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MRI-directed Micro-US-guided Transperineal Focal Laser Ablation for Localized Prostate Cancer: A 1-year Follow-up Study.
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.233371
Franҫois Cornud, Katelijne de Bie, Luigi van Riel, Arnaud Lefèvre, Philippe Camparo, Marc Galiano
{"title":"MRI-directed Micro-US-guided Transperineal Focal Laser Ablation for Localized Prostate Cancer: A 1-year Follow-up Study.","authors":"Franҫois Cornud, Katelijne de Bie, Luigi van Riel, Arnaud Lefèvre, Philippe Camparo, Marc Galiano","doi":"10.1148/radiol.233371","DOIUrl":"https://doi.org/10.1148/radiol.233371","url":null,"abstract":"<p><p>Background MRI-guided focal laser ablation (FLA) is a promising treatment in localized prostate cancer (PCa). MRI-guided micro-US FLA shows potential for outpatient use, but its clinical application remains unexplored. Purpose To evaluate the safety, feasibility, and 12-month functional and oncologic outcomes of MRI-guided micro-US transperineal FLA in localized PCa and to assess the accuracy of micro-US in showing lesions depicted at MRI with Prostate Imaging Reporting and Data System (PI-RADS) score of 3 or higher. Materials and Methods This prospective, single-center observational study (July 2020 to June 2023) included participants with localized low- or intermediate-risk PCa and PI-RADS 3 or higher lesions (≤20 mm). Single- or multifiber FLA was performed at 1064 nm, guided by MRI-delineated image fusion. At 12 months, recurrence rates, complications, erectile function scores, and urinary symptom scores were assessed. Mann-Whitney <i>U</i> and Wilcoxon tests were used for comparisons. Results Fifty-five male participants (median age, 70 years; IQR, 62-74 years) with 58 lesions that were PI-RADS 3 or higher underwent transperineal FLA, with a 12-month follow-up for 33 participants. The median prostate-specific antigen level was 7.0 ng/mL (IQR, 5.6-9.0 ng/mL), 43 of 58 lesions (74%) had a Gleason score of 3 + 4, and 10 of 58 lesions (17%) had a Gleason score of 3 + 3. Single-fiber and multifiber FLA were used to treat 21 of 58 (36%) and 37 of 58 (64%) tumors, respectively. At micro-US, 53 of 58 (91%) tumors were successfully visualized. Multifiber FLA produced larger ablation volumes than did single-fiber treatment (median, 15 mL [IQR, 8-22 mL] vs 4.5 mL [IQR, 2.8-9.2 mL]; <i>P</i> < .001). At 12 months, biopsies in 35 treated tumors showed 17 recurrences (49%), including 13 in-field and four out-of-field recurrences. In-field recurrences occurred in 10 of 18 (56%) single-fiber and three of 17 (18%) multifiber cases. At 12 months, erectile function scores decreased compared with baseline (median International Index of Erectile Function score, 19 [IQR, 12-24] vs 21 [IQR, 15-24]; <i>P</i> < .001), whereas urinary function remained stable (median International Prostatic Symptom Score, 2 [IQR, 2-9] vs 6 [IQR, 3-11]; <i>P</i> = .72). One rectoprostatic fistula developed and required surgery. Conclusion Multifiber micro-US-guided FLA was safe and feasible, with 18% recurrence at 1-year follow-up. Clinical trial registration no. NCT05163197 © RSNA, 2024 <i>Supplemental material is available for this article.</i></p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e233371"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Power Outage: Mitochondrial Dysfunction in Long COVID Measured Using 1H and 31P MR Spectroscopy.
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.242833
Grace Parraga, Rachel L Eddy
{"title":"Power Outage: Mitochondrial Dysfunction in Long COVID Measured Using <sup>1</sup>H and <sup>31</sup>P MR Spectroscopy.","authors":"Grace Parraga, Rachel L Eddy","doi":"10.1148/radiol.242833","DOIUrl":"https://doi.org/10.1148/radiol.242833","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e242833"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Top Publications in Radiology, 2024.
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.243436
Linda Moy
{"title":"Top Publications in <i>Radiology</i>, 2024.","authors":"Linda Moy","doi":"10.1148/radiol.243436","DOIUrl":"https://doi.org/10.1148/radiol.243436","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e243436"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expanding Cryoneurolysis to Refractory Ventricular Arrhythmias. 将冷冻神经溶解术扩展到难治性室性心律失常。
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.242977
Farah Cadour, Ugo Scemama
{"title":"Expanding Cryoneurolysis to Refractory Ventricular Arrhythmias.","authors":"Farah Cadour, Ugo Scemama","doi":"10.1148/radiol.242977","DOIUrl":"https://doi.org/10.1148/radiol.242977","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e242977"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant Thrombus in a Coronary Artery Bypass Graft: Comparison of Photon-counting Detector CT and Energy-integrating Detector CT.
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.241326
Huixin Zhang, Dongsheng Jin
{"title":"Giant Thrombus in a Coronary Artery Bypass Graft: Comparison of Photon-counting Detector CT and Energy-integrating Detector CT.","authors":"Huixin Zhang, Dongsheng Jin","doi":"10.1148/radiol.241326","DOIUrl":"https://doi.org/10.1148/radiol.241326","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e241326"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Imaging in Diagnosis of Small Airway Disease.
