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Regarding "Stress management and In Vitro Fertilization (IVF): A pilot randomized controlled trial". 关于“压力管理和体外受精:一项试点随机对照试验”。
Psychiatrike = Psychiatriki Pub Date : 2022-04-27 DOI: 10.22365/jpsych.2022.076
S. Komiya, M. Banno, Yuki Itagaki
{"title":"Regarding \"Stress management and In Vitro Fertilization (IVF): A pilot randomized controlled trial\".","authors":"S. Komiya, M. Banno, Yuki Itagaki","doi":"10.22365/jpsych.2022.076","DOIUrl":"https://doi.org/10.22365/jpsych.2022.076","url":null,"abstract":"Koumparou et al.1 recently published a randomized controlled trial (RCT) on the effectiveness of psychological interventions (stress management training, SMT) for women planning in vitro fertilization (IVF). They concluded that while the effect of SMT was limited in terms of IVF outcome, it resulted in a significant reduction of stress levels in infertile patients. Since most women undergoing infertility treatment are exposed to high psychological stress,2 this study may be of great value in demonstrating the need for proactive SMT to maintain infertile women's mental health and motivation to continue treatment. However, we are concerned that the reliability of this RCT has been compromised in several ways. First, the registration of the RCT was not clearly stated. According to The CONsolidated Standards of Reporting Trials (CONSORT) 2010 guidelines, a prospective registration of the RCT is required, which prevents unnecessary concerns about the bias of results selection.3,4 Second, the lack of specific figures on the background of the participants in the case and control groups risks distorting the RCT results. The article states that there was no significant difference between the two groups. However, since aging and prolonged infertility treatment increase the psychological burden on infertile patients,5 detailed background information is necessary to interpret the results of an RCT accurately. Selection bias could not be determined, which weakened the validity of this RCT. Furthermore, the absence of any mention of case dropout makes the conclusions of this RCT uncertain; a discussion of cases demonstrating difficulty in completing an 8-week psychological program would clarify whether temporary SMT would show efficacy for patients. Finally, it is essential to note that the details of IVF have not been clarified. Since the timing of the SMT and IVF-ET cycles or details of the IVF-ET protocol were not shown, this RCT could not be used as a reference for IVF facilities to actually operate SMT. There is no doubt that psychological interventions are necessary for infertile patients exposed to high psychological stress, but this RCT has many details that have not been clarified, and the conclusions are attenuated. As details become clearer, this RCT will provide a foundation for the active use of SMT in infertility treatment settings.","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84530916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive changes in health locus of control attributions after behavioral analysis in patients with panic disorder and/or agoraphobia. 惊恐障碍和/或广场恐怖症患者行为分析后健康控制源归因的认知变化
Psychiatrike = Psychiatriki Pub Date : 2022-04-27 DOI: 10.22365/jpsych.2022.075
Y. Kasvikis, T. Mitsopoulou, E. Alexiou
{"title":"Cognitive changes in health locus of control attributions after behavioral analysis in patients with panic disorder and/or agoraphobia.","authors":"Y. Kasvikis, T. Mitsopoulou, E. Alexiou","doi":"10.22365/jpsych.2022.075","DOIUrl":"https://doi.org/10.22365/jpsych.2022.075","url":null,"abstract":"Patients with Panic Disorder and / or Agoraphobia (PD +/- Ag) attribute their mental health more to external factors and less to internal, while after behavior treatment (BT) their external attributions decrease and internal attributions increase. We examined whether these cognitive changes observed at the end of BT, begin earlier. Forty patients with PD +/- Ag were assessed on the Multidimensional Health Locus of Control Scale, before and after the diagnostic and psychoeducational sessions that precede the clinical implementation of BT. Decreased health attributions to significant others (t = 4.22, p < 0.01), and an increase trend to self (t = -0.78, p = 0.43) were observed, which are compatible with the active role patients need to adopt in the clinical application of BT.","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85045878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modern bioethical issues: Euthanasia, physician assisted suicide and abortion. Comparative study of attitudes between physicians and law professionals. 现代生物伦理问题:安乐死,医生协助自杀和堕胎。医师与法律专业人员态度的比较研究。
Psychiatrike = Psychiatriki Pub Date : 2022-03-28 Epub Date: 2021-11-26 DOI: 10.22365/jpsych.2021.043
Nafsika Malikentzou, Athanasios Douzenis, Fotios Chatzinikolaou, Panagiota Bali, Ioannis Michopoulos
