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QJM: An International Journal of Medicine最新文献

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Transient Right Bundle Branch Block and S1Q3T3 Pattern in Acute Pulmonary Embolism. 急性肺栓塞中一过性右束支阻滞和S1Q3T3模式。
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-07 DOI: 10.1093/qjmed/hcag282
Ra'ed Ababneh, Emad Algorani, Laith Rhabneh, Shahd Qaddour, Jamil Wafi, Ala'a Al-Deen Mousa, Mohammed Alkhanafsa
{"title":"Transient Right Bundle Branch Block and S1Q3T3 Pattern in Acute Pulmonary Embolism.","authors":"Ra'ed Ababneh, Emad Algorani, Laith Rhabneh, Shahd Qaddour, Jamil Wafi, Ala'a Al-Deen Mousa, Mohammed Alkhanafsa","doi":"10.1093/qjmed/hcag282","DOIUrl":"https://doi.org/10.1093/qjmed/hcag282","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symptom-days and symptomatic children: what does XLTG11 actually prevent? 症状日和症状儿童：XLTG11实际上预防了什么？
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-07 DOI: 10.1093/qjmed/hcag279
Nezihe Köker Özer, Ercan Yılmaz
{"title":"Symptom-days and symptomatic children: what does XLTG11 actually prevent?","authors":"Nezihe Köker Özer, Ercan Yılmaz","doi":"10.1093/qjmed/hcag279","DOIUrl":"https://doi.org/10.1093/qjmed/hcag279","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced occupational noise exposure and reduced telomere length with enhanced risk of heart disease: evidence from two populations. 职业性噪声暴露增加和端粒长度减少与心脏病风险增加：来自两个人群的证据
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-05 DOI: 10.1093/qjmed/hcag276
Yanhong Lai, Zhaomin Chen, Haozhe Zhang, Qiyou Tan, Kaiji Lang, Hong Zhang, Shuo Yang, Yuqin Liu, Weihong Chen, Wenzhen Li, Dongming Wang
{"title":"Enhanced occupational noise exposure and reduced telomere length with enhanced risk of heart disease: evidence from two populations.","authors":"Yanhong Lai, Zhaomin Chen, Haozhe Zhang, Qiyou Tan, Kaiji Lang, Hong Zhang, Shuo Yang, Yuqin Liu, Weihong Chen, Wenzhen Li, Dongming Wang","doi":"10.1093/qjmed/hcag276","DOIUrl":"https://doi.org/10.1093/qjmed/hcag276","url":null,"abstract":"<p><strong>Background: </strong>Occupational noise exposure has been linked to cardiovascular risk, but its associations with emerging lipid-related cardiovascular predictors and the potential role of leukocyte telomere length (LTL) remain unclear.</p><p><strong>Aim: </strong>This study aimed to investigate associations of occupational noise exposure with the atherogenic index of plasma (AIP) and the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR), and to explore the potential involvement of LTL.</p><p><strong>Design and methods: </strong>This cross-sectional study included 765 Chinese workers and 131,214 participants from the UK Biobank. In the occupational cohort, cumulative noise exposure (CNE) was calculated using occupational histories and workplace noise monitoring data. AIP and NHHR were derived from lipid biomarkers, and LTL was measured by qRT-PCR. Generalized linear models, restricted cubic splines, interaction analyses and mediation analyses were performed.</p><p><strong>Results: </strong>CNE was positively and nonlinearly associated with AIP and NHHR (both P for overall < 0.01 and P for nonlinear < 0.01); negatively associated with LTL (P for overall < 0.01 and P for nonlinear = 0.017). LTL was negatively associated with AIP (β: -0.008; 95% CI: -0.015, -0.002) and NHHR (β: -0.056; 95% CI: -0.078, -0.033). LTL explained the associations of noise level and CNE with NHHR, with the proportions of 16.51% and 34.90%, respectively. Similar associations of occupational noise exposure with AIP and LTL were observed in UKB.