Process Biochemistry最新文献_第2页

Protein hydrolysates from black soldier fly larvae (Hermetia illucens): Experimental design, ultrafiltration fractionation, and kinetics of bioactive peptide production 黑兵蝇幼虫（Hermetia illucens）蛋白质水解物：实验设计、超滤分离和生物活性肽生产动力学

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-04-01 Epub Date: 2026-02-09 DOI: 10.1016/j.procbio.2026.02.005

Yuri Matheus Silva Amaral , Leonardo Buzaneli Cristianini, Ruann Janser Soares de Castro

{"title":"Protein hydrolysates from black soldier fly larvae (Hermetia illucens): Experimental design, ultrafiltration fractionation, and kinetics of bioactive peptide production","authors":"Yuri Matheus Silva Amaral , Leonardo Buzaneli Cristianini, Ruann Janser Soares de Castro","doi":"10.1016/j.procbio.2026.02.005","DOIUrl":"10.1016/j.procbio.2026.02.005","url":null,"abstract":"<div><div>The improvement of the biological properties of insect proteins has been widely studied with a view to their inclusion in foods for humans and animals. The aim of this work was to study the production of bioactive peptides through enzymatic hydrolysis of proteins from black soldier fly larvae. For this purpose, an experimental mixture design was employed using the proteases Flavourzyme, Alcalase and Neutrase as factors, and antioxidant activity of the protein hydrolysates as the response of interest. The results revealed that the combination of Flavourzyme (2/3), Alcalase (1/6) and Neutrase (1/6) resulted in protein hydrolysates with the highest values of antioxidant activity, quantified by the ABTS (588.04 µmol TE/g), DPPH (30.15 µmol TE/g) and FRAP (76.29 µmol TE/g) methods. The kinetic study demonstrated that the proteases in combination maintained 80 % of the enzymatic activity through 180 min of hydrolysis. Furthermore, the hydrolysates were ultrafiltered and the peptides between 5 and 3 kDa showed greater antioxidant activity. According to data obtained from liquid chromatography-mass spectrometry (LC-MS/MS) and <em>in silico</em> analysis, the peptides YPGEL, AIGGW, LAWQF, and LGPPGAG showed the most promising antioxidant activity. The results obtained demonstrated the potential of enzymatic hydrolysis to selectively modify the proteins of black soldier fly larvae.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"163 ","pages":"Pages 77-86"},"PeriodicalIF":4.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146191856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyhydroxyalkanoate production: Surplus storage stimulating selective growth; feasible soap digestion for downstream recovery and characterization 聚羟基烷酸酯生产：剩余储存刺激选择性生长；可行的肥皂消化下游回收和表征

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-04-01 Epub Date: 2026-02-05 DOI: 10.1016/j.procbio.2026.02.004

