Macromolecular Rapid Communications最新文献_第10页

Electrospinning in Drug Delivery: Progress and Future Outlook.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-20 DOI: 10.1002/marc.202400903

Nurfitrah Halim, Nithiskanna Nallusamy, Rajamani Lakshminarayanan, Seeram Ramakrishna, Sevakumaran Vigneswari

{"title":"Electrospinning in Drug Delivery: Progress and Future Outlook.","authors":"Nurfitrah Halim, Nithiskanna Nallusamy, Rajamani Lakshminarayanan, Seeram Ramakrishna, Sevakumaran Vigneswari","doi":"10.1002/marc.202400903","DOIUrl":"https://doi.org/10.1002/marc.202400903","url":null,"abstract":"There is intense research during the past few decades to design and fabricate drug delivery systems using the electrospinning system. Electrospinning is an efficient technique to produce nanofiber materials with different dimensions and morphologies by adjusting the processing parameters. Electrospinning is becoming an innovative technology that promotes the pursuit and maintenance of human health. Herein, the review discusses the contribution of electrospinning technology in drug delivery systems, summarising the modification of the various electrospinning system configurations and the effects of the process parameters on fibers, their application in drug delivery including carrier materials, loaded drugs and their release mechanisms and illustrates their various medical applications. Finally, this review discusses the challenges, bottlenecks, and development prospects of electrospinning technology in the field of drug delivery in terms of scaling up for clinical use and exploring potential solutions to pave the way to establish electrospinning for future drug delivery systems.","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e2400903"},"PeriodicalIF":4.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Facile Strategy to Construct Stretchable and Thermoreversible Double Network Hydrogels with Low Hysteresis and High Toughness Based on Entanglement and Hydrogen Bond Networks.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-17 DOI: 10.1002/marc.202401134

Kun Lei, Qixiu Jiang, Xinling Wang, Dianhao Gong

{"title":"A Facile Strategy to Construct Stretchable and Thermoreversible Double Network Hydrogels with Low Hysteresis and High Toughness Based on Entanglement and Hydrogen Bond Networks.","authors":"Kun Lei, Qixiu Jiang, Xinling Wang, Dianhao Gong","doi":"10.1002/marc.202401134","DOIUrl":"https://doi.org/10.1002/marc.202401134","url":null,"abstract":"High toughness and low hysteresis are of great significance for stretchable hydrogels to strengthen their reliability and practicability for cycle-loaded applications. Whereas, it is still challenging to simultaneously gain mutually repulsive properties due to the existence of dissipation structure. Here, stretchable and recoverable double network (DN) hydrogels comprising highly entangled network structure and temperature-induced dense hydrogen bond (HB)-associated network structure are synthesized, in which slidable entanglements and dense HBs act as the effective crosslinking in first and second networks, respectively. Moveable entanglements and stable HB structures endow hydrogels with high stretchability (999%), high tensile strength (0.82 MPa) and high fracture toughness (4.51 MJ·m-3) through stress transmission along long chains and HB clusters energy dissipation. Moreover, the imposed energy on hydrogels can saved in oriented polymer chains by disentanglement as an entropy loss, thus ensuring the low hysteresis (6.2% at 100% tensile strain) of hydrogels. In addition, deformed hydrogel can be well remodeled and recovered (stress recovery of 95.5%) by temperature-triggered sol-gel transition of HB network. By means of entanglement and hydrogen bond strategies, stretchable DN hydrogels not only equilibrate the conflict of low hysteresis and high toughness, but also provides a new perspective to design high-property hydrogels for cycle-loaded applications.","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e2401134"},"PeriodicalIF":4.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interfacially Assembled Fluorescent Nanofilm for Ultra-Sensitive Formic Acid Detection via Hydrogen Bonding Affinity and Recognition.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-17 DOI: 10.1002/marc.202401048

Linxuan Huang, Xinxiang Gao, Xinyao Mao, Ishfaq Ullah, Zhijie Zhou, Ejaz Hussain, Yinghui Xiao, Haonan Peng, Yu Fang