</p><p><strong>Conclusion: </strong>Our study demonstrates positive associations of occupational noise exposure with AIP and NHHR, and suggests that LTL plays an important role in those associations.</p>","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to: External Validity and Performance Metrics in a Metabolomics-Enhanced Prediction Model for Residual Pulmonary Vascular Obstruction. 响应：代谢组学增强残余肺血管阻塞预测模型的外部有效性和性能指标。
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-05 DOI: 10.1093/qjmed/hcag271
Xue Xu, Xiaoyu Cheng, Guiyin Zhu, Qiangqiang Qin, Wenjing Ye, Shili Chen, Lingwei Yu, Xiaoming Li, Wen Gu
{"title":"Response to: External Validity and Performance Metrics in a Metabolomics-Enhanced Prediction Model for Residual Pulmonary Vascular Obstruction.","authors":"Xue Xu, Xiaoyu Cheng, Guiyin Zhu, Qiangqiang Qin, Wenjing Ye, Shili Chen, Lingwei Yu, Xiaoming Li, Wen Gu","doi":"10.1093/qjmed/hcag271","DOIUrl":"https://doi.org/10.1093/qjmed/hcag271","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discordant numerator reporting for prior osteoporosis diagnosis and treatment in an opportunistic CTPA screening study. 在一项机会性CTPA筛查研究中，先前骨质疏松症诊断和治疗的分子报告不一致。
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-05 DOI: 10.1093/qjmed/hcag273
Hefziba Lorences Noguera, Esteban Cardenas-Duran, Carlos Alejandro Gomez Anguiano
{"title":"Discordant numerator reporting for prior osteoporosis diagnosis and treatment in an opportunistic CTPA screening study.","authors":"Hefziba Lorences Noguera, Esteban Cardenas-Duran, Carlos Alejandro Gomez Anguiano","doi":"10.1093/qjmed/hcag273","DOIUrl":"https://doi.org/10.1093/qjmed/hcag273","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Confounding by Indication and Outcome Ascertainment in the Reported Cardioprotective Effect of PCSK9 Inhibitors on Incident Heart Failure. 报道的PCSK9抑制剂对心力衰竭的心脏保护作用的适应症和结果确定的混淆。
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-05 DOI: 10.1093/qjmed/hcag277
Hefziba Lorences Noguera, Esteban Cárdenas-Durán
{"title":"Confounding by Indication and Outcome Ascertainment in the Reported Cardioprotective Effect of PCSK9 Inhibitors on Incident Heart Failure.","authors":"Hefziba Lorences Noguera, Esteban Cárdenas-Durán","doi":"10.1093/qjmed/hcag277","DOIUrl":"https://doi.org/10.1093/qjmed/hcag277","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
External Validity and Performance Metrics in a Metabolomics-Enhanced Prediction Model for Residual Pulmonary Vascular Obstruction. 残留肺血管阻塞代谢组学增强预测模型的外部有效性和性能指标。
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-05 DOI: 10.1093/qjmed/hcag269
Hefziba Lorences Noguera, Esteban Cárdenas-Durán
{"title":"External Validity and Performance Metrics in a Metabolomics-Enhanced Prediction Model for Residual Pulmonary Vascular Obstruction.","authors":"Hefziba Lorences Noguera, Esteban Cárdenas-Durán","doi":"10.1093/qjmed/hcag269","DOIUrl":"https://doi.org/10.1093/qjmed/hcag269","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthy-Adherer Bias May Confound the Association Between PCSK9 Inhibitors and Incident Heart Failure. 健康粘附者偏倚可能混淆PCSK9抑制剂与心力衰竭之间的关系。
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-05 DOI: 10.1093/qjmed/hcag278
Esteban Cardenas-Duran, Hefziba Lorences-Noguera
