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QJM: An International Journal of Medicine最新文献

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Hypertrophic inferior olivary nucleus degeneration and peri-dentate hyperintensities in POLG mutation. 增生性下橄榄核变性和周围齿状高强度POLG突变。
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf020
Alvee Saluja, Samrin Haq, Pratik Karak, Sayani Mahal
{"title":"Hypertrophic inferior olivary nucleus degeneration and peri-dentate hyperintensities in POLG mutation.","authors":"Alvee Saluja, Samrin Haq, Pratik Karak, Sayani Mahal","doi":"10.1093/qjmed/hcaf020","DOIUrl":"10.1093/qjmed/hcaf020","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"536-537"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Other potential beneficiaries of disease-modifying strategies. 疾病改变策略的其他潜在受益者。
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf076
Oscar M P Jolobe
{"title":"Other potential beneficiaries of disease-modifying strategies.","authors":"Oscar M P Jolobe","doi":"10.1093/qjmed/hcaf076","DOIUrl":"10.1093/qjmed/hcaf076","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"551-552"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent basal ganglia stroke due to mineralizing lenticulostriate vasculopathy. 矿化透镜状纹状体血管病变引起的复发性基底神经节中风。
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf009
Singanamalla Bhanudeep, Bramhini Bhargavi Koneti
{"title":"Recurrent basal ganglia stroke due to mineralizing lenticulostriate vasculopathy.","authors":"Singanamalla Bhanudeep, Bramhini Bhargavi Koneti","doi":"10.1093/qjmed/hcaf009","DOIUrl":"10.1093/qjmed/hcaf009","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"526-527"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142953994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seizure clusters with typical 'evolution' in EEG. 脑电图具有典型的“进化”特征。
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf014
Miharuka Yokosaki, Shuichiro Neshige, Naoki Takahashi, Shiro Aoki, Hirofumi Maruyama
{"title":"Seizure clusters with typical 'evolution' in EEG.","authors":"Miharuka Yokosaki, Shuichiro Neshige, Naoki Takahashi, Shiro Aoki, Hirofumi Maruyama","doi":"10.1093/qjmed/hcaf014","DOIUrl":"10.1093/qjmed/hcaf014","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"530-531"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Air pollution and colorectal cancer risk. 空气污染与结直肠癌风险
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf171
Seamas C Donnelly
{"title":"Air pollution and colorectal cancer risk.","authors":"Seamas C Donnelly","doi":"10.1093/qjmed/hcaf171","DOIUrl":"https://doi.org/10.1093/qjmed/hcaf171","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":"118 7","pages":"475"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A call for rigorous research investment in women's health. 呼吁对妇女健康进行严格的研究投资。
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcae225
Zhaohui Su, Ruijie Zhang, Francis Mungai Kaburu, Chaojun Tong, Mehak Intizar, Abdulswabul Kudiza, Qiang Kuang, Ruru Chen, Xin Yu, Jianlin Jiang, Dean McDonnell, Ali Cheshmehzangi, Sabina Šegalo, Junaid Ahmad, Claudimar Pereira da Veiga, Yu-Tao Xiang
{"title":"A call for rigorous research investment in women's health.","authors":"Zhaohui Su, Ruijie Zhang, Francis Mungai Kaburu, Chaojun Tong, Mehak Intizar, Abdulswabul Kudiza, Qiang Kuang, Ruru Chen, Xin Yu, Jianlin Jiang, Dean McDonnell, Ali Cheshmehzangi, Sabina Šegalo, Junaid Ahmad, Claudimar Pereira da Veiga, Yu-Tao Xiang","doi":"10.1093/qjmed/hcae225","DOIUrl":"10.1093/qjmed/hcae225","url":null,"abstract":"<p><p>Worldwide, women face a disproportionately heavier health burden than their male counterparts. Yet, there is a chronic lack of research attention and investment in women's health, which may explain the absence of women-inclusive, let alone women-centered, understanding of the causes, consequences and confounding factors that shape individuals' health and quality of life. In this article, by analyzing the US National Health Expenditure data, we show how ingrained the issue of poor investment in women's health even in the 0-18 years age group in terms of per capita health expenditure. We hope this article sheds light on how early-life poor health investment in women's health might be a potential cause for women's poor health in adulthood, and in turn, underscores the importance of investing resources into better understanding and improving women's health.</p>","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"477-478"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reactivation of latent syphilis during immunosuppressive therapy in SLE. SLE免疫抑制治疗期间潜伏梅毒的再激活。
