Recent patents on biotechnology最新文献_第9页

WITHDRAWN: Scrutinizing the Role of Genetically ModifiedHerbs (GMHs) in the Treatment of Various Diseases 撤回：研究转基因草药在治疗各种疾病方面的作用

Recent patents on biotechnology Pub Date : 2022-05-12 DOI: 10.2174/1872208316666220512113921

Rakesh K Sindhu, Rishu Verma, Twinkle Salgotra, Piyush Madaan, Parteek Chandel, Gaber El-Saber Batiha, Simona Cavalu

{"title":"WITHDRAWN: Scrutinizing the Role of Genetically Modified\u0000Herbs (GMHs) in the Treatment of Various Diseases","authors":"Rakesh K Sindhu, Rishu Verma, Twinkle Salgotra, Piyush Madaan, Parteek Chandel, Gaber El-Saber Batiha, Simona Cavalu","doi":"10.2174/1872208316666220512113921","DOIUrl":"10.2174/1872208316666220512113921","url":null,"abstract":"Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore,\u0000the article has been withdrawn.Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/\u0000editorial-policies-main.php.Bentham science disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will\u0000not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or\u0000table that has been published elsewhere must be reported, and copyright permission for reproduction must\u0000be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree\u0000that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated\u0000information is discovered. By submitting a manuscript the authors agree that the copyright of their\u0000article is transferred to the publishers if and when the article is accepted for publication.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10788401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro florigenesis with special reference to orchids- A Review. 兰花体外开花研究进展。

Recent patents on biotechnology Pub Date : 2022-04-15 DOI: 10.2174/1872208316666220415124439

S. Kaur

引用次数: 1

The Effects of Amino acids, Phenols and Protein Hydrolysates as Biostimulants on Sustainable Crop Production and Alleviate Stresses. 氨基酸、酚类和蛋白质水解物作为生物刺激剂对作物可持续生产和缓解胁迫的影响。

Recent patents on biotechnology Pub Date : 2022-04-12 DOI: 10.2174/1872208316666220412133749

M. H. Shahrajabian, Q. Cheng, Wenli Sun

{"title":"The Effects of Amino acids, Phenols and Protein Hydrolysates as Biostimulants on Sustainable Crop Production and Alleviate Stresses.","authors":"M. H. Shahrajabian, Q. Cheng, Wenli Sun","doi":"10.2174/1872208316666220412133749","DOIUrl":"https://doi.org/10.2174/1872208316666220412133749","url":null,"abstract":"Biostimulants which contain substances or products including natural compounds, special formulation and microorganisms have gained a considerable attention as sustainable method for heavy metal detoxification, stimulate natural toxins, controlling diseases and pests, may increase both water and nutrient efficiency. Biostimulants are important products in modern agriculture which composed of different heterogenous classes of compounds with a broad spectrum of action to increase both qualitative and quantitative productions. Amino acids can be useful in stress defence, photosynthesis, increase nutrient uptake, pollination and fruit formation, precursors to hormones and growth parameters. Amino acids are considered as precursors and constituents of proteins, which are well-known for stimulation of cell growth. Because, they are the basic building blocks of proteins, amino acids are very important in plant growth, development and metabolite synthesis. One of the diverse, notable and the large group of secondary metabolites is phenolic compounds which have important function in regulation of the plants physiological activities, oxidation-reduction processes and photosynthesis. Protein hydrolysates contain amino acids and peptides which is one of the most important kinds of biostimulants. Protein hydrolysates have notable capability to increase crop performance, particularly under environmental stress conditions. This review article is aimed to introduce and found more about the roles of different types of biostimulants on plant growth and final yield production with considering sustainable agriculture.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48741587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Alzheimer's Disease: A Silent Pandemic - A Systematic Review on the Situation and Patent Landscape of the Diagnosis. 阿尔茨海默病:一场无声的大流行——对阿尔茨海默病诊断现状和专利前景的系统回顾。

Recent patents on biotechnology Pub Date : 2022-04-08 DOI: 10.2174/1872208316666220408114129

L. D. Goyzueta-Mamani, Miguel Angel Chávez-Fumagalli, Karla L. Alvarez-Fernandez, J. Aguilar-Pineda, Rita Nieto-Montesinos, G. Davila Del-Carpio, K. J. Vera-López, C. L. Lino Cardenas

