Reproductive biomedicine online最新文献_第2页

Inside Front Cover - Affiliations and First page of TOC 封面内页 - 隶属机构和目录首页

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-09-12 DOI: 10.1016/S1472-6483(24)00606-0

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Would surgical retrieval of product of conception for the purpose of genetic analysis increase the risk of intrauterine adhesions? 为进行基因分析而手术取出受孕产物是否会增加宫内粘连的风险？

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-09-11 DOI: 10.1016/j.rbmo.2024.104445

Lionel Reyftmann

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Association of Vitamin D receptor gene polymorphisms (FokI, ApaI, TaqI), metabolic features and susceptibility to polycystic ovary syndrome: a preliminary single center case-control study 维生素 D 受体基因多态性（FokI、ApaI、TaqI）、代谢特征与多囊卵巢综合征易感性的关系：一项初步的单中心病例对照研究

IF 4 2区医学

Reproductive biomedicine online Pub Date : 2024-09-08 DOI: 10.1016/j.rbmo.2024.104447

Talida Vulcan, Iancu Mihaela, Lucia Maria Procopciuc, Tudor Sergiu Suciu, Gabriela Adriana Filip

{"title":"Association of Vitamin D receptor gene polymorphisms (FokI, ApaI, TaqI), metabolic features and susceptibility to polycystic ovary syndrome: a preliminary single center case-control study","authors":"Talida Vulcan, Iancu Mihaela, Lucia Maria Procopciuc, Tudor Sergiu Suciu, Gabriela Adriana Filip","doi":"10.1016/j.rbmo.2024.104447","DOIUrl":"https://doi.org/10.1016/j.rbmo.2024.104447","url":null,"abstract":"Are the combined genotypes and haplotypes of VDR gene polymorphisms () associated with PCOS susceptibility and metabolic features of the disease? We performed a case-control study, including 46 women with PCOS and 48 controls. Genotypes of VDR genes were determined using the PCR-RFLP (restriction fragment length polymorphism) method. In all women, the waist circumference, parameters of lipid and glucose metabolism were evaluated. PCOS group presented higher waist circumference and visceral adiposity index (VAI) levels compared to controls. Total cholesterol, LDL-C and triglycerides had higher values in PCOS women. VDR- C/C (F/F) genotype had significantly higher odds of PCOS (adjusted OR = 6.27, 95% CI: 1.53-25.65). VDR- was associated with susceptibility to PCOS in the dominant model, the variant genotype (A/C-A/A) (A/a- a/a) had higher odds of PCOS than the wild genotype C/C (A/A) (adjusted OR = 3.15, 95% CI: 1.07-9.32). Haplotype analysis revealed that T-C- T (f-A-T) haplotype was statistically associated with lower odds of PCOS (adjusted OR = 0.10, 95% CI: 0.01-0.95). PCOS women with VDR-Fokl T/T (f/f) genotype had lower fasting glucose and higher VAI levels compared to C/T (Ff) or C/C (F/F) genotype. The present findings suggest the association between and polymorphisms and PCOS susceptibility. Moreover, T/T (f/f) genotype of VDR- could be a marker of decreased fasting glucose in PCOS. polymorphism did not reveal a relationship with PCOS susceptibility in our study population.","PeriodicalId":21134,"journal":{"name":"Reproductive biomedicine online","volume":null,"pages":null},"PeriodicalIF":4.0,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142256872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Donor sperm: only for the rich and straight. 捐献精子：只适合有钱人和正直的人。

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-09-03 DOI: 10.1016/j.rbmo.2024.104434

Guido Pennings

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Polar body-based PGT-A: not dead yet? A step forward back to the roots of PGT-A. 基于极地车身的 PGT-A：尚未消亡？回到 PGT-A 的根源，向前迈出一步。

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-08-30 DOI: 10.1016/j.rbmo.2024.104430

Anna Oberle, Michael Feichtinger

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Inside Front Cover - Affiliations and First page of TOC 封面内页 - 隶属机构和目录首页

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-08-22 DOI: 10.1016/j.rbmo.2024.104387

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Outside Back Cover - Editorial Board 封底外页 - 编辑委员会

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-08-22 DOI: 10.1016/j.rbmo.2024.104390

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Front Matter - Continued TOC 前言 - 续目录

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-08-22 DOI: 10.1016/j.rbmo.2024.104388

引用次数: 0

Effect of adenomyosis on placenta-related obstetric complications. 子宫腺肌症对胎盘相关产科并发症的影响。

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-08-21 DOI: 10.1016/j.rbmo.2024.104414

Ran Matot, Uval Bar-Peled, Yossi Geron, Shir Danieli-Gruber, Yinon Gilboa, Lior Drukker, Haim Krissi, Adi Borovich, Sharon Perlman