{"title":"Healthy-Adherer Bias May Confound the Association Between PCSK9 Inhibitors and Incident Heart Failure.","authors":"Esteban Cardenas-Duran, Hefziba Lorences-Noguera","doi":"10.1093/qjmed/hcag278","DOIUrl":"https://doi.org/10.1093/qjmed/hcag278","url":null,"abstract":"","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opportunistic Diagnosis of Osteoporosis through CT Pulmonary Angiography for Suspected Pulmonary Embolism. CT肺血管造影对疑似肺栓塞骨质疏松症的机会性诊断。
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-10-05 DOI: 10.1093/qjmed/hcag267
Ami Schattner, Yair Glick, Valeria Vishnevski, Ina Dubin
{"title":"Opportunistic Diagnosis of Osteoporosis through CT Pulmonary Angiography for Suspected Pulmonary Embolism.","authors":"Ami Schattner, Yair Glick, Valeria Vishnevski, Ina Dubin","doi":"10.1093/qjmed/hcag267","DOIUrl":"https://doi.org/10.1093/qjmed/hcag267","url":null,"abstract":"<p><strong>Background: </strong>CT pulmonary angiography (CTPA) ordered to confirm or exclude pulmonary embolism (PE) often reveals incidental findings. Its yield in the opportunistic detection of osteoporosis, a prevalent, under-diagnosed condition, is less clear.</p><p><strong>Aim: </strong>Evaluate osteoporosis and fragility fractures in CTPAs.</p><p><strong>Design: </strong>Retrospective review of consecutive CTPAs, compared to the initial imaging report and previous diagnosis.</p><p><strong>Methods: </strong>CTPAs review by a consultant radiologist and pertinent clinical data from patients' charts.</p><p><strong>Results: </strong>A total of 517 CTPAs (52.6% women, median 70-years-old) were included. PE was identified in 19%. Varied other significant findings were identified, either acute or incidental. Osteoporosis was more than twice as common as PE, found in 211/517 (41%), but it was previously known in 20/211 (4%) and treated in 8 (1.5%). One quarter of the patients with osteoporosis had fragility fractures in the thoracic vertebrae (53/211, 10% of the entire cohort). The primary radiological report named osteoporosis in only 9/211 (1.5%) and fragility fractures in 3/53 (5.5%).</p><p><strong>Conclusion: </strong>CTPA can be routinely applied to include evaluation of the vertebral column for osteoporosis, a prevalent and notoriously underdiagnosed and undertreated serious condition of older adults.</p>","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Birt-Hogg- Dubé Syndrome Masquerading as Multiple Infected Pulmonary Cysts. 伪装成多重感染肺囊肿的伯特-霍格-杜伯斯综合征。
IF 8.9 4区 医学
QJM: An International Journal of Medicine Pub Date : 2026-09-30 DOI: 10.1093/qjmed/hcag272
Aparna Anil Nair, Aswathy Thazhakottuvalappil, Ameer Kavarathukudy Azeez, Arjun Padmanabhan, Aswathy Girija
{"title":"Birt-Hogg- Dubé Syndrome Masquerading as Multiple Infected Pulmonary Cysts.","authors":"Aparna Anil Nair, Aswathy Thazhakottuvalappil, Ameer Kavarathukudy Azeez, Arjun Padmanabhan, Aswathy Girija","doi":"10.1093/qjmed/hcag272","DOIUrl":"https://doi.org/10.1093/qjmed/hcag272","url":null,"abstract":"<p><p>Birt-Hogg-Dubé syndrome (BHD) is a rare autosomal dominant disorder characterized by pulmonary cysts, fibrofolliculomas, and renal neoplasms. We report a 26-year-old woman who presented with multiple large infected cyst. This case highlights the importance of considering BHD in young patients presenting with cystic lung disease, even in the absence of characteristic cutaneous or renal manifestations.</p>","PeriodicalId":20806,"journal":{"name":"QJM: An International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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