{"title":"Alzheimer's Disease: A Silent Pandemic - A Systematic Review on the Situation and Patent Landscape of the Diagnosis.","authors":"L. D. Goyzueta-Mamani, Miguel Angel Chávez-Fumagalli, Karla L. Alvarez-Fernandez, J. Aguilar-Pineda, Rita Nieto-Montesinos, G. Davila Del-Carpio, K. J. Vera-López, C. L. Lino Cardenas","doi":"10.2174/1872208316666220408114129","DOIUrl":"https://doi.org/10.2174/1872208316666220408114129","url":null,"abstract":"BACKGROUND\u0000Alzheimer's disease (AD) is characterized by cognitive impairment, tau protein deposits, and amyloid beta plaques. AD impacted 44 million people in 2016, and it is estimated to affect 100 million people by 2050. AD is disregarded as a pandemic compared with other diseases. To date, there is no effective treatment or diagnosis.\u0000\u0000\u0000OBJECTIVE\u0000We aimed to discuss the current tools used to diagnose COVID-19, to point out their potential to be adapted for AD diagnosis, and to review the landscape of existing patents in the AD field and future perspectives for AD diagnosis.\u0000\u0000\u0000METHOD\u0000We carried out a scientific screening following a research strategy in PubMed; Web of Science; the Derwent Innovation Index; the KCI-Korean Journal Database; SciELO; the Russian Science Citation index; and the CDerwent, EDerwent, and MDerwent index databases.\u0000\u0000\u0000RESULTS\u0000A total of 326 from 6,446 articles about AD and 376 from 4,595 articles about COVID-19 were analyzed. Of these, AD patents were focused on biomarkers and neuroimaging with no accurate, validated diagnostic methods, and only 7% of kit development patents were found. In comparison, COVID-19 patents were 60% about kit development for diagnosis; they are highly accurate and are now commercialized.\u0000\u0000\u0000CONCLUSION\u0000AD is still neglected and not recognized as a pandemic that affects the people and economies of all nations. There is a gap in the development of AD diagnostic tools that could be filled if the interest and effort that has been invested to tackle the COVID-19 emergency could also be applied for innovation.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47014697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herd Immunity against Coronavirus: A Review. 群体对冠状病毒的免疫：综述。

Recent patents on biotechnology Pub Date : 2022-04-08 DOI: 10.2174/1872208316666220408113002

S. Datta, A. Roy

引用次数: 1

Coronavirus-A Crippling Affliction to Humans. 冠状病毒——人类的一大痛苦。

Recent patents on biotechnology Pub Date : 2022-04-04 DOI: 10.2174/1872208316666220404103033

Rimple Kaul, S. Devi

{"title":"Coronavirus-A Crippling Affliction to Humans.","authors":"Rimple Kaul, S. Devi","doi":"10.2174/1872208316666220404103033","DOIUrl":"https://doi.org/10.2174/1872208316666220404103033","url":null,"abstract":"Coronaviruses hold idiosyncratic morphological features and functionality. The members of this group have a remarkable capability of infecting both animals and humans. Inimitably, the replication of the RNA genome continues through the set of viral mRNA molecules. Coronaviruses received the least attention until 2003 since they caused only minor respiratory tract illnesses. However, this changed exclusively with the introduction of zoonotic SARS-CoV in 2003. In 2012, MERS-CoV emerged and confirmed this group of viruses as the major causative agents of severe respiratory tract illness. Today, Coronavirus Disease 2019 (i.e., COVID-19) has turned out to be a chief health problem that causes a severe acute respiratory disorder in humans. Since the first identification of COVID-19 in December 2019 in Wuhan, China, this infection has devastatingly spread all around the globe leading to a crippling affliction for humans. The strain is known as the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), and WHO (the World Health Organization) has termed this new pandemic disease as Coronavirus Disease (COVID-19). COVID-19 is still spreading, with an estimated 136 million confirmed cases and more than 2.94 million deaths worldwide so far while the pandemic is still going on. In the current scenario, there is no particular treatment for COVID-19, however remarkable efforts for immunization and vaccine development can be observed. Therefore, the execution of precautions and proper preventive measures are indispensable to minimize and control the community transmission of the virus. This review summarizes information about the pathophysiology, transmission, symptoms, and the host defense mechanism as well as immunization and vaccine development against COVID-19.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42392132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Meet the Editorial Board Member 会见编辑委员会成员

Recent patents on biotechnology Pub Date : 2022-04-01 DOI: 10.2174/187220831601220408113712

E. Jirillo

引用次数: 0

Evidence and Updates on non-dairy synbiotic beverage development. 非乳制品合生元饮料开发的证据和最新进展。

Recent patents on biotechnology Pub Date : 2022-03-03 DOI: 10.2174/1872208316666220303095807

Rhaissa Coelho Andrade, Caroline Santana Figueredo, Janaína de Carvalho Alves, M. N. Roselino