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.243461
Evan C Unger
{"title":"Role of Imaging in Diagnosis of Small Airway Disease.","authors":"Evan C Unger","doi":"10.1148/radiol.243461","DOIUrl":"https://doi.org/10.1148/radiol.243461","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e243461"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methodological Challenges in Evaluating Large Language Models in Radiology. 评估放射学大型语言模型的方法挑战。
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.241711
David Li, Woojin Kim, Paul H Yi
{"title":"Methodological Challenges in Evaluating Large Language Models in Radiology.","authors":"David Li, Woojin Kim, Paul H Yi","doi":"10.1148/radiol.241711","DOIUrl":"https://doi.org/10.1148/radiol.241711","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e241711"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum for: Diagnosis Please Certificates of Recognition Awarded to Five Individuals and to International and North American Radiology Resident Groups.
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.249022
David H Ballard, Linda Moy, Vicky Goh
{"title":"Erratum for: Diagnosis Please Certificates of Recognition Awarded to Five Individuals and to International and North American Radiology Resident Groups.","authors":"David H Ballard, Linda Moy, Vicky Goh","doi":"10.1148/radiol.249022","DOIUrl":"https://doi.org/10.1148/radiol.249022","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e249022"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis Please Certificates of Recognition Awarded to Five Individuals and to International and North American Radiology Resident Groups.
IF 12.1 1区 医学
Radiology Pub Date : 2024-12-01 DOI: 10.1148/radiol.243286
David H Ballard, Linda Moy, Vicky Goh
{"title":"Diagnosis Please Certificates of Recognition Awarded to Five Individuals and to International and North American Radiology Resident Groups.","authors":"David H Ballard, Linda Moy, Vicky Goh","doi":"10.1148/radiol.243286","DOIUrl":"10.1148/radiol.243286","url":null,"abstract":"","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 3","pages":"e243286"},"PeriodicalIF":12.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142771805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CT-guided Coaxial Lung Biopsy: Number of Cores and Association with Complications. CT 引导下同轴肺活检:取芯数量及其与并发症的关系
IF 12.1 1区 医学
Radiology Pub Date : 2024-11-01 DOI: 10.1148/radiol.232168
Charissa R Kim, Mehmet Ali Sari, Elena Grimaldi, Paul A VanderLaan, Alexander Brook, Olga R Brook
{"title":"CT-guided Coaxial Lung Biopsy: Number of Cores and Association with Complications.","authors":"Charissa R Kim, Mehmet Ali Sari, Elena Grimaldi, Paul A VanderLaan, Alexander Brook, Olga R Brook","doi":"10.1148/radiol.232168","DOIUrl":"https://doi.org/10.1148/radiol.232168","url":null,"abstract":"<p><p>Background Percutaneous CT-guided lung core-needle biopsy is a frequently performed and generally safe procedure. However, with advances in the management of lung cancer, there is a need for a greater amount of tissue for tumor genomic profiling and characterization. Purpose To determine whether the number of core samples obtained with percutaneous CT-guided lung biopsy is associated with postprocedural complications. Materials and Methods This retrospective study included consecutive patients who underwent percutaneous CT-guided coaxial lung core-needle biopsy for suspected primary lung cancer between November 2012 and August 2023 at an academic tertiary referral hospital. Patient data from medical records were collected, including demographics, lesion size and distance from pleura, and number of obtained biopsy samples. Postprocedural complications of pneumothorax, chest tube placement, perilesional hemorrhage, and hemoptysis were recorded. Multivariable logistic regression models were used to assess whether the number of cores was a predictive factor for lung biopsy complications. Results A total of 827 patients (mean age, 70.9 years ± 9.6 [SD]; 474 [57.3%] female patients) were included. The median lesion size was 22 mm (IQR, 15-34 mm), with 517 of 827 (62.5%) patients diagnosed with lung adenocarcinoma. Pneumothorax was noted in 171 of 827 (20.7%) patients, with a chest tube placed in 32 of 827 (3.9%), perilesional hemorrhage in 353 of 827 (42.7%), and hemoptysis in 20 of 827 (2.4%) patients. The median number of samples obtained was four (range, one to 12). Multivariable analysis showed no evidence of an association between the number of core samples obtained and any complications: pneumothorax (coefficient, -0.02; <i>P</i> = .81), chest tube (coefficient, 0.18; <i>P</i> = .26), perilesional hemorrhage (coefficient, -0.03; <i>P</i> = .63), or hemoptysis (coefficient, -0.10; <i>P</i> = .60). Conclusion In patients suspected of having lung cancer who underwent percutaneous CT-guided coaxial lung core biopsy, there was no evidence of an association between the number of core biopsy samples obtained and any postprocedural complications. © RSNA, 2024 See also the editorial by Zuckerman in this issue.</p>","PeriodicalId":20896,"journal":{"name":"Radiology","volume":"313 2","pages":"e232168"},"PeriodicalIF":12.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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