Sydney T-Thy Nguyen-Huynh , Li Wan Yoon , Adeline Seak May Chua , Yin Hui Chow

{"title":"Polyhydroxyalkanoate production: Surplus storage stimulating selective growth; feasible soap digestion for downstream recovery and characterization","authors":"Sydney T-Thy Nguyen-Huynh , Li Wan Yoon , Adeline Seak May Chua , Yin Hui Chow","doi":"10.1016/j.procbio.2026.02.004","DOIUrl":"10.1016/j.procbio.2026.02.004","url":null,"abstract":"<div><div>Process enhancement for microbial PHA production by mixed cultures is still limited in approaching the industrial scale, which expects better performance in terms of PHA volumetric productivity (Q<sub>vol</sub>) and sustainable PHA recovery. This study investigated feasibility of pulse feeding (PF) mode for PHA accumulation, soap digestion and characterization. The store-grow relationship in mixed cultures highlighted importance of PHB surplus storage (supply-dependence but no competition with other metabolic activities) in stimulating the selective growth of PHB storing bacteria. PF mode (3233 mg glycerol/pulse) significantly improved Q<sub>vol</sub> to 246 mg/(L.h) with lowered PHB content in biomass to 62 % due to effective mobilization of stored PHB. When reducing dosage per pulse by half, PHB content maximized at 98 % was compromised by a slight decrease in Q<sub>vol.</sub> to 209 mg/(L.h). With approximately 90 % PHB yield and purity, the alternative soap digestion was highly comparable to the halogenated solvent extraction. However, PHB degradation constituted to 17 % PHB loss, low Mw at nearly 900 Da, T<sub>m</sub> of 89–133℃ and crystallization of 50–123 %, affecting PHB quality. The PHB bioplastic product was characterized for their thermal and mechanical properties. This study demonstrated the feasible PHB process configuration, i.e., culture enrichment by coupled feeding, PHB accumulation under PF mode in the upstream followed by soap digestion in downstream recovery.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"163 ","pages":"Pages 42-57"},"PeriodicalIF":4.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146191857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solid-state fermentation of Daldinia eschscholtzii ZZNS-Y2, an approach to produce jasminodiol by Gardenia jasminoides-derived fungus 栀子属真菌固态发酵制备栀子二醇的研究

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-04-01 Epub Date: 2026-02-11 DOI: 10.1016/j.procbio.2026.02.015

Jian-Wei Dong , Xiao-Xin Xu , Xue-Jiao Li , Liang Deng , Xiao-Yan Wang , Meng-yao Lv

{"title":"Solid-state fermentation of Daldinia eschscholtzii ZZNS-Y2, an approach to produce jasminodiol by Gardenia jasminoides-derived fungus","authors":"Jian-Wei Dong , Xiao-Xin Xu , Xue-Jiao Li , Liang Deng , Xiao-Yan Wang , Meng-yao Lv","doi":"10.1016/j.procbio.2026.02.015","DOIUrl":"10.1016/j.procbio.2026.02.015","url":null,"abstract":"<div><div>Jasminodiol, an iridoid (monoterpenoid) compound isolated from the fruit of <em>Gardenia jasminoides</em>, has been reported to exhibit potent antityrosinase and anxiolytic activities. Currently, it is obtained exclusively through extraction from plant sources, with no microbial fermentation route established to date. This study aims to produce iridoids via endophytic fungi isolated from <em>G. jasminoides</em>. As a result, jasminodiol was successfully obtained from the solid-state fermentation (SSF) products of <em>Daldinia eschscholtzii</em> ZZNS-Y2, an endophytic fungus derived from <em>G. jasminoides</em>. The chemical structure of jasminodiol was elucidated based on spectroscopic data from <sup>1</sup>H and <sup>13</sup>C NMR analyses. Furthermore, key fermentation parameters including substrate type, temperature, and fermentation time, were investigated. The high yield of jasminodiol (6.72 ± 0.20 mg/g) was achieved when SSF was conducted using corn niblet as the substrate at 28 °C for 40 d. This is the first report on the production of jasminodiol using microorganisms rather than plant extraction.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"163 ","pages":"Pages 122-126"},"PeriodicalIF":4.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146192411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced denitrification in microbial electrolysis cells by employing riboflavin and reduced graphene oxide modified cathodes 利用核黄素和还原氧化石墨烯修饰阴极增强微生物电解细胞的反硝化作用

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-04-01 Epub Date: 2026-02-03 DOI: 10.1016/j.procbio.2026.02.001

Xiang Li , Tingting Zhao , Xiaomin Hu , Xinyue Wang , Zhengdong Liu , Haimeng Hou

