Jurnal Ilmu Kedokteran (Journal of Medical Science)最新文献

Comparations Of Glycated Albumin Among Type 2 Diabetes Mellitus Patient With Normoalbuminuria, Microalbuminuria And Macroalbuminuria 2型糖尿病正常白蛋白尿、微量白蛋白尿和大量白蛋白尿患者糖化白蛋白的比较

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.53-58

Raja Iqbal Mulya Harahap, N. Tristina, Ruri Rizki Anriani

{"title":"Comparations Of Glycated Albumin Among Type 2 Diabetes Mellitus Patient With Normoalbuminuria, Microalbuminuria And Macroalbuminuria","authors":"Raja Iqbal Mulya Harahap, N. Tristina, Ruri Rizki Anriani","doi":"10.26891/jik.v17i1.2023.53-58","DOIUrl":"https://doi.org/10.26891/jik.v17i1.2023.53-58","url":null,"abstract":"Diabetic nephropathy is the most often complication of diabetes mellitus (DM). Complications of diabetic nephropathy can occur through several pathways, one of which is the formation of Advanced Glycation End Products (AGEs) through the formation of Glycated Albumin (GA). Glycated albumin (GA) is a medium-term glycemic control (2-3 weeks), shorter duration than HbA1c (2-3 months). The aim of this study was to compare the levels of GA in T2DM patients with normoalbuminuria, microalbuminuria, and macroalbuminuria. This is a cross-sectional study with subjects were 105 outpatients who had been diagnosed with T2DM by clinicians at Hasan Sadikin Hospital’s Endocrinology Clinic. We examined urinary albumin per Creatinine (u-ACR) and blood GA Increased GA level was found in 75.24% subjects. Kruskal Wallis test in GA serum levels of patients with T2DM normoalbuminuria group, microalbuminuria and macroalbuminuria revealed statistically significant (p <0.001), with median and range of GA in normoalbuminuria 15,9% (12,1-21,89)%; microalbuminuria 20,9% (12,9-47,2)%; dan macroalbuminuria 23,1% (13,6-46,1)%. Statistical analysis showed that the GA serum level was significantly different between T2DM patients with normoalbuminuria and macroalbuminuria, but not between those with microalbuminuria and macroalbuminuria (p=0.001 and p=0.137, respectively). The result showed that the extensive kidney damage at the subject, the higher result of Glycated Albumin level in serum.","PeriodicalId":207188,"journal":{"name":"Jurnal Ilmu Kedokteran (Journal of Medical Science)","volume":"470 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124387765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efek Inhibitor Proteasom Terhadap Gambaran Histopatologi Jantung pada Tikus yang diinduksi Aterosklerosis 蛋白酶抑制剂对诱导动脉粥样硬化的老鼠心脏直肠炎症状的影响

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.66-70

Ilhami Romus, Ismawati Ismawati, Indah Putri Arwandi

引用次数: 0

Pengaruh Monosodium Glutamat Terhadap Fertilitas Pria 谷氨酸二钠对男性受精的影响

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.17-23

Ika Inda Bani, Z. Zulkarnain, G. Gholib

引用次数: 0

Faktor - faktor yang mempengaruhi kunjungan ibu balita ke Posyandu Desa Melayu Besar Kabupaten Rokan Hilir

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.24-31

Y. Yusdiana, Armoni Suci Dewi, Fathiya Azka Putri, Ria Permata Sari

{"title":"Faktor - faktor yang mempengaruhi kunjungan ibu balita ke Posyandu Desa Melayu Besar Kabupaten Rokan Hilir","authors":"Y. Yusdiana, Armoni Suci Dewi, Fathiya Azka Putri, Ria Permata Sari","doi":"10.26891/jik.v17i1.2023.24-31","DOIUrl":"https://doi.org/10.26891/jik.v17i1.2023.24-31","url":null,"abstract":"Integrated Healthcare Center (Posyandu) provides access to the community for basic health access, especially for children under five. Indonesian Ministry of Health targeting children under five visit coverage at Posyandu by 90%. Children under five visit coverage to Posyandu at Tanah Putih Tj. Melawan public health center in 2019 only 37.2% of children under five visit coverage at Posyandu Melayu Besar by 42.8%. It is far from the expected target. The objective of this study is to determine factors influencing mother visitation to posyandu Melayu Besar, Rokan Hilir district. Fifty five mothers who have children between 1 – 5 years old were included in this study with accidental sampling. This observational study using a cross-sectional design. This study was conducted from August – October 2022. Collecting data using questionnaire and registration book for posyandu for visitation data. We analyze with univariate for distribution frequencies and bivariate using chi-square for relations. Most of the mothers who bring their children to posyandu are not working and high school graduates, with distance from home to posyandu not being a significant variable. Knowledge level about posyandu mostly in the “good” category by 60%. Number of children under five visit in the “routine” category by 61.8%. There is a correlation with mother visitation. Chi-Square (X 2 ) analysis earned p-value = 0,004 compare to α = 5% mean p < 0,05. In conclusion, there is a correlation between the mother’s knowledge with number of children under five visitation to posyandu.","PeriodicalId":207188,"journal":{"name":"Jurnal Ilmu Kedokteran (Journal of Medical Science)","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126225568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pott Puffy Tumor : Case Report 波特肿性肿瘤1例报告

