Reproductive and Developmental Medicine最新文献_第5页

Association of sleep characteristics and night shift work with self-reported diagnosis of polycystic ovary syndrome: a questionnaire-based cross-sectional study 睡眠特征和夜班工作与多囊卵巢综合征自我报告诊断的关联:一项基于问卷的横断面研究

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-10-21 DOI: 10.1097/RD9.0000000000000051

Shuyi Shao, Huanhuan Zhao, Zhi-ying Lu, Xiaorong Lei, Ying Zhang

{"title":"Association of sleep characteristics and night shift work with self-reported diagnosis of polycystic ovary syndrome: a questionnaire-based cross-sectional study","authors":"Shuyi Shao, Huanhuan Zhao, Zhi-ying Lu, Xiaorong Lei, Ying Zhang","doi":"10.1097/RD9.0000000000000051","DOIUrl":"https://doi.org/10.1097/RD9.0000000000000051","url":null,"abstract":"Objective: To examine the association between sleep characteristics and night shift work and the risk of polycystic ovary syndrome (PCOS) in Chinese women and to investigate their relationship with infertility in PCOS. Methods: From March 21, 2021 to April 31, 2021, 3927 Chinese women with or without PCOS were recruited online. All participants completed WeChat-based electronic questionnaires. Sleep characteristics were measured using the Pittsburgh sleep quality index. Results: A total of 2871 women were included in the final analysis. Sleep duration (odds ratio [OR], 0.857; 95% confidence interval [CI], 0.763–0.963), sleep midpoint (OR, 1.142; 95% CI, 1.049–1.244), sleep disturbance (OR, 1.320; 95% CI, 0.957–1.146), daytime dysfunction (OR, 1.136; 95% CI, 1.030–1.253), and night shift work (OR, 1.628; 95% CI, 1.264–2.097) were associated with a higher risk of PCOS. After adjusting for confounders, including age, body mass index, smoking status, and coffee and tea drinking status, sleep disturbance (OR, 1.314; 95% CI, 1.111–1.555), daytime dysfunction (OR, 1.143; 95% CI, 1.034–1.264), and night shift work (OR, 1.800; 95% CI, 1.388–2.333) remained associated. In addition, sleep disturbance (OR, 1.887; 95% CI, 1.400–2.542) and subjective sleep quality (OR, 1.299; 95% CI, 1.037–1.627) were associated with infertility in women with PCOS, and sleep disturbance (OR, 1.750; 95% CI, 1.281–2.390) remained significant after adjusting for confounders. Conclusions: Sleep disturbance, daytime dysfunction, and night shift work are significantly associated with PCOS. Screening for sleep disturbances and providing appropriate treatment could be potential strategies for managing PCOS and its long-term complications.","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":"7 1","pages":"50 - 55"},"PeriodicalIF":0.8,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42608942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The perivascular niche of endometrial mesenchymal stromal/stem-like cells 子宫内膜间充质基质/干细胞样细胞的血管周围生态位

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/RD9.0000000000000038

R. Chan, Tian-Qi Li, Sisi Zhang, Yuan Fang, Jingxuan Xu

引用次数: 0

Reliability and validity of generalized anxiety disorder 7-item scale in early pregnant women 早期妊娠妇女广泛性焦虑障碍7项量表的信度和效度

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/RD9.0000000000000046

Li-li Gong, Xiaodi Xie, Si-Tong Liu, Weihong Hu, Yu-Jie Niu, Yi Sun, Jun-sheng Liu, X. Xia