{"title":"Modern bioethical issues: Euthanasia, physician assisted suicide and abortion. Comparative study of attitudes between physicians and law professionals.","authors":"Nafsika Malikentzou,&nbsp;Athanasios Douzenis,&nbsp;Fotios Chatzinikolaou,&nbsp;Panagiota Bali,&nbsp;Ioannis Michopoulos","doi":"10.22365/jpsych.2021.043","DOIUrl":"https://doi.org/10.22365/jpsych.2021.043","url":null,"abstract":"<p><p>We aimed to examine and compare the attitudes of physicians and law professionals on modern bioethical issues. Euthanasia, physician assisted suicide and abortion were selected for this study, as they underline the conflict between human life as a fundamental value, and the individual's right to self-determination. The demand of euthanasia and physician assisted suicide services reflects each person's right to decide on the way their life will end, while the legalization of abortion determines the individual's right to self-determination. These are complex issues with moral, religious and social implications, and as such tend to divide public opinion. In order to investigate their attitudes, physicians of all specialties, as well as law professionals from all over Greece, were invited to participate in the study. In total, 220 professionals responded to the call and participated in the survey. The professionals involved showed fairly high rates of agreement in all the issues studied, but a significant difference in results was found when the occupation of participants was set as a criterion, with physicians being more negative to euthanasia, physician assisted suicide and abortion than lawyers. Religiousness, age and male sex were negatively correlated with \"positive\" attitudes towards euthanasia, physician assisted suicide and abortion. Moreover, participants' attitudes towards euthanasia and physician assisted suicide were found to predict their attitudes towards abortion, indicating a single ideological direction of agreement or disagreement, accordingly. Individuals' attitudes and opinions are complicated issues, not easy to be categorized. However, it is of scientific interest to shape a legislative framework that is close to the social consensus, ideological evolution and moral needs. This study tried to pave the way for a modern approach to the issues of euthanasia, physician assisted suicide and abortion.</p>","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39802149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The effects of parental divorce on children. 父母离婚对孩子的影响。
Psychiatrike = Psychiatriki Pub Date : 2022-03-28 Epub Date: 2021-11-26 DOI: 10.22365/jpsych.2021.040
Hüseyin Çaksen
{"title":"The effects of parental divorce on children.","authors":"Hüseyin Çaksen","doi":"10.22365/jpsych.2021.040","DOIUrl":"https://doi.org/10.22365/jpsych.2021.040","url":null,"abstract":"<p><p>Family is very important for development of children. Divorce is a life event with a high level of stress for the entire family. Children are dependent on parents and disadvantaged during divorce because it is out of their control.1 Herein, we present our observations about children whose parents separated or divorced to increase the awareness of physicians about the negative effects of divorce. Individuals affected by parental divorce have a higher risk of developing a variety of mental health conditions including emotional and behavioral disorders, poor school performance, depression, anxiety, suicidal ideation, suicide attempt, distress, smoking and substance abuse.2,3 Externalizing problems in girls precede and predict later parental divorce. Post-divorce problems in children vary by raters, and may depend on the time lapse since divorce.4 Lansford et al 5 noted that early parental divorce/separation is more negatively related to trajectories of internalizing and externalizing problems than is later divorce/separation, whereas later divorce/separation is more negatively related to grades. In another study, divorce in parents was significantly associated with higher alcohol use disorder, higher cigarette dependence and higher water pipe dependence in adolescents.6 In the study of Tullius et al 7 the levels of both internalizing and externalizing problems were significantly higher in the period after parental divorce, but not in the period before divorce, with a persistent and increasing effect over the follow-up periods compared to adolescents not experiencing divorce. Zeratsion et al 8 reported that parental divorce in late adolescence does not lead to mental health problems, as has been shown before, while such problems may prevail among young adolescents. This does not mean that parental divorce creates less problems in late adolescence than before but these youths might have developed adjustment abilities against health effects as divorce have turned to be more common. In our clinical practice, we have also observed various emotional, behavioral, psychosomatic, and conversion disorders in children, particularly in preadolescents and adolescents, before and/or after a separation or divorce of parents. Children often lack information and skills to overcome the challenges that the divorce carries. Conflicting relationships between parents make up the biggest obstacle that makes it difficult for a child to successfully deal with changes in the family. Even though parents deal with heavy feelings, it is desirable to put them the child and his interests in the first place. In order to stabilize the family system, 2 to 4 years are usually needed.1 Physicians can assist families by providing support and advice, and advocating for children within systems that serve separating families. Physicians can provide information so that individuals who work with such children recognize, and are sensitive to, their individual needs, and provide support","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39801699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Substance use during the COVID-19 pandemic: What is really happening? COVID-19大流行期间的物质使用:到底发生了什么?
