Katarzyna Gendera , Stanimir Georgiev , Andreas Eicken , Andrea Amici , Alfred Hager , Maria von Stumm , Daniel Dilber , Peter Ewert , Pinar Bambul Heck
{"title":"Implante de stent para la estenosis recurrente tras la reparación del arco aórtico en niños pequeños: resultados a corto y medio plazo sin reintervenciones","authors":"Katarzyna Gendera , Stanimir Georgiev , Andreas Eicken , Andrea Amici , Alfred Hager , Maria von Stumm , Daniel Dilber , Peter Ewert , Pinar Bambul Heck","doi":"10.1016/j.recesp.2025.07.002","DOIUrl":"10.1016/j.recesp.2025.07.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Stent implantation has become the gold standard for the treatment of native coarctation of the aorta (CoA) and recurrent CoA in adolescents and adults. In smaller children, however, stent implantation remains technically challenging due to anatomical constraints and growth considerations. Furthermore, data on the optimal treatment strategy in this age group are still limited. This study retrospectively analyzed clinical outcomes in young children treated with <em>stent</em> implantation for recurrent aortic arch stenosis.</div></div><div><h3>Methods</h3><div>A total of 101 patients (63 male; 62%) with a body weight of less than 15<!--> <!-->kg were treated with endovascular <em>stent</em> implantation for restenosis of the reconstructed aortic arch (n<!--> <!-->=<!--> <!-->94; 93%) or native CoA (n<!--> <!-->=<!--> <!-->7; 7%). The median age at the time of stent implantation was 4.8 months (IQR, 3.2-9.6 months) with a median body weight of 5.9<!--> <!-->kg (IQR, 4.7-8.4<!--> <!-->kg). The median follow-up period was 46.4 months (IQR, 11.0-76.6 months).</div></div><div><h3>Results</h3><div>All procedures were successful, and no serious complications occurred. The peak-to-peak gradient decreased significantly from a median of 32.5<!--> <!-->mmHg (IQR, 17.3-46.0<!--> <!-->mmHg) to 0.0<!--> <!-->mmHg (IQR, 0.0-2.5<!--> <!-->mmHg; <em>P</em> <!--><<!--> <!-->.005). The diameter of the narrow segment increased from a median of 3.0<!--> <!-->mm (IQR, 2.0-4.0<!--> <!-->mm) to 6.9<!--> <!-->mm (IQR, 6.0-8.0<!--> <!-->mm; <em>P</em> <!--><<!--> <!-->.005). During follow-up, none of the patients required reoperation</div></div><div><h3>Conclusions</h3><div>Stent implantation is a safe and feasible treatment option in patients with restenosis after complex aortic arch reconstruction or native CoA in whom surgical treatment would pose an elevated risk of complications. However, repeated dilatations and, ultimately, intentional stent fracture are required during follow-up.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 142-150"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inteligencia artificial (IA): …y otra de cal","authors":"Fernando A. Navarro","doi":"10.1016/j.recesp.2025.08.016","DOIUrl":"10.1016/j.recesp.2025.08.016","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Page 99"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146034446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Sanz-Sánchez , Sandra Santos Martínez , Eva Rumiz González , Juan Francisco Oteo Domínguez , David Tejada Ponce , Antonio Gómez Menchero , Guillermo Sánchez Elvira , Georgina Fuertes Ferre , Fernando Rivero Crespo , Antonela Lukic Otanovic , José Díaz Fernández , Eladio Galindo Fernández , Cristóbal Urbano Carrillo , Neus Salvatella Giralt , Mauricio Torres Sánchez , Arturo García Touchard , Borja Ibáñez Cabeza , Giulio Stefanini , Fernando Alfonso Manterola , Héctor García García , Ignacio J. Amat-Santos
{"title":"Estrategia de reducción de stents frente a revascularización coronaria percutánea convencional en el IAMCEST: diseño del ensayo COPERNICAN","authors":"Jorge Sanz-Sánchez , Sandra Santos Martínez , Eva Rumiz González , Juan Francisco Oteo Domínguez , David Tejada Ponce , Antonio Gómez Menchero , Guillermo Sánchez Elvira , Georgina Fuertes Ferre , Fernando Rivero Crespo , Antonela Lukic Otanovic , José Díaz Fernández , Eladio Galindo Fernández , Cristóbal Urbano Carrillo , Neus Salvatella Giralt , Mauricio Torres Sánchez , Arturo García Touchard , Borja Ibáñez Cabeza , Giulio Stefanini , Fernando Alfonso Manterola , Héctor García García , Ignacio J. Amat-Santos","doi":"10.1016/j.recesp.2025.05.006","DOIUrl":"10.1016/j.recesp.2025.05.006","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Primary percutaneous coronary intervention (PCI) with drug-eluting stent implantation (DES) is the standard of treatment in patients presenting with ST-segment elevation myocardial infarction (STEMI). However, target lesion failure can occur due to stent underexpansion, malapposition, hypersensitivity, fracture, and neoatherosclerosis. Drug-coated balloons (DCB) represent a potential alternative supported by the concept of “leaving nothing behind.” The aim is to compare a reduced stent strategy based on DCB- with DES-PCI in patients presenting with STEMI.</div></div><div><h3>Methods</h3><div>Prospective, pragmatic, multicenter, noninferiority, randomized clinical trial.</div></div><div><h3>Results</h3><div>A total of 1 272 patients presenting with STEMI will be randomized to any paclitaxel-DCB vs any sirolimus-DES (both with CE approval) for all culprit and nonculprit lesions during PCI. The primary endpoint will be target-lesion failure: cardiac death, target-vessel myocardial infarction, or ischemia-driven target lesion revascularization at 12-month follow-up. An independent clinical events committee masked to treatment allocation will adjudicate all suspected events. Clinical follow-up will be performed after 1 month (30 days<!--> <!-->±<!--> <!-->5 days) and 1 year (365 days<!--> <!-->±<!--> <!-->30 days). An extended follow-up at 3, 5, and 10 years is planned.</div></div><div><h3>Conclusions</h3><div>The COPERNICAN trial will be the first randomized study comparing clinical outcomes of DCB vs DES in STEMI patients.</div><div>ClinicalTrials.gov: <span><span>NCT06353594</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 100-105"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhangyu Lin , Xuejing Duan , Yuetang Wang , Qian Wang , Lei Jia , Kefei Dou
