Suraj Aswale, Hyerin Kang, Aruna Kumar Mohanty, Hanyoung Kim, Yerin Jang, Minsung Kim, Heung Bae jeon, Hong Y. Cho, Hyun-jong Paik
{"title":"Various Topological Poly(tert-butyl acrylate)s and Their Impacts on Thermal and Solution Properties","authors":"Suraj Aswale, Hyerin Kang, Aruna Kumar Mohanty, Hanyoung Kim, Yerin Jang, Minsung Kim, Heung Bae jeon, Hong Y. Cho, Hyun-jong Paik","doi":"10.1002/marc.70002","DOIUrl":"https://doi.org/10.1002/marc.70002","url":null,"abstract":"<p><b>Front Cover</b>: Topologically diverse poly(t-butyl acrylate)s including linear, tetra-arm, cyclic, and 8-shaped architectures, are synthesized via ARGET ATRP and CuAAC click chemistry. Despite similar molar masses, distinct thermal and solution behaviors are observed. These findings highlight the critical role of topology in tuning polymer properties for applications in adhesives, nanomaterials, etc. More details can be found in article 2401043 by Hong Y. Cho, Hyun-jong Paik, and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":"46 15","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/marc.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hatice Mutlu, Bercis Pektas, C Remzi Becer, Azra Kocaarslan
{"title":"Green and Sustainable Chemistry Approaches on Azide-Based Click Reactions in Polymer Science.","authors":"Hatice Mutlu, Bercis Pektas, C Remzi Becer, Azra Kocaarslan","doi":"10.1002/marc.202500171","DOIUrl":"https://doi.org/10.1002/marc.202500171","url":null,"abstract":"<p><p>Click Chemistry, particularly the azide-alkyne cycloaddition (AAC) reaction, has revolutionized polymer chemistry, enabling precise and efficient synthesis of advanced functional materials. With its high regioselectivity, mild reaction conditions, and versatility, AAC reactions align closely with the principles of Green and Sustainable Chemistry. However, the core principles of Click Chemistry, particularly its compatibility with Green Chemistry ideals-such as reduced waste, high atom economy, and mild reaction conditions-remain insufficiently emphasized in the context of polymer chemistry. The review evaluates current limitations in AAC-particularly the challenges associated with hazardous azide reagents and reliance on non-renewable resources-and explores innovative solutions, including greener catalysts, solvent-free systems, and the incorporation of renewable feedstocks. Additionally, the review presents a comparison of activation methods, spanning thermal, catalytic, metal-free, and strain-promoted pathways, to highlight their respective advantages and trade-offs in sustainability. Practical applications of AAC in polymer design are discussed, showcasing its role in creating materials with tailored properties such as thermal stability, bioactivity, and electronic functionality. This analysis provides a roadmap for future research to optimize AAC for sustainability without compromising its effectiveness in materials design.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e00171"},"PeriodicalIF":4.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144787922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction: Structural and Property Characterizations of Dual-Responsive Core–Shell Tecto Dendrimers for Tumor Penetration and Gene Delivery Applications","authors":"","doi":"10.1002/marc.202500596","DOIUrl":"10.1002/marc.202500596","url":null,"abstract":"<p>Junjie Liu, Xiaoyu Wang, Xiaolei Li, et al., <i>Macromol. Rapid Commun</i>. <b>2024</b>, 45, 2400251, https://doi.org/10.1002/marc.202400251.</p><p>The authors regret that the original version of our paper contained an incorrect picture in Figure 7A, where the image of “N/P = 5” in the P-Glu/Cas9-PD-L1 group was mistakenly replaced with the P-Gal/Cas9-PD-L1 image during data organization. The corrected Figure 7 is shown below. This correction does not affect the validity of the original discussion, interpretation, and conclusion presented in this paper. The authors sincerely apologize to the Journal and its readers for the confusion that may have caused.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":"46 16","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/marc.202500596","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Warisha Mehmood, Muhammad Gulraiz Tanvir, Kamran Amin, Zhixiang Wei
