Psychiatria Danubina最新文献

{"title":"IS SOCIAL ANXIETY ALWAYS «SOCIAL»? AN INVESTIGATION OF PERSONALITY COGNITIVE AND AUTISTIC FACTORS.","authors":"Anastasiia Gradskova, Alexey Pavlichenko, Olga Karpenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Social anxiety (SA) disorder is a common psychological condition; however, its boundaries with autism spectrum disorder remain a subject of debate. This study examines the contribution of personality, cognitive, and autistic traits to manifestations of SA in adults. To assess how personality, cognitive, and autistic traits affect SA and to define the impact of autistic features on its development.</p><p><strong>Methods: </strong>The study included 72 adults (42 women, 30 men) over 18, with different levels of SA and autistic traits. Participants completed several questionnaires: Social Anxiety and Social Phobia Questionnaire, HEXACO-60-PI-R60 Personality Questionnaire, Hostility Scale, Cognitive Styles Questionnaire, Autism Spectrum Quotient, Behavior Self-Regulation Style Questionnaire, and an Emotional Intelligence Test.</p><p><strong>Results: </strong>Two groups were studied: (A) high SA with low autistic traits, and (B) high SA with high autistic traits. T-tests and regression analyses were used. No significant differences in overall SA were found between the groups; however, individuals with pronounced autistic traits exhibited greater anxiety in situations requiring initiative and being under observation. Group B demonstrated higher scores on all autism spectrum scales and distinctive personality profiles (low extraversion, high honesty/humility, vigilance, and negativism. Regression analysis revealed distinct predictive factors for SA in the two groups. For Group A this included the following parameters: Liveliness, lower Sociability, decreased Modeling of Conditions, heightened Sentimentality and increased Attention to Detail (89% of the variance in SA scores). For Group B they included low Social Self-Esteem, reduced Flexibility, diminished Reliability, elevated Dependence, and stronger Field Independence (92% of the variance in SA scores).</p><p><strong>Conclusion: </strong>Personality and cognitive predictors of SA differ depending on the presence of autistic traits. The data confirm the necessity of a differentiated diagnostic and therapeutic approach. Future studies should employ longitudinal research designs to investigate causal relationships between variables.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"272-277"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SUICIDALITY IN YOUTH POPULATIONS: DATA FROM A CONSULTATION SETTING.","authors":"Gianmarco Cinesi, Agnese Sciolto, Chiara Miriam Carioti, Francesca Di Maio, Elena Sofia Gaias, Francesca Scopetta, Filippo De Giorgi, Giulia Menculini","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Adolescents and young adults present elevated suicide risk, which remains a major public health concern. This study aims to characterize the clinical and psychosocial features of adolescents and young adults referred for psychiatric consultation after a suicide attempt.</p><p><strong>Subjects and methods: </strong>We conducted a retrospective observational study at the University Hospital of Perugia, Italy, analyzing 72 patients aged 14-35 who received their first psychiatric evaluation during medical hospitalization. Patients were divided into two groups: those referred after a suicide attempt (SA group, n=36) and those referred for other psychiatric concerns (non-SA group, n=36). Data were extracted from structured consultation reports and included sociodemographic, clinical, and psychopathological variables. Bivariate analyses compared the two groups using appropriate statistical tests.</p><p><strong>Results: </strong>Compared to the non-SA group, the SA group had significantly higher rates of unemployment, positive psychiatric family history, previous suicide attempts, insomnia prior to admission, anxiety symptoms with both psychic and somatic features, personality disorders, and mood stabilizer use. SA patients also showed lower cooperativeness during interviews and were more likely to be assessed with suicidal ideation. More than one third of SA patients were assessed as euthymic post-attempt.</p><p><strong>Conclusions: </strong>Key clinical markers of suicide risk in youths may include unemployment, family psychiatric history, insomnia, anxiety with somatic and psychic features, and personality disorders. The clinical profile of suicide attempters suggests a possible contribution of bipolar spectrum diathesis and affective dysregulation. Early, multidimensional risk assessment and integrated intervention strategies in liaison psychiatry are essential to improve detection and prevention of suicidality in youth.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"300-304"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE IMPACT OF CLIMATE CHANGE ON MENTAL HEALTH.","authors":"Magdalena Nowak-Andraka, Wiktor Bednarski, Weronika Siemieniuk, Malgorzata Feret, Krzysztof Krysta","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Climate change is increasingly affecting not only physical health but also mental well-being. Psychological consequences such as eco-anxiety, depression, and post-traumatic stress disorder (PTSD) following climate-related disasters are being reported with growing frequency.