{"title":"Enhanced denitrification in microbial electrolysis cells by employing riboflavin and reduced graphene oxide modified cathodes","authors":"Xiang Li , Tingting Zhao , Xiaomin Hu , Xinyue Wang , Zhengdong Liu , Haimeng Hou","doi":"10.1016/j.procbio.2026.02.001","DOIUrl":"10.1016/j.procbio.2026.02.001","url":null,"abstract":"<div><div>Nitrate pollution poses a significant threat to aquatic ecosystems and public health due to its high solubility and mobility in groundwater. Microbial electrolysis cells (MECs) offer a promising approach for nitrate removal from water; however, their denitrification efficiency remains limited. A composite cathode consisting of reduced graphene oxide-modified carbon cloth further electrodeposited with riboflavin (RF/rGO/CC) was employed in MECs to enhance denitrification performance. Over a 10-day operational period, the residual nitrate concentration in the catholyte of the RF/rGO/CC group decreased to 34.48 % of the initial level, compared with 54.33 % in the unmodified carbon cloth group. Scanning electron microscopy and confocal laser scanning microscopy revealed significantly increased biofilm density and microbial viability on the modified cathode. Electrochemical analyses confirmed that the RF/rGO/CC electrode exhibited superior electrochemical activity, which was reflected by a higher nitrate reduction peak observed in CV and a lower charge transfer resistance revealed by EIS. Moreover, the modified cathode enriched electroactive denitrifying bacteria and significantly increased the abundances of key functional genes involved in the denitrification pathway, including <em>napA</em>, <em>narG</em>, <em>nirK</em>, <em>nirS</em>, and <em>nosZ</em>. This study presents a promising strategy for enhancing nitrate removal efficiency in bioelectrochemical systems through cathode surface modification.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"163 ","pages":"Pages 32-41"},"PeriodicalIF":4.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146191854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heterologous expression of phospholipase A1 in Streptomyces mobaraensis and its application in crude oil degumming 磷脂酶A1在莫巴拉链霉菌中的异源表达及其在原油脱胶中的应用

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-04-01 Epub Date: 2026-02-12 DOI: 10.1016/j.procbio.2026.02.009

Hongjian Xue , Jingwen Zhou , Guocheng Du , Song Liu

{"title":"Heterologous expression of phospholipase A1 in Streptomyces mobaraensis and its application in crude oil degumming","authors":"Hongjian Xue , Jingwen Zhou , Guocheng Du , Song Liu","doi":"10.1016/j.procbio.2026.02.009","DOIUrl":"10.1016/j.procbio.2026.02.009","url":null,"abstract":"<div><div>Phospholipase A1 (PLA1) selectively hydrolyzes the <em>sn-1</em> ester of phospholipids and is ideal for enzymatic oil degumming. To efficiently produce PLA1, this study heterologously expressed the saPLA1 gene from <em>Streptomyces albidoflavus</em> NA297 in the genome-reduced strain <em>Streptomyces mobaraensis</em> smYS1-Δ<em>tg</em>, and analyzed the enzymatic properties and degumming performance of the recombinant enzyme. Results showed that under the control of the strong promoter P<em>gapdh</em> and the transglutaminase (TGase) signal peptide, secretory activity peaked at 39.4 U/mL within 48 h. It exhibited optimal activity at 50°C and pH 6.0, with good stability over pH 5–8. Additionally, saPLA1 was significantly activated by Mn<sup>2 +</sup> , Fe<sup>2+</sup> and citrate, and functioned in a Ca<sup>2+</sup>-independent manner. Under optimized process conditions, saPLA1 reduced the phosphorus content in crude soybean oil from 113.01 to 7.27 mg/kg within 2.5 h, meeting the physical refining requirement. This study provides a novel strategy for the industrial production and application of food-grade saPLA1.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"163 ","pages":"Pages 114-121"},"PeriodicalIF":4.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146192410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An enzymatic approach for producing chitin from snow crab and American lobster seashells 用酶法从雪蟹和美洲龙虾贝壳中制备几丁质

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-03-01 Epub Date: 2025-12-25 DOI: 10.1016/j.procbio.2025.12.015

Pauline Potier, Gabriela Vollet Marson, Ariane Tremblay, Alain Doyen, Lucie Beaulieu

