Psychoneuroendocrinology最新文献

{"title":"Hair cortisol measurement: A systematic review of current practices and a proposed checklist for reporting standards","authors":"Thais Martins-Silva ,&nbsp;Rafaela Costa Martins ,&nbsp;Joseph Murray ,&nbsp;Andressa Marques Carvalho ,&nbsp;Letícia Neutzling Rickes ,&nbsp;Beatriz de Freitas Corrêa ,&nbsp;Brenda Barbon Fraga ,&nbsp;Clarice Brinck Brum ,&nbsp;Deise Farias Freitas ,&nbsp;Fernando Diógenes Teixeira Meyer ,&nbsp;Marina Xavier Carpena ,&nbsp;Laura Moreira Goularte ,&nbsp;Andrea Gonzalez ,&nbsp;Isabel Oliveira de Oliveira ,&nbsp;Luciana Tovo-Rodrigues","doi":"10.1016/j.psyneuen.2024.107185","DOIUrl":"10.1016/j.psyneuen.2024.107185","url":null,"abstract":"<div><div>Summarising hair cortisol concentration (HCC) methodology may provide much-needed data toward protocol standardisation to maximise future comparability of findings across studies. We searched five electronic databases, reviewing 11,716 publications focused on protocols previously used to measure hair cortisol. Our aim was to determine the frequency with which each procedure was reported in the literature. We then conducted a meta-analysis of the HCC results and proposed a checklist for reporting methodological procedures related to HCC. Using pre-selected key terms, we searched for population-based, non-experimental studies reporting HCC outcomes published up to November 2023. Eighty-seven analytical samples were included in the qualitative analysis and 28 in the quantitative analysis. The analyzed studies predominantly included children (≤10 years; 45.4 %) and mainly involved participants from European populations (72.6 %). There was significant variation in hair sample collection procedures across the studies. Most used hair samples up to 3 cm in length (92 %), with around one-third employing either milled (33.3 %) or minced (29.9 %) as grinding methods. For quantification, LC-MS was the most common method (47.1 %), followed by ELISA (24.1 %). Meta-analysis showed significant variability in the mean HCC observed. Meta-regression showed no association between differences in methodology and HCC. In conclusion, the absence of a standardized protocol in HCC research may result in procedural variability, making it difficult to compare findings across studies. Many published studies lacked sufficient detail in describing their methods. To address this, we propose a checklist of reporting guidelines for measurement procedures related to HCC.</div></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary and secondary allostatic processes in the context of high-stress work: A multigroup moderation from the English longitudinal study of ageing","authors":"Thomas O’Toole ,&nbsp;Christopher J. Armitage ,&nbsp;Martie van Tongeren ,&nbsp;Kimberly A. Dienes","doi":"10.1016/j.psyneuen.2024.107193","DOIUrl":"10.1016/j.psyneuen.2024.107193","url":null,"abstract":"<div><div>Evidence suggests that chronic cortisol excess may precede the development of an allostatic load, and that this association may be influenced by the level of work stress. This study aims to investigate the associations between hair cortisol concentration and the development of systemic allostatic load cross-sectionally and at a lag of four years, stratified by level of effort-reward imbalance.</div><div>The sample consisted of respondents from the English Longitudinal Study of Ageing (ELSA) who were in employment with hair cortisol measurements at baseline (wave 6), and allostatic load markers at baseline and follow-up (wave 8; n=411; 64 % female). Hair cortisol was used as a measure of total cortisol expression over the preceding two months. Allostatic load was modelled as a count-based index using nine markers; three per system, across the immune, metabolic and cardiovascular systems. This model was then grouped by a median-cut effort reward-imbalance scale (0.83) and regression pathways were compared between groups using a series of Chi-Squared tests of difference.</div><div>Results provide evidence that higher hair cortisol concentrations predict an increase in immune and cardiovascular allostatic load cross-sectionally, and a metabolic allostatic load at a lag of four years. These pathways were found in the high effort-reward imbalance group, but not in the low effort-reward imbalance group. There were also significant differences found between groups for hair cortisol concentration as a predictor of concurrent immune and cardiovascular allostatic load</div><div>Findings may indicate a novel temporality to the accumulation of an allostatic load, and that the “tipping point” between allostasis and allostatic load may lie within the ability of the HPA axis to regulate the cardiovascular system concurrently, with longitudinal consequences for metabolic syndrome indicators.