{"title":"Reliability and validity of generalized anxiety disorder 7-item scale in early pregnant women","authors":"Li-li Gong, Xiaodi Xie, Si-Tong Liu, Weihong Hu, Yu-Jie Niu, Yi Sun, Jun-sheng Liu, X. Xia","doi":"10.1097/RD9.0000000000000046","DOIUrl":"https://doi.org/10.1097/RD9.0000000000000046","url":null,"abstract":"Objective: This study aimed to evaluate the structural reliability and validity of generalized anxiety disorder 7-item (GAD-7) scale in early pregnant women. Methods: In this cross-sectional study, 30,823 patients in early pregnancy registered in the Obstetrics and Gynecology Hospital of Fudan University completed the GAD-7 scale and patient health questionnaire-9 item (PHQ-9). The discriminative ability, reliability, construct validity, and criterion validity were assessed to evaluate the psychometric properties and factor structures. Items with a discrimination parameter (α) of <0.65, factor loading of <0.30, or cross loading of >0.40 in two or more factors simultaneously were deleted from the scale. Results: All GAD-7 scale items exhibited a high discrimination power. The reliability of the GAD-7 scale was good (Cronbach’s alpha coefficient = 0.891). Exploratory factor analysis extracted one factor with eigenvalues of greater than 1.0, which explained 61.930% of the common variance. Confirmatory factor analysis confirmed that the one-factor structure fitted the data well. The correlation coefficient with the PHQ-9 was 0.639. Conclusion: The Chinese version of the GAD-7 scale can be used as a screening tool for early pregnant women. It performs well in terms of discriminative ability, reliability, construct validity, and criterion validity. Pregnant women who screen positive may require more attention and investigation to confirm the presence of generalized anxiety disorder.","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":"6 1","pages":"249 - 253"},"PeriodicalIF":0.8,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43270023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating Chromosomal Segregation in a Family Where Both Spouses Carry an Autosomal Translocation 评估一个配偶均携带常染色体易位的家族的染色体分离

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/rd9.0000000000000041

I. L. Puppo, Z. Tonyan, A. Saifitdinova, J. A. Loginova, A. Kinunen, A. N. Panina, Julia R. Pastuhova, O. A. Leonteva, O. Chiryaeva, Olga V. Маlysheva, O. Glotov, I. V. Poliakova, A. Tikhonov, T. Vavilova, I. Menshikova, Elvira V. Isakova, A. Glotov, Natalya K. Bichevaya

引用次数: 0

Single-cell analysis in endometrial research 子宫内膜研究中的单细胞分析

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/RD9.0000000000000037

Dan Cao, Jue Wang, Yuan Yao, W. Yeung

引用次数: 0

Single-cell sequencing analysis of the maternal–fetal interface 母胎界面单细胞测序分析

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/rd9.0000000000000045

Pei-Ru Wei, Yi-Hua Yang

引用次数: 1

Preimplantation genetic testing for aneuploidy improves clinical outcomes in patients with repeated implantation failure 非整倍体植入前基因检测可改善重复植入失败患者的临床结果

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/RD9.0000000000000043

Ruihuan Gu, Jing Fu, Naidong Ge, Zhichao Li, Bin Huang, Yan Xu, Yao-Yu Zou, Lu Li, Yi-juan Sun, Xiao-Xi Sun

{"title":"Preimplantation genetic testing for aneuploidy improves clinical outcomes in patients with repeated implantation failure","authors":"Ruihuan Gu, Jing Fu, Naidong Ge, Zhichao Li, Bin Huang, Yan Xu, Yao-Yu Zou, Lu Li, Yi-juan Sun, Xiao-Xi Sun","doi":"10.1097/RD9.0000000000000043","DOIUrl":"https://doi.org/10.1097/RD9.0000000000000043","url":null,"abstract":"Objective: The objective of this study is to study whether preimplantation genetic testing for aneuploidy (PGT-A) improves the clinical outcomes of infertile patients with repeated implantation failure (RIF) undergoing frozen-thawed embryo transfer. Methods: This is a retrospective analysis of clinical pregnancy, live birth, miscarriage rates, and obstetric and perinatal outcomes of women with RIF with or without PGT-A. Statistical analyses of categorical data were performed using propensity score matching (PSM), χ2 test, and Student’s t test. Results: We enrolled 466 patients with RIF, of which, 209 were in the RIF-PGT-A group. The rate of euploid blastocysts was significantly associated with age and day 5 or 6 blastocysts. There were significant differences between the RIF-PGT-A group and the RIF-non-PGT-A group across several parameters. After PSM, positive serum human chorionic gonadotropin (56.9% and 33.9%, P <0.01), clinical pregnancy (49.5% and 31.2%, P <0.01), live birth (43.1% and 25.7%, P <0.01), and fetal heart rates (50.0% and 29.8%, P <0.01) per transfer were significantly higher in the RIF-PGT-A group. Conclusion: Elective single-embryo transfer PGT-A can minimize the risk of obstetric and perinatal outcomes, especially fetal body weight, in women with RIF. Additionally, PGT-A can significantly improve pregnancy and live birth rates.","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":"7 1","pages":"12 - 19"},"PeriodicalIF":0.8,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46433089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blastocyst-like embryo surrogates from stem cells in implantation models 胚胎植入模型中干细胞的芽细胞样胚胎替代物