{"title":"An enzymatic approach for producing chitin from snow crab and American lobster seashells","authors":"Pauline Potier, Gabriela Vollet Marson, Ariane Tremblay, Alain Doyen, Lucie Beaulieu","doi":"10.1016/j.procbio.2025.12.015","DOIUrl":"10.1016/j.procbio.2025.12.015","url":null,"abstract":"<div><div>Shellfish processing plants generate large volumes of by-products rich in high-value biomolecules such as proteins, minerals, and chitin. Currently, chitin extraction is mainly carried out by chemical hydrolysis using strong acids and bases, a method with a large environmental impact. To address these concerns, a sustainable enzymatic approach was developed for extracting chitin from snow crab and American lobster shells. Different acid-active proteases were tested to identify the most effective enzyme for simultaneous deproteinization and demineralization of the shells. Pepsin demonstrated the highest efficiency, achieving over 95 % demineralization and 78 % deproteinization. The process was further optimized to minimize enzyme concentration and hydrolysis time. The respective optimum parameters for crab and lobster were 3130 and 2070 U of pepsin per gram of protein for 2.5 h. In these conditions, deproteinization rates of 74.0 % and 81.1 % and demineralization rates of 94.5 % and 90.8 % were achieved for crab and lobster shells, respectively. Additionally, soluble proteins from the enzymatic hydrolysis were recovered and characterized, demonstrating their potential for use in animal feed and for bioactive peptides production.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"162 ","pages":"Pages 7-15"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revealing and manipulating the LmbU-mediated connection between lincomycin production and the ectABCD gene cluster in S. lincolnensis 揭示和操纵lmbu介导的林肯葡萄球菌林可霉素生产与ectABCD基因簇之间的联系

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.procbio.2026.01.002

Yue Mao , Jiang Ye , Ruida Wang , Haizhen Wu , Huizhan Zhang

{"title":"Revealing and manipulating the LmbU-mediated connection between lincomycin production and the ectABCD gene cluster in S. lincolnensis","authors":"Yue Mao , Jiang Ye , Ruida Wang , Haizhen Wu , Huizhan Zhang","doi":"10.1016/j.procbio.2026.01.002","DOIUrl":"10.1016/j.procbio.2026.01.002","url":null,"abstract":"<div><div>Lincomycin, an antibiotic produced by <em>Streptomyces lincolnensis</em>, is widely used to treat Gram-positive bacterial and anaerobic infections. This study found that LmbU, a positive regulatory factor within the lincomycin biosynthesis gene cluster, can positively regulate the extracellular target gene cluster <em>ectABCD</em> (<em>ect</em>), which is involved in the synthesis of ectoine/hydroxyectoine. By knocking out <em>ect</em>, the lincomycin production was increased 2.8-fold. The addition of exogenous <span>L</span>-Asp in both xbl1 and Δ<em>ect</em> strains confirmed that the increased lincomycin production in Δ<em>ect</em> was due to enhanced precursor supply. Furthermore, osmotic stress experiments demonstrated that moderate NaCl concentrations could increase both <em>ect</em> expression and lincomycin production, while higher osmotic pressures resulted in decreased production and biomass. Together, these findings provide new mechanistic insights and offer a theoretical basis for the rational design of high-production industrial strains.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"162 ","pages":"Pages 16-23"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145929037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasonic-alkaline-thermal pretreatment on cassava sago waste for the energy efficient biomethane production 超声波-碱-热预处理木薯西米废渣的高效生物甲烷生产

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-03-01 Epub Date: 2026-01-28 DOI: 10.1016/j.procbio.2026.01.018

Preethi, Harshitha Nainar, V. Karunya, G. Neha, R. Preetha, Rajeev Kumar Bhaskar, P. Rajaguru, J. Rajesh Banu

