Revista espanola de cardiologia最新文献

{"title":"Clasificación, prevalencia y riesgo cardiovascular de los diferentes tipos de hipercolesterolemia","authors":"Fernando Civeira ,&nbsp;Estíbaliz Jarauta ,&nbsp;Victoria Marco-Benedí ,&nbsp;Ana M. Bea ,&nbsp;Rocío Mateo-Gallego ,&nbsp;Itziar Lamiquiz-Moneo ,&nbsp;Irene Gracia-Rubio ,&nbsp;Daniel Bello-Álvarez ,&nbsp;Martín Laclaustra ,&nbsp;María Teresa Tejedor ,&nbsp;Salvador Olmos ,&nbsp;Ana Cenarro","doi":"10.1016/j.recesp.2025.07.007","DOIUrl":"10.1016/j.recesp.2025.07.007","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The frequency, clinical characteristics and risk of atherosclerotic cardiovascular disease (ASCVD) of the different types of hypercholesterolemia are not well established. The primary and secondary objectives of this study were to determine the cause of hypercholesterolemia and whether the cause confers a different ASCVD prognosis.</div></div><div><h3>Methods</h3><div>The analysis included 3474 probands with primary hypercholesterolemia, of whom 3283 (94.8%) were followed up for 9.33<!--> <!-->± 5.8 years for ASCVD. Genetic analysis of familial hypercholesterolemia (FH) genes, polygenic risk score for hypercholesterolemia, and lipid concentrations, including lipoprotein(a), were used to classify hypercholesterolemia.</div></div><div><h3>Results</h3><div>The diagnoses were heterozygous FH, n<!--> <!-->=<!--> <!-->400 (11.5%); hyperlipoproteinemia(a), n<!--> <!-->=<!--> <!-->181 (5.2%); polygenic hypercholesterolemia, n<!--> <!-->=<!--> <!-->434 (12.5%); hyperlipoproteinemia(a) plus polygenic hypercholesterolemia, n<!--> <!-->=<!--> <!-->128 (3.7%); multifactorial, n<!--> <!-->=<!--> <!-->1562 (45.0%); and idiopathic, n<!--> <!-->=<!--> <!-->769 (22.1%). At baseline, low-density lipoprotein cholesterol levels were higher in heterozygous FH, and the prevalence of ASCVD was higher in hyperlipoproteinemia(a). Other clinical and biochemical characteristics did not differ among hypercholesterolemia subgroups. The survival rate was lower in participants with hyperlipoproteinemia(a) than in the other hypercholesterolemia groups (<em>P</em> <!-->=<!--> <!-->.001). Variables independently associated with ASCVD events during follow-up were age, male sex, the presence of ASCVD, diabetes or hypertension at baseline, current smoking, lipoprotein(a) concentration, and high-density lipoprotein cholesterol concentration, the latter being inversely associated with ASCVD events. Total mortality was independent of the type of hypercholesterolemia.</div></div><div><h3>Conclusions</h3><div>Genetic hypercholesterolemia has a worse prognosis for ASCVD than nongenetic hypercholesterolemia. Among individuals with genetic hypercholesterolemia, those with elevated lipoprotein(a) have the worst prognosis. Conventional lipid-lowering treatment for low-density lipoprotein cholesterol appears to be less effective in hypercholesterolemia due to hyperlipoproteinemia(a) than in other forms of hypercholesterolemia.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 131-141"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menos stents para el IAMCEST: ¿está listo el balón farmacoactivo para su gran momento?","authors":"Bruno Scheller","doi":"10.1016/j.recesp.2025.08.007","DOIUrl":"10.1016/j.recesp.2025.08.007","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 106-107"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tratamiento con balón farmacoactivo frente a tratamiento con stent farmacoactivo para lesiones coronarias únicas difusas de novo","authors":"Eun-Seok Shin ,&nbsp;Sunwon Kim ,&nbsp;Dong Oh Kang ,&nbsp;Bitna Kim ,&nbsp;Ae-Young Her","doi":"10.1016/j.recesp.2025.07.004","DOIUrl":"10.1016/j.recesp.2025.07.004","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>There are limited data on drug-coated balloon (DCB) treatment for de novo diffuse coronary artery disease (CAD). This study aimed to evaluate the clinical impact of DCB-based percutaneous coronary intervention (PCI) in patients with de novo diffuse long CAD.</div></div><div><h3>Methods</h3><div>We retrospectively included 623 patients with single de novo diffuse CAD (≥ 30<!--> <!-->mm). These patients underwent PCI exclusively for the target lesion and were successfully treated with DCB-based PCI. They were compared with 623 propensity-matched patients who underwent conventional PCI with second-generation drug-eluting stents (DES) for diffuse CAD (DES-only group). The primary endpoint was major adverse cardiovascular events (MACE), defined as a composite of cardiac death, myocardial infarction, stent or target lesion thrombosis, target vessel revascularization, and major bleeding at 2 years.</div></div><div><h3>Results</h3><div>In the DCB-based group, 73.7% of patients were treated with DCB alone. The MACE rate was significantly lower in the DCB-based group than in the DES-only group (4.6% vs 14.6%; HR, 0.29; 95%<span>C</span>I, 0.18-0.47; <em>P</em> <!-->&lt;<!--> <!-->.001). Rates of target vessel revascularization (3.1% vs 9.7%; <em>P</em> <!-->&lt;<!--> <!-->.001) and major bleeding events (0.8% vs 2.7%; <em>P</em> <!-->=<!--> <!-->.008) were also lower with DCB-based PCI than with DES-only PCI. In a multivariable model, DCB-based PCI was independently associated with a lower risk of 2-year MACE, target vessel revascularization, and major bleeding.