Temporal trends in vaccination coverage in the first year of life in Brazil

IF 1.4 Q3 PEDIATRICS
Ana Beatriz Batista Neves, Lucas Silva, Gabriela Morais Celestino Amaral, Maria de Lourdes Nascimento da Silva, Claudio José dos Santos Júnior
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Abstract

ABSTRACT Objective: The aim of this study was to analyze the temporal trends in vaccination coverage (VC) during the first year of life of children in Brazil. Methods: Data on VC for the first year of life from 2011 to 2020 for Bacille Calmette-Guerin (BCG), hepatitis B, polio, pentavalent, and triple viral vaccines at the national, regional, and state levels were obtained from the Information System of the National Immunization Program. Trends were analyzed using Prais-Winsten generalized linear regression models and average annual percent change (APC) estimates. Results: Decreasing trends were observed for the BCG (APC −3.58%; p<0.05), pentavalent (APC −4.10%; p<0.05), polio (APC −2.76%; p<0.05), and triple viral (APC −2.56%; p<0.05) vaccines in the country. Hepatitis B vaccine was the only vaccine that displayed stationary behavior (APC −4.22%; p>0.05). During the study period, no increasing trends were observed in any territory or vaccine. Conclusions: This study shows a recent significant reduction and decreasing trends in VC during the first year of life of children in Brazil, indicating the need for interventions to curb this ongoing phenomenon and to recover acceptable VC rates in the country.
巴西婴儿出生后第一年疫苗接种覆盖率的时间趋势
摘要 目的本研究旨在分析巴西儿童出生后第一年内疫苗接种覆盖率(VC)的时间趋势。研究方法从国家免疫计划信息系统中获取了 2011 年至 2020 年期间全国、地区和州一级的卡介苗、乙肝疫苗、脊髓灰质炎疫苗、五联疫苗和三联病毒疫苗出生后第一年的接种率数据。使用普拉伊斯-温斯顿广义线性回归模型和年均百分比变化 (APC) 估计值对趋势进行了分析。结果显示卡介苗呈下降趋势(APC -3.58%;P0.05)。在研究期间,没有观察到任何地区或疫苗呈上升趋势。结论:这项研究表明,巴西儿童在出生后第一年内接种的 VC 最近明显减少,并呈下降趋势,这表明有必要采取干预措施来遏制这一持续存在的现象,并恢复该国可接受的 VC 接种率。
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来源期刊
Revista Paulista De Pediatria
Revista Paulista De Pediatria Medicine-Pediatrics, Perinatology and Child Health
CiteScore
2.30
自引率
0.00%
发文量
100
审稿时长
11 weeks
期刊介绍: The Revista Paulista de Pediatria publishes original contributions, case reports and review of clinical research with methodological approach in the areas of health and disease of neonates, infants, children and adolescents. The objective is to disseminate research with methodological quality on issues that comprise the health of children and adolescents. All articles are freely available online, via SciELO. Its abbreviated title is Rev. Paul. Pediatr., which should be used in bibliographies, footnotes and bibliographical references and strips.
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