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/rd9.0000000000000042

S. Tian, H. Ruan, W. Yeung, Yin-Lau Lee

引用次数: 0

Changes in human sperm motility and DNA fragmentation index after incubation at different temperatures following density gradient centrifugation and swim-up procedures 在密度梯度离心和游泳程序下，不同温度孵育后人类精子活力和DNA断裂指数的变化

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/RD9.0000000000000039

Yan-Nan Yang, Ling Wang, Yubao Liu, Yun-jing Xue, Chen-Chen Liu, Fei Shi, Xue Dai, R. Chian

{"title":"Changes in human sperm motility and DNA fragmentation index after incubation at different temperatures following density gradient centrifugation and swim-up procedures","authors":"Yan-Nan Yang, Ling Wang, Yubao Liu, Yun-jing Xue, Chen-Chen Liu, Fei Shi, Xue Dai, R. Chian","doi":"10.1097/RD9.0000000000000039","DOIUrl":"https://doi.org/10.1097/RD9.0000000000000039","url":null,"abstract":"Objective: The purpose of this study was to evaluate the sperm motility and DNA integrity at different temperatures to analyze whether the sperms are suitable on the second day for insemination of in vitro matured oocytes by intra-cytoplasmic sperm injection (ICSI) following density gradient centrifugation (DGC) and swim-up (SU) procedures. Methods: Semen samples were collected from 30 outpatients who visited the Center for Reproductive Medicine for semen analyses. Following sperm selection by DGC and SU procedures, the liquified semen samples were divided into three groups and incubated at 4, 25, and 37°C, respectively. Following incubation for 24, 48, and 72 hours, the sperm motility and sperm DNA fragmentation index (DFI) were analyzed. Results: Following the combination of DGC and SU procedures, the sperm motility (91.8% ± 8.6% vs. 50.8% ± 13.1%) and DFI (5.1% ± 7.9% vs. 13.0% ± 11.6%) were significantly improved (P <0.01) compared to those without any treatment. The sperm motility of the 3 groups significantly declined (P <0.05) post-incubation compared to that of the groups prior incubation. However, sperm motility significantly increased (76.9% ± 10.4%) (P <0.05) at 25°C compared to that of the other 2 groups (53.5% ± 11.0% and 47.6% ± 10.2%). Sperm DFI significantly increased (P <0.05) at 37°C following incubation for 24 and 72 hours in comparison to that of the other 2 groups. However, the sperm DFI did not significantly increase when the sperm samples were incubated at 4 (5.7% ± 5.9%) and 25°C (6.8% ± 5.6%) for 24 hours compared to that before incubation (5.1% ± 7.9%). Conclusions: These results indicate that the sperm quality, in terms of motility and DFI, can be efficiently improved by DGC in combination with SU. Following which, the sperm samples can be incubated at 25°C and be used on the second day for insemination of in vitro matured oocytes by ICSI.","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":"6 1","pages":"243 - 248"},"PeriodicalIF":0.8,"publicationDate":"2022-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48151259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Organoids as a model to study the human endometrium 类器官作为研究人类子宫内膜的模型

IF 0.8 4区医学

Reproductive and Developmental Medicine Pub Date : 2022-09-21 DOI: 10.1097/rd9.0000000000000040

Jian-Lin Li, Leqian Lin, Jiangming Zhong, Xintong Li, Cheuk-Lun Lee, P. Chiu

引用次数: 1