Robert Rodriguez-Vigouroux, Jörg D Seebach, Geoffrey Urbanski
{"title":"[Inflammatory myopathies in adults. Place of polyvalent immunoglobulins].","authors":"Robert Rodriguez-Vigouroux, Jörg D Seebach, Geoffrey Urbanski","doi":"10.53738/REVMED.2025.21.912.664","DOIUrl":"10.53738/REVMED.2025.21.912.664","url":null,"abstract":"<p><p>Inflammatory myopathies are a heterogeneous group of multi-system autoimmune diseases affecting skeletal muscle. High-dose intravenous immunoglobulins have immunomodulatory properties useful in the treatment of many autoimmune diseases. This review proposes to explore their mechanisms of action and the available evidence concerning their efficacy in inflammatory myopathies. The intravenous immunoglobulins have a good safety profile, but their high cost and limited availability mean that they must be prescribed with caution.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"664-670"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Federal parliamentary debates : complementary medicines and managed care].","authors":"Nelly Sénac, Morgane Jotterand","doi":"10.53738/REVMED.2025.21.912.705","DOIUrl":"10.53738/REVMED.2025.21.912.705","url":null,"abstract":"<p><p>This article looks at the parliamentary debates preceding the popular initiative on complementary medicine (2009) and the referendum on managed-care (2012). A lexicometric analysis of the debates published on the Parliament's website reveals that the theme of federal mandatory insurance law remains central in both cases, while other topics vary depending on the subject. Two distinct logics define the discourse: a partisan positioning logic for complementary medicine and a logic centered on cantonal representation and negotiation for managed care. These findings suggest that the Swiss parliamentary discourse has specific characteristics that warrant further exploration. This study paves the way for analyzing the parliamentary vision of health in Switzerland.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"705-708"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julien Dereme, Maxime Ringwald, Grégoire Stalder, Camillo Ribi
{"title":"[Indolent systemic mastocytosis : an overview in 2025].","authors":"Julien Dereme, Maxime Ringwald, Grégoire Stalder, Camillo Ribi","doi":"10.53738/REVMED.2025.21.912.654","DOIUrl":"10.53738/REVMED.2025.21.912.654","url":null,"abstract":"<p><p>Mast cells (MC) play an important role in the defense against microbial agents, parasites and venoms. The term mastocytosis encompasses a group of diseases characterized by abnormal MC accumulation, divided into cutaneous and systemic forms. The diagnosis of indolent systemic mastocytosis (ISM) is supported by the presence of MC clusters in bone marrow and/or extracutaneous organs, elevated serum tryptase levels, altered expression of MC surface markers, and presence of an activating c-KIT mutation. Patients with ISM carry an increased risk of severe anaphylaxis, particularly to hymenoptera stings. Management of ISM includes symptomatic treatment, avoidance of triggering factors, desensitization and off-label omalizumab. Novel tyrosine kinase inhibitors targeting the mutated c-KIT are promising in refractory ISM and advanced mastocytosis.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"654-659"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Use of democratic tools on health issues in Switzerland].","authors":"Claire-Marie Schertz, Morgane Jotterand","doi":"10.53738/REVMED.2025.21.912.699","DOIUrl":"10.53738/REVMED.2025.21.912.699","url":null,"abstract":"<p><p>The Swiss institutional framework allows for the active participation of citizens in democratic life. However, its modalities deserve to be better known in order to be better mastered, in particular with a view to transmitting a scientific message to the political world. This article focuses on the various democratic tools and the evolution of their use over time on health issues, since the birth of modern Switzerland. It highlights the increase in the number of optional referendums and popular initiatives over the past 35 years on health topics, reflecting the concerns of the population. But for what effects? There are many avenues for reflection that are open.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"699-704"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Faire du neuf avec du vieux.","authors":"Jörg D Seebach","doi":"10.53738/REVMED.2025.21.912.639","DOIUrl":"https://doi.org/10.53738/REVMED.2025.21.912.639","url":null,"abstract":"","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"639-640"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Latest advances in diagnosis and therapy of giant cell arteritis (Horton's disease)].","authors":"Edwin Curraj, Camillo Ribi","doi":"10.53738/REVMED.2025.21.912.648","DOIUrl":"10.53738/REVMED.2025.21.912.648","url":null,"abstract":"<p><p>Giant cell arteritis (GCA, Horton's disease) is a subacute vasculitis of large-size arteries. GCA affects individuals above 50 years and its frequency increases with age. The key elements for diagnosis are clinical presentation, elevated inflammatory markers, imaging, and histology. Temporal artery biopsy is the gold standard for confirming GCA, but is gradually being replaced by non-invasive imaging techniques such as Doppler ultrasound and positron emission tomography. While corticosteroids remain the cornerstone of treatment, new therapies are helping to reduce their dosage and duration of use. In this review, the key aspects of diagnosing and treating GCA, based on the latest recommendations are discussed in this article.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"648-653"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Health Democracy: a national or cantonal issue in Switzerland ?]","authors":"Stéfanie Monod, Laurent Kurth","doi":"10.53738/REVMED.2025.21.912.688","DOIUrl":"10.53738/REVMED.2025.21.912.688","url":null,"abstract":"<p><p>Western health systems are facing unprecedented challenges related to an aging population and climate issues. While the need for care will grow significantly, our societies will have to arbitrate the allocation of both, financial and human resources. Choices will have to be made, making it essential for citizens and patients to participate strongly. In Switzerland, a federal state renowned for its direct democracy, we can ask ourselves at what political level these health democracy issues are situated. Is it primarily the federal or cantonal level? This article discusses, based on the analysis of the distribution of health competences between the Confederation and the canton, the complexity of the governance of the Swiss health system and the opportunities to strengthen this health democracy.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"688-693"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Démocratie sanitaire : des enjeux aussi pour le système de santé suisse.","authors":"Stéfanie Monod, Jacques Cornuz","doi":"10.53738/REVMED.2025.21.912.677","DOIUrl":"https://doi.org/10.53738/REVMED.2025.21.912.677","url":null,"abstract":"","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 912","pages":"677-678"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The mind without images : aphantasia and autism spectrum disorder, an invisible connection.]","authors":"Hedi Klila, Fabienne Giuliani","doi":"10.53738/REVMED.2025.21.911.618","DOIUrl":"https://doi.org/10.53738/REVMED.2025.21.911.618","url":null,"abstract":"<p><p>For people with aphantasia, the ability to form mental images is absent or markedly impaired. In this article, we define aphantasia and explore the links between mental imagery and autism spectrum disorder. Through our clinical experiences, we highlight the repercussions the impact of aphantasia on autism spectrum disorder functioning, share the specific challenges we face in psychotherapy and propose therapeutic approaches.</p>","PeriodicalId":21286,"journal":{"name":"Revue medicale suisse","volume":"21 911","pages":"618-621"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}