</p><p><strong>Subjects and methods: </strong>This study was conducted with mental health professionals who attended the Medforum Psychiatry Congress in 2024. A 22-question, closed-ended questionnaire was used to assess perceptions of the impact of climate change on mental health, the prevalence of eco-anxiety, and workplace preparedness for responding to climate-related disasters.</p><p><strong>Results: </strong>A total of 208 individuals participated in the survey. Of those, 51.9% rated the impact of climate change on mental health as moderate, and 13.9% considered it to be very significant. Although eco-anxiety is increasingly recognized by professionals, most admitted that they rarely encounter patients who report this issue directly.</p><p><strong>Conclusions: </strong>Climate change affects mental health in two ways: directly, through the experience of disasters, and indirectly, by inducing chronic anxiety. Educational initiatives and the implementation of procedures to support mental health during climate-related crises are essential.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"434-437"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NEUROMODULATION IN PSYCHOGERIATRICS: EMERGING EVIDENCE AND FUTURE DIRECTIONS.","authors":"Laurent Elkrief, Giovanni Briganti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Late-life mental illnesses, particularly treatment-resistant late-life depression, present a significant public health challenge due to complex interactions with medical comorbidity, polypharmacy, and neurocognitive disorders. Standard pharmacological treatments are often limited by efficacy and tolerability issues in this population. Neuromodulation has emerged as an essential therapeutic modality, offering targeted treatment that can circumvent systemic side effects. This narrative review provides a critical synthesis of the evidence for established neuromodulation techniques - Electroconvulsive Therapy (ECT), Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct Current Stimulation (tDCS), and Vagus Nerve Stimulation (VNS) - and explores emerging approaches like Transcranial Focused Ultrasound (tFUS) within psychogeriatric populations. The application of these techniques is governed by a trade-off between efficacy, safety, and logistical burden. ECT remains the gold-standard for severe presentations, such as psychosis or catatonia, despite its cognitive risks. rTMS provides a powerful balance of efficacy and tolerability for non-psychotic TRD. tDCS and non-invasive VNS offer excellent safety profiles and potential for home-based administration, expanding access and showing promise for cognitive indications. While the clinical roles of these modalities are clarifying, the path forward requires addressing critical gaps. Future research must prioritize methodologically rigorous, geriatric-specific trials, the development of biomarkers to guide personalized treatment, and an unwavering focus on the ethical complexities of assessing capacity and obtaining informed consent. Integrating these imperatives will enable the field to deliver precise, effective, and patient-centered care for older adults.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"112-119"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RESEARCH ADVANCES IN CLINICAL PSYCHOLOGY OF CHRONIC DISEASES.","authors":"Mariagrazia Di Giuseppe, Chiara Spatola, Emanuele Maria Merlo, Orlando Silvestro, Concetto Mario Giorgianni, Giada Juli, Antonino Catalano, Gabriella Martino","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic diseases represent one of the most pressing global health challenges, with increasing prevalence due to aging populations and lifestyle-related factors. In recent decades, clinical psychology has played a pivotal role in understanding and managing the psychological aspects of chronic illnesses. This paper aims to synthesize current research on the bidirectional relationship between psychological factors and chronic disease progression, emphasizing recent advances in theoretical models, empirical findings, and clinical interventions. Defensive functioning, alexithymia, and psychological flexibility emerge as crucial dimensions. A greater use of mature defense mechanisms appears to be linked to better psychosomatic well-being, while reliance on immature defenses is associated with increased anxiety-depressive symptoms and a more negative perception of health. Similarly, higher levels of alexithymia are connected to greater psychological distress and reduced interoceptive awareness. In contrast, psychological flexibility shows a protective role, promoting better mental health and adaptive functioning. These findings highlight the need to deepen our understanding of the psychological underpinnings of chronic illness, especially through approaches that account for individual differences in emotional regulation and coping. While existing research has offered promising directions, the field would benefit from longitudinal studies and the systematic inclusion of psychological variables in chronic care pathways. Integrating such perspectives may support more comprehensive and person-centered interventions, improving both clinical outcomes and patients' subjective experiences.