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Lithium and the transfer rate of sodium across the blood-brain barrier 锂离子和钠离子通过血脑屏障的传输速率
Psychopharmacologia Pub Date : 2004-01-01 DOI: 10.1007/BF00403777
A. Amdisen, M. Schou
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引用次数: 1
Morphine-induced inhibition of different pain responses in relation to the regional turnover of rat brain noradrenaline and dopamine 吗啡诱导的不同疼痛反应的抑制与大鼠脑去甲肾上腺素和多巴胺的区域转换有关
Psychopharmacologia Pub Date : 2004-01-01 DOI: 10.1007/BF00426204
G. Paalzow, L. Paalzow
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引用次数: 15
Behavioral effects of intracerebrally administered catecholamines in mice and their modifications by some adrenergic blocking agents 脑内给药儿茶酚胺对小鼠行为的影响及其被一些肾上腺素能阻断剂所改变
Psychopharmacologia Pub Date : 2004-01-01 DOI: 10.1007/BF00426214
B. Pellegrini Quarantotti, A. S. Carolis, V. Longo
{"title":"Behavioral effects of intracerebrally administered catecholamines in mice and their modifications by some adrenergic blocking agents","authors":"B. Pellegrini Quarantotti, A. S. Carolis, V. Longo","doi":"10.1007/BF00426214","DOIUrl":"https://doi.org/10.1007/BF00426214","url":null,"abstract":"","PeriodicalId":20715,"journal":{"name":"Psychopharmacologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74321522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparison of the analgetic potency of some analgesics as measured by the “flinch-jump” procedure 用“退缩-跳跃”方法测定的几种镇痛药的镇痛效力的比较
Psychopharmacologia Pub Date : 2004-01-01 DOI: 10.1007/BF00413106
W. O. Evans
{"title":"A comparison of the analgetic potency of some analgesics as measured by the “flinch-jump” procedure","authors":"W. O. Evans","doi":"10.1007/BF00413106","DOIUrl":"https://doi.org/10.1007/BF00413106","url":null,"abstract":"","PeriodicalId":20715,"journal":{"name":"Psychopharmacologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79401764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Pharmacological dissociation between vocalization and biting produced in rats by the combination of imipramine and isocarboxazid 丙咪嗪和异嘧唑嗪联合用药对大鼠发声和咬伤的药理学分离作用
Psychopharmacologia Pub Date : 2004-01-01 DOI: 10.1007/BF00426212
G. Zetler, B. HÄuer
{"title":"Pharmacological dissociation between vocalization and biting produced in rats by the combination of imipramine and isocarboxazid","authors":"G. Zetler, B. HÄuer","doi":"10.1007/BF00426212","DOIUrl":"https://doi.org/10.1007/BF00426212","url":null,"abstract":"","PeriodicalId":20715,"journal":{"name":"Psychopharmacologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78697764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolism of 5-hydroxytryptophan-14c after intracisternal injection with and without the influence of drugs in the rat brain 5-羟色氨酸-14c在有和无药物影响的大鼠脑内注射后的代谢
Psychopharmacologia Pub Date : 2004-01-01 DOI: 10.1007/BF00426207
P. Baumann
{"title":"Metabolism of 5-hydroxytryptophan-14c after intracisternal injection with and without the influence of drugs in the rat brain","authors":"P. Baumann","doi":"10.1007/BF00426207","DOIUrl":"https://doi.org/10.1007/BF00426207","url":null,"abstract":"","PeriodicalId":20715,"journal":{"name":"Psychopharmacologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76851782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The effect of psychotropic drugs on food reinforced behaviour and on food consumption 精神药物对食物强化行为和食物消费的影响
Psychopharmacologia Pub Date : 2004-01-01 DOI: 10.1007/BF00403774
J. Bainbridge
{"title":"The effect of psychotropic drugs on food reinforced behaviour and on food consumption","authors":"J. Bainbridge","doi":"10.1007/BF00403774","DOIUrl":"https://doi.org/10.1007/BF00403774","url":null,"abstract":"","PeriodicalId":20715,"journal":{"name":"Psychopharmacologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84077409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Critical flicker frequency (CFF) and psychotropic drugs in normal human subjects-a review. 临界闪烁频率(CFF)与正常人的精神药物研究进展。
Psychopharmacologia Pub Date : 1976-05-28 DOI: 10.1007/BF00735818
J M Smith, H Misiak