{"title":"Ultrasonic-alkaline-thermal pretreatment on cassava sago waste for the energy efficient biomethane production","authors":"Preethi, Harshitha Nainar, V. Karunya, G. Neha, R. Preetha, Rajeev Kumar Bhaskar, P. Rajaguru, J. Rajesh Banu","doi":"10.1016/j.procbio.2026.01.018","DOIUrl":"10.1016/j.procbio.2026.01.018","url":null,"abstract":"<div><div>Globally, cassava tuber is considered a staple food in many developing countries, and it is processed to extract starch from the tubers. Industrial production of sago from cassava tuber generates a considerable quantity of waste with high organic content. However, its intricate structure limits hydrolysis, the first step during bioenergy production. In this study, ultrasonic pretreatment and combinations of ultrasonic-alkali or ultrasonic-alkali-thermal pretreatment were tried to improve hydrolysis. Ultrasonic pretreatment of sago industrial waste (SIW) resulted in 1.53 % solubilization at 140 W ultrasonic power. While the combination of alkali (pH 11) with ultrasonic power of 140 W resulted in a mild increment in solubilization to 2 %. The introduction of thermal treatment with ultrasonic alkali pretreatment caused a drastic improvement in COD solubilization to 29.6 % at 80°C. Improvement in COD solubilization subsequently resulted in greater biomethane generation (303.4 mL/g VS<sub>consumed</sub>) for ultrasonic-alkaline-thermal pretreatment compared to others. Similarly, the energy analysis shows a positive net energy of 109.55 kWh and an energy ratio of 1.54. Hence, the proposed combination is scalable for industrial biomethane production.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"162 ","pages":"Pages 183-190"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of variable aeration on partial nitritation/anammox (PN/A): Insights from batch testing and microbial analysis 可变曝气对部分硝化/厌氧氨氧化（PN/A）的影响：来自批量试验和微生物分析的见解

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-03-01 Epub Date: 2026-01-14 DOI: 10.1016/j.procbio.2026.01.007

Weronika Borowska , Martyna Godzieba , Slawomir Ciesielski , Monika Zubrowska-Sudol

{"title":"Impact of variable aeration on partial nitritation/anammox (PN/A): Insights from batch testing and microbial analysis","authors":"Weronika Borowska , Martyna Godzieba , Slawomir Ciesielski , Monika Zubrowska-Sudol","doi":"10.1016/j.procbio.2026.01.007","DOIUrl":"10.1016/j.procbio.2026.01.007","url":null,"abstract":"<div><div>This study explores the influence of variable aeration strategies on microbial interactions within the partial nitritation/anammox (PN/A) process. To overcome the limitations of relying solely on microbial abundance, this research integrates high-throughput DNA sequencing, reverse transcription-quantitative polymerase chain reaction (RT-qPCR), and batch tests to link microbial function and adaptation to variable aeration strategies. Four operational stages were investigated: continuous aeration with a dissolved oxygen (DO) concentration of 1.5 mg O₂/L; intermittent aeration at a ratio of 1:2 with the same DO; increased DO to 2.5 mg O₂/L while maintaining the intermittent regime; and equal duration of aerated and non-aerated phases (1:1) with DO at 2.5 mg O₂/L. Among these, the third stage intermittent aeration at 2.5 mg O₂/L proved to be the most favorable for the PN/A process, yielding the highest anammox activity and effective suppression of nitrite-oxidizing bacteria. Results show that the rate of nitrogen conversion is related to the particular structure of microbial communities, as revealed by network analysis. Importantly, even low-abundance functional groups contributed significantly to nitrogen removal under favorable environmental conditions. The combined methodological approach allowed for an effective correlation between microbial structure and activity, offering a valuable framework for interpreting microbial responses to operational changes.</div></div>","PeriodicalId":20811,"journal":{"name":"Process Biochemistry","volume":"162 ","pages":"Pages 62-73"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145980658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitigation of antibiotic-resistant bacteria isolated from hospital effluent by lytic bacteriophage infection 通过溶解噬菌体感染减少医院流出物中分离的耐药细菌

IF 4 3区生物学

Process Biochemistry Pub Date : 2026-03-01 Epub Date: 2026-01-09 DOI: 10.1016/j.procbio.2026.01.001

Hayeon Lee, Jeongdong Choi

引用次数: 0