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf019
Chuan-Peng Wang, Jia Zhou, Jun Li
{"title":"Reactivation of latent syphilis during immunosuppressive therapy in SLE.","authors":"Chuan-Peng Wang, Jia Zhou, Jun Li","doi":"10.1093/qjmed/hcaf019","DOIUrl":"10.1093/qjmed/hcaf019","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"534-535"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel model for identifying infections in patients with AoCLD: a nationwide, multicenter, prospective cohort study. 一种识别急性慢性肝病（AoCLD）患者感染的新模型：一项全国多中心前瞻性队列研究
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf052
Hui Zhou, Hai Li, Guohong Deng, Xianbo Wang, Xin Zheng, Jinjun Chen, Zhongji Meng, Yubao Zheng, Yanhang Gao, Zhiping Qian, Feng Liu, Xiaobo Lu, Yu Shi, Jia Shang, Yan Huang, Ruochan Chen
{"title":"A novel model for identifying infections in patients with AoCLD: a nationwide, multicenter, prospective cohort study.","authors":"Hui Zhou, Hai Li, Guohong Deng, Xianbo Wang, Xin Zheng, Jinjun Chen, Zhongji Meng, Yubao Zheng, Yanhang Gao, Zhiping Qian, Feng Liu, Xiaobo Lu, Yu Shi, Jia Shang, Yan Huang, Ruochan Chen","doi":"10.1093/qjmed/hcaf052","DOIUrl":"10.1093/qjmed/hcaf052","url":null,"abstract":"<p><strong>Background and aims: </strong>To establish an early and quick model for diagnosing infections in patients with acute-on-chronic liver disease (AoCLD).</p><p><strong>Approach: </strong>This study analysed 3949 patients from two multicenter prospective cohorts of the Chinese Acute-on-Chronic Liver Failure (CATCH-LIFE) study. The dataset was randomly divided into training and validation cohorts in a 7:3 ratio. In the training cohort, logistic regression and least absolute shrinkage and selection operator regression analyses were used to identify predictive risk factors for infection in patients with AoCLD, and a simple nomogram was established. Two different cutoff values were determined to stratify infection risk in AoCLD patients.</p><p><strong>Results: </strong>The developed diagnostic model included six variables: cirrhosis, ascites, neutrophil count (N), total bilirubin, C-reactive protein (CRP) and blood sodium levels. The area under the receiver operating characteristic curve for the training and validation cohorts was 0.818 and 0.809, respectively, significantly higher than using CRP, procalcitonin or N alone. Additionally, in the training cohort, we set a low cutoff value of 0.2028, resulting in a sensitivity of 80.15%, specificity of 68.25% and a negative predictive value of 92.7% for rule-out diagnosis. A high cutoff value of 0.4045 results in a specificity of 90.1%, sensitivity of 52.7% and a positive predictive value of 64% for rule-in diagnosis. These cutoff values were validated in the validation cohort.</p><p><strong>Conclusions: </strong>We established a nomogram model to assist clinicians in diagnosing infections in patients with AoCLD, effectively improving the accuracy and timeliness of diagnosis.</p>","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"489-500"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Florid ascites associated with alcohol use disorder without cirrhosis. 水肿腹水与无肝硬化的酒精使用障碍相关。
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf069
Ami Schattner, Ina Dubin, Livnat Uliel
{"title":"Florid ascites associated with alcohol use disorder without cirrhosis.","authors":"Ami Schattner, Ina Dubin, Livnat Uliel","doi":"10.1093/qjmed/hcaf069","DOIUrl":"10.1093/qjmed/hcaf069","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"543-544"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive tourniquet test in dengue fever. 登革热病人止血带试验呈阳性。
IF 6.4 4区 医学
QJM: An International Journal of Medicine Pub Date : 2025-07-01 DOI: 10.1093/qjmed/hcaf004
Yumi Kawamura, Kiyoshi Shikino, Takushi Fujimoto
{"title":"Positive tourniquet test in dengue fever.","authors":"Yumi Kawamura, Kiyoshi Shikino, Takushi Fujimoto","doi":"10.1093/qjmed/hcaf004","DOIUrl":"10.1093/qjmed/hcaf004","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":"525"},"PeriodicalIF":6.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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