{"title":"Recurrencia rápida de reestenosis coronaria inexplicada en el stent (RECUR): una nueva enfermedad inflamatoria coronaria con evidencia patológica","authors":"Zhangyu Lin , Xuejing Duan , Yuetang Wang , Qian Wang , Lei Jia , Kefei Dou","doi":"10.1016/j.recesp.2025.04.014","DOIUrl":"10.1016/j.recesp.2025.04.014","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 180-184"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Vitolo , Marco Proietti , Marta Mantovani , Jacopo Francesco Imberti , Davide Antonio Mei , Niccolò Bonini , Giulio Francesco Romiti , Bernadette Corica , Igor Diemberger , Laurent Fauchier , Francisco Marín , Gheorghe-Andrei Dan , Tatjana S. Potpara , Gregory Y.H. Lip , Giuseppe Boriani
{"title":"Actividad física en pacientes con fibrilación auricular y eventos adversos: resultados de un estudio de cohortes prospectivo multicéntrico europeo","authors":"Marco Vitolo , Marco Proietti , Marta Mantovani , Jacopo Francesco Imberti , Davide Antonio Mei , Niccolò Bonini , Giulio Francesco Romiti , Bernadette Corica , Igor Diemberger , Laurent Fauchier , Francisco Marín , Gheorghe-Andrei Dan , Tatjana S. Potpara , Gregory Y.H. Lip , Giuseppe Boriani","doi":"10.1016/j.recesp.2025.07.010","DOIUrl":"10.1016/j.recesp.2025.07.010","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Increased physical activity may improve outcomes in patients with atrial fibrillation (AF), but available data are limited. This study aimed to analyze the association between physical activity and major adverse outcomes in a large European AF cohort.</div></div><div><h3>Methods</h3><div>We used data from a prospective, observational, large-scale multicenter study of AF in European patients, involving 27 countries and 250 centers. Patients self-reported their physical activity levels during the preceding 2 years, categorized as none (physically inactive), occasional, regular, or intense. The primary outcome was a composite of major adverse cardiovascular (CV) events and all-cause mortality.</div></div><div><h3>Results</h3><div>A total of 9525 patients with AF were included (median age 71 years; 41% female). Overall, 43% reported being physically inactive. Among those who reported physical activity, 56.9% described it as occasional, 36.5% as regular, and 6.6% as intense. Inactive patients had a higher burden of both CV and non-CV comorbidities. Over a median follow-up of 728 days, 16.2% of the patients experienced the primary composite endpoint. Physical activity was independently associated with a lower risk of the primary endpoint (adjusted HR, 0.68; 95% CI, 0.59-0.76), with a progressively lower incidence as activity levels increased. Interaction analyses showed that the beneficial effect of physical activity was consistent among several subgroups, with no significant interactions.</div></div><div><h3>Conclusions</h3><div>Physical activity, even at low levels, was associated with a reduced incidence of CV events and all-cause mortality. These benefits appear to be independent of CV risk factors and comorbidities, highlighting the importance of incorporating physical activity into holistic AF management strategies.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 151-164"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto Domínguez-Rodríguez , Daniel Hernández-Vaquero , Néstor Baéz-Ferrer
{"title":"La amenaza invisible: la contaminación del aire ya es el segundo factor de riesgo de mortalidad en la población general","authors":"Alberto Domínguez-Rodríguez , Daniel Hernández-Vaquero , Néstor Baéz-Ferrer","doi":"10.1016/j.recesp.2025.07.011","DOIUrl":"10.1016/j.recesp.2025.07.011","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 128-130"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validación de la secuencia de resonancia magnética 3D de única apnea ESSOS para el estudio de la dilatación aórtica","authors":"Sandra Gómez-Talavera , Álvaro Navarro-Guzmán , Rodrigo Fernández-Jiménez , Valentín Fuster , Javier Sánchez-González , Borja Ibáñez","doi":"10.1016/j.recesp.2025.04.009","DOIUrl":"10.1016/j.recesp.2025.04.009","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 175-178"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Margarida G. Figueiredo, José Miguel Viegas, Sílvia Aguiar Rosa
{"title":"Miocardiopatía hipertrófica con obstrucción intracavitaria secuencial resuelta con mavacamten","authors":"Margarida G. Figueiredo, José Miguel Viegas, Sílvia Aguiar Rosa","doi":"10.1016/j.recesp.2025.08.002","DOIUrl":"10.1016/j.recesp.2025.08.002","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 2","pages":"Pages 187-188"},"PeriodicalIF":5.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}