Progress in the chemistry of organic natural products最新文献

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Sesterterpenoids. Sester萜烯类。
Progress in the chemistry of organic natural products Pub Date : 2020-01-01 DOI: 10.1007/978-3-030-37865-3_1
Takaaki Mitsuhashi, Ikuro Abe
{"title":"Sesterterpenoids.","authors":"Takaaki Mitsuhashi,&nbsp;Ikuro Abe","doi":"10.1007/978-3-030-37865-3_1","DOIUrl":"https://doi.org/10.1007/978-3-030-37865-3_1","url":null,"abstract":"<p><p>Sesterterpenoids are known as a relatively small group of natural products. However, they represent a variety of simple to more complex structural types. This contribution focuses on the chemical structures of sesterterpenoids and how their structures are constructed in Nature.</p>","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"111 ","pages":"1-79"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37690826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 54
Secondary Metabolites from Marine-Derived Fungi from China. 中国海生真菌次生代谢物研究。
Progress in the chemistry of organic natural products Pub Date : 2020-01-01 DOI: 10.1007/978-3-030-37865-3_2
Zhen Liu, Marian Frank, Xiaoqin Yu, Haiqian Yu, Nam M Tran-Cong, Ying Gao, Peter Proksch
{"title":"Secondary Metabolites from Marine-Derived Fungi from China.","authors":"Zhen Liu,&nbsp;Marian Frank,&nbsp;Xiaoqin Yu,&nbsp;Haiqian Yu,&nbsp;Nam M Tran-Cong,&nbsp;Ying Gao,&nbsp;Peter Proksch","doi":"10.1007/978-3-030-37865-3_2","DOIUrl":"https://doi.org/10.1007/978-3-030-37865-3_2","url":null,"abstract":"<p><p>Marine-derived fungi play an important role in the search for structurally unique secondary metabolites, some of which show promising pharmacological activities that make them useful leads for drug discovery. Marine natural product research in China in general has made enormous progress in the last two decades as described in this chapter on fungal metabolites. This contribution covers 613 new natural products reported from 2001 to 2017 from marine-derived fungi obtained from algae, sponges, corals, and other marine organisms from Chinese waters. The genera Aspergillus (170 new natural products, 28%) and Penicillium (70 new natural products, 11%) were the main fungal producers of new natural products during the time period covered, whereas sponges (184 new natural products, 30%) were the most abundant source of new natural products, followed by corals (154 new natural products, 25%) and algae (130 new natural products, 21%). Close to 40% of all natural products covered in this contribution displayed various bioactivities. The major bioactivities reported were cytotoxicity against different cancer cell lines, antimicrobial (mainly antibacterial) activity, and antiviral activity, which accounted for 13%, 9%, and 3% of all natural products reported. In terms of structural classes, polyketides (188 new natural products, 31%) play a dominant role, and if prenylated polyketides and nitrogen-containing polyketides (included in meroterpenes and alkaloids in this contribution) are taken into account, their total number even exceeds 50%. Nitrogen-containing compounds including peptides (65 new natural products, 10%) and alkaloids (103 new natural products, 17%) are the second largest group.</p>","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"111 ","pages":"81-153"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37690827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Chemical Diversity and Biological Activity of African Propolis. 非洲蜂胶的化学多样性和生物活性。
Progress in the chemistry of organic natural products Pub Date : 2019-10-22 DOI: 10.1007/978-3-030-12858-6_3
N. Blicharska, V. Seidel
{"title":"Chemical Diversity and Biological Activity of African Propolis.","authors":"N. Blicharska, V. Seidel","doi":"10.1007/978-3-030-12858-6_3","DOIUrl":"https://doi.org/10.1007/978-3-030-12858-6_3","url":null,"abstract":"","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"97 1","pages":"415-450"},"PeriodicalIF":0.0,"publicationDate":"2019-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85780048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Secondary Metabolites of Endophytic Actinomycetes: Isolation, Synthesis, Biosynthesis, and Biological Activities. 内生放线菌的次生代谢产物:分离、合成、生物合成和生物活性。
Progress in the chemistry of organic natural products Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-01099-7_3
Darlon Irineu Bernardi, Fernanda Oliveira das Chagas, Afif Felix Monteiro, Gabriel Franco Dos Santos, Roberto Gomes de Souza Berlinck