{"title":"Designing Solution-Processable Covalent Organic Frameworks: Opportunities and Challenges.","authors":"Warisha Mehmood, Muhammad Gulraiz Tanvir, Kamran Amin, Zhixiang Wei","doi":"10.1002/marc.202500328","DOIUrl":"https://doi.org/10.1002/marc.202500328","url":null,"abstract":"<p><p>Since their discovery, numerous covalent organic frameworks (COFs) have been reported, showcasing unique properties that make them materials of choice for a wide range of applications. COFs have gained significant attention due to their fascinating characteristics, such as tunable pore structures, customizable functionality, and high crystallinity. Despite substantial progress in this field, the widespread application of COFs remains limited due to challenges in large-scale synthesis, issues with repeatability, and poor solubility, which hinder their processability. We propose that the lack of solution processability represents the most significant challenge hindering the application of COFs across various fields. Recognizing the importance of this issue and aiming to highlight the challenges in this direction, we have summarized the available data and previous attempts made to address these limitations. This review provides an insightful analysis of the current issues and future challenges, while also proposing strategies to overcome these challenges. The review not only summarizes all the relevant issues but also aims to inspire researchers to investigate these challenges in greater detail.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e00328"},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guohua Hang, Xibin Shen, Yawei Zhang, Lei Li, Tao Zhang, Sixun Zheng
{"title":"From Octamethylcyclotetrasiloxane to Reprocessable and Recyclable Networks of Polydimethylsiloxane via One-Pot Reactions.","authors":"Guohua Hang, Xibin Shen, Yawei Zhang, Lei Li, Tao Zhang, Sixun Zheng","doi":"10.1002/marc.202500456","DOIUrl":"https://doi.org/10.1002/marc.202500456","url":null,"abstract":"<p><p>Polydimethylsiloxane (PDMS) networks were generated with octamethylcyclotetrasiloxane (D4) and 1,4-bis(heptaisobutylPOSS)dipropoxybutane (denoted diPOSS) via a one-pot reaction approach, which was mediated with tetrabutylammonium fluoride (TBAF). The reaction involving the formation of PDMS networks included: (i) the fluoride-initiated anionic ring-opening polymerization (ROP) of D4, and (ii) the rearrangement of siloxane. By varying the feed ratios of D4 to diPOSS, the PDMS-POSS networks were obtained with variable crosslinking densities, having tunable thermal and mechanical properties. Benefiting from the incorporation of TBAF, the crosslinked networks can be reprocessed without sacrificing their mechanical strengths. Furthermore, the PDMS-POSS networks can be depolymerized into oligomeric siloxanes with the aid of a polar solvent (i.e., tetrahydrofuran). Upon removing the solvent, the networks can be regenerated with the reverted mechanical strengths.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e00456"},"PeriodicalIF":4.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benzocyclobutenyl Silicone-Acrylic Resin: A Photo/Thermal Curing Hybrid Structure for High-Performance Photoimageable Dielectrics.","authors":"Wei Chen, Jiajun Ma, Xu Ye, Junxiao Yang","doi":"10.1002/marc.202500411","DOIUrl":"https://doi.org/10.1002/marc.202500411","url":null,"abstract":"<p><p>Advancements in integrated circuit technology have heightened the importance of photoresist materials with superior dielectric properties, thermal stability, and patterning precision. Although traditional acrylic resins exhibit excellent photo-curing characteristics, their high dielectric constants, limited thermal stability, and hygroscopic nature restrict their utility in semiconductor applications. In this study, 4-acryloylbenzocyclobutene (BCB-V-COOH) was synthesized via a Heck reaction between 4-bromobenzocyclobutene and acrylic acid. Subsequently, BCB-V-COOH was copolymerized with bisbenzocyclobutene-bis-divinylsiloxane (DVS-b-BCB) at varying ratios to produce the oligomer BCB-SO-COOH. These oligomers were then graft-modified with glycidyl methacrylate to yield BSA Resin, which was blended with the photoinitiator to formulate photoresists. The structures of the BSA Resins were characterized using proton nuclear magnetic resonance (<sup>1</sup>H NMR) and Fourier transform infrared (FTIR) spectroscopy. Studies on the photo-thermal curing kinetics revealed that the acrylate double bonds rapidly crosslinked under 365 nm UV irradiation, while the BCB moieties formed crosslinked networks via a ring-opening mechanism during thermal curing. The incorporation of BCB significantly enhanced the thermal stability and dielectric properties of the BSA Resins. Moreover, the BSA Resin achieved a patterning resolution of 10 µm with exceptional dimensional stability. Therefore, this work demonstrates the promising potential of BSA Resin for applications in microelectronic packaging.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e00411"},"PeriodicalIF":4.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wei Ge, Ramindu De Silva, Yanan Fan, Scott A Sisson, Martina H Stenzel