Psychiatrike = Psychiatriki Pub Date : 2022-02-21 DOI: 10.22365/jpsych.2022.072
E. Mellos, T. Paparrigopoulos
{"title":"Substance use during the COVID-19 pandemic: What is really happening?","authors":"E. Mellos, T. Paparrigopoulos","doi":"10.22365/jpsych.2022.072","DOIUrl":"https://doi.org/10.22365/jpsych.2022.072","url":null,"abstract":"The COVID-19 pandemic is associated with increased levels of anxiety, fear, sadness, difficulty adjusting, symptoms of post-traumatic stress disorder and suicidality, both in the general population and specific subgroups. The presence of this type of psychopathology increases the risk of involvement with or worsens the use of addictive substances and alcohol as a maladaptive coping strategy.1 According to these data, people with substance use disorders are a population at high risk for COVID-19 infection and serious illness. Α large controlled retrospective case study in the US found that people with substance use disorders are significantly more vulnerable to COVID-19 and its complications (primarily those with opioid use disorder OR = 10.21 and with tobacco use disorder OR = 8.25), and that the course and outcome of the disease (hospitalization, death) was worse than in non-dependent individuals. The main culprits are increased physical co-morbidity (frequent respiratory and cardiovascular problems), poor health and living conditions, marginalization and difficulties in accessing health services. 2,3 Ιnternational epidemiological data during the first months of the pandemic regarding the use of addictive substances do not lead to safe conclusions. A cross-sectional online epidemiological study conducted on a sample of 36,538 adults from 21 European countries between April and July 2020 found an overall decrease in alcohol use, which was mainly attributed to the reduction of heavy episodic consumption, while at the same time an increase in alcohol consumption among people with severe alcohol use was recorded. Τhe use of cannabis and nicotine showed increasing trends, as well as the use of cocaine, but to a lesser extent, while the use of MDMA (ecstasy) showed a decrease.4 In a review of 45 cross-sectional studies conducted between December 2019 and November 2020, alcohol use was on the rise overall, despite geographical variations, as was the use of other addictive substances, cannabis in particular.5 It should be noted that those who increased alcohol use during quarantine were those exhibiting higher levels of negative emotionality mechanisms.6 In Greece, an online cross-sectional survey in April 2020 in the general population during the first lockdown showed a reduction in alcohol use (43.7% of alcohol users reduced or quit), a reduction in cannabis (67.3% quit), while 33.3% increased nicotine use. These changes were attributed to the limitation of alcohol availability, social distancing, changes in daily routine and income reduction.7,8 Also, wastewater samples from Athens, analyzed by the Laboratory of Analytical Chemistry of EKPA, showed a significant increase in the use of cocaine (67%), amphetamine (350%) and methamphetamine (37%), and a decrease in the use of MDMA (- 38%) during the first lockdown, compared to the corresponding period of the previous year.9 Analysis of wastewater samples from other European cities \"suggest that levels o","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81190565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Exhaustion and burnout in the healthcare system in Greece: A cross-sectional study among internists during the COVID-19 lockdown. 希腊医疗保健系统的疲劳和倦怠:COVID-19封锁期间内科医生的横断面研究。
Psychiatrike = Psychiatriki Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.067
E. Karlafti, Emmanouil S. Benioudakis, E. Barouxi, G. Kaiafa, T. Didangelos, K. Fountoulakis, S. Pagoni, C. Savopoulos
{"title":"Exhaustion and burnout in the healthcare system in Greece: A cross-sectional study among internists during the COVID-19 lockdown.","authors":"E. Karlafti, Emmanouil S. Benioudakis, E. Barouxi, G. Kaiafa, T. Didangelos, K. Fountoulakis, S. Pagoni, C. Savopoulos","doi":"10.22365/jpsych.2022.067","DOIUrl":"https://doi.org/10.22365/jpsych.2022.067","url":null,"abstract":"The COVID-19 pandemic has rapidly changed everyday life around the world. The situation created by the COVID-19 pandemic has been shown to be associated with severe mental health problems in frontline medical and nursing staff. The aim of this study was to investigate exhaustion, disengagement, secondary traumatic stress, compassion satisfaction, burnout, as well