</div></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142506748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leptin, ghrelin and high-molecular-weight adiponectin in relation to anxiety in older adults","authors":"Merel van Andel ,&nbsp;Natasja M. van Schoor ,&nbsp;Nicole C. Korten ,&nbsp;Annemieke C. Heijboer ,&nbsp;Madeleine L. Drent","doi":"10.1016/j.psyneuen.2024.107190","DOIUrl":"10.1016/j.psyneuen.2024.107190","url":null,"abstract":"<div><h3>Background</h3><p>Leptin and ghrelin have been linked to depressive symptoms in older adults. There is a large overlap between depression and anxiety in this group. It is unclear whether the same associations exist with anxiety. Adiponectin has an inverse association with anxiety in older adults. However, the association between the most biologically active isoform - high-molecular-weight (HMW) adiponectin - and anxiety has not been previously reported.</p></div><div><h3>Methods</h3><p>We analyzed the association between leptin, ghrelin and HMW adiponectin and general symptoms of anxiety (HADS-A score ≥ 7) at baseline and after three years of follow-up in a population based cohort of older adults in the Netherlands (n = 898) using multivariable logistic regression analyses.</p></div><div><h3>Results</h3><p>For leptin there was significant effect modification by sex. We found a positive association between leptin and general symptoms of anxiety in men at baseline and after three years of follow-up after adjusting for depressive symptoms, when comparing the third to the first leptin tertile (T3 vs T1 OR 3.40, 95 % CI 1.08 – 10.78).</p><p>We found no significant associations for ghrelin.</p><p>HMW adiponectin was associated with general symptoms of anxiety at follow up. We found a positive association both before and after adjustment for depressive symptoms (T3 vs T1 OR 3.26, 95 % CI 1.36 – 7.83).</p></div><div><h3>Conclusions</h3><p>Our results showed significant associations in men only between leptin and HMW adiponectin and general symptoms of anxiety after three years of follow up. Our findings contribute to further insight into the pathophysiology of anxiety in older adults. However, further research is necessary as we show associations.</p></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S030645302400235X/pdfft?md5=ac342c14816a6e2a64b9aaaa98dde914&pid=1-s2.0-S030645302400235X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142274164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute immune system activation exerts time-dependent effects on inhibitory control: Results of both a randomized controlled experiment of influenza vaccination and a systematic review and meta-analysis – ISPNE 2024 Dirk Hellhammer Award","authors":"Grant S. Shields,&nbsp;Colton L. Hunter,&nbsp;Zach Buckner ,&nbsp;Mikayla D.M. Tolliver,&nbsp;Anastasia Makhanova","doi":"10.1016/j.psyneuen.2024.107186","DOIUrl":"10.1016/j.psyneuen.2024.107186","url":null,"abstract":"<div><div>Although coming down with an illness or receiving a vaccine are both common experiences, the influence of such acute immune system activations on cognitive processes, such as inhibitory control, has received relatively little attention. We addressed that issue by assessing the effects of acute immune system activation on inhibitory control in a randomized controlled experiment, and by conducting a meta-analysis of similar studies in humans. In our experiment, we found—somewhat surprisingly—that influenza vaccination improved performance on both of our inhibitory control outcomes (i.e., stop-signal reaction times and flanker interference effects). At the meta-analytic level, we found that at a short delay (1.5–4 hours post-injection) between immune activation and inhibitory control assessment, such activation impaired multiple forms of inhibitory control, whereas after a longer delay (e.g., &gt; 18 hours post-injection), such activation improved inhibitory control—consistent with our experiment. Moreover, proinflammatory cytokine activity predicted poorer interference control but better response inhibition, even with a long delay between injection and testing. Together, these results highlight nuanced, time-dependent, and—perhaps—multiple-mechanism-driven effects of acute immune system activity on inhibitory control.