</div></div><div><h3>Conclusions</h3><div>In patients with de novo diffuse CAD, DCB-based PCI was associated with a significant reduction in MACE compared with DES-only PCI</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 108-116"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Miocardiopatía por TTN: expandiendo la relevancia clínica más allá de la banda A","authors":"María Valverde-Gómez ,&nbsp;Luis De La Higuera-Romero ,&nbsp;Marlene Pérez-Barbeito ,&nbsp;Soledad García-Hernández ,&nbsp;Ivonne Cárdenas-Reyes ,&nbsp;Juan Pablo Ochoa","doi":"10.1016/j.recesp.2025.06.008","DOIUrl":"10.1016/j.recesp.2025.06.008","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 184-186"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrección en el artículo de Molina-Lerma et al. «Registro español de marcapasos. XXI informe oficial de la Asociación del Ritmo Cardiaco de la Sociedad Española de Cardiología (2023)», Rev Esp Cardiol. 2024;77:947–956","authors":"","doi":"10.1016/j.recesp.2025.11.001","DOIUrl":"10.1016/j.recesp.2025.11.001","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Page 191"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146034445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacto de la contaminación por partículas finas (PM2,5) en la frecuentación y mortalidad hospitalaria por infarto agudo de miocardio en España","authors":"Raquel Campuzano ,&nbsp;Julio Núñez ,&nbsp;Violeta Sánchez ,&nbsp;Juan José Gómez-Doblas ,&nbsp;Vicente Arrarte ,&nbsp;Ángel Cequier ,&nbsp;Blanca Miranda ,&nbsp;Cristina Fernández ,&nbsp;Náyade Prado ,&nbsp;Nicolás Rosillo ,&nbsp;José Luis Bernal ,&nbsp;Pablo Pérez ,&nbsp;Sonia Gutiérrez ,&nbsp;Jordi Bañeras","doi":"10.1016/j.recesp.2025.06.010","DOIUrl":"10.1016/j.recesp.2025.06.010","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Atherosclerotic vascular disease is the main cause of mortality attributable to air pollution. This study analyzes, for the first time, the association between levels of fine particulate matter (PM_2.5, particles ≤ 2.5<!--> <!-->μm in diameter) and hospital admissions and in-hospital mortality due to acute myocardial infarction (AMI) in hospitals of the Spanish National Health System.</div></div><div><h3>Methods</h3><div>Data on air pollution, temperature, and humidity were obtained from the Ministry for the Ecological Transition and the Demographic Challenge, covering the period from 2016 to 2021. A total of 122 National Health System hospitals were geographically matched with environmental monitoring stations located within a 10<!--> <!-->km radius. The study included 115 071 patients aged 18 years or older (mean age, 67 years; 28% women) who were discharged with a diagnosis of AMI during the study period. An autoregressive integrated moving average (ARIMA) model was applied to each hospital, and a meta-analysis was conducted to consolidate the estimates of the association between PM_2.5 levels and variations in AMI hospital admissions. The association between PM_2.5 pollution and in-hospital AMI mortality was analyzed using logistic regression models.</div></div><div><h3>Results</h3><div>Maximum 3-day average PM_2.5 levels exceeding 10<!--> <!-->μg/m³ were associated with an additional 21.9 AMI hospital admissions per 1000 (95%CI, 9.1-34.8; <em>P</em> <!-->&lt;<!--> <!-->.001). Furthermore, PM_2.5 levels above 25<!--> <!-->μg/m³ (3-day moving average) were associated with an increased risk of in-hospital mortality due to AMI (OR, 1.14; 95%CI, 1.07-1.23; <em>P<!--> </em>&lt;<!--> <!-->.001).</div></div><div><h3>Conclusions</h3><div>This study identifies a significant association between elevated PM_2.5 levels and increased hospital admissions and in-hospital mortality due to AMI in Spain, highlighting the importance of reducing air pollution as a critical factor in cardiovascular health.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 117-127"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prueba sistemática de expansión de tripletes en pacientes con síndrome de Brugada genéticamente negativo","authors":"Alexis Hermida ,&nbsp;Guillaume Jedraszak ,&nbsp;Flavie Ader ,&nbsp;Philippe Maury ,&nbsp;Philippe Charron ,&nbsp;Estelle Gandjbakhch","doi":"10.1016/j.recesp.2025.04.011","DOIUrl":"10.1016/j.recesp.2025.04.011","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 178-180"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estrategia de seguridad en la extracción de electrodos de dispositivos cardiacos","authors":"Javier Miguelena Hycka ,&nbsp;Victoria Cañadas-Godoy ,&nbsp;Piercarmine Iorlano Mariano ,&nbsp;Víctor Castro Urda ,&nbsp;Diego Monzón Díaz ,&nbsp;Jorge Rodríguez-Roda Stuart","doi":"10.1016/j.recesp.2025.06.006","DOIUrl":"10.1016/j.recesp.2025.06.006","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 1","pages":"Pages 92-94"},"PeriodicalIF":5.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145824167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corazón de hierro: miocardiopatía secundaria a hepatopatía","authors":"María Fernández García ,&nbsp;Andrés Castaño-García ,&nbsp;Luis Gutiérrez de la Varga","doi":"10.1016/j.recesp.2025.08.015","DOIUrl":"10.1016/j.recesp.2025.08.015","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 1","pages":"Pages 97-98"},"PeriodicalIF":5.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145824215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aumento de la mortalidad cardiovascular en personas con discapacidad. Un nuevo reto que hay que afrontar","authors":"Pedro Armario ,&nbsp;Montserrat Martín-Baranera","doi":"10.1016/j.recesp.2025.05.014","DOIUrl":"10.1016/j.recesp.2025.05.014","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 1","pages":"Pages 13-14"},"PeriodicalIF":5.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145824173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}