{"title":"[Overlooked somatic effects of serotoninergic antidepressants].","authors":"Marie-Anne Pham, Philippe Gonnet, Nicolas Schaad","doi":"10.53738/REVMED.2024.20.885.1540","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.885.1540","url":null,"abstract":"<p><p>The mechanism of action of selective serotonin reuptake inhibitors (SSRI) is still not properly established. It is essential to consider their positive and negative side effects before prescribing. In this article, we describe several of these side effects in the context of common pathologies and clinical situations. We discuss their cardioprotective effect and their role in the functional recovery of patients following stroke. We recall the increase in the risk of bleeding when prescribing SSRI concomitantly with antiaggregating and anticoagulant treatments. Prescribing SSRI also increases the risk of fracture and the frequency of hyponatremia. In the context of COPD, the effects of SSRI are more difficult to establish.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa Polikar, Helena Wegelius, Jean-François Lambert, Jonathan Bloch
{"title":"[Vitamin B9 and B12 : clinical manifestations, screening and substitution].","authors":"Lisa Polikar, Helena Wegelius, Jean-François Lambert, Jonathan Bloch","doi":"10.53738/REVMED.2024.20.885.1544","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.885.1544","url":null,"abstract":"<p><p>Deficiency in vitamins B9 and B12 are common in general practice, due to their high prevalence in the population, especially among elderly patients. This article will present the clinical manifestations of vitamin B9 and B12 deficiencies, which can sometimes be insidious. We will discuss screening strategies, which are based on the presence of compatible symptoms as well as risk factors for deficiency. The choice of administration route for substitution depends both on severity and etiology; but the oral route has demonstrated similar effectiveness compared to intramuscular administration.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aude Molinard-Chenu, Frederic Ehrler, Benno Rehberg, Christian Lovis
{"title":"[Dolodoc: a virtual pain management coach].","authors":"Aude Molinard-Chenu, Frederic Ehrler, Benno Rehberg, Christian Lovis","doi":"10.53738/REVMED.2024.20.885.1568","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.885.1568","url":null,"abstract":"<p><p>Dolodoc is a mobile application aimed at improving autonomy and quality of life for individuals living with chronic pain. Designed as a virtual coach, it offers counseling according to 7 important dimensions of quality of life. Activities, pain and fulfillment of the 7 dimensions of quality of life can be recorded in the application. Moreover, a report can be exported to enhance patient monitoring during clinical interactions. Dolodoc was developed with a user-centered approach and is based on scientific evidence related to the self-management of chronic pain. Indeed, counseling by the coach is based on a multimodal strategy, incorporating elements of physical activity, pacing, positive psychology, and relaxation, among others. Overall, Dolodoc is an innovation that can be used in various clinical settings with an individualized approach.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabelle Da Ernestho Crespin, Sylvain De Lucia, Yves Jackson
{"title":"Santé et environnement. L’engagement des institutions de santé pour des soins durables : exemples genevois et romands.","authors":"Isabelle Da Ernestho Crespin, Sylvain De Lucia, Yves Jackson","doi":"10.53738/REVMED.2024.20.885.1583","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.885.1583","url":null,"abstract":"","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clément Nussbaumer, Antoine Chapot, Mallory Moret Bochatay, Laurent Bochatay
{"title":"[Acute on chronic liver failure: more than just cirrhotic decompensation].","authors":"Clément Nussbaumer, Antoine Chapot, Mallory Moret Bochatay, Laurent Bochatay","doi":"10.53738/REVMED.2024.20.885.1532","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.885.1532","url":null,"abstract":"<p><p>Acute on Chronic Liver Failure (ACLF) is an unfavorable form of cirrhotic disease progression, distinguished from decompensated cirrhosis by a very high short-term mortality associated with damage to one or more organs. The pathophysiology is based on an intense systemic inflammatory reaction, the triggering factor of which can be identified (infection, toxic agent, etc.) in around two thirds of cases. The analogy with sepsis has enabled us to derive prognostic scores linked to organ damage, and thus to better guide these patients, who most often require close monitoring. Treatment remains limited and relies on support for the affected organs. Given the poor prognosis of these patients, attitude discussions should also be part of early management.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antoine Baroz, Yazan Musayeb, Sophie Degrauwe, Marco Roffi, Juan F Iglesias
{"title":"[Vasospastic angina : an underdiagnosed pathology].","authors":"Antoine Baroz, Yazan Musayeb, Sophie Degrauwe, Marco Roffi, Juan F Iglesias","doi":"10.53738/REVMED.2024.20.885.1560","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.885.1560","url":null,"abstract":"<p><p>Vasospastic angina (VSA) was first described in 1959 by Myron Prinzmetal as \"the variant form of angina pectoris\" on the sole basis of medical history and ECG. This condition is currently categorized as an endotype of myocardial infarction without coronary obstruction (Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA)). Diagnostic criteria have been suggested by expert consensus. Provocative testing during coronary angiography is the gold standard test but is rarely used. The clinical presentation is often neglected, and the diagnosis is missed. However, VSA may lead to life-threatening arrhythmias. There are simple and effective therapies that are markedly different from those for the atherosclerotic coronary artery disease.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Deprescribing proton pump inhibitors : what are the clinical practice guidelines ?]","authors":"Liv Mahler, Kenza Bouras, Omar Kherad","doi":"10.53738/REVMED.2024.20.885.1525","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.885.1525","url":null,"abstract":"<p><p>Proton pump inhibitors (PPIs) are frequently overprescribed and maintained without clear indication, leading to significant clinical and economic consequences. Deprescribing, which involves discontinuing or reducing the dose of a medication, lacks clear guidelines for PPIs, despite various approaches being described. Gradual tapering of PPIs appears to be an effective strategy, especially when combined with non-pharmacological measures and multimodal interventions. Additionally, it is crucial to involve the patient in the discussion and ensure a post-tapering follow-up plan.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Médecine de famille : forger les stars de demain par le mentorat.","authors":"Sanae Mazouri","doi":"10.53738/REVMED.2024.20.885.1588","DOIUrl":"https://doi.org/10.53738/REVMED.2024.20.885.1588","url":null,"abstract":"","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}