{"title":"Interfacially Assembled Fluorescent Nanofilm for Ultra-Sensitive Formic Acid Detection via Hydrogen Bonding Affinity and Recognition.","authors":"Linxuan Huang, Xinxiang Gao, Xinyao Mao, Ishfaq Ullah, Zhijie Zhou, Ejaz Hussain, Yinghui Xiao, Haonan Peng, Yu Fang","doi":"10.1002/marc.202401048","DOIUrl":"https://doi.org/10.1002/marc.202401048","url":null,"abstract":"High-performance film-based sensors are key innovations driving advancements in sensing technologies. An ultra-sensitive formic acid sensor based on a polymer fluorescent nanofilm synthesized via interfacial assembly using a tetraphenylethylene derivative functionalized with aldehyde and hydroxyl groups is reported. These groups promote imine bond formation and enhance selectivity. The nanofilm, prepared through dynamic condensation with 4,4'-diaminodiphenyl ether at the air-DMSO interface, exhibits excellent luminescence, flexibility, and tunable surface topography. Its bright fluorescence is primarily due to the aggregation-induced emission (AIE) property and hydrogen bonding interactions within the film structure. Imines serve as recognition sites for formic acid, where weak hydrogen bonding alters the electronic environment of the imine groups, blocking proton donors (─OH) and promoting non-radiative decay, leading to selective fluorescence quenching. The sensor achieves an ultra-low detection limit of 550 ppt, a rapid response time of 0.3 s, and excellent reversibility. It also demonstrates high selectivity for formic acid over other VOCs, making it suitable for real-time monitoring. Additionally, the nanofilm's multimodal sensing capabilities, including responses to HCl and NH3, highlight its potential for diverse environmental and industrial applications.","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e2401048"},"PeriodicalIF":4.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indacenodithiophene-Based Medium-Bandgap Guest Acceptor Enables High-Efficiency Ternary Organic Solar Cells.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-14 DOI: 10.1002/marc.202401005

Nailiang Qiu, Chunyan Liu, Tengteng Zhang, Jiaxuan Li, Wenhui Zhang, Jun Yan, Shiqun You, Yan Lu

{"title":"Indacenodithiophene-Based Medium-Bandgap Guest Acceptor Enables High-Efficiency Ternary Organic Solar Cells.","authors":"Nailiang Qiu, Chunyan Liu, Tengteng Zhang, Jiaxuan Li, Wenhui Zhang, Jun Yan, Shiqun You, Yan Lu","doi":"10.1002/marc.202401005","DOIUrl":"https://doi.org/10.1002/marc.202401005","url":null,"abstract":"The ternary organic solar cells (OSCs) have been proven to be an effective strategy for achieving high power conversion efficiency (PCE), exhibiting substantial potential for continuous enhancement of device performance. In this work, a novel nonfullerene acceptor, IDT-FN, is developed utilizing a renowned indacenodithiophene (IDT) core and moderately intense electron-withdrawing terminal groups, serving as the third component in ternary OSCs. IDT-FN demonstrates excellent complementary light absorption and cascaded energy levels with the host materials D18 and CH-6F, resulting in enhanced photon harvesting and charge transport within the ternary blend. Therefore, even the as-cast ternary device manages to surpass the optimal binary host device, achieving a superior PCE of 17.34% compared to the latter's 17.08%. Through optimization, the optimal ternary devices attain an impressive PCE of 18.32%, accompanied by a high open-circuit voltage (Voc) of 0.897 V, a fill factor of 0.745, and a short-circuit current density (Jsc) of 27.41 mA cm-2. This demonstrates a significant success in utilizing IDT-based medium-bandgap guests to achieve state-of-the-art ternary OSCs.","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e2401005"},"PeriodicalIF":4.2,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphology of Nanometer-Sized PEDOT:PSS Nanoparticles.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-14 DOI: 10.1002/marc.202500045

Zixian Zhang, Xinlu Liu, Qi Luo, Xianmin Zhou, Qijin Zhou, Yang Liu, Yinhua Zhou

引用次数: 0

Hemiacetal Ester Side Chains as a Mild Protecting Group for Carboxylic Acids in Polycarbonate Backbones.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-14 DOI: 10.1002/marc.202500082

Leon Bixenmann, Lutz Nuhn

引用次数: 0

Mesoporous Semi-Permeable Flexible Polyurethane Membranes: Advancing Bioartificial Pancreas Design for Type 1 Diabetes Treatment.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-14 DOI: 10.1002/marc.202500049

Bryan Gross, Emeline Lobry, Séverine Sigrist, Elisa Maillard, Jordan Magisson, Charles-Thibault Burcez, Manuel Pires, Anne Hébraud, Guy Schlatter