as depression, anxiety and stress among internists in Greece, during the second lockdown period. Internists were approached through the Internal Medicine Society of Greece and a total of 117 participated in the study (response rate: 15.3%). The participants responded through a Google form on the Depression, Anxiety and Stress Scale - 21, the Oldenburg Burnout Inventory (OLBI) and the Professional Quality of Life Scale version 5 (ProQOL-5). Exhaustion was found in the majority of the participants (88%), 65.8% met the criteria for at least moderate levels of compassion satisfaction and 71.8% presented moderate levels of burnout. Furthermore, about half of the participants met the criteria for moderate to extremely severe levels of depression, anxiety and stress. Finally, regression analyses showed that depression was associated with both the OLBI and ProQOL-5 scales. The majority of the internists, during the lockdown period in Greece, were evaluated as \"exhausted\", with high rates of negative psychological symptoms. The present study, despite the limitations, highlights the impact of the COVID-19 pandemic on internists, which triggered a shift in attention onto the treatment, and especially the prevention, of stressful situations for health professionals.","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74124299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Association of cognitive function of non-demented elderly primary care attendees with physical, mental, and sociodemographic factors. 非痴呆老年初级保健参与者的认知功能与身体、精神和社会人口因素的关联。
Psychiatrike = Psychiatriki Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.069
Aglaia Roganaki, T. Vorvolakos, Elpida Sokou, G. Tripsianis, Theodoros Konstadinidis, M. Samakouri
{"title":"Association of cognitive function of non-demented elderly primary care attendees with physical, mental, and sociodemographic factors.","authors":"Aglaia Roganaki, T. Vorvolakos, Elpida Sokou, G. Tripsianis, Theodoros Konstadinidis, M. Samakouri","doi":"10.22365/jpsych.2022.069","DOIUrl":"https://doi.org/10.22365/jpsych.2022.069","url":null,"abstract":"Preservation of a population's cognitive functions is a matter of increased concern for all healthcare systems. The detection of factors that are associated with cognitive functions is a matter of increased interest to both the treatment of vulnerable individuals and the implementation of strategies to delay age-related cognitive decline. This study aimed to highlight sociodemographic, physical, and mental health factors associated with the cognitive function in non-demented elderly primary health care attendees. The sample consisted of 362 primary health care attendees aged 60 years or above. A questionnaire regarding sociodemographic and physical health history, along with a battery of psychometric instruments consisting of the Test Your Memory (TYM) test, Geriatric Depression Scale-Short Form (GDS-15), Short Anxiety Screening Test (SAST), and World Health Organization-Five Well-Being Index (WHO-5), were given to all participants.Participants who scored below 39/40 in the TYM, which is the cut-off point for dementia screening in the version of the test we used, were excluded from further assessment. For the rest of the participants, 267 in total, their TYM scores were significantly and negatively correlated with age and SAST scores. Participants with lung and vascular health history problems scored lower in the TYM, as did those with poor education, who lived alone, and who lived in Alexandroupolis. Finally, healthy participants scored higher than individuals with at least one medical condition. Linear multiple regression analysis revealed a model (adjusted R2 = 25.80, F = 10.11, p < 0.001) with three factors (age (beta = -0.32), lung problems (beta = -0.23), and vascular factors (beta = -0.20) that could significantly predict 25.80% of the variance in TYM scores. Preservation of physical health, especially lung and vascular health, along with anxiety alleviation help to counterbalance the negative effect of aging on cognitive function in non-demented elderly primary care attendees.","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84394495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of a hybrid arts-based Cognitive Behavioral Therapy intervention for patients with non-malignant chronic pain. 基于艺术的混合认知行为疗法对非恶性慢性疼痛患者的干预效果。
Psychiatrike = Psychiatriki Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.064
Asimina Kalmanti, C. Batistaki, C. Christodoulou, Georgia Gerolouka-Kostopanagiotou, A. Douzenis, I. Michopoulos