{"title":"Predictive Modelling of Solvent Effects on Drug Incorporation into Polymeric Nanocarriers: A Machine Learning Approach.","authors":"Wei Ge, Ramindu De Silva, Yanan Fan, Scott A Sisson, Martina H Stenzel","doi":"10.1002/marc.202500251","DOIUrl":"https://doi.org/10.1002/marc.202500251","url":null,"abstract":"<p><p>This study aimed to identify solvent characteristics that enhance drug loading in polymeric micelles. Polyethylene glycol-block-polystyrene (PEG-b-PS) and curcumin were used as model compounds to investigate the impact of 40 different solvent mixtures on drug loading during flow-based assembly. We tested five algorithms: Random Forest (RF), Gradient Boosting (GP), XGBoost, Support Vector Regression (SVR), and Multilayer Perceptron (MLP), with the MLP model proving to be the most effective among them. To explain the model's predictions, we utilized SHapley Additive exPlanations (SHAP) values to identify solvent properties that contribute to high drug loading. Of the nine descriptors examined-curcumin solubility, polarity, Hildebrand solubility parameters, dipole moment, dielectric constants, viscosity, and Hansen solubility parameters (δD, δP, and δH)-solubility emerged as the most critical factor. Therefore, to achieve optimal drug loading, researchers should prioritize solvents with the highest solubility.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e00251"},"PeriodicalIF":4.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144751864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam W Woodhouse, Bercis Pektas, Cuong M Q Le, Jennifer A Garden, Hatice Mutlu
{"title":"Lauric Diacid-Derived Sulfur-Decorated Functional Polymers Displaying Programmable Thermal and Unconventional Luminescence Properties by Simple Thionation.","authors":"Adam W Woodhouse, Bercis Pektas, Cuong M Q Le, Jennifer A Garden, Hatice Mutlu","doi":"10.1002/marc.202500056","DOIUrl":"https://doi.org/10.1002/marc.202500056","url":null,"abstract":"<p><p>Aliphatic polythioesters (featuring the (C═O)─S linkage) are recognized as useful complements to polyesters that possess intriguing properties, such as high optical features, metal coordination ability and affinity for metal surfaces, self-healing capability, and improved crystallinity amongst others. Still, conventional synthetic approaches often require the use of toxic acyl chlorides. Thus, in this study, two semi-crystalline polythioesters, P1 and P2, were synthesized via a step-growth polycondensation between a long-chain bioderived diacid (1,12-dodecanedioic acid, aka lauric diacid) and two commercially available dithiols, namely, 1,6-hexanedithiol or 2,2'-(ethylenedioxy)diethanethiol). The activation was achieved using 1,1'-carbonyldiimidazole, which eliminates the need for acyl chlorides and leads to the formation of a useful by-product, 1,8-diazabicycloundec-7-ene imidazolium salt. An exemplary polythioester (i.e., P2) underwent a previously less-reported post-polymerization modification (hereafter referred to as modification, for clarity) with Lawesson's reagent to yield polydithioester PP2. This transformation induced a distinct change in material behavior, converting a semi-crystalline structure (melting temperature: 67.7°C) into an amorphous one characterized by a glass transition temperature of -40°C, and significantly reducing its luminescent response. Thus, this study provides a more sustainable synthetic platform for the development of functional polythioesters with tunable thermal and optical properties.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e00056"},"PeriodicalIF":4.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144751949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metal-Free Multicomponent Upcycling of Polybutadiene to Sulfonamide-Functionalized Materials.","authors":"Janna Jeschke, Jan Hobich, Hatice Mutlu","doi":"10.1002/marc.202500311","DOIUrl":"https://doi.org/10.1002/marc.202500311","url":null,"abstract":"<p><p>We report a catalyst-free, one-pot method for the upcycling of liquid polybutadiene that enables simultaneous backbone editing and introduction of sulfonamide and bromine functionalities under mild conditions. This sustainable alternative to metal-catalyzed approaches, such as selenium-based methods, offers access to functional polymers with tunable thermal and interfacial properties. The introduced bromine groups enable further orthogonal modifications, exemplified by efficient azidation. Remarkably, the resulting materials display previously unreported non-conventional luminescence behavior, expanding the functional scope of upcycled commodity polymers and opening pathways toward applications in sensing, coatings, and bioimaging.</p>","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e00311"},"PeriodicalIF":4.3,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144740753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}