Antonio Edvan Camelo-Filho, Pedro Lucas Grangeiro de Sá Barreto Lima, Francisco Luciano Honório Barreto Cavalcante, Pedro Vitor Ferreira Rodrigues, Oliver Reiks Miyajima, Pedro Braga-Neto, Paulo Ribeiro Nóbrega
{"title":"Multiple Mononeuropathy following Crotalid Envenomation: A case report.","authors":"Antonio Edvan Camelo-Filho, Pedro Lucas Grangeiro de Sá Barreto Lima, Francisco Luciano Honório Barreto Cavalcante, Pedro Vitor Ferreira Rodrigues, Oliver Reiks Miyajima, Pedro Braga-Neto, Paulo Ribeiro Nóbrega","doi":"10.1590/0037-8682-0273-2024","DOIUrl":"10.1590/0037-8682-0273-2024","url":null,"abstract":"<p><p>A 34-year-old man developed severe envenomation after being bitten by a Crotalus durissus (rattlesnake), which was treated with anticrotalic serum. Three weeks later, the patient reported paresthesia and neuropathic pain in the left hand, which had progressed to all four limbs. Electroneuromyography revealed asymmetric axonal sensorimotor multiple mononeuropathy. The patient was treated with prednisone, and six months later there was significant improvement in sensorimotor conduction. This is the first reported case of multiple mononeuropathy associated with C. durissus envenomation. Post-snake envenomation peripheral neuropathy is a rare complication requiring prompt recognition and treatment to optimize nerve function and enhance patient outcomes.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e008082024"},"PeriodicalIF":1.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum.","authors":"","doi":"10.1590/0037-8682-0190B-2024","DOIUrl":"10.1590/0037-8682-0190B-2024","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/0037-8682-0190-2024].</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e019002024"},"PeriodicalIF":1.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Hiroshi Minagawa, Ettore Rafael Mai Almeida, Rafaela Caroline de Souza, Daniela Carvalho Dos Santos, Vidal Haddad Junior, Hélio Amante Miot
{"title":"Gamasoidosis (avian mite dermatitis) outbreak in a student dormitory.","authors":"Fernando Hiroshi Minagawa, Ettore Rafael Mai Almeida, Rafaela Caroline de Souza, Daniela Carvalho Dos Santos, Vidal Haddad Junior, Hélio Amante Miot","doi":"10.1590/0037-8682-0228-2024","DOIUrl":"10.1590/0037-8682-0228-2024","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e011012024"},"PeriodicalIF":1.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Fantinatti, Eduardo José Lopes Torres, Alda Maria Da-Cruz
{"title":"Enterobiasis: A Neglected or Forgotten Disease?","authors":"Maria Fantinatti, Eduardo José Lopes Torres, Alda Maria Da-Cruz","doi":"10.1590/0037-8682-0323-2024","DOIUrl":"10.1590/0037-8682-0323-2024","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e012002024"},"PeriodicalIF":1.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bruno Fonseca Martins da Costa Andrade, Luzia Helena Queiroz, Márcia Marinho
{"title":"Human anti-rabies care in the State of São Paulo: evaluating prophylaxis conduct in individuals attacked by dogs and cats.","authors":"Bruno Fonseca Martins da Costa Andrade, Luzia Helena Queiroz, Márcia Marinho","doi":"10.1590/0037-8682-0170-2023","DOIUrl":"10.1590/0037-8682-0170-2023","url":null,"abstract":"<p><strong>Background: </strong>Rabies is a zoonosis usually transmitted to mammals via contact between the saliva of infected animals and either the skin or mucosa of the attacked individual, and post-exposure prophylaxis (PEP) is the only way to avoid the disease. This study aimed to perform a descriptive analysis of PEP after attacks by dogs and cats in the state of São Paulo.</p><p><strong>Methods: </strong>We analyzed the disease compulsory notification forms Human Anti-Rabies Care (CID10: W64), available in the Notifiable Diseases Information System (SINAN), from 2013 to 2017. Treatment adequacy was analyzed according to the parameters established by the Brazilian Health Ministry.</p><p><strong>Results: </strong>A total of 572,889 notifications were reported during the study period, 94.1% (538,975) of which corresponded to dog or cat attacks, with an occurrence of 26.9 cases per 10,000 inhabitants. Among the recommended procedures, the most frequent was the observation of the animals for 10 days (44.4%), which was adopted inappropriately at a lower frequency. Prophylactic conduct was adequate in 68.8% of the cases, but only 55.5% of the individuals received adequate treatment. More than 112 thousand individuals (31,4%) received a correct recommendation for PEP but did not receive adequate treatment, leading to 246,787 doses of the vaccine and 8,888 doses of rabies immunoglobulin administered without following the recommendations of the Ministry of Health.</p><p><strong>Conclusions: </strong>The use of immunobiologicals is excessive, indicating the need for investment in training health professionals to follow the recommendations of the Ministry of Health.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e004202024"},"PeriodicalIF":1.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristiane Medeiros Moraes de Carvalho, Gilmar Ribeiro-Jr, Rodrigo Gurgel-Gonçalves, Liane Santiago Andrade, Cicílio Alves Moraes, Maria Aparecida Araújo Figueiredo