{"title":"Effect of adenomyosis on placenta-related obstetric complications.","authors":"Ran Matot, Uval Bar-Peled, Yossi Geron, Shir Danieli-Gruber, Yinon Gilboa, Lior Drukker, Haim Krissi, Adi Borovich, Sharon Perlman","doi":"10.1016/j.rbmo.2024.104414","DOIUrl":"https://doi.org/10.1016/j.rbmo.2024.104414","url":null,"abstract":"<p><strong>Research question: </strong>What is the relationship between sonographic diagnosis of isolated adenomyosis and placenta-associated obstetric outcomes?</p><p><strong>Design: </strong>In this 12-year retrospective cohort study (2010-2022), patients presenting with adenomyosis-related symptoms were assessed via ultrasound. The study included 59 women diagnosed with adenomyosis and 62 controls, leading to 203 births (90 in the adenomyosis group and 113 in the control group). Patients with endometriosis, uterine fibroids and anomalies, and those using assisted reproductive technology were excluded. The primary outcome focused on a composite of placenta-associated adverse outcomes, including preterm birth, small-for-gestational-age fetuses, hypertensive disorders of pregnancy, placental abruption and post-partum haemorrhage.</p><p><strong>Results: </strong>No clinically significant differences in demographic characteristics were noted between the two groups. However, the adenomyosis group showed a significantly higher rate of adverse placental function outcomes (27%) compared with the control group (11%, P = 0.005). Adjusted analyses for maternal age, parity and aspirin usage revealed increased risk of hypertensive disorders (adjusted OR 5.91, 95% CI 1.50-30.0; P = 0.017) and adverse placental function outcomes (adjusted OR 3.44, 95% CI 1.53-8.09; P = 0.003) in the adenomyosis group.</p><p><strong>Conclusion: </strong>Adenomyosis is significantly associated with increased risk of adverse placental function outcomes and hypertensive disorders of pregnancy. These findings suggest that adenomyosis may have a distinct impact on pregnancy, underscoring the need for further research to elucidate specific sonographic characteristics of adenomyosis and their effects on placental function.</p>","PeriodicalId":21134,"journal":{"name":"Reproductive biomedicine online","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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A prospective study examining the value of three-dimensional transvaginal ultrasonography during the diagnosis and evaluation of Asherman syndrome 一项前瞻性研究，探讨经阴道三维超声波检查在诊断和评估阿什曼综合征中的价值。

IF 3.7 2区医学

Reproductive biomedicine online Pub Date : 2024-08-21 DOI: 10.1016/j.rbmo.2024.104404

Rui Huang , Sijing Li , Yuting Zhao , YingTao Li , Mingyang Ge , Sotirios Saravelos , Xiaodan Lv , Qi Cheng , Xiaowu Huang , Enlan Xia , Tin-Chiu Li

{"title":"A prospective study examining the value of three-dimensional transvaginal ultrasonography during the diagnosis and evaluation of Asherman syndrome","authors":"Rui Huang , Sijing Li , Yuting Zhao , YingTao Li , Mingyang Ge , Sotirios Saravelos , Xiaodan Lv , Qi Cheng , Xiaowu Huang , Enlan Xia , Tin-Chiu Li","doi":"10.1016/j.rbmo.2024.104404","DOIUrl":"10.1016/j.rbmo.2024.104404","url":null,"abstract":"<div><h3>Research question</h3><div>What is the value of three-dimensional (3D) transvaginal ultrasonography (TVS) in the diagnosis and assessment of Asherman syndrome?</div></div><div><h3>Design</h3><div>This was a prospective study conducted at a hysteroscopy centre.</div></div><div><h3>Results</h3><div>A total of 685 participants were recruited, 65 dropped out and 620 were finally enrolled and analysed. The overall sensitivity, specificity and accuracy of 3D-TVS in the diagnosis of Asherman syndrome were 95.7%, 80.7% and 93.5%, respectively, and the sensitivity and accuracy were significantly higher than those of two-dimensional (2D) TVS (<em>P</em> < 0.001). The likelihood of 2D-TVS missing a case of mild intrauterine adhesions (IUA) was 43.7%, compared with only 6.2% for 3D-TVS. The frequency of involvement of each anatomical area by adhesions in decreasing order was right and left uterine side walls (both 80%), central or mid-cavity (31%), right cornual region (26%), left cornual region (23%), fundal wall (15%) and isthmus (4.5%). The correlation between 3D-TVS and hysteroscopy in each of the seven anatomical areas was analysed separately. The results showed good agreement with regard to the three uterine walls (fundus, left lateral and right lateral), with kappa values of 0.678–0.811. The likelihood of the IUA being severe in nature when there were five or more areas, three or four areas, or one or two areas was 82%, 37.1% and 6.3%, respectively (<em>P</em> < 0.001).</div></div><div><h3>Conclusions</h3><div>The diagnostic value of 3D-TVS is higher than that of 2D-TVS. In clinical practice, 3D-TVS should whenever possible replace 2D-TVS as the initial method of assessment to decide if hysteroscopy is necessary and to help with planning surgery.</div></div>","PeriodicalId":21134,"journal":{"name":"Reproductive biomedicine online","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142506937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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