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Fetal and neonatal alloimmune thrombocytopenia. 胎儿和新生儿同种免疫性血小板减少症。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
J P Espinoza, J Caradeux, Errol R Norwitz, S E Illanes
{"title":"Fetal and neonatal alloimmune thrombocytopenia.","authors":"J P Espinoza,&nbsp;J Caradeux,&nbsp;Errol R Norwitz,&nbsp;S E Illanes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fetomaternal alloimmune thrombocytopenia (FMAIT) is a relatively uncommon disease, but is the leading cause of severe thrombocytopenia in the newborn. It can cause severe complications and long-term disabilities. The main objective of screening is to reduce both the morbidity and mortality associated with FMAIT, primarily by preventing intracranial hemorrhage. However, controversy surrounds both pre- and antenatal management. This article discusses pathogenesis, screening, diagnosis, and both pre- and neonatal management of FMAIT.</p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 1","pages":"e15-21"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651544/pdf/RIOG006001_0e15.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31441720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between maternal periodontal status and preterm low birth weight. 母亲牙周状况与早产儿低出生体重的关系。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
Mansi Bansal, Manish Khatri, Ashish Kumar, Gouri Bhatia
{"title":"Relationship between maternal periodontal status and preterm low birth weight.","authors":"Mansi Bansal,&nbsp;Manish Khatri,&nbsp;Ashish Kumar,&nbsp;Gouri Bhatia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Throughout history, there has been the belief that diseases that affect the mouth, such as periodontal disease, can have an effect on the rest of the body. It is only very recently that scientists and clinicians have begun to provide an increasing body of scientific evidence suggesting that moderate untreated periodontitis may affect an individual systemically, and may contribute to cardiovascular disease, diabetes, and preterm low birth weight. Birth weight is affected by multiple factors and is considered as an outcome of a complex multifactorial system. Periodontitis is a remote gram-negative infection that may play a role in low birth weight. Periodontopathic microorganisms and their products have a wide range of effects mediated through host cytokine production in target cells. Many combined animal studies and data supporting plausible biologic mechanisms suggest that periodontal infection has a negative impact on pregnancy outcome in some women. </p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 3-4","pages":"135-40"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002189/pdf/RIOG006003_0135.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32339356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
One and the same. 是一样的。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
Ryan T Fitzgerald
{"title":"One and the same.","authors":"Ryan T Fitzgerald","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 3-4","pages":"105-6"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002185/pdf/RIOG006003_0105.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32416416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern Risk Assessment for Individualizing Treatment Concepts in Early-stage Breast Cancer. 早期乳腺癌个体化治疗理念的现代风险评估。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
Alex Farr, Rachel Wuerstlein, Annika Heiduschka, Christian F Singer, Nadia Harbeck
{"title":"Modern Risk Assessment for Individualizing Treatment Concepts in Early-stage Breast Cancer.","authors":"Alex Farr,&nbsp;Rachel Wuerstlein,&nbsp;Annika Heiduschka,&nbsp;Christian F Singer,&nbsp;Nadia Harbeck","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Validated prognostic and predictive factors currently play an important role in treatment planning for patients with early-stage breast cancer. The role of personalized medicine has led to the search for markers that can be applied to individual patients to optimize treatment regimens. In addition to traditional clinicopathologic measures, scores and gene tests have been developed to independently predict risk of patients in the neoadjuvant and adjuvant settings. The discovery of these markers provides the opportunity to identify patients at such low risk of recurrence that toxic therapy side effects are not justified. Selection and management of patients with early-stage, hormone receptor-positive breast cancer who are appropriately treated with endocrine therapy alone after receiving locoregional therapy but do not necessarily require adjuvant chemotherapy is currently problematic. This article reviews the current state-of-theart biomarker assessment methods and discusses the potential role for the prediction of chemotherapy benefit focusing on endocrine sensitive disease. </p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 3-4","pages":"165-73"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002193/pdf/RIOG006003_0165.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32416419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal screening for fragile x: carriers, controversies, and counseling. 脆性 X 的产前筛查：携带者、争议和咨询。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
Julie F Gutiérrez, Komal Bajaj, Susan D Klugman
{"title":"Prenatal screening for fragile x: carriers, controversies, and counseling.","authors":"Julie F Gutiérrez, Komal Bajaj, Susan D Klugman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In addition to causing developmental disability in future offspring, fragile X carrier status has important reproductive and mental health implications for the individual being tested. Accordingly, prenatal carrier screening and diagnosis using DNA-based molecular methods has become crucial in early detection, intervention, and family planning. Although the list of known genetic disorders is growing daily, controversy remains over who should be tested for fragile X. FMR1 gene mutations can result in inherited intellectual disability, infertility, and neurodegeneration syndromes that are encountered by clinicians in a variety of settings. Patients and clinicians are still largely unfamiliar with this disorder, its complicated inheritance, and its heterogeneous phenotype. Debate continues over who should be offered prenatal carrier screening. As more disease screening is offered, pretest counseling will become only more complex and clinicians will further struggle to balance the needs of the individual and allocation of public health resources.</p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 1","pages":"e1-7"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651542/pdf/RIOG006001_00e1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31441719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuberculosis and the obstetrician-gynecologist: a global perspective. 结核病与妇产科医生：全球视角。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
Rose L Molina, Khady Diouf, Nawal M Nour
{"title":"Tuberculosis and the obstetrician-gynecologist: a global perspective.","authors":"Rose L Molina, Khady Diouf, Nawal M Nour","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tuberculosis (TB) infection poses substantial challenges for obstetricians and gynecologists globally, as gynecologic involvement may cause infertility, irregular bleeding, and pelvic pain. If TB-infected women are able to conceive, obstetric complications include intrauterine growth restriction and, more rarely, congenital transmission. Appropriate screening for high-risk populations is crucial for diagnosis and treatment of latent and active TB infection, which may prevent reproductive sequelae for individual patients and, eventually, contribute to complete eradication of the disease. </p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 3-4","pages":"174-81"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002194/pdf/RIOG006003_0174.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32340349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amniocentesis for fetal lung maturity: will it become obsolete? 羊膜穿刺术检测胎儿肺成熟度:会过时吗?