{"title":"Spatio-temporal trends in mortality due to Chagas disease in the State of Bahia, Brazil, from 2008 to 2018.","authors":"Cristiane Medeiros Moraes de Carvalho, Gilmar Ribeiro-Jr, Rodrigo Gurgel-Gonçalves, Liane Santiago Andrade, Cicílio Alves Moraes, Maria Aparecida Araújo Figueiredo","doi":"10.1590/0037-8682-0058-2024","DOIUrl":"10.1590/0037-8682-0058-2024","url":null,"abstract":"<p><strong>Background: </strong>Chagas disease is a silent illness with high mortality burden in many Latin American countries, such as Brazil. Bahia has the fourth highest mortality rate in Brazil. This study analyzed the temporal trends and regional differences in the mortality rate of Chagas disease in Bahia State from 2008 to 2018.</p><p><strong>Methods: </strong>A time-series analysis of Chagas disease-related deaths was conducted using data from the Mortality Information System of Brazil. We compared the mortality rate due to Chagas disease as the primary cause and mention of the disease in the death certificate, standardized by age and health macroregion/residence municipality, and mapped hot and coldspots.</p><p><strong>Results: </strong>The Chagas Disease Mortality Rate in Bahia during the study period revealed a stationary trend, ranging from 5.34 (2008) to 5.33 (2018) deaths per 100,000 inhabitants. However, the four health macroregions showed an upward trend in mortality rates. The mortality rate (age-adjusted) ranged from 4.3 to 5.1 deaths per 100,000 inhabitants between 2008 and 2018. We observed a upward trend in the mortality rate among individuals aged ≥70 years and a higher incidence of death among men than among women. Of the total number of deaths (8,834), 79.3% had Chagas disease as the primary cause and the death certificates of 20.7% mentioned the disease. Cardiac complications were reported in 85.1% of the deaths due to Chagas disease.</p><p><strong>Conclusions: </strong>The regional and individual differences in the mortality rate of Chagas disease highlighted in this study may support health planning that considers the peculiarities of the territory.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e004172024"},"PeriodicalIF":1.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rodrigo Gurgel-Gonçalves, Wanderson Kleber de Oliveira, Julio Croda
{"title":"The greatest Dengue epidemic in Brazil: Surveillance, Prevention, and Control.","authors":"Rodrigo Gurgel-Gonçalves, Wanderson Kleber de Oliveira, Julio Croda","doi":"10.1590/0037-8682-0113-2024","DOIUrl":"https://doi.org/10.1590/0037-8682-0113-2024","url":null,"abstract":"<p><p>In this review, we discuss dengue surveillance, prevention, and control measures in Brazil. Data on dengue epidemics between 2000 and 2024 indicates an increase in the number of dengue cases and deaths. Global climate change is a key driver of this growth. Over the past 25 years, nearly 18 million Brazilians have been infected with the dengue virus, and the highest number of dengue cases in Brazil's history is projected to reach 2024. Dengue mortality in Brazil increased geographically over time. As of June, there were approximately 6 million probable cases and 4,000 confirmed deaths in Brazil, which represents the greatest dengue epidemic to date. Several technologies have been developed to control Aedes aegypti, including the deployment of Wolbachia-infected mosquitoes, indoor residual spraying, sterile insect techniques, and mosquito-disseminated insecticides. The Ministry of Health recommends integrating these technologies into health services. Brazil is the first country to incorporate the Takeda vaccine into its public health system, and the Butantan vaccine is currently undergoing Phase 3 clinical trials. Increasing the vaccination coverage and implementing novel Ae. aegypti control technologies could reduce the number of dengue cases in Brazil in the coming years. Community activities such as home cleaning and elimination of potential mosquito breeding sites, facilitated by social media and health education initiatives, must continue to achieve this reduction. Ultimately, a multisectoral approach encompassing sanitary improvements, mosquito control, vaccination, and community mobilization is crucial in the fight against dengue epidemics.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e002032024"},"PeriodicalIF":1.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marla de Oliveira D'Esquivel, Vanessa Paulino da Cruz Veira, Daniel Moreira de Avelar, Érika Monteiro Michalsky, Nathália Cristina Lima Pereira, Consuelo Latorre Fortes-Dias, Edelberto Santos Dias
