023040","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023040","url":null,"abstract":"ABSTRACT Objective: To assess mothers’ knowledge on sun exposure related to serum vitamin D levels in the neonatal period. Methods: Observational, analytical and cross-sectional study, carried out from August 2020 to May 2021 through a questionnaire directed to mothers of newborns, in a maternity hospital in Southern Brazil. Results: From 141 interviewees, 132 (93.6%) believe it is important to expose the neonate to sun, 101 (71.6%) think this exposure can increase vitamin D levels, 86 (61%) received such information from a doctor, 108 (76.6%) believe there are no risks of sun exposure, 88 (62.4%) claim it isn´t necessary to use any kind of protection, 96 (68.1%) said that only exposure to the sun was necessary to maintain adequate levels of vitamin D during the neonatal period. Only two mothers (1.4%) claim that you should not exposure the neonate to the sun, and only one (0.7%) stated that sun expose can cause skin problems. Conclusions: Most mothers lack satisfactory knowledge about sun exposure related to serum vitamin D levels in the neonatal period. The need to inform and clarify the population about sun exposure during this period is remarkable, in addition to disseminating the proper way to maintain serum levels of vitamin D.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138584380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between childhood anthropometric indicators and bone mineral density in adulthood 儿童时期人体测量指标与成年后骨矿物质密度之间的关系

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-10-23 DOI: 10.1590/1984-0462/2024/42/2023026

M. C. M. D. Freitas, Julio Cesar da Costa, Cynthia Correa Lopes Barbosa, Lidyane Ferreira Zambrin, C. Romanzini, M. Romanzini, E. R. Ronque

{"title":"Association between childhood anthropometric indicators and bone mineral density in adulthood","authors":"M. C. M. D. Freitas, Julio Cesar da Costa, Cynthia Correa Lopes Barbosa, Lidyane Ferreira Zambrin, C. Romanzini, M. Romanzini, E. R. Ronque","doi":"10.1590/1984-0462/2024/42/2023026","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023026","url":null,"abstract":"ABSTRACT Objective: This study aimed to verify the association between childhood anthropometric indicators and areal bone mineral density (aBMD) in adulthood. Methods: Repeated measures of 137 subjects (68 females) were obtained in childhood (9.2±1.5 years of age) and adulthood (22.3±1.7 years of age). aBMD (g/cm 2 ) was assessed for whole body, lumbar spine, upper and lower limbs, and femoral neck in adulthood using dual-energy X-ray absorptiometry. Anthropometric measurements of body weight (BW), height, triceps and subscapular skinfolds were obtained in childhood. The anthropometric indicators used were BW, body mass index (BMI), and sum of skinfolds (ΣSF). Simple linear regression was used to assess the association between childhood anthropometric indicators and aBMD in adulthood, controlled by chronological age and stratified by sex, with 5% statistical significance. Results: In females, multiple associations were observed between anthropometric indicators and aBMD, with higher coefficients for BMI (β=0.020; R 2 =0.20; p<0.01 for right femoral neck to β=0.008; R 2 =0.16; p<0.01 for upper limbs), followed by BW (β=0.003; R 2 =0.21; p<0.01 for upper limbs to β=0.008; R 2 =0.20; p<0.01 for right femoral neck) and ΣSF (β=0.001; R 2 =0.06; p<0.01 for upper limbs to β=0.005; R 2 =0.12; p<0.01 for right femoral neck). In males, associations were observed only for the lumbar spine region (β=0.016; R 2 =0.09 for BMI to β=0.004; R 2 =0.06; p<0.01 for ΣSF). Conclusions: Anthropometric indicators of childhood proved to be sensitive predictors of aBMD in adulthood, especially in females. BMI indicated a greater association with aBMD in both sexes.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139315004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuberculosis in adolescence: an integrative review focusing on patient-centered care 青少年肺结核：注重以患者为中心的护理的综合评论

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-10-23 DOI: 10.1590/1984-0462/2024/42/2023027

Clara Carvalho Mendes, Roberto José Gervásio Unger, T. Araújo-Jorge, A. C. C. Carvalho

引用次数: 0

Ankyloglossia severity in infants: maternal pain, self-efficacy, and functional aspects of breastfeeding 婴儿口唇强直的严重程度：母亲的疼痛、自我效能感和母乳喂养的功能方面

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-10-23 DOI: 10.1590/1984-0462/2024/42/2022203