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.90-96

Ade Wirdayanto, Hadiyan Adhli Muhammad

{"title":"Pott Puffy Tumor : Case Report","authors":"Ade Wirdayanto, Hadiyan Adhli Muhammad","doi":"10.26891/jik.v17i1.2023.90-96","DOIUrl":"https://doi.org/10.26891/jik.v17i1.2023.90-96","url":null,"abstract":"Pott puffy tumor (PPT) is an abscess of the subperiosteal os, frontalis. Frontalis subperiosteal abscess is often found in cranial osteomyelitis. Cranial osteomyelitis is an inflammatory process of the cranial bones, mainly caused by pyogenic organisms. The most common cause of cranial osteomyelitis in developing countries is paranasal sinusitis. One of the causes of PPT is an infection of the frontal sinus. Intracranial complications are the most common complications of PPT, one of which is a cerebral abscess in the frontal lobe. In this case report, the patient complained of forehead swelling that spread to both upper eyelids. There is a history of boils on the left side of the forehead since 3 weeks ago but was not treated medically. On physical examination, there was no neurological deficit. In the initial action, aspiration of the swelling results in the form of pus. Based on the results of a plain head CT scan and 3D skull bones, the results obtained were an appearance of an abscess in the subperiosteal frontal bone and osteomyelitis of the frontal bone. The patient underwent debridement craniectomy and further therapy in the form of intravenous antibiotics. As a follow-up examination, an examination of pus culture and examination of anatomical pathology were carried out, and obtained cranial osteomyelitis results but found no pathogenic germs.","PeriodicalId":207188,"journal":{"name":"Jurnal Ilmu Kedokteran (Journal of Medical Science)","volume":"275 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123081768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hubungan Kadar Polusi Udara dengan Kejadian Tuberkulosis di Kota Pekanbaru Tahun 2015 sampai dengan 2020

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.46-52

S. Suyanto, S. Aulia, Emillian Ramli, Fifia Chandra

引用次数: 0

Vaksin Terapeutik yang Menargetkan Onkoprotein E6 dan E7 pada Kanker Serviks 一种治疗性疫苗，目标是宫颈癌中的肿瘤E6和E7

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.11-16

Maya Savira

引用次数: 0

Perbandingan Mikroorganisme Pada Kultur Urin Pre-Operasi Dan Kultur Batu Pasca Operasi Pada Pasien Batu Saluran Kemih 术前尿液培养与泌尿科石头患者术后培养的微生物比较

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.59-65

Indra Jaya, Gatot Aji Prihartomo, Fathiyah Afaf

引用次数: 0

Aktifitas Antibiotik Ceftazidime-Avibactam Dan Ceftaroline Secara In Vitro Terhadap Isolat Klinis Di Pekanbaru ceftazidim - avibactam和Ceftaroline在Pekanbaru的临床隔离中进行体外研究

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.71-83

C. Wijaya

{"title":"Aktifitas Antibiotik Ceftazidime-Avibactam Dan Ceftaroline Secara In Vitro Terhadap Isolat Klinis Di Pekanbaru","authors":"C. Wijaya","doi":"10.26891/jik.v17i1.2023.71-83","DOIUrl":"https://doi.org/10.26891/jik.v17i1.2023.71-83","url":null,"abstract":"Ceftaroline and Ceftazidime–avibactam are relatively new antibiotics that show good effectiveness against antibiotic-resistant pathogens. Both of these antibiotics are now available worldwide, but reports of resistance to them are also starting to emerge. This study aimed to evaluate the in vitro activity of the antibiotic Ceftazidime-avibactam combination of 100 clinical isolates consisting of Enterobacteriaceae and Pseudomonas aeruginosa bacteria and to evaluate the antibiotic effect of Ceftaroline against 100 clinical isolates of Enterobacteriaceae and Staphylococcus sp. This study is observational with cross-sectional study design. The study was conducted at the microbiology laboratory of a private hospital at Pekanbaru Riau in Januari-June 2021. There were 100 clinical isolates tested with Ceftaroline and Ceftazidime-avibactam. The sensitivity to Ceftaroline and Ceftazidime-avibactam were reported as a number isolate and percentage. The results showed the sensitivity of bacteria K. pneumoniae, E. coli, Enterobacter sp, and P. aeruginosa, to Ceftazidime-Avibactam were 87%, 90%, 66%, and 82%, respectively. The sensitivity of the antibiotic Ceftaroline to the bacteria K. pneumoniae, E. coli, Enterobacter sp and Staphylococcus sp. were 39%, 54%, 36.4%, 67% and 75%, respectively. Based on these results, the antibiotic ceftazidime avibactam can be used for the treatment of suitable pathogenic infections because of its fairly good sensitivity (>80%) to Enterobacteriaceae and P. aeruginosa bacteria. Ceftaroline antibiotics are not recommended to be used as a therapeutic option, because of the high resistance to Enterobacteriaceae and Staphylococcus sp. Further research is needed to determine the molecular mechanism of resistance to Ceftaroline antibiotics","PeriodicalId":207188,"journal":{"name":"Jurnal Ilmu Kedokteran (Journal of Medical Science)","volume":"240 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121122667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pengaruh Ekstrak Buah Bakau (Rhizophora sp) terhadap Ekspresi Monocyte Chemoattractant Protein-1 pada Aorta Tikus Aterosklerosis

Jurnal Ilmu Kedokteran (Journal of Medical Science) Pub Date : 2023-05-08 DOI: 10.26891/jik.v17i1.2023.41-45

M. Y. Hamidy, Huriatul Masdar, Ayu Trisya Arti

引用次数: 0