</div></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142473261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammation proteomic profiling of psychosis in young adults: Findings from the ALSPAC birth cohort","authors":"Ruby S.M. Tsang ,&nbsp;Nicholas J. Timpson ,&nbsp;Golam M. Khandaker","doi":"10.1016/j.psyneuen.2024.107188","DOIUrl":"10.1016/j.psyneuen.2024.107188","url":null,"abstract":"<div><div>Psychotic disorder is associated with altered levels of various inflammatory markers in blood, but existing studies have typically focused on a few selected biomarkers, have not examined specific symptom domains notably negative symptoms, and are based on individuals with established/chronic illness. Based on data from young people aged 24 years from the Avon Longitudinal Study of Parents and Children (ALSPAC), a UK birth cohort, we have examined the associations of 67 plasma immune/inflammatory proteins assayed using the Olink Target 96 Inflammation panel with psychotic disorder, positive (any psychotic experiences and definite psychotic experiences) and negative symptoms, using linear models with empirical Bayes estimation. The analyses included between 2317 and 2854 individuals. After adjustment for age, sex, body mass index and smoking and correction for multiple testing, positive symptoms and psychotic disorder were consistently associated with upregulation of CDCP1 and IL-6, and psychotic disorder was additionally associated with upregulation of MMP-10. Negative symptoms were associated with upregulation of CDCP1 and TRAIL. CDCP1 and MMP-10 are novel markers of psychosis identified in this study, and are involved in immune regulation, immune cell activation/migration, blood-brain barrier disruption, and extracellular matrix abnormalities. Our findings highlight psychosis symptom domains have overlapping and distinct immune associations, and support a role of inflammation and immune dysfunction in the pathogenesis of psychosis.</div></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142506746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between adolescent perceived loneliness and hair cortisol concentration","authors":"Avery M. Anderson ,&nbsp;Jessica Sherman ,&nbsp;Margaret M. Fitzpatrick ,&nbsp;Christopher Browning ,&nbsp;Darlene A. Kertes ,&nbsp;Amy Mackos ,&nbsp;Rita H. Pickler ,&nbsp;Lindsay Smith ,&nbsp;Jodi L. Ford","doi":"10.1016/j.psyneuen.2024.107184","DOIUrl":"10.1016/j.psyneuen.2024.107184","url":null,"abstract":"<div><h3>Introduction</h3><div>Adolescents experience high levels of loneliness, which is linked to poor health in adulthood. Loneliness may contribute to poor health through chronic dysregulation of the hypothalamic-pituitary-adrenal axis. In this analysis, we examined the associations between survey- and ecological momentary assessment (EMA)-based measures of loneliness and hair cortisol concentrations (HCC) in a sample of 1102 adolescents and assessed sex differences in this relationship.</div></div><div><h3>Methods</h3><div>Data came from wave 1 of the Adolescent Health and Development in Context study. We conducted a series of multivariable linear regression models to examine the associations between loneliness and HCC. Models were adjusted for adolescent and caregiver demographics, adolescent clinical factors, adolescent hair care practices, and adolescent lifetime mental health diagnosis and current psychotropic medication use. An interaction term between sex and loneliness was added to assess for effect moderation.</div></div><div><h3>Results</h3><div>In our sample, the mean HCC was 1.35 pg/mg (SD=1.1). The mean for the <em>unstandardized</em> survey loneliness measure was 1.79 (<em>SD</em>=0.79) for the total analytic sample. The <em>unstandardized</em> mean for the EMA loneliness measure was - 0.02 (<em>SD</em>=2.1) for the total analytic sample. In model one testing the bivariate linear relationship between loneliness and HCC, higher loneliness via survey and EMA measures was associated with lower HCC (<em>Survey</em>: <em>b</em>= - 0.10, SE=0.03, <em>p</em>=.004; <em>EMA</em>: <em>b</em>= - 0.09, SE=0.03, <em>p</em>=.005). In model two, higher loneliness remained significantly associated with lower HCC (<em>Survey</em>: <em>b</em>= - 0.07, SE=0.03, <em>p</em>=.023; <em>EMA</em>: <em>b</em>= - 0.07, SE=0.03, <em>p</em>=.037), after controlling for the following covariates: sociodemographic factors, pubertal development and BMI, corticosteroid use, hair care practices, season of collection and assayed hair length. In model 3, youth lifetime mental health diagnosis and current psychotropic medication use were added into the regression model, and higher loneliness remained significantly associated with lower HCC (<em>Survey</em>: <em>b</em>= - 0.07, SE=0.03, <em>p</em>=.029; <em>EMA</em>: <em>b</em>= - 0.07, SE=0.03, <em>p</em>=.039). There was no effect modification by sex (<em>Survey</em>: <em>b</em>=0.04, SE=0.06, <em>p</em>=.552; <em>EMA</em>: <em>b</em>= - 0.01, SE=0.06, <em>p</em>=.843).