{"title":"Secondary Metabolites of Endophytic Actinomycetes: Isolation, Synthesis, Biosynthesis, and Biological Activities.","authors":"Darlon Irineu Bernardi,&nbsp;Fernanda Oliveira das Chagas,&nbsp;Afif Felix Monteiro,&nbsp;Gabriel Franco Dos Santos,&nbsp;Roberto Gomes de Souza Berlinck","doi":"10.1007/978-3-030-01099-7_3","DOIUrl":"https://doi.org/10.1007/978-3-030-01099-7_3","url":null,"abstract":"<p><p>Endophytic Actinobacteria are a microbial group that is still poorly investigated. Their association with plants constitutes a unique trait conferring specific biological and chemical features to endophytic Actinobacteria. This contribution discusses aspects of endophytic actinobacterial biology and chemistry comprehensively, including the biosynthesis and total synthesis of secondary metabolites produced in culture. It also presents perspectives for the future of microbial bioactive natural products discovery, with emphasis on the secondary metabolism of endophytic Actinobacteria.</p>","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"108 ","pages":"207-296"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-3-030-01099-7_3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37101992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Bioactive Compounds Involved in the Life Cycle of Higher Plants. 高等植物生命周期中的生物活性化合物。
Progress in the chemistry of organic natural products Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12858-6_2
H. Shigemori
{"title":"Bioactive Compounds Involved in the Life Cycle of Higher Plants.","authors":"H. Shigemori","doi":"10.1007/978-3-030-12858-6_2","DOIUrl":"https://doi.org/10.1007/978-3-030-12858-6_2","url":null,"abstract":"","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"100 1","pages":"385-413"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74401281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Chemistry of the Secondary Metabolites of Termites. 白蚁次生代谢产物的化学性质。
Progress in the chemistry of organic natural products Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12858-6_1
E. Gössinger
{"title":"Chemistry of the Secondary Metabolites of Termites.","authors":"E. Gössinger","doi":"10.1007/978-3-030-12858-6_1","DOIUrl":"https://doi.org/10.1007/978-3-030-12858-6_1","url":null,"abstract":"","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"218 1","pages":"1-384"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77241615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Cheminformatic Analysis of Natural Product Fragments. 天然产物片段的化学信息分析。
Progress in the chemistry of organic natural products Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-14632-0_5
D. Reker
{"title":"Cheminformatic Analysis of Natural Product Fragments.","authors":"D. Reker","doi":"10.1007/978-3-030-14632-0_5","DOIUrl":"https://doi.org/10.1007/978-3-030-14632-0_5","url":null,"abstract":"","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"18 1","pages":"143-175"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76365249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resources for Chemical, Biological, and Structural Data on Natural Products. 天然产物的化学、生物和结构数据资源。
Progress in the chemistry of organic natural products Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-14632-0_2
Ya Chen, Christina de Bruyn Kops, J. Kirchmair
{"title":"Resources for Chemical, Biological, and Structural Data on Natural Products.","authors":"Ya Chen, Christina de Bruyn Kops, J. Kirchmair","doi":"10.1007/978-3-030-14632-0_2","DOIUrl":"https://doi.org/10.1007/978-3-030-14632-0_2","url":null,"abstract":"","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"199 1","pages":"37-71"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86410796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
The Pharmacophore Concept and Its Applications in Computer-Aided Drug Design. 药效团概念及其在计算机辅助药物设计中的应用。
Progress in the chemistry of organic natural products Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-14632-0_4
T. Seidel, D. Schuetz, A. Garon, T. Langer
{"title":"The Pharmacophore Concept and Its Applications in Computer-Aided Drug Design.","authors":"T. Seidel, D. Schuetz, A. Garon, T. Langer","doi":"10.1007/978-3-030-14632-0_4","DOIUrl":"https://doi.org/10.1007/978-3-030-14632-0_4","url":null,"abstract":"","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"55 1","pages":"99-141"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73425354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 35
A Strength-Weaknesses-Opportunities-Threats (SWOT) Analysis of Cheminformatics in Natural Product Research. 天然产物研究中化学信息学的优势-劣势-机会-威胁(SWOT)分析
Progress in the chemistry of organic natural products Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-14632-0_7
B. Kirchweger, J. Rollinger
{"title":"A Strength-Weaknesses-Opportunities-Threats (SWOT) Analysis of Cheminformatics in Natural Product Research.","authors":"B. Kirchweger, J. Rollinger","doi":"10.1007/978-3-030-14632-0_7","DOIUrl":"https://doi.org/10.1007/978-3-030-14632-0_7","url":null,"abstract":"","PeriodicalId":20703,"journal":{"name":"Progress in the chemistry of organic natural products","volume":"6 1","pages":"239-271"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75250622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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