C. L. C. Batista, Alex Luiz Pozzobon Pereira

{"title":"Ankyloglossia severity in infants: maternal pain, self-efficacy, and functional aspects of breastfeeding","authors":"C. L. C. Batista, Alex Luiz Pozzobon Pereira","doi":"10.1590/1984-0462/2024/42/2022203","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2022203","url":null,"abstract":"ABSTRACT Objective: To analyze functional aspects of breastfeeding, self-efficacy, and pain reported by mothers during breastfeeding, in newborns with severe and mild ankyloglossia. Methods: This is an observational study, carried out with 81 babies with ankyloglossia, assessed by the Bristol Tongue Assessment Tool (severe: scores 0–3; mild: scores 4–6) nested in a cohort carried out at the University Hospital of the Federal University of Maranhão, São Luis, Brazil. The functional aspects of breastfeeding were analyzed using the Breastfeeding Observation Form of the United Nations Children's Fund (BOF-UNICEF) and the LATCH Scoring System. Breastfeeding self-efficacy was measured using the Breastfeeding Self-Efficacy Scale — Short-Form. Pain indicators were evaluated by the Short-Form McGill Pain Questionnaire. The significance level adopted was 5%. Results: Maternal age was 26.7±0.8 years, and 64.2% reported high school education. Most babies were male (67.9%), and the birth weight was 3232±60g. A significant association was detected in the sucking aspect evaluated by the BOF-UNICEF [β=0.22 (95%CI 0.07; 0.73), p-value=0.013]. However, the groups did not differ in the assessment of breastfeeding performed by the LATCH scale. The groups had no differences in the assessment of breastfeeding self-efficacy reported by mothers, and in pain scores. Conclusions: Despite the observation of sucking difficulty in infants with severe ankyloglossia., the quality of breastfeeding in general, maternal pain, and self-efficacy reported by mothers do not differ when compared with infants with mild ankyloglossia. Therefore, the severity of ankyloglossia seems not to affect the breastfeeding indicators.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139315040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporal trends in vaccination coverage in the first year of life in Brazil 巴西婴儿出生后第一年疫苗接种覆盖率的时间趋势

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-10-23 DOI: 10.1590/1984-0462/2024/42/2023020

Ana Beatriz Batista Neves, Lucas Silva, Gabriela Morais Celestino Amaral, Maria de Lourdes Nascimento da Silva, Claudio José dos Santos Júnior

{"title":"Temporal trends in vaccination coverage in the first year of life in Brazil","authors":"Ana Beatriz Batista Neves, Lucas Silva, Gabriela Morais Celestino Amaral, Maria de Lourdes Nascimento da Silva, Claudio José dos Santos Júnior","doi":"10.1590/1984-0462/2024/42/2023020","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023020","url":null,"abstract":"ABSTRACT Objective: The aim of this study was to analyze the temporal trends in vaccination coverage (VC) during the first year of life of children in Brazil. Methods: Data on VC for the first year of life from 2011 to 2020 for Bacille Calmette-Guerin (BCG), hepatitis B, polio, pentavalent, and triple viral vaccines at the national, regional, and state levels were obtained from the Information System of the National Immunization Program. Trends were analyzed using Prais-Winsten generalized linear regression models and average annual percent change (APC) estimates. Results: Decreasing trends were observed for the BCG (APC −3.58%; p<0.05), pentavalent (APC −4.10%; p<0.05), polio (APC −2.76%; p<0.05), and triple viral (APC −2.56%; p<0.05) vaccines in the country. Hepatitis B vaccine was the only vaccine that displayed stationary behavior (APC −4.22%; p>0.05). During the study period, no increasing trends were observed in any territory or vaccine. Conclusions: This study shows a recent significant reduction and decreasing trends in VC during the first year of life of children in Brazil, indicating the need for interventions to curb this ongoing phenomenon and to recover acceptable VC rates in the country.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139315419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barriers to medication adherence by caregivers of children with leukemia: an observational study 白血病患儿照顾者坚持用药的障碍：一项观察研究

IF 1.7

Revista Paulista De Pediatria Pub Date : 2023-10-23 DOI: 10.1590/1984-0462/2024/42/2022214

Fernanda Alves França, Ana Catarina Fernandes Figueredo, Luiza Tessmann, V. Tiziani, José Carlos Martins Córdoba, Isis Magalhães, N. U. L. Tavares, Patrícia Medeiros-Souza

{"title":"Barriers to medication adherence by caregivers of children with leukemia: an observational study","authors":"Fernanda Alves França, Ana Catarina Fernandes Figueredo, Luiza Tessmann, V. Tiziani, José Carlos Martins Córdoba, Isis Magalhães, N. U. L. Tavares, Patrícia Medeiros-Souza","doi":"10.1590/1984-0462/2024/42/2022214","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2022214","url":null,"abstract":"ABSTRACT Objective: To identify barriers to adherence to home oral maintenance chemotherapy in children with leukemia treated at a specialized cancer center. Methods: We used the Brief Medication Questionnaire (BMQ) as a tool for screening barriers to adherence. The level of adherence was calculated considering at least one positive response in each BMQ domain, defined as Regimen Screen, Belief Screen, and Recall Screen. A positive screening for belief barriers (PSB) indicates that the caregiver reports not understanding the medication's mechanism of action and adverse effects. Results: Three important barriers to adherence were identified: beliefs, number of children of the caregiver, and age of the caregiver. The primary caregivers included 32 mothers (80%), four fathers (10%), three grandmothers (7.5%), and one unrelated caregiver (2.5 %). Most caregivers with a PSB were mothers. A PSB indicates that the caregiver reports not understanding the medication's mechanism of action and adverse effects. Caregivers with two or more children (median, three) had more barriers to adherence. Caregivers with potential non-adherence tended to be older than those with potential adherence, although without statistical significance (p=0.079, Mann-Whitney U test). Conclusions: The main barriers to adherence to home oral maintenance chemotherapy in children with leukemia identified through interviews with their caregivers, most often mothers, were lack of understanding of the treatment regimen, a greater number of children, and older age.","PeriodicalId":21311,"journal":{"name":"Revista Paulista De Pediatria","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139314951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0