</div></div><div><h3>Conclusions</h3><div>In our analysis, both survey- and EMA-reported loneliness measures were associated with lower HCC. No evidence of an interaction between sex and loneliness was observed. Future research is needed to validate these findings and investigate longitudinal relationships among adolescent loneliness, stress physiology, and downstream health sequelae.</div></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142324198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early-life adversity severity, timing, and context type are associated with SLC6A4 methylation in emerging adults: Results from a prospective cohort study","authors":"Stephanie M. Koning ,&nbsp;Courtenay L. Kessler ,&nbsp;Turhan Canli ,&nbsp;Elif A. Duman ,&nbsp;Emma K. Adam ,&nbsp;Richard Zinbarg ,&nbsp;Michelle G. Craske ,&nbsp;Jacquelyn E. Stephens ,&nbsp;Suzanne Vrshek-Schallhorn","doi":"10.1016/j.psyneuen.2024.107181","DOIUrl":"10.1016/j.psyneuen.2024.107181","url":null,"abstract":"<div><h3>Background</h3><p>Epigenetic modifications, including DNA methylation (DNAm), can play a role in the biological embedding of early-life adversity (ELA) through serotonergic mechanisms. The current study examines methylation of the CpG island in the promoter region of the stress-responsive serotonin transporter gene (<em>SLC6A4</em>) and is the first to jointly assess how it is influenced by ELA severity, timing, and type—specifically, deprivation and threat.</p></div><div><h3>Methods</h3><p>We use data from 627 Youth Emotion Project study participants, recruited from two US high schools. Using adjusted linear regressions, we analyze DNA collected in early adulthood from 410 participants and ELA based on interviewer-rated responses from concurrent Childhood Trauma Interviews, adjusting for survey-measured covariates.</p></div><div><h3>Results</h3><p>ELA robustly predicted mean CpG island <em>SLC6A4</em> DNAm percent across 71 CpG sites. Each additional major-severity ELA event was associated with a 0.121-percentage-point increase (<em>p</em>&lt;0.001), equating to a 0.177 standard deviation (sd) higher DNAm level (95 % CI: 0.080, 0.274) with each 1-sd higher adversity score. When modeled separately, both childhood and adolescent ELA predicted <em>SLC6A4</em> DNAm. When modeled jointly, adolescent ELA was most strongly predictive, and child adversity remained significantly associated with DNAm through indirect associations via adolescent adversity. Additionally, the ELA-<em>SLC6A4</em> DNAm association may vary by adversity type. Across separate models for childhood and adolescent exposures, deprivation coefficients are positive and statistically significant. Meanwhile, threat coefficients are positive and not significantly significant but do not statistically differ from deprivation coefficients. In models including all ELA dimensions, one major adolescent deprivation event is associated with a 0.222-percentage-point increased <em>SLC6A4</em> DNAm (<em>p</em>&lt;0.05), or a 1-sd higher deprivation score with a 0.157-sd increased DNAm.</p></div><div><h3>Conclusion</h3><p>Results further implicate epigenetic modification on serotonergic neurotransmission via DNAm in the downstream sequelae of ELA—particularly adolescent deprivation—and support preventive interventions in adolescence to mitigate biological embedding.</p></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142243456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypothalamic-pituitary-adrenal axis function in the offspring of parents with bipolar disorder and the impact of the family environment: A pilot study of the Reducing Unwanted Stress in the Home (RUSH) prevention program","authors":"Erin Yong Ping,&nbsp;Heather Herriot,&nbsp;Vanessa Iacono,&nbsp;Lisa Serravalle,&nbsp;Mark A. Ellenbogen","doi":"10.1016/j.psyneuen.2024.107182","DOIUrl":"10.1016/j.psyneuen.2024.107182","url":null,"abstract":"<div><h3>Background</h3><div>The home environment of offspring of parents with bipolar disorder (OBD) has been characterized by high levels of stress and disorganization, which may impact development of the hypothalamic-pituitary-adrenal (HPA) axis and their subsequent risk for affective disorders. The present study examined the effects of a family-based preventative intervention on the OBD’s HPA axis functioning and whether intervention-related changes in the home environment might have driven change in the HPA axis.