Revista da Sociedade Brasileira de Medicina Tropical最新文献_第2页

A rare case report of bezold abscess in a 9-month-old baby. 一个罕见的病例报告bezold脓肿在一个9个月大的婴儿。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0258-2025

Elif Gozgec, Cemile Altinkaya

引用次数: 0

The reversed halo sign in pulmonary paracoccidioidomycosis. 肺副球孢子菌病的反晕征。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0330-2025

Gláucia Zanetti, Elcio Bakowski, Bruno Hochhegger, Edson Marchiori

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Erratum. 勘误表。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-29 DOI: 10.1590/0037-8682-0221B-2023

引用次数: 0

Neurological Complications of Infective Endocarditis. 感染性心内膜炎的神经系统并发症。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0319-2025

Lucas Yunes Cominatto Barbosa, Laisson de Moura Feitoza, Luiza Maretti Scomparin, Lucieni Oliveira Conterno, Fabiano Reis

引用次数: 0

Orbital cellulitis following acute sinusitis in a neonate. 新生儿急性鼻窦炎继发眼眶蜂窝织炎。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0257-2025

Elif Gozgec, Muhammed Mukremin Bugdaci

引用次数: 0

A Rare Case of Primary Musculoskeletal Hydatid Disease Involving the Deltoid Muscle and Humerus. 原发性肌骨骼包虫病累及三角肌及肱骨一例。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0279-2025

M Alperen Kılıç, Hilal Kırmızıgül, Emre Emekli, Murat Tepe

引用次数: 0

A case of tuberculosis in the cavitary lesion suggestive of neoplasm. 提示肿瘤的空腔病灶结核1例。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0229-2025

Cemile Altınkaya, Adem Karaman

引用次数: 0

A Rare Cause of Granulomatous Lymphadenitis: Tularemia. 肉芽肿性淋巴结炎的一种罕见病因：兔热病。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0066-2025

Celal Yazıcı

引用次数: 0

Comprehensive analysis of mutations associated with rifampicin- and isoniazid-resistant tuberculosis in a high-burden setting. 在高负担环境中与利福平和异烟肼耐药结核病相关的突变的综合分析。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-22 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0184-2025

Rosângela Siqueira de Oliveira, Angela Pires Brandão, Fabiane Maria de Almeida Ferreira, Sonia Maria da Costa, Vera Lucia Maria da Silva, Lucilaine Ferrazoli, Erica Chimara, Juliana Maira Watanabe Pinhata

{"title":"Comprehensive analysis of mutations associated with rifampicin- and isoniazid-resistant tuberculosis in a high-burden setting.","authors":"Rosângela Siqueira de Oliveira, Angela Pires Brandão, Fabiane Maria de Almeida Ferreira, Sonia Maria da Costa, Vera Lucia Maria da Silva, Lucilaine Ferrazoli, Erica Chimara, Juliana Maira Watanabe Pinhata","doi":"10.1590/0037-8682-0184-2025","DOIUrl":"10.1590/0037-8682-0184-2025","url":null,"abstract":"Background: In this study, we aimed to describe the mutations associated with first-line drug resistance in Mycobacterium tuberculosis complex (MTBC) isolates from São Paulo, Brazil, between 2019 and 2021.Methods: Mutations in the coding regions of rpoB and katG genes and in the promoter region of the inhA gene in MTBC clinical isolates were detected using the GenoType MTBDRplus assay (LPA). All mutations inferred by LPA were sequenced.Results: Of the 13,489 MTBC isolates with valid LPA results, 657 (4.9%) harbored mutations. The overall prevalence rates of rifampicin-resistant (RIF-R) tuberculosis (TB), isoniazid-resistant (INH-R) TB, and multidrug-resistant (MDR) TB were 1.5, 2.0, and 1.2%, respectively. A significant proportion of RIF-R isolates presented inferred rpoB mutations (89.1%), most of which were the borderline H445N mutation. The inhA promoter C-15T mutation was predominant among the INH-R isolates (52.8%). Most MDR isolates presented rpoB S450L + katG S315T1 mutations. Gene sequencing identified mutations not included in the catalogue of mutations published by the World Health Organization. Phenotypic drug susceptibility testing on isolates with inferred rpoB mutations revealed that the 0.5 µg/mL critical concentration of RIF failed to detect most borderline mutations when using the BACTEC MGIT 960 system.Conclusions: These findings emphasize the need for continuous surveillance and the integration of molecular and phenotypic methods to ensure an accurate detection and management of drug-resistant TB in high-burden settings.","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e01842025"},"PeriodicalIF":2.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prediction of latent tuberculosis infection in Venezuelan immigrants: construction and validation of a surveillance model. 委内瑞拉移民潜伏性肺结核感染的预测：监测模型的构建和验证。

IF 2.3 4区医学

Revista da Sociedade Brasileira de Medicina Tropical Pub Date : 2025-09-22 eCollection Date: 2025-01-01 DOI: 10.1590/0037-8682-0434-2024

Fernanda Zambonin, Nilson Cavalcante de Souza Júnior, Elvira Maria Godinho de Seixas Maciel, José Ueleres Braga

{"title":"Prediction of latent tuberculosis infection in Venezuelan immigrants: construction and validation of a surveillance model.","authors":"Fernanda Zambonin, Nilson Cavalcante de Souza Júnior, Elvira Maria Godinho de Seixas Maciel, José Ueleres Braga","doi":"10.1590/0037-8682-0434-2024","DOIUrl":"10.1590/0037-8682-0434-2024","url":null,"abstract":"Background: Latent tuberculosis infection (LTBI) is a significant concern among migrant populations, particularly Venezuelans, due to its adverse health and social conditions. This study aimed to construct and validate a predictive model of LTBI among Venezuelan migrants.Methods: This cross-sectional study utilized data from the project \"TB and migrants in BRICS countries: The case of Brazil\", carried out in Boa Vista, Roraima, in 2020. The final sample included 427 participants. For the analysis, 22 variables were selected, and simple and multiple logistic regression analyses were applied. General measures (Nagalkerke's R2 and Brier's score), discriminative capacity (accuracy, receiver operating characteristic curve, and area under the curve [AUC]), and calibration measures (Hosmer-Lemeshow test and calibration graph) were used to evaluate the model. The model was internally validated using bootstrapping. Finally, a nomogram and a clinical decision curve were constructed.Results: Six LTBI predictors (marital status, social benefit, documentation status, smoking status, presence of comorbidities, and fever) were included in the final model. The predictive model demonstrated moderate discriminatory capacity (AUC: 0.676), good calibration, and was also validated with an AUC of 0.678. Additionally, a clinical decision analysis revealed that the use of the model offers superior benefits compared with traditional treatment strategies.Conclusions: The predictive model and nomogram proved to be useful tools for LTBI screening in migrants, potentially guiding border health surveillance actions in this population.","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"58 ","pages":"e04342024"},"PeriodicalIF":2.3,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12455750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0