{"title":"Effectiveness of a hybrid arts-based Cognitive Behavioral Therapy intervention for patients with non-malignant chronic pain.","authors":"Asimina Kalmanti, C. Batistaki, C. Christodoulou, Georgia Gerolouka-Kostopanagiotou, A. Douzenis, I. Michopoulos","doi":"10.22365/jpsych.2022.064","DOIUrl":"https://doi.org/10.22365/jpsych.2022.064","url":null,"abstract":"Chronic Pain (CP) is defined as pain that persists or recurs for more than 3 to 6 months and may be conceived as a health condition in its own right. CP is a frequent condition, affecting an estimated 20% of people worldwide and requires special treatment and care. CP can contribute to depression, anxiety, sleep disturbances, poor quality of life and increased health care costs. Psychosocial approaches based on a cognitive conceptualization of pain can provide a solid foundation for research and clinical work. The development of a 10 week-session group treatment was based on key principles from the literature on Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) and Creative Arts Therapy, integrated with advances in research on CP management framework. The aim of this study is to evaluate a CBT-CP arts-based group intervention for patients with non-malignant CP addressing the biopsychosocial factors that influence pain perception. A total of 100 University Pain Management Unit outpatients participated, 50 in the intervention group and 50 in the control group (treatment as usual). In analyses of the pretest-posttest research design intervention including all participants, treatment gains were observed in almost all domains examined: severity of pain measured by the Brief Pain Inventory, conceptualization of mental pain measured by the Orbach and Mikulincer Mental Pain Scale, tolerance for psychological pain measured by the Tolerance for Mental Pain Scale, anxiety and depression levels measured by the Hospital Anxiety and Depression Scale, and quality of life measured by the WHO Quality of Life-BREF Questionnaire. The participants' mean age was 52.3 years and most were female (84%). Findings suggest that postprogram, there was significant reduction in pain intensity (p<0.001), depressive symptoms (p<0.001), confusion about pain (p=0.037), and improvement of emotional distress tolerance (p=0.012) and global health-related quality of life (p<0.001) in the intervention group. Beneficial effects can be expected from the implementation of an integrated CP intervention (including: creative and CBT techniques) reappraising some of the coping responses defined as adaptive within current psychosocial non-malignant CP regimens.","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90653573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychopharmacology of patients with multiple sclerosis in Greece during the period 2017-2019. 2017-2019年希腊多发性硬化患者的精神药理学研究
Psychiatrike = Psychiatriki Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.057
C. Bakirtzis, M. Karakasi, M. Boziki, T. Moysiadis, Dimitra Tsakona, B. Fyntanidou, G. Papazisis, E. Thireos, N. Grigoriadis
{"title":"Psychopharmacology of patients with multiple sclerosis in Greece during the period 2017-2019.","authors":"C. Bakirtzis, M. Karakasi, M. Boziki, T. Moysiadis, Dimitra Tsakona, B. Fyntanidou, G. Papazisis, E. Thireos, N. Grigoriadis","doi":"10.22365/jpsych.2022.057","DOIUrl":"https://doi.org/10.22365/jpsych.2022.057","url":null,"abstract":"Multiple Sclerosis (MS) is highly comorbid with mental disorders in any disease stage, while psychiatric manifestations may precede the onset of neurological symptoms as well as diagnosis. Neuropsychiatric comorbidities are associated with an elevated risk of MS disability progression, and therefore, people with multiple sclerosis (PwMS) with psychiatric comorbidities often experience a significantly lower functional status, perform worse in objective neuropsychological assessment, are less likely to adhere to pharmacological treatment, and exhibit higher levels of disruption of their supportive social environment as compared with \"non-psychiatric\" PwMS. The present study aims to estimate the nationwide use of psychopharmacological agents by PwMS in Greece. Prescription records of the nationwide digital prescription database were analyzed, in order to identify PwMS that have received prescriptions of an antipsychotic, an antidepressant, an anxiolytic or a psychostimulant during a 2-year study period. Pseudo-anonymized prescription records of PwMS (n=21218) were extracted from the Greek nationwide prescription database, dating