{"title":"Evidence and Updates on non-dairy synbiotic beverage development.","authors":"Rhaissa Coelho Andrade, Caroline Santana Figueredo, Janaína de Carvalho Alves, M. N. Roselino","doi":"10.2174/1872208316666220303095807","DOIUrl":"https://doi.org/10.2174/1872208316666220303095807","url":null,"abstract":"BACKGROUND\u0000With the increase in cases of intolerance and allergies to milk protein, new food possibilities have been studied as an alternative to dairy drinks in order to meet the needs of this population, such as, non-dairy synbiotic drinks.\u0000\u0000\u0000OBJECTIVE\u0000The aim of this study was to carry out an integrative literature review on the main types of non-dairy synbiotic beverages, in order to investigate the probiotics and prebiotics added to them. Besides, we also looked into the characteristics of the substrates and fermentation conditions (temperature, time and pH), to assess the influences on bacterial viability, consumer acceptance, conservation and antimicrobial action.\u0000\u0000\u0000METHODS\u0000We conducted an integrative review of articles published on Pubmed, Web of Science, Scielo, Scopus and Capes journal in the last five years, using the following terms: symbiotic drink, symbiotic beverage, synbiotic drink, synbiotic beverage, bebida simbiótica, not kombucha, which after reading, resulted in the inclusion of 28 articles.\u0000\u0000\u0000RESULTS\u0000As expected, the main probiotics used were from the genera Lactobacillus and Bifidobacterium, and the prebiotics were inulin and fructooligosaccharide. It is noteworthy that all analyzed beverages were in fact probiotics since they obtained values above the minimum viability of 6 log CFU / mL, consequently, they can bring benefits to consumers.\u0000\u0000\u0000CONCLUSION\u0000Thus, beyond fruits and vegetables being rich sources of nutrients, they also enable the development of synbiotic drinks delivered from their substrates, being an alternative for the public with restrictions to milk.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45997925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Use of patent information to characterize trends in the therapeutic applications of extracellular vesicles derived from mesenchymal stem cells (MSC-EVs). 利用专利信息描述间充质干细胞(msc - ev)衍生的细胞外囊泡治疗应用的趋势。

Recent patents on biotechnology Pub Date : 2022-03-03 DOI: 10.2174/1872208316666220303095217

Ángela Ponce-Polo, Alvaro RitoréHidalgo, Arturo Argüello Martínez, Roke Iñaki Oruezabal Guijarro

{"title":"Use of patent information to characterize trends in the therapeutic applications of extracellular vesicles derived from mesenchymal stem cells (MSC-EVs).","authors":"Ángela Ponce-Polo, Alvaro RitoréHidalgo, Arturo Argüello Martínez, Roke Iñaki Oruezabal Guijarro","doi":"10.2174/1872208316666220303095217","DOIUrl":"https://doi.org/10.2174/1872208316666220303095217","url":null,"abstract":"Extracellular vesicles derived from mesenchymal stromal cells (MSC-EVs) are gaining interest for medical purposes. The promising therapeutic effects exhibited in both preclinical and clinical studies suggest that they may become an alternative for certain applications to cell-based therapies, which are subjected to stricter regulations. The commercial exploitation of these candidates requires a proper patent strategy from both the industry and public research organizations. Here, we raise a global patent literature analysis to identify key players and therapeutic applications in the field. Our results show an increasing rate of patent publications since 2009, with Asia (specifically China) leading the patenting activity. The therapeutic use of MSC-EVs within patent literature covers a wide range of diseases, in which \"Dermal and Wounds\", \"Neurology\" and \"Cardiovascular\" are the main therapeutic areas. Moreover, most of these patents include \"product-by-process\" claims, since the therapeutic effects of MSC-EVs could be influenced by their manufacturing process. Our results follow scientific and clinical literature trends.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47944454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges and approaches of drugs such as Memantine, Donepezil, Rivastigmine and Aducanumab in the treatment, control and management of Alzheimer's disease. 美金刚、多奈哌齐、利瓦斯蒂明和阿杜坎单抗等药物在阿尔茨海默病治疗、控制和管理中的挑战和方法。

Recent patents on biotechnology Pub Date : 2022-03-02 DOI: 10.2174/1872208316666220302115901

Mohammad Saeedi, F. Mehranfar

{"title":"Challenges and approaches of drugs such as Memantine, Donepezil, Rivastigmine and Aducanumab in the treatment, control and management of Alzheimer's disease.","authors":"Mohammad Saeedi, F. Mehranfar","doi":"10.2174/1872208316666220302115901","DOIUrl":"https://doi.org/10.2174/1872208316666220302115901","url":null,"abstract":"Alzheimer's disease (AD) is a kinds of neuropsychiatric illnesses that affect the central nervous system. In this disease, the accumulation of amyloid-beta increases, and phosphorylated tau (P-tau) protein, one of the ways to treat this disease is to reduce the accumulation of amyloid-beta. Various studies have demonstrated that pharmacological approaches have considerable effects in the treatment of AD, despite the side effects and challenges. Cholinesterase inhibitors and the NMDA receptor antagonist memantine are presently authorized therapies for AD. Memantine and Donepezil are the most common drugs for the prevention and therapy of AD with mechanisms such as lessened β-amyloid plaque, effect on N-Methyl-D-aspartate (NMDA) receptors. Diminution glutamate and elevated acetylcholine are some of the influences of medications administrated to treat AD, and drugs can also play a role in slowing the progression of cognitive and memory impairment. A new pharmacological approach and strategy is required to control the future of AD. This review appraises the effects of memantine, donepezil, rivastigmine, and aducanumab in clinical trials, in vitro and animal model studies that have explored how these drugs versus AD development and also discuss possible mechanisms of influence on the brain. Research in clinical trials has substantial findings that support the role of these medications in AD treatment and ameliorate the safety and efficacy of AD therapy, although more clinical trials are required to prove their effectiveness.","PeriodicalId":21064,"journal":{"name":"Recent patents on biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47012328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9