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"56-62"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHALLENGES IN IMPLEMENTING A 1 HOUR WEEKLY WALK ACTIVITY AND ASSESSING SELF-ESTEEM WITHIN RESIDENTIAL PSYCHIATRIC CARE.","authors":"Madeleine Bennert, Alexandra Putineanu, Damien De Cnuydt, Agathe Coquelet, Lopez René Llano, Juan Martin Tecco","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Patients with psychotic disorders often have low levels of physical activity, and there's limited data on implementing exercise programs and systematically evaluating physical health among inpatients. This study, conducted in a closed psychosis unit, aimed to explore the feasibility of a 1-hour weekly walk activity, alongside assessing self-esteem.</p><p><strong>Subjects and methods: </strong>From February 7 to July 11, 2025, patients at the Gaudi unit in Mons, Belgium, specializing in psychotic disorder care, were offered participation in a weekly supervised walk. Out of 64 evaluated inpatients, eligible individuals could choose between a 3 km or 5 km circuit. The study also planned to assess self-esteem using the Rosenberg Self-Esteem Scale (RSES) and to conduct qualitative analysis upon admission.</p><p><strong>Results: </strong>Over 24 weeks, the average walk participation rate was 59.86% (255 out of 426 possible participations). Most preferred the 3 km circuit (75.69%), while fewer chose the 5 km (14.9%) or the 8 km combination (9.41%). However, comprehensive assessments (RSES, qualitative evaluation) were only offered to 12 of the 64 patients. Only 6 completed the qualitative evaluation, and 10 completed the RSES. This low assessment completion rate suggests the evaluations might be too challenging for this population.</p><p><strong>Conclusion: </strong>Implementing a weekly walk activity in a closed psychosis unit is feasible. Nevertheless, integrating a study protocol for comprehensive physical and psychological assessments proved challenging. Future projects would require adapting assessment methods to be more realistic for this setting.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"398-402"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RELATION BETWEEN CLINICAL AND SOCIAL CHARACTERISTICS OF PATIENTS HOSPITALIZED FOR A DEPRESSIVE EPISODE AND SELF-EFFICACY: A STUDY USING A NEW RESEARCH DOMAIN CRITERIA (RDOCS) INSPIRED EVALUATION BATTERY.","authors":"Avigaelle Amory, Simon Van Haverbeke, Philippe de Timary, Geraldine Petit","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Depression is a common disabling disease. Self-efficacy has been identified as a key factor in the prognosis of depression, as it influences how affected individuals cope and manage depressive symptoms.</p><p><strong>Subjects and methods: </strong>This study aims to gain a deeper understanding of the factors that contribute to the development of personal self-efficacy by using a framework inspired by the Research Domain Criteria (RDoC). A total of 41 adult inpatients meeting DSM-5 criteria for major depressive disorder were assessed on a comprehensive battery of measures spanning emotional, cognitive, and social domains.</p><p><strong>Results: </strong>Multiple linear regression analyses revealed that trait emotional intelligence and particularly its well-being and self-control subscales, was the most robust predictor of self-efficacy. Satisfaction with social support emerged as a secondary contributor.</p><p><strong>Conclusions: </strong>These findings underscore the importance of targeting emotional intelligence and social support in therapeutic interventions for depression, suggesting that fostering adaptive emotion regulation and enhancing perceived support may bolster patients' confidence in their ability to manage depressive challenges.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"267-271"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE IMPACT OF SEX HORMONE LEVELS ON COGNITIVE FUNCTIONING IN WOMEN WITH SCHIZOPHRENIA - SCOPING REVIEW.","authors":"Krzysztof Krysta, Beata Tredzbor, Ewa Martyniak, Agnieszka Kozmin-Burzynska, Katarzyna Piekarska-Bugiel, Roman Wojnar, Rafal Bies, Marek Krzystanek","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Cognitive impairment is a core and disabling feature of schizophrenia, with a profound impact on functional outcomes. Female patients often demonstrate better cognitive profiles than males, suggesting a potential modulatory role of sex hormones. Estrogens, particularly estradiol, have been hypothesized to exert neuroprotective effects via modulation of neurotrophic, neurotransmitter, and inflammatory pathways. However, evidence regarding the relationship between sex hormone levels and cognition in schizophrenia remains scattered and inconclusive.</p><p><strong>Methods: </strong>This scoping review synthesized evidence from clinical and preclinical studies examining the association between endogenous estrogen levels or estrogen-based treatments and cognitive functioning in women with schizophrenia. We included peer-reviewed literature addressing hormonal fluctuations across the menstrual cycle, menopause, and in response to antipsychotic treatment, with specific focus on estradiol and selective estrogen receptor modulators.