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
Stephen Varner, Craig Sherman, David Lewis, Sheri Owens, Frankie Bodie, C Eric McCathran, Nicolette Holliday
{"title":"Amniocentesis for fetal lung maturity: will it become obsolete?","authors":"Stephen Varner,&nbsp;Craig Sherman,&nbsp;David Lewis,&nbsp;Sheri Owens,&nbsp;Frankie Bodie,&nbsp;C Eric McCathran,&nbsp;Nicolette Holliday","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>AMNIOCENTESIS FOR FETAL LUNG MATURITY HAS HISTORICALLY BEEN PERFORMED FOR MANY REASONS: uterine and placental complications, maternal comorbidities, fetal issues, and even obstetric problems. Even though the risks associated with third trimester amniocentesis are extremely low, complications have been documented, including preterm labor, placental abruptions, intrauterine rupture, maternal sepsis, fetal heart rate abnormalities, and fetal-maternal hemorrhage. This review presents the types of tests for fetal lung maturity, presents the indications and tests utilized, and discusses recommendations for when amniocentesis for fetal lung maturity may be appropriate. </p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 3-4","pages":"126-34"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002188/pdf/RIOG006003_0126.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32339355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fetal and neonatal alloimmune thrombocytopenia. 胎儿和新生儿同种免疫性血小板减少症。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01 DOI: 10.3909/RIOG0202
J. P. Espinoza, J. Caradeux, E. Norwitz, S. Illanes
{"title":"Fetal and neonatal alloimmune thrombocytopenia.","authors":"J. P. Espinoza, J. Caradeux, E. Norwitz, S. Illanes","doi":"10.3909/RIOG0202","DOIUrl":"https://doi.org/10.3909/RIOG0202","url":null,"abstract":"Fetomaternal alloimmune thrombocytopenia (FMAIT) is a relatively uncommon disease, but is the leading cause of severe thrombocytopenia in the newborn. It can cause severe complications and long-term disabilities. The main objective of screening is to reduce both the morbidity and mortality associated with FMAIT, primarily by preventing intracranial hemorrhage. However, controversy surrounds both pre- and antenatal management. This article discusses pathogenesis, screening, diagnosis, and both pre- and neonatal management of FMAIT.","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"31 1","pages":"e15-21"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81337523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Barbed suture: a review of the technology and clinical uses in obstetrics and gynecology. 带刺缝合：妇产科技术和临床应用综述。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
James A Greenberg, Randi H Goldman
{"title":"Barbed suture: a review of the technology and clinical uses in obstetrics and gynecology.","authors":"James A Greenberg, Randi H Goldman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Surgical knots are simply a necessary evil needed to anchor smooth suture to allow it to function in its role in tissue reapproximation. Surgical knots reduce the tensile strength of all sutures by thinning and stretching the material. The tying of surgical knots introduces the potential of human error and interuser variability. Knot-secured smooth suture must create an uneven distribution of tension across the wound with the higher tension burdens placed at the knots. Given the excessive relative wound tension on the knot and the reasonable concerns of surgeons for suture failure due to knot slippage, there is a natural tendency toward overcoming these concerns by over-tightening knots; however, tighter knots may be worse for wound healing and strength than looser knots. In minimally invasive laparoscopic surgeries, the ability to quickly and properly tie surgical knots presents a new challenge. In cases in which knot tying is difficult, the use of knotless barbed suture can securely reapproximate tissues with less time, cost, and aggravation. This article reviews the technology behind barbed sutures with a focus on understanding how they differ from traditional smooth sutures and how barbed sutures have performed in in vitro and animal model testing, as well as in human clinical trials. </p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 3-4","pages":"107-15"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002186/pdf/RIOG006003_0107.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32416417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of thrombolytic agents to treat pulmonary embolism in pregnancy. 使用溶栓剂治疗妊娠期肺栓塞。
Reviews in obstetrics & gynecology Pub Date : 2013-01-01
Mohammad Yusuf Beebeejaun, Olumayowa Adenugba
{"title":"Use of thrombolytic agents to treat pulmonary embolism in pregnancy.","authors":"Mohammad Yusuf Beebeejaun,&nbsp;Olumayowa Adenugba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pulmonary embolism in pregnancy is a major cause of maternal mortality and morbidity. We describe the case of a 27-year-old pregnant woman who underwent successful thrombolysis. Our patient presented to the emergency department after a fainting episode and complaining of shortness of breath. A computed tomography pulmonary angiogram revealed a pulmonary embolism, which was found to be causing significant right ventricular strain. After examination by our gynecologic and medical teams, she underwent successful thrombolysis, made a successful recovery, and carried an uneventful pregnancy. </p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"6 3-4","pages":"182-4"},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002195/pdf/RIOG006003_0182.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32418490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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