{"title":"Bono le chien, nouvelle mascotte des urgences de Fribourg.","authors":"Thomas Schmutz, Jessica Schwaller","doi":"10.53738/REVMED.2024.20.891.1905","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.891.1905","url":null,"abstract":"","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"20 891","pages":"1905"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Un décanat au service de l’égalité hommes-femmes.","authors":"Stéphanie Hugues","doi":"10.53738/REVMED.2024.20.891.1896","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.891.1896","url":null,"abstract":"","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"20 891","pages":"1896-1897"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Émeline Maisonneuve, Alice Panchaud, David Baud, Mathilde Gavillet
{"title":"[Neonatal Fc receptor : role and implications in maternal fetal medicine].","authors":"Émeline Maisonneuve, Alice Panchaud, David Baud, Mathilde Gavillet","doi":"10.53738/REVMED.2024.20.891.1869","DOIUrl":"10.53738/REVMED.2024.20.891.1869","url":null,"abstract":"<p><p>During pregnancy, the mother's IgG immunoglobulins cross the -placenta via the neonatal Fc receptor (FcRn), enabling the fetus to acquire passive immunity. In the presence of maternal allo- or auto-antibodies, placental transfer of these pathogenic antibodies mediated by FcRn can cause diseases in the fetus and/or the newborn. FcRn blockade therefore appears to be a therapeutic strategy in these high-risk pregnancies, firstly by reducing IgG recycling, -thereby reducing its concentration in the maternal circulation, and secondly by blocking placental transfer. The promising results of a recent trial testing nipocalimab, a monoclonal antibody targeting FcRn, in very severe erythrocyte alloimmunisation, has opened the way to new targeted therapeutic approaches for perinatal diseases mediated by maternal IgG.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"20 891","pages":"1869-1873"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Current management of advanced high grade serous ovarian carcinomas].","authors":"Yves Durand, Marie Nicod Lalonde, Delfyne Hastir, Anastasia Astarita, Patrice Mathevet","doi":"10.53738/REVMED.2024.20.891.1848","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.891.1848","url":null,"abstract":"<p><p>Ovarian cancers are gynecological cancers with a poor prognosis. Most ovarian cancers are high-grade serous carcinomas. It is now accepted that they are very often tubal in origin. Their management has undergone major advances in recent years. Their clinical manifestations are not very specific, and no screening test has yet -proved its worth, which explains why they are often diagnosed late. The diagnostic phase is essentially based on ultrasound and abdomino-pelvic CT scans, for reasons of ease of access. Other -examination modalities, such as MRI and above all PET-Ct, are playing an increasingly important role in the initial management of extension or thera-peutic follow-up. Even with notable advances in diagnosis and treatment, the overall prognosis remains poor.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"20 891","pages":"1848-1854"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Faire le lien entre recherches clinique et fondamentale.","authors":"Serge Ferrari","doi":"10.53738/REVMED.2024.20.891.1903","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.891.1903","url":null,"abstract":"","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"20 891","pages":"1903"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Baud, Manon Vouga, Begoña Martinez De Tejada
{"title":"Les épidémies successives et leurs conséquences sur la grossesse : ce n’est pas fini….","authors":"David Baud, Manon Vouga, Begoña Martinez De Tejada","doi":"10.53738/REVMED.2024.20.891.1845","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.891.1845","url":null,"abstract":"","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"20 891","pages":"1845-1846"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Océane Pécheux, Luca Pesenti, Begoña Martinez De Tejada, Bénédicte Le Tinier
{"title":"[Pregnancies at advanced maternal age].","authors":"Océane Pécheux, Luca Pesenti, Begoña Martinez De Tejada, Bénédicte Le Tinier","doi":"10.53738/REVMED.2024.20.891.1874","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.891.1874","url":null,"abstract":"<p><p>The definition of advanced maternal age (AMA) is debated, with an increasing risk of complications from the age of 35, but a threshold of 40 years old is adopted internationally to adjust surveillance and set the term of delivery between 39 and 40 weeks. Patients with AMA have more comorbidities, such as type 2 diabetes and chronic arterial hypertension. They are at greater risk of miscarriage, -gestational diabetes, hypertensive, thrombotic and psychiatric complications, as well as caesarean sections, placenta previa and placental abruption. Additionally, fetal and neonatal complications can occur, including genetic anomalies, fetal growth issues, stillbirths, and prematurity. AMA is a non--modifiable risk factor that must be taken into account to ensure a safe peri-natal period.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"20 891","pages":"1874-1879"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}