</p><p><strong>Results: </strong>Findings suggest that low estrogen levels may be linked to more severe negative symptoms and poorer cognitive performance in female patients. Studies investigating menstrual cycle phases report mixed results, while evidence from animal models indicates potential cognitive benefits of estrogenic compounds. Raloxifene has shown promise in mitigating cognitive deficits when administered during sensitive developmental periods. However, large-scale hormonal interventions in postmenopausal women have produced inconsistent results, likely due to differences in timing, dosage, and individual neurobiological context.</p><p><strong>Conclusions: </strong>Sex hormone levels, especially estradiol, appear to influence cognitive outcomes in women with schizophrenia, though findings are heterogeneous. Future research should address methodological inconsistencies and explore phase-specific, personalized hormonal strategies. A deeper understanding of hormonal-cognitive interactions may inform more effective, sex-sensitive treatment approaches in schizophrenia.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"154-159"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COERCIVE PSYCHIATRIC TREATMENT: UNRAVELING SOCIODEMOGRAPHIC PATTERNS AND THE POLYPHARMACY CHALLENGE.","authors":"Karina Cernika, Jelena Vrublevska","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This study aims to analyse certain populations' sociodemographic factors and to investigate the use of polypharmacy for inpatients assigned to involuntary treatment at the National Center of Mental Health, Riga, Latvia.</p><p><strong>Methods: </strong>A retrospective review of clinical data was undertaken in adult inpatients assigned to involuntary psychiatric treatment in the period from December 17th, 2024, till February 4th, 2025. The data about the participants' sociodemographic factors, hospitalisation duration, diagnosis, and treatment strategies were obtained from the hospital's databases. Only data from a fixed 30-day window at the time of analysis were considered, irrespective of hospitalization duration, to ensure consistency and avoid bias from ongoing treatment modifications. The Antipsychotic Total Daily Dose Calculator was used to assess polypharmacy load by estimating the BNF (British National Formulary) coefficient relative to the recommended maximum daily dose. All data were collected in MS Excel and analysed using IBM SPSS 29.0.1.0.</p><p><strong>Results: </strong>The study included 88 inpatients with compulsory medical measures. Results showed a mean age of the participants equal to 41.49±2.41 years, males' dominance making 86.36% (n=76) of the study group, and schizophrenia (F20, ICD-10) noted as the most dominant diagnostic category. Polypharmacy with more than one antipsychotic medication was observed in 89.77% (n=79) of the inpatients. The most common treatment combination was an antipsychotic with a mood stabilizer, prescribed to 44.32% (n=39) of participants. Treatment was primarily guided by antipsychotics, with haloperidol emerging as the most commonly used drug, representing 72.72% (n=64) of the cases, and mood stabilizers received by 57.95% (n=51) of the inpatients. The analysis revealed that 34.09% (n=30) of participants had a BNF coefficient within the recommended maximum daily dose, while the majority, or 65.9% (n=58), exceeded the recommended threshold.</p><p><strong>Conclusions: </strong>This study contributes to existing knowledge of currently available data about polypharmacy in psychiatric practice and certain population groups undergoing involuntary hospitalisation. The results about treatment patterns may support the optimization of treatment practices and warrant closer attention to safety, side effect profiles, and possible long-term outcomes when polypharmacy is used.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"362-367"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE DEATH OF VICTIMS AS A RESULT OF SCHIZOPHRENIA OR OTHER SERIOUS MENTAL ILLNESS; WHAT HAVE WE LEARNT OVER THE YEARS?","authors":"Mark Agius, Michaela Agius, Anton Grech","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>From time to time, tragic cases occur when patients with serious Mental illness commit homicide. We describe two cases which are in the public domain.These cases are not isolated incidents but part of a broader, systemic failure to provide sustained, assertive, and well-resourced community-based mental health care. It is crucial that the techniques of Assertive Outreach we have discussed are not only adopted in principle but also fully integrated into everyday practice, backed by proper funding, staff training, and institutional support. Without this commitment, we risk continuing the tragic cycle of preventable deaths, where both patients with severe mental illness and innocent bystanders pay the price for gaps in the system. By applying assertive outreach models effectively, we have the opportunity to change the trajectory of care, ensuring that vulnerable individuals receive the intensive, proactive support they need to remain stable, safe, and ultimately, to prevent such tragedies from happening again.</p>","PeriodicalId":20760,"journal":{"name":"Psychiatria Danubina","volume":"37 Suppl 1","pages":"446-449"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}