</div></div><div><h3>Methods</h3><div>Fifty-five children (6–11 years) were recruited from families having a parent with bipolar disorder (n=26) or families having two parents with no current mental disorders (n=29). Only those families with a parent having bipolar disorder participated in the preventative intervention. Both groups completed assessments at baseline, post-prevention, 3-, and 6-months post-prevention. At each assessment, family organization, control, cohesion, conflict, and expressiveness, in addition to childhood internalizing problems, were measured, and offspring saliva samples were collected across two consecutive days.</div></div><div><h3>Results</h3><div>Hierarchical Linear Modelling found no significant differences in HPA axis functioning between groups at baseline or across time. Improvements in family organization, however, were associated with elevations in participants’ cortisol awakening response (CAR; <em>p</em> =.004) and total daily output (<em>p</em> =.023), and a steepening of their diurnal slope (<em>p</em> =.003) across time. Similar findings were obtained for family cohesion with respect to CAR (<em>p</em> &lt;.001) and, to a lesser degree, diurnal slope (<em>p</em> =.064).</div></div><div><h3>Discussion</h3><div>HPA axis functioning did not differ between the OBD and healthy controls at baseline or in response to the preventative intervention. However, intervention-related improvements in family organization and, to a lesser degree, cohesion, were associated with adaptive changes in HPA functioning over time.</div></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing within-person variance in, and menstrual cycle associations with, event-related potentials associated with positive and negative valence systems: The reward positivity and the error-related negativity","authors":"Elizabeth M. Mulligan ,&nbsp;Tory A. Eisenlohr-Moul ,&nbsp;Anisha Nagpal ,&nbsp;Katja M. Schmalenberger ,&nbsp;Lisa Eckel ,&nbsp;Greg Hajcak","doi":"10.1016/j.psyneuen.2024.107183","DOIUrl":"10.1016/j.psyneuen.2024.107183","url":null,"abstract":"<div><p>Event-related potentials (ERPs) are widely employed as measures of transdiagnostic cognitive processes that are thought to underlie various clinical disorders (Hajcak et al., 2019). Despite their prevalent use as individual difference measures, the effects of within-person processes, such as the human menstrual cycle, on a broad range of ERPs are poorly understood. The present study leveraged a within-subject design to characterize between- and within-person variance in ERPs as well as effects of the menstrual cycle in two frequently studied ERPs associated with positive and negative valence systems underlying psychopathology—the Reward Positivity (RewP) and the Error- Related Negativity (ERN). Seventy-one naturally-cycling participants completed repeated EEG and ecological momentary assessments of positive and negative affect in the menstrual cycle's early follicular, periovulatory, and mid-luteal phases. We examined the mean degree of change between cycle phases in both ERPs, the between-person variability in the degree of change in both ERPs, and whether an individual’s degree of cyclical change in these ERPs show coherence with their degree of cyclical change in positive and negative affect recorded across the cycle. Results revealed no significant changes in positive and negative affect across the cycle and rather small changes in ERP amplitudes. Significant random slopes in our model revealed larger individual differences in trajectories of change in ERP amplitudes and affect, in agreement with prior evidence of heterogeneity in dimensional hormone sensitivity. Additionally, state-variance in these ERPs correlated with positive and negative affect changes across the cycle, suggesting that cycle-mediated ERP changes may have relevance for affect and behavior. Finally, exploratory latent class growth mixture modeling revealed subgroups of individuals that display disparate patterns of change in ERPs that should be further investigated.</p></div>","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142274163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of feminist science for social neuroendocrinology","authors":"Sari M. van Anders","doi":"10.1016/j.psyneuen.2024.107167","DOIUrl":"10.1016/j.psyneuen.2024.107167","url":null,"abstract":"","PeriodicalId":20836,"journal":{"name":"Psychoneuroendocrinology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142294015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}