{"title":"Presence of Leishmania sp. amastigotes in the reproductive tract of dogs with visceral leishmaniasis.","authors":"Marla de Oliveira D'Esquivel, Vanessa Paulino da Cruz Veira, Daniel Moreira de Avelar, Érika Monteiro Michalsky, Nathália Cristina Lima Pereira, Consuelo Latorre Fortes-Dias, Edelberto Santos Dias","doi":"10.1590/0037-8682-0237-2023","DOIUrl":"https://doi.org/10.1590/0037-8682-0237-2023","url":null,"abstract":"<p><strong>Background: </strong>Although canine visceral leishmaniasis (CVL) transmission primarily occurs through the bite of phlebotomine sand flies infected with Leishmania infantum, alternative routes may exist.</p><p><strong>Methods: </strong>Thirty-four dogs diagnosed with CVL were sampled for parasitological investigation in tissues from the reproductive tract.</p><p><strong>Results: </strong>Amastigotes of Leishmania sp. were present in 79% (27/34) of the reproductive system samples, with distinct infection rates depending on the tissue.</p><p><strong>Conclusions: </strong>Our data confirms that alternative routes, such as horizontal and vertical transmissions, should be considered in the epidemiological chain of CVL.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e007122024"},"PeriodicalIF":1.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142352956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lia Gonçalves Possuelo, Karine Zenatti Ely, Milena Mantelli Dall Soto, Eduarda Gassen Boeira, Samantha Lopes de Moraes Longo, Pauline Schwarzbold, Tiago Antônio Heringer, Ricardo Alexandre Arcênio, Julio Henrique da Rosa Croda, Andreia Rosane de Moura Valim
{"title":"Health Care for the Population Deprived of Liberty: Overcoming Challenges and Promoting Citizenship.","authors":"Lia Gonçalves Possuelo, Karine Zenatti Ely, Milena Mantelli Dall Soto, Eduarda Gassen Boeira, Samantha Lopes de Moraes Longo, Pauline Schwarzbold, Tiago Antônio Heringer, Ricardo Alexandre Arcênio, Julio Henrique da Rosa Croda, Andreia Rosane de Moura Valim","doi":"10.1590/0037-8682-0190-2024","DOIUrl":"10.1590/0037-8682-0190-2024","url":null,"abstract":"","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e006042024"},"PeriodicalIF":1.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thiago da Silva Santos Malaquias, Eunice Petris Ribeiro, Tatiana Cristina Pereira Dutra, Marina Ricardo, Richard Salvato, Marcela Bhering, Daniella Castanheira Bartholomeu, Elis Regina Dalla-Costa, Miguel Viveiros, Elisangela Costa da Silva, Afrânio Kritski
{"title":"The performance of Xpert MTB/RIF and MTBDRplus within a Programmatic setting at TB Laboratory in Rio de Janeiro, Brazil.","authors":"Thiago da Silva Santos Malaquias, Eunice Petris Ribeiro, Tatiana Cristina Pereira Dutra, Marina Ricardo, Richard Salvato, Marcela Bhering, Daniella Castanheira Bartholomeu, Elis Regina Dalla-Costa, Miguel Viveiros, Elisangela Costa da Silva, Afrânio Kritski","doi":"10.1590/0037-8682-0167-2024","DOIUrl":"10.1590/0037-8682-0167-2024","url":null,"abstract":"<p><strong>Background: </strong>Few studies in routine settings have confirmed the high accuracy of the Xpert MTB/RIF assay for detecting rifampicin resistance (RR) and the first-line probe assay (FL-LPA) for detecting both RR and isoniazid resistance (INHR).</p><p><strong>Methods: </strong>The performance of Xpert MTB/RIF and MTBDRplus VER 2.0 LPA was evaluated in 180 Mycobacterium tuberculosis samples collected from January 2018 to December 2019 in Rio de Janeiro, Brazil. The results were compared with those from BACTEC MGIT 960 culture and drug susceptibility testing (DST). Whole-genome sequencing was performed on the samples with discordant results.</p><p><strong>Results: </strong>The Xpert MTB/RIF assay showed a sensitivity (Se) of 93.3% and a specificity (Sp) of 97.6%, detecting RR. The performance of FL-LPA to identify RIF and INH resistance was, respectively, (Se) 100% and 83.3% and (Sp) 98.8% and 100%. Among 18 clinical isolates with INHR detected by FL-LPA, mutations in the katG gene were observed in 100% of samples, of which only two (11.1%) had mutations in both katG and inhA genes. Overall, the discordant results were identified in 9 (5%) samples. Among the four Xpert RIF-resistant and DST-sensitive, two harbored mutations in rpoB Leu430Pro. Among the four FL-LPA-sensitive and DST-resistant, one had a mutation in inhA 17G>T. FL-LPA showed high accuracy in detecting RR and INHR.</p><p><strong>Conclusions: </strong>The MTBDRplus test demonstrated excellent performance in detecting RR, and INHR in clinical isolates under routine conditions at a reference laboratory in Rio de Janeiro, Brazil. Incorporating both tests can improve drug-resistant tuberculosis treatment outcomes and monitor the INHR incidence.</p>","PeriodicalId":21199,"journal":{"name":"Revista da Sociedade Brasileira de Medicina Tropical","volume":"57 ","pages":"e004162024"},"PeriodicalIF":1.8,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}