白血病患儿照顾者坚持用药的障碍:一项观察研究

IF 1.4 Q3 PEDIATRICS
Fernanda Alves França, Ana Catarina Fernandes Figueredo, Luiza Tessmann, V. Tiziani, José Carlos Martins Córdoba, Isis Magalhães, N. U. L. Tavares, Patrícia Medeiros-Souza
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引用次数: 0

摘要

摘要 目的找出在一家专业癌症中心接受治疗的白血病患儿在坚持家庭口服维持化疗过程中遇到的障碍。方法:采用简短用药问卷(BMQ)作为研究工具:我们使用简要用药问卷(BMQ)作为筛查依从性障碍的工具。计算依从性水平时考虑了 BMQ 各领域中至少一个阳性反应,即 "疗程筛查"、"信念筛查 "和 "回忆筛查"。信念障碍筛查(PSB)呈阳性表示护理人员不了解药物的作用机制和不良反应。结果:确定了影响坚持用药的三个重要障碍:信念、护理人员的子女人数和护理人员的年龄。主要照顾者包括 32 名母亲(80%)、4 名父亲(10%)、3 名祖母(7.5%)和 1 名无关照顾者(2.5%)。大多数有 PSB 的照顾者是母亲。有 PSB 表示照护者不了解药物的作用机制和不良反应。有两个或两个以上子女(中位数为三个)的护理人员在坚持用药方面遇到的障碍较多。有可能不坚持用药的护理人员往往比有可能坚持用药的护理人员年龄大,但无统计学意义(P=0.079,Mann-Whitney U 检验)。结论通过对白血病患儿的护理人员(多为母亲)进行访谈,发现患儿坚持家庭口服维持化疗的主要障碍是对治疗方案缺乏了解、患儿人数较多以及年龄较大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Barriers to medication adherence by caregivers of children with leukemia: an observational study
ABSTRACT Objective: To identify barriers to adherence to home oral maintenance chemotherapy in children with leukemia treated at a specialized cancer center. Methods: We used the Brief Medication Questionnaire (BMQ) as a tool for screening barriers to adherence. The level of adherence was calculated considering at least one positive response in each BMQ domain, defined as Regimen Screen, Belief Screen, and Recall Screen. A positive screening for belief barriers (PSB) indicates that the caregiver reports not understanding the medication's mechanism of action and adverse effects. Results: Three important barriers to adherence were identified: beliefs, number of children of the caregiver, and age of the caregiver. The primary caregivers included 32 mothers (80%), four fathers (10%), three grandmothers (7.5%), and one unrelated caregiver (2.5 %). Most caregivers with a PSB were mothers. A PSB indicates that the caregiver reports not understanding the medication's mechanism of action and adverse effects. Caregivers with two or more children (median, three) had more barriers to adherence. Caregivers with potential non-adherence tended to be older than those with potential adherence, although without statistical significance (p=0.079, Mann-Whitney U test). Conclusions: The main barriers to adherence to home oral maintenance chemotherapy in children with leukemia identified through interviews with their caregivers, most often mothers, were lack of understanding of the treatment regimen, a greater number of children, and older age.
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来源期刊
Revista Paulista De Pediatria
Revista Paulista De Pediatria Medicine-Pediatrics, Perinatology and Child Health
CiteScore
2.30
自引率
0.00%
发文量
100
审稿时长
11 weeks
期刊介绍: The Revista Paulista de Pediatria publishes original contributions, case reports and review of clinical research with methodological approach in the areas of health and disease of neonates, infants, children and adolescents. The objective is to disseminate research with methodological quality on issues that comprise the health of children and adolescents. All articles are freely available online, via SciELO. Its abbreviated title is Rev. Paul. Pediatr., which should be used in bibliographies, footnotes and bibliographical references and strips.
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