{"title":"Critical flicker frequency (CFF) and psychotropic drugs in normal human subjects-a review.","authors":"J M Smith,&nbsp;H Misiak","doi":"10.1007/BF00735818","DOIUrl":"https://doi.org/10.1007/BF00735818","url":null,"abstract":"<p><p>This literature review presents summary methodological and statistical data on 33 studies in which critical flicker frequency (CFF) thresholds were used to evaluate the effects of acute oral doses of single psychotropic drugs in normal human subjects. In all, 96 drug-dose-study combinations are represented. CFF was found to be altered to a statistically significant degree (P is less than 0.05) in 51 (65%) of the 79 instances in which inferential statistical methods were used to evaluate the results. As expected, stimulants increased CFF while hypnotics decreased it. There is also a discussion of important methodological considerations in the design of psychopharmacological studies employing CFF. While many studies have shown CFF to be sensitive to the effects of psychotropic drugs, there have not always been adequate controls for extraneous factors (especially, set and suggestion, changes in pupillary diameter, and the presence of other commonly used drugs). Finally, consideration is given to the attempts to increase the sensitivity of the CFF test to drug effects.</p>","PeriodicalId":20715,"journal":{"name":"Psychopharmacologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1976-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00735818","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12448205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 108
Effect of doxepin on uptake and efflux of serotonin human blood patelets in vitro. 多虑平对体外人血小板5 -羟色胺摄取和排出的影响。
Psychopharmacologia Pub Date : 1976-05-28 DOI: 10.1007/BF00735819
O Lingjaerde
{"title":"Effect of doxepin on uptake and efflux of serotonin human blood patelets in vitro.","authors":"O Lingjaerde","doi":"10.1007/BF00735819","DOIUrl":"https://doi.org/10.1007/BF00735819","url":null,"abstract":"<p><p>It is shown that the tricyclic antidepressant drug doxepin (comprising 15% of the cis- and 85% of the trans-isomer) is a moderately potent competitive inhibitor of serotonin uptake in human blood platelets in vitro, with an inhibitory constant Ki of about 2 X 10(-7) M. The inhibitory effect was 6 times stronger in an artificial, protein-free medium than in diluted plasma, corresponding to about 85% protein binding. The efflux of serotonin from platelets preloaded with 14C-serotonin was not affected by doxepin in concentrations up to 10(-6) M, but increased rapidly at concentrations above 10(-4) M.</p>","PeriodicalId":20715,"journal":{"name":"Psychopharmacologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1976-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00735819","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12448206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Abolition of the hippocampal theta activity and drug-learning dissociation. 海马θ波活动的消除和药物学习解离。
Psychopharmacologia Pub Date : 1976-05-28 DOI: 10.1007/BF00735823
N Irisawa, S Iwahara, S Fukuda
{"title":"Abolition of the hippocampal theta activity and drug-learning dissociation.","authors":"N Irisawa,&nbsp;S Iwahara,&nbsp;S Fukuda","doi":"10.1007/BF00735823","DOIUrl":"https://doi.org/10.1007/BF00735823","url":null,"abstract":"<p><p>Rats were trained to escape electric shock by running into one arm of a T-maze on 10-trial daily sessions with pentobarbital (10 mg/kg), and to the opposite arm of the maze on other sessions with saline, the drug and saline sessions being alternated. This drug-learning dissociation or state-dependent learning was achieved by rats with medial septal lesions, abolishing hippocampal theta activity, as efficiently as rats with cortical lesions and intact rats. The suggested relationship between drug-learning dissociation and the suppression of hippocampal theta waves, produced by the drug, was not evidenced.</p>","PeriodicalId":20715,"journal":{"name":"Psychopharmacologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1976-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00735823","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12448209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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