{"title":"Mesoporous Semi-Permeable Flexible Polyurethane Membranes: Advancing Bioartificial Pancreas Design for Type 1 Diabetes Treatment.","authors":"Bryan Gross, Emeline Lobry, Séverine Sigrist, Elisa Maillard, Jordan Magisson, Charles-Thibault Burcez, Manuel Pires, Anne Hébraud, Guy Schlatter","doi":"10.1002/marc.202500049","DOIUrl":"https://doi.org/10.1002/marc.202500049","url":null,"abstract":"This study reports the development of elastomeric mesoporous polyurethane (PU) membranes for bioartificial pancreas applications in type 1 diabetes treatment. The membranes are designed to exhibit semi-permeable properties, enabling insulin diffusion while restricting larger immune molecules, such as immunoglobulin G (IgG). Although electrospinning is a widely used technique for fabricating porous membranes for controlled drug release, it typically results in an average pore size on the order of few micrometers, which is two orders of magnitude larger than the mesoporous scale required. In this work, a green-electrospinning process using waterborne PU suspension and poly(ethylene oxide) (PEO) is employed, followed by thermal annealing and washing steps. The resulting membranes exhibit a controlled pore size in the mesoporous range (≈20 nm measured by capillary flow porometry). Diffusion tests confirmed selective permeability, with a recovery rate of 25% for insulin and a recovery rate below 5% for IgG, meeting therapeutic needs. In vivo characterizations show no degradation and good biocompatibility of the membranes without chronic inflammation. Moreover, mechanical characterization demonstrates the membranes' flexibility and strength, making them suitable for minimally invasive surgical implantation. These findings underscore the potential of PU membranes for long-term biomedical applications, addressing critical challenges in permeability and mechanical stability.","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e2500049"},"PeriodicalIF":4.2,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ionogel Adhesives: From Structural Design to Emerging Applications.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-14 DOI: 10.1002/marc.202400973

Yangyu Huang, He Zhu, Qi Zhang, Shiping Zhu

{"title":"Ionogel Adhesives: From Structural Design to Emerging Applications.","authors":"Yangyu Huang, He Zhu, Qi Zhang, Shiping Zhu","doi":"10.1002/marc.202400973","DOIUrl":"https://doi.org/10.1002/marc.202400973","url":null,"abstract":"Adhesives are indispensable in both daily household applications and advanced industrial settings, where they must deliver exceptional bonding performance. Ionogel adhesives, which feature a supporting polymer network infused with ionic liquid (IL), have emerged as promising candidates due to their unique structural and functional properties. The presence of ionic species within ionogels promotes non-covalent interactions-such as ionic bonds, ion-dipole interactions, and hydrogen bonding-that enhance both cohesion within the material and adhesion to various substrates. These characteristics make ionogels ideal for applications that require robust adhesive performance, especially in demanding environments. Despite the growing interest in ionogel adhesives, a comprehensive review of the latest advancements in this area is lacking. This paper aims to fill this gap by categorizing ionogel adhesives based on their composition and discussing strategies to enhance their adhesive properties. Additionally, novel ionogel adhesives designed for specific applications are highlighted. Finally, the current state of research is summarized, and offers insights into the challenges and future opportunities for the development of ionogel adhesives.","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e2400973"},"PeriodicalIF":4.2,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rational Design of Covalent Organic Frameworks for Photocatalytic Hydrogen Peroxide Production.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-12 DOI: 10.1002/marc.202401149

Yang Ou, Yifan Zhang, Wen Luo, Yang Wu, Yong Wang

{"title":"Rational Design of Covalent Organic Frameworks for Photocatalytic Hydrogen Peroxide Production.","authors":"Yang Ou, Yifan Zhang, Wen Luo, Yang Wu, Yong Wang","doi":"10.1002/marc.202401149","DOIUrl":"https://doi.org/10.1002/marc.202401149","url":null,"abstract":"Photocatalytic production of hydrogen peroxide (H2O2) represents a significant approach to achieving sustainable energy generation through solar energy, addressing both energy shortages and environmental pollution. Among various photocatalytic materials, covalent organic frameworks (COFs) have gained widespread attention and in-depth research due to their unique advantages, including high porosity, predesignability, and atomic-level tunability. In recent years, significant progress has been made in the development, performance enhancement, and mechanistic understanding of COF-based photocatalysts. This review focuses on the latest advancements in photocatalytic H2O2 production using COFs, particularly emphasizing the rational design of COF structures to regulate catalytic performance and exploring the fundamental processes involved in photocatalysis. Based on current research achievements in this field, this paper also discusses existing challenges and future opportunities, aiming to provide a reference for the application of COFs in photocatalytic H2O2 production.","PeriodicalId":205,"journal":{"name":"Macromolecular Rapid Communications","volume":" ","pages":"e2401149"},"PeriodicalIF":4.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renewable Phenolic Resins Based on Nitrogen-Coordinated Cyclic Boronic Ester Bonds.

IF 4.2 3区化学

Macromolecular Rapid Communications Pub Date : 2025-02-12 DOI: 10.1002/marc.202400826

Lu Wang, Yuyao Chang, Yu Luo, Yijie Zhang, Xinli Jing, Wei Fan, Shujuan Wang

引用次数: 0