from June 2017 to May 2019. According to this national level study, psychopharmacological agents are frequently prescribed in PwMS. Antidepressants were prescribed in 36.1% of the study sample, followed by anxiolytics (16.23%), psychostimulants (4.97%) and antipsychotics (3.76%). The proportion of patients under treatment with these agents was increasing with age. Selective serotonin reuptake inhibitors, second generation antipsychotics and benzodiazepines were the most often prescribed agents in each drug category and especially in younger age groups, possibly indicating a better efficacy/side-effect equilibrium, while modafinil was the only psychostimulant prescribed aiming to ameliorate levels of fatigue. A pharmacological preference for antidepressants and psychostimulants was observed in the 40-60 age group (p = 0.02), while antipsychotics and anxiolytics were more frequently prescribed in the >60 age group (p<0.001). Serotonin-norepinephrine reuptake inhibitors were mostly prescribed within the 40-60 age-group. Benzodiazepines were less favored among the >60 age-group. This study highlights the increased prevalence of mental disorders in this patient group. Adequate treatment and monitoring of psychiatric symptomatology, may improve long-term outcomes of the disease, however caution is needed regarding potential drug interactions and side effects.","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79384594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Obsessive-compulsive symptoms in pregnancy: Their relationship with obsessive beliefs and obsessive-compulsive personality traits. 怀孕期间的强迫症状:与强迫信念和强迫人格特征的关系。
Psychiatrike = Psychiatriki Pub Date : 2022-02-01 DOI: 10.22365/jpsych.2022.071
Ekaterini Vasileiou, Panagiota Fexi, A. Spyropoulou, I. Mourikis, Theodoros Chalimourdas, I. Zervas
{"title":"Obsessive-compulsive symptoms in pregnancy: Their relationship with obsessive beliefs and obsessive-compulsive personality traits.","authors":"Ekaterini Vasileiou, Panagiota Fexi, A. Spyropoulou, I. Mourikis, Theodoros Chalimourdas, I. Zervas","doi":"10.22365/jpsych.2022.071","DOIUrl":"https://doi.org/10.22365/jpsych.2022.071","url":null,"abstract":"Literature findings are limited and inconsistent on the relationship between obsessive beliefs and obsessive-compulsive symptoms (OCS) and to our knowledge no data are available in pregnant population. Additionally, an interesting field that has not been adequately studied is the relationship between obsessive-compulsive personality traits and OCS while there are no corresponding studies in perinatal period. The aims of the study were to examine the relationship between OCS presented in pregnancy and obsessive beliefs considered to underlie them as well as their association with obsessive-compulsive personality traits. 30 pregnant women with OCS, regardless of their underlying diagnosis, were recruited from a University Psychiatric Hospital and privately. They completed the Mini International Neuropsychiatric Interview (MINI), the Yale-Brown Obsessive- Compulsive Scale (Y-BOCS), the Dysfunctional Beliefs Questionnaire-44 (OBQ-44), the Leyton Trait Scale and the Hospital Anxiety and Depression Scale (HADS). The main symptoms were aggression (73.3%), contamination (53.3%) obsessions and cleansing/washing (50%), checking (43.3%) compulsions. Pregnant women with obsessive-compulsive personality traits displayed symmetry/exactness obsessions (p=0.020) and cleansing/washing (p=0.011) compulsions as predominant types of OCS and greater severity of compulsions (p=0.049). The results of the logistic regression model suggest that obsessive beliefs of importance/control of thoughts and of responsibility/threat estimation predicted OCS while the belief of perfectionism/certainty did not predict any dimension of OCS. It is noteworthy that most observed relationships between obsessive beliefs and OCS remained even after controlling for variables of anxiety and depression, suggesting that obsessive beliefs have a specific relationship with OCS which is independent of other forms of psychopathology. Depressive symptoms comorbidity increased OCS severity, while in comorbidity with anxiety symptoms no difference in severity of OCS was found. Further research is needed to test our findings in larger and more diverse samples.","PeriodicalId":20741,"journal":{"